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The map label for this gene is yrbG [H]

Identifier: 78188918

GI number: 78188918

Start: 1288189

End: 1289112

Strand: Reverse

Name: yrbG [H]

Synonym: Cag_0950

Alternate gene names: 78188918

Gene position: 1289112-1288189 (Counterclockwise)

Preceding gene: 78188919

Following gene: 78188916

Centisome position: 50.12

GC content: 41.45

Gene sequence:

>924_bases
ATGGAATACCTTTTATTACTTCTTGGTATTGCTTGTGCCGCATTTGGAGGAGAACTCTTTATTCGTGGTGCCGTTGGCAT
TGCTTATGCTGCTCGAATTAAGCCGGCTATTATTGGGGTTACCATAGCAGCTTTTGCCACCTCCAGCCCCGAACTCTCCA
TTGCTATTAATGCTGGCGCCTCCCAACACAGCAGCATTGCCCTTGGTGATACACTTGGTAGCAATATTGTAAACGTATCC
TTTATTTTAGCCGTAGCACTCTTAATCTCTCCAATTTCTGTTAGCAAAAGCACGACTCAACGCGACTTTACTCTTGCACT
TTTTGTTCCTATCGTTAGTGCGGTGTTACTTTTAGATAATGAACTATCACGTTTTGATGGTGCTATACTTCTTACACTCT
TTATAGGGTGGCTTATAGCAGCTATTGTAGAGGCTAAAAAAGATCGCAAAAAAACATTGCATCAAGAAAATGTACAAACG
TTACGAAAATATGTGTTACCAACGCTTATAGGGTTAGTAATGCTGTTTGCTGCTGGTAATTTTATTGTAACAAGCGCCAC
CACCATTGCAAAGTCGTTTGGAGTGAATGATTTTCTCATTGGCGCAACCATTGTAGCTTTAGGTACCTCAGTACCAGAAC
TTGCCTCTACCATTATGGCAAAAATTCGTGGTCATAACGACATGAGCTTAGGTACCATTCTTGGTAGCAACATTTTTAAC
GGCTTACTTATTGTAGCCACCGCTGCCTTGCTTAATCCAATTACCATTACCTTTCAAGAGGTACTGCCGACAATAGCATT
TGGCATTGCTGTGTTGCTCTTTTCTTATCCGTACCGCAACAATACGATTACCCGTTTACAAGGAGGGCTGTTACTCATGC
TTTACTTTGCCTATCTTGGCGTTATGATTTGGACTCAAACATAA

Upstream 100 bases:

>100_bases
TAGAGACCTTCAAAAAGAGGCAACCGTTGAAGCGTACCGTTTGTTATCACAACTTCTTGCAAACGTGCTGTTGCATTAAA
AGAAACAGAAAAACAATAGT

Downstream 100 bases:

>100_bases
ACATTGTGAACAACGCTCTGATAAGAGAAAGTACAATGAACGACTTTTGAATTTTTTGATACTTTGTAGATAGTAAAACA
GAATAATTTTAGATGCAAAA

Product: K+-dependent Na+/Ca+ exchanger-like protein

Products: Na (I) [Cytoplasm]; Ca (II) [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MEYLLLLLGIACAAFGGELFIRGAVGIAYAARIKPAIIGVTIAAFATSSPELSIAINAGASQHSSIALGDTLGSNIVNVS
FILAVALLISPISVSKSTTQRDFTLALFVPIVSAVLLLDNELSRFDGAILLTLFIGWLIAAIVEAKKDRKKTLHQENVQT
LRKYVLPTLIGLVMLFAAGNFIVTSATTIAKSFGVNDFLIGATIVALGTSVPELASTIMAKIRGHNDMSLGTILGSNIFN
GLLIVATAALLNPITITFQEVLPTIAFGIAVLLFSYPYRNNTITRLQGGLLLMLYFAYLGVMIWTQT

Sequences:

>Translated_307_residues
MEYLLLLLGIACAAFGGELFIRGAVGIAYAARIKPAIIGVTIAAFATSSPELSIAINAGASQHSSIALGDTLGSNIVNVS
FILAVALLISPISVSKSTTQRDFTLALFVPIVSAVLLLDNELSRFDGAILLTLFIGWLIAAIVEAKKDRKKTLHQENVQT
LRKYVLPTLIGLVMLFAAGNFIVTSATTIAKSFGVNDFLIGATIVALGTSVPELASTIMAKIRGHNDMSLGTILGSNIFN
GLLIVATAALLNPITITFQEVLPTIAFGIAVLLFSYPYRNNTITRLQGGLLLMLYFAYLGVMIWTQT
>Mature_307_residues
MEYLLLLLGIACAAFGGELFIRGAVGIAYAARIKPAIIGVTIAAFATSSPELSIAINAGASQHSSIALGDTLGSNIVNVS
FILAVALLISPISVSKSTTQRDFTLALFVPIVSAVLLLDNELSRFDGAILLTLFIGWLIAAIVEAKKDRKKTLHQENVQT
LRKYVLPTLIGLVMLFAAGNFIVTSATTIAKSFGVNDFLIGATIVALGTSVPELASTIMAKIRGHNDMSLGTILGSNIFN
GLLIVATAALLNPITITFQEVLPTIAFGIAVLLFSYPYRNNTITRLQGGLLLMLYFAYLGVMIWTQT

Specific function: Unknown

COG id: COG0530

COG function: function code P; Ca2+/Na+ antiporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Homo sapiens, GI300796347, Length=143, Percent_Identity=30.7692307692308, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI9966787, Length=143, Percent_Identity=30.7692307692308, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1789587, Length=231, Percent_Identity=34.6320346320346, Blast_Score=112, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24583109, Length=144, Percent_Identity=29.8611111111111, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24583111, Length=144, Percent_Identity=29.8611111111111, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004481
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 32592; Mature: 32592

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYLLLLLGIACAAFGGELFIRGAVGIAYAARIKPAIIGVTIAAFATSSPELSIAINAGA
CHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHCHHHHHHHHHHHCCCCCCEEEEEECCC
SQHSSIALGDTLGSNIVNVSFILAVALLISPISVSKSTTQRDFTLALFVPIVSAVLLLDN
CCCCCEEECHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ELSRFDGAILLTLFIGWLIAAIVEAKKDRKKTLHQENVQTLRKYVLPTLIGLVMLFAAGN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FIVTSATTIAKSFGVNDFLIGATIVALGTSVPELASTIMAKIRGHNDMSLGTILGSNIFN
EEEEHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
GLLIVATAALLNPITITFQEVLPTIAFGIAVLLFSYPYRNNTITRLQGGLLLMLYFAYLG
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCHHHHHHHHHHHH
VMIWTQT
HHHHCCC
>Mature Secondary Structure
MEYLLLLLGIACAAFGGELFIRGAVGIAYAARIKPAIIGVTIAAFATSSPELSIAINAGA
CHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHCHHHHHHHHHHHCCCCCCEEEEEECCC
SQHSSIALGDTLGSNIVNVSFILAVALLISPISVSKSTTQRDFTLALFVPIVSAVLLLDN
CCCCCEEECHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ELSRFDGAILLTLFIGWLIAAIVEAKKDRKKTLHQENVQTLRKYVLPTLIGLVMLFAAGN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FIVTSATTIAKSFGVNDFLIGATIVALGTSVPELASTIMAKIRGHNDMSLGTILGSNIFN
EEEEHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
GLLIVATAALLNPITITFQEVLPTIAFGIAVLLFSYPYRNNTITRLQGGLLLMLYFAYLG
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCHHHHHHHHHHHH
VMIWTQT
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; Ca (II) [Cytoplasm] [C]

Specific reaction: Na (I) [Periplasm] + Ca (II) [Cytoplasm] = Na (I) [Cytoplasm] + Ca (II) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]