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The map label for this gene is cobU [H]

Identifier: 78188816

GI number: 78188816

Start: 1177160

End: 1177690

Strand: Reverse

Name: cobU [H]

Synonym: Cag_0846

Alternate gene names: 78188816

Gene position: 1177690-1177160 (Counterclockwise)

Preceding gene: 78188817

Following gene: 78188811

Centisome position: 45.79

GC content: 47.65

Gene sequence:

>531_bases
ATGAAAAAGATCATTTACGTTACAGGAGGCGCACGAAGCGGCAAAAGCTCCTTTGCACTCCAACAAGCCCTTACCTATCA
AAACCGCGTTTTTTTAGCAACCGCCGAACCATTTGATGACGAAATGCGCCAACGCATTAGCAAACATCAGCAAGAACGAT
TAGAACATTTTACCACCATTGAAGAGCCATTAAACCTTGAACAAGCATTAAAGATGCTGCCCTCAGATACGGAGGTGGTG
CTTCTGGACTGCCTTACCGTATGGACGGGTAACCTTATGCACCACCTTGGAACGGAGAGTGCAGACGGTGAAAAAGCTAT
TGAAGAAAAACTTCAGCAACTGCTCGATGTATTGCGCCAACCACCTTGTACCATCATTCTTGTTTCCAACGAAGTTGGTA
TGGGCATTGTGCCCGAAAACCGCATGGCACGCCACTTTCGCGATCTTGCAGGCACTATTAATCAGCGCGTGGCTGCCATA
GCTACTGAGGCTTGGCTGCTTTGCAGTGGTTTGCCGATACGGTTGAAATAG

Upstream 100 bases:

>100_bases
CGCCCTTGCTCGTTACGAAGCAAACTTGTAGCTCAGCAGTAGGGGAGAGCCTCTCTTTTTTTACAGGGGAACAATTCCCG
TGAACAGGAAATAATGCAAC

Downstream 100 bases:

>100_bases
GTGGAATGGGGGAGCAATCAAAAAACCTTACATTTTTTGCATTTCATCAAGTAAATCAGGATGCCGATCTATCAATTTCA
ACAATTTGACTAACGGTGCT

Product: cobalamin biosynthesis protein CobP

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MKKIIYVTGGARSGKSSFALQQALTYQNRVFLATAEPFDDEMRQRISKHQQERLEHFTTIEEPLNLEQALKMLPSDTEVV
LLDCLTVWTGNLMHHLGTESADGEKAIEEKLQQLLDVLRQPPCTIILVSNEVGMGIVPENRMARHFRDLAGTINQRVAAI
ATEAWLLCSGLPIRLK

Sequences:

>Translated_176_residues
MKKIIYVTGGARSGKSSFALQQALTYQNRVFLATAEPFDDEMRQRISKHQQERLEHFTTIEEPLNLEQALKMLPSDTEVV
LLDCLTVWTGNLMHHLGTESADGEKAIEEKLQQLLDVLRQPPCTIILVSNEVGMGIVPENRMARHFRDLAGTINQRVAAI
ATEAWLLCSGLPIRLK
>Mature_176_residues
MKKIIYVTGGARSGKSSFALQQALTYQNRVFLATAEPFDDEMRQRISKHQQERLEHFTTIEEPLNLEQALKMLPSDTEVV
LLDCLTVWTGNLMHHLGTESADGEKAIEEKLQQLLDVLRQPPCTIILVSNEVGMGIVPENRMARHFRDLAGTINQRVAAI
ATEAWLLCSGLPIRLK

Specific function: ATP-dependent phosphorylation of adenosylcobinamide and adds GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=180, Percent_Identity=42.2222222222222, Blast_Score=146, Evalue=6e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 19809; Mature: 19809

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIIYVTGGARSGKSSFALQQALTYQNRVFLATAEPFDDEMRQRISKHQQERLEHFTTI
CCEEEEEECCCCCCCHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
EEPLNLEQALKMLPSDTEVVLLDCLTVWTGNLMHHLGTESADGEKAIEEKLQQLLDVLRQ
HCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCC
PPCTIILVSNEVGMGIVPENRMARHFRDLAGTINQRVAAIATEAWLLCSGLPIRLK
CCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEC
>Mature Secondary Structure
MKKIIYVTGGARSGKSSFALQQALTYQNRVFLATAEPFDDEMRQRISKHQQERLEHFTTI
CCEEEEEECCCCCCCHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
EEPLNLEQALKMLPSDTEVVLLDCLTVWTGNLMHHLGTESADGEKAIEEKLQQLLDVLRQ
HCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCC
PPCTIILVSNEVGMGIVPENRMARHFRDLAGTINQRVAAIATEAWLLCSGLPIRLK
CCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]