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The map label for this gene is aspS

Identifier: 78188900

GI number: 78188900

Start: 1266950

End: 1268767

Strand: Reverse

Name: aspS

Synonym: Cag_0932

Alternate gene names: 78188900

Gene position: 1268767-1266950 (Counterclockwise)

Preceding gene: 78188901

Following gene: 78188889

Centisome position: 49.33

GC content: 46.09

Gene sequence:

>1818_bases
ATGAGTAATCCTGTTGAGCAGCAAGTGGTTTGCAACCGTTTTCGTTCTCACTCTTGTGGGCTATTAAATGCCACGTTTGA
ACAACAGCACGTGCGCTTAGCTGGCTGGGTCCACAGAAAACGCGACCATGGTGGGCTTATTTTTATTGATTTACGCGACC
ATACGGGTATTTGCCAGCTCGTTATTCAACCCGAACAGCAAGCGCTTTTTGCGGAAGCTGAACATCTCCATAATGAATCA
GTTATTAGCGTTGAAGGCACCGTTATTCTTCGTGCTGAAAATGCCATCAATCCACGCCTTTCATCGGGCGAAATAGAGGT
AGTGATAAGCTGCATGAGCATTGAAAGCAATGCCCATCCACTTCCATTTTCCGTTGCGGATGAACTTCCCACCTCCGAAG
AGCTTCGCCTGAAATATCGCTTTCTTGATTTACGCCGCGAAAAGCTACATGAGAACATCATTTTCCGTAGCCGCTTAACG
GCGGCTGTTCGGCGCTATTTGGAGGAAAAGAATTTCACGGAAATTCAAACCCCAATTTTAACCTCCAGCTCACCTGAAGG
TGCTCGCGACTTTTTGGTACCAAGCCGCTTGCATCCGGGAAAATTTTACGCTCTTCCACAAGCACCTCAGCAATTTAAAC
AGCTTTTAATGGTGGCAGGATTTCCACGCTACTTCCAAATTGCACCATGTTTTCGTGATGAGGATGCACGTGCTGACCGC
AGTCCGGGCGAATTTTACCAGCTTGATATGGAGATGGCTTTTATTGAGCAGGAAAATTTGTTTGAGATTTTGGAAGGAAT
GCTGGAGCACATTACAAGCACCATGTCGAAAAAGCGCATCACGCAAGTGCCTTTTCCTCGCATTAGCTACCGCGATGTCA
TGAACCGCTTTGGCACCGATAAGCCCGATTTACGCATTCCGCTTGAAATTCAAGATGTTACCTCACTCTTTGTGGATTCA
GGCTTTAAAGTGTTTGCAAAAAACACCGTGCCCGGTTGCTGCGTAAAGGCGTTGGTAGTAAAGGGACGTGGCAATGAATC
GCGCTTGTTTTACGATAAAGCTGAAAAACGAGCAAAAGAGCTTGGCTCTGCAGGACTTGCTTACATTCAATTTAAAGATG
AAGGGGCAAAAGGTCCGCTTGTAAAGTTCCTTTCTGAGGATGATATGAATGCCTTAAAGCAGCACCTTAACCTTGAGCAA
GGTGATGTTGTCTTTTTTGGAGCAGGCAAATGGGAAGTTACCTGCAAAATTATGGGCGGAATGCGCAACTACTTTGCCGA
TCTTTTTACGCTTGATAAGGATGAGCTCTCCTTTTGCTGGATTGTTGATTTCCCCATGTACGAGTACAATGAAGAGGCAA
AGAAAATTGACTTTTCACACAACCCATTTTCCATGCCACAAGGCGAAATGGAGGCACTTGAAACCAAAGATGCTCTCGAT
ATTTTAGCCTATCAATACGACATTGTGTGTAACGGCATTGAGCTTTCGAGCGGTGCTATCCGCAACCACAAGCCGGAAAT
TATGTACAAAGCCTTTGCAATTGCGGGCTATAGCCGCGAAGAGGTTGACCAGCGCTTTGGGCACATGATTGAAGCCTTTA
AGCTTGGCGCTCCACCGCACGGTGGCATTGCACCAGGGCTTGATCGTTTGGTAATGATTTTATGCGATGAGCAAAACATC
CGTGAGGTTATTGCCTTCCCTATGAACCAACAAGCCCAAGATTTAATGATGTCGGCTCCATCAGAAGTTACCTTAGCGCA
GCTCCGTGAGTTGCACTTAAAAGTGGAGTTGCCAAAGAAAGAGGAGAAGAAAGGGTAG

Upstream 100 bases:

>100_bases
TCATATTCCGTGCCATTGTAGCTTGCATCTTTATCTAACCGATAAAATGTAAGTAAGAGCATTAAAAAATTATTTCCAAT
TATCTATAGAAAGGCGCTTT

Downstream 100 bases:

>100_bases
GGGAGATATATCGCTGTTTTTTCGGATTCAATATTTTTTAAACGGGCGCTCCATAGAGGGTGCCCGTTGTGTTTAAAGGT
GGTACGGCAACCAAACCAGA

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS

Number of amino acids: Translated: 605; Mature: 604

Protein sequence:

>605_residues
MSNPVEQQVVCNRFRSHSCGLLNATFEQQHVRLAGWVHRKRDHGGLIFIDLRDHTGICQLVIQPEQQALFAEAEHLHNES
VISVEGTVILRAENAINPRLSSGEIEVVISCMSIESNAHPLPFSVADELPTSEELRLKYRFLDLRREKLHENIIFRSRLT
AAVRRYLEEKNFTEIQTPILTSSSPEGARDFLVPSRLHPGKFYALPQAPQQFKQLLMVAGFPRYFQIAPCFRDEDARADR
SPGEFYQLDMEMAFIEQENLFEILEGMLEHITSTMSKKRITQVPFPRISYRDVMNRFGTDKPDLRIPLEIQDVTSLFVDS
GFKVFAKNTVPGCCVKALVVKGRGNESRLFYDKAEKRAKELGSAGLAYIQFKDEGAKGPLVKFLSEDDMNALKQHLNLEQ
GDVVFFGAGKWEVTCKIMGGMRNYFADLFTLDKDELSFCWIVDFPMYEYNEEAKKIDFSHNPFSMPQGEMEALETKDALD
ILAYQYDIVCNGIELSSGAIRNHKPEIMYKAFAIAGYSREEVDQRFGHMIEAFKLGAPPHGGIAPGLDRLVMILCDEQNI
REVIAFPMNQQAQDLMMSAPSEVTLAQLRELHLKVELPKKEEKKG

Sequences:

>Translated_605_residues
MSNPVEQQVVCNRFRSHSCGLLNATFEQQHVRLAGWVHRKRDHGGLIFIDLRDHTGICQLVIQPEQQALFAEAEHLHNES
VISVEGTVILRAENAINPRLSSGEIEVVISCMSIESNAHPLPFSVADELPTSEELRLKYRFLDLRREKLHENIIFRSRLT
AAVRRYLEEKNFTEIQTPILTSSSPEGARDFLVPSRLHPGKFYALPQAPQQFKQLLMVAGFPRYFQIAPCFRDEDARADR
SPGEFYQLDMEMAFIEQENLFEILEGMLEHITSTMSKKRITQVPFPRISYRDVMNRFGTDKPDLRIPLEIQDVTSLFVDS
GFKVFAKNTVPGCCVKALVVKGRGNESRLFYDKAEKRAKELGSAGLAYIQFKDEGAKGPLVKFLSEDDMNALKQHLNLEQ
GDVVFFGAGKWEVTCKIMGGMRNYFADLFTLDKDELSFCWIVDFPMYEYNEEAKKIDFSHNPFSMPQGEMEALETKDALD
ILAYQYDIVCNGIELSSGAIRNHKPEIMYKAFAIAGYSREEVDQRFGHMIEAFKLGAPPHGGIAPGLDRLVMILCDEQNI
REVIAFPMNQQAQDLMMSAPSEVTLAQLRELHLKVELPKKEEKKG
>Mature_604_residues
SNPVEQQVVCNRFRSHSCGLLNATFEQQHVRLAGWVHRKRDHGGLIFIDLRDHTGICQLVIQPEQQALFAEAEHLHNESV
ISVEGTVILRAENAINPRLSSGEIEVVISCMSIESNAHPLPFSVADELPTSEELRLKYRFLDLRREKLHENIIFRSRLTA
AVRRYLEEKNFTEIQTPILTSSSPEGARDFLVPSRLHPGKFYALPQAPQQFKQLLMVAGFPRYFQIAPCFRDEDARADRS
PGEFYQLDMEMAFIEQENLFEILEGMLEHITSTMSKKRITQVPFPRISYRDVMNRFGTDKPDLRIPLEIQDVTSLFVDSG
FKVFAKNTVPGCCVKALVVKGRGNESRLFYDKAEKRAKELGSAGLAYIQFKDEGAKGPLVKFLSEDDMNALKQHLNLEQG
DVVFFGAGKWEVTCKIMGGMRNYFADLFTLDKDELSFCWIVDFPMYEYNEEAKKIDFSHNPFSMPQGEMEALETKDALDI
LAYQYDIVCNGIELSSGAIRNHKPEIMYKAFAIAGYSREEVDQRFGHMIEAFKLGAPPHGGIAPGLDRLVMILCDEQNIR
EVIAFPMNQQAQDLMMSAPSEVTLAQLRELHLKVELPKKEEKKG

Specific function: Unknown

COG id: COG0173

COG function: function code J; Aspartyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI40789249, Length=606, Percent_Identity=35.973597359736, Blast_Score=362, Evalue=1e-100,
Organism=Homo sapiens, GI45439306, Length=240, Percent_Identity=29.1666666666667, Blast_Score=90, Evalue=8e-18,
Organism=Homo sapiens, GI5031815, Length=258, Percent_Identity=29.0697674418605, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI226491502, Length=270, Percent_Identity=25.1851851851852, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI194272210, Length=258, Percent_Identity=29.0697674418605, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI4758762, Length=286, Percent_Identity=24.4755244755245, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI1788173, Length=590, Percent_Identity=41.3559322033898, Blast_Score=447, Evalue=1e-127,
Organism=Escherichia coli, GI1790571, Length=317, Percent_Identity=24.2902208201893, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1789256, Length=333, Percent_Identity=25.2252252252252, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI32566633, Length=598, Percent_Identity=33.2775919732441, Blast_Score=297, Evalue=1e-80,
Organism=Caenorhabditis elegans, GI17551876, Length=289, Percent_Identity=25.6055363321799, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71994340, Length=252, Percent_Identity=23.8095238095238, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17535927, Length=252, Percent_Identity=23.8095238095238, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17535925, Length=252, Percent_Identity=23.8095238095238, Blast_Score=75, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6325153, Length=303, Percent_Identity=37.2937293729373, Blast_Score=165, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6323011, Length=287, Percent_Identity=30.6620209059233, Blast_Score=93, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6321807, Length=286, Percent_Identity=24.8251748251748, Blast_Score=87, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6320242, Length=330, Percent_Identity=24.5454545454545, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24584738, Length=605, Percent_Identity=34.2148760330578, Blast_Score=320, Evalue=1e-87,
Organism=Drosophila melanogaster, GI17136276, Length=275, Percent_Identity=27.6363636363636, Blast_Score=81, Evalue=3e-15,
Organism=Drosophila melanogaster, GI19921528, Length=284, Percent_Identity=26.4084507042254, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24640849, Length=289, Percent_Identity=24.5674740484429, Blast_Score=65, Evalue=1e-10,

Paralogues:

None

Copy number: 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYD_CHLCH (Q3AS30)

Other databases:

- EMBL:   CP000108
- RefSeq:   YP_379238.1
- ProteinModelPortal:   Q3AS30
- SMR:   Q3AS30
- STRING:   Q3AS30
- GeneID:   3747085
- GenomeReviews:   CP000108_GR
- KEGG:   cch:Cag_0932
- eggNOG:   COG0173
- HOGENOM:   HBG396032
- OMA:   YQLDVEM
- ProtClustDB:   PRK00476
- BioCyc:   CCHL340177:CAG_0932-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00044_B
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020564
- InterPro:   IPR004524
- InterPro:   IPR018153
- InterPro:   IPR002312
- InterPro:   IPR004115
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:3.30.1360.30
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PANTHER:   PTHR22594:SF5
- PRINTS:   PR01042
- TIGRFAMs:   TIGR00459

Pfam domain/function: PF02938 GAD; PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.12

Molecular weight: Translated: 68900; Mature: 68769

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNPVEQQVVCNRFRSHSCGLLNATFEQQHVRLAGWVHRKRDHGGLIFIDLRDHTGICQL
CCCCHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEE
VIQPEQQALFAEAEHLHNESVISVEGTVILRAENAINPRLSSGEIEVVISCMSIESNAHP
EECCCHHHHHHHHHHCCCCCEEEECCEEEEEECCCCCCCCCCCCEEEEEEEEEECCCCCC
LPFSVADELPTSEELRLKYRFLDLRREKLHENIIFRSRLTAAVRRYLEEKNFTEIQTPIL
CCCHHHHCCCCCHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
TSSSPEGARDFLVPSRLHPGKFYALPQAPQQFKQLLMVAGFPRYFQIAPCFRDEDARADR
CCCCCCCCHHCCCCCCCCCCCEEECCCCHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCC
SPGEFYQLDMEMAFIEQENLFEILEGMLEHITSTMSKKRITQVPFPRISYRDVMNRFGTD
CCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCC
KPDLRIPLEIQDVTSLFVDSGFKVFAKNTVPGCCVKALVVKGRGNESRLFYDKAEKRAKE
CCCEEEEEEHHHHHHHHHCCCCEEEECCCCCHHHHHHHHEECCCCCCEEEHHHHHHHHHH
LGSAGLAYIQFKDEGAKGPLVKFLSEDDMNALKQHLNLEQGDVVFFGAGKWEVTCKIMGG
HCCCCEEEEEEECCCCCCCHHHHHCCCCHHHHHHHCCCCCCCEEEEECCCEEEEEEEHHH
MRNYFADLFTLDKDELSFCWIVDFPMYEYNEEAKKIDFSHNPFSMPQGEMEALETKDALD
HHHHHHHHHCCCCCCCCEEEEEECCCHHCCCHHHEECCCCCCCCCCCCHHHHHHHHHHHH
ILAYQYDIVCNGIELSSGAIRNHKPEIMYKAFAIAGYSREEVDQRFGHMIEAFKLGAPPH
HHHEEEEEEECCEEECCCCCCCCCCHHEEEEHHHCCCCHHHHHHHHHHHHHHHHCCCCCC
GGIAPGLDRLVMILCDEQNIREVIAFPMNQQAQDLMMSAPSEVTLAQLRELHLKVELPKK
CCCCCCHHHEEEEEECCCCHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHEEEEECCCH
EEKKG
HCCCC
>Mature Secondary Structure 
SNPVEQQVVCNRFRSHSCGLLNATFEQQHVRLAGWVHRKRDHGGLIFIDLRDHTGICQL
CCCHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEE
VIQPEQQALFAEAEHLHNESVISVEGTVILRAENAINPRLSSGEIEVVISCMSIESNAHP
EECCCHHHHHHHHHHCCCCCEEEECCEEEEEECCCCCCCCCCCCEEEEEEEEEECCCCCC
LPFSVADELPTSEELRLKYRFLDLRREKLHENIIFRSRLTAAVRRYLEEKNFTEIQTPIL
CCCHHHHCCCCCHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
TSSSPEGARDFLVPSRLHPGKFYALPQAPQQFKQLLMVAGFPRYFQIAPCFRDEDARADR
CCCCCCCCHHCCCCCCCCCCCEEECCCCHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCC
SPGEFYQLDMEMAFIEQENLFEILEGMLEHITSTMSKKRITQVPFPRISYRDVMNRFGTD
CCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCC
KPDLRIPLEIQDVTSLFVDSGFKVFAKNTVPGCCVKALVVKGRGNESRLFYDKAEKRAKE
CCCEEEEEEHHHHHHHHHCCCCEEEECCCCCHHHHHHHHEECCCCCCEEEHHHHHHHHHH
LGSAGLAYIQFKDEGAKGPLVKFLSEDDMNALKQHLNLEQGDVVFFGAGKWEVTCKIMGG
HCCCCEEEEEEECCCCCCCHHHHHCCCCHHHHHHHCCCCCCCEEEEECCCEEEEEEEHHH
MRNYFADLFTLDKDELSFCWIVDFPMYEYNEEAKKIDFSHNPFSMPQGEMEALETKDALD
HHHHHHHHHCCCCCCCCEEEEEECCCHHCCCHHHEECCCCCCCCCCCCHHHHHHHHHHHH
ILAYQYDIVCNGIELSSGAIRNHKPEIMYKAFAIAGYSREEVDQRFGHMIEAFKLGAPPH
HHHEEEEEEECCEEECCCCCCCCCCHHEEEEHHHCCCCHHHHHHHHHHHHHHHHCCCCCC
GGIAPGLDRLVMILCDEQNIREVIAFPMNQQAQDLMMSAPSEVTLAQLRELHLKVELPKK
CCCCCCHHHEEEEEECCCCHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHEEEEECCCH
EEKKG
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA