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The map label for this gene is ffh [H]

Identifier: 78188776

GI number: 78188776

Start: 1127792

End: 1129147

Strand: Reverse

Name: ffh [H]

Synonym: Cag_0805

Alternate gene names: 78188776

Gene position: 1129147-1127792 (Counterclockwise)

Preceding gene: 78188782

Following gene: 78188775

Centisome position: 43.9

GC content: 42.63

Gene sequence:

>1356_bases
ATGGCAATGTTTGAAAGTTTAAGTGATAAACTTGAGGCTACTTTTAAAAAATTAGCAGGTCAAGCCACCATCAACGAAAT
TAATATTGGTGTTGCCATGCGCGACATCAAGCGTGCGTTGCTTGCGGCTGACGTGAACTACAAGGTTGCTAAAAAATTAA
TAGAAGATATTCGGGAGAAGTCGCTGGGCGAAGAGGTGATTAAAAGTGTGTCGCCTGCCCAGATGATTGTTAAAATTGTT
TACGATGAACTAACGGAGTTAATGGGTGGCGAGCAAAAGCCGCTGAACCTTTCTCCTAAAAAGTTGCCAGCAATTATTAT
GGTTGCTGGTTTACAAGGTTCAGGTAAAACCACCTTTTGTGCCAAGCTTGCCTTGCGTTTACGCAAAAATGGCAAAAACC
CTATGTTGATTGCGGCTGACGTTTATCGTCCAGCGGCTGTTGACCAGCTTAAAGCGTTGGGTGAGCAAGTTGAAGTACCT
GTTTTTTCGGTTGATGAGAAGGATGCCATGAAGGCAGCGCTTCAAGGGCTTGAAGCCGCTAAGGCAGCCGCTAAAGATGT
TGTTATTGTTGATACGGCTGGTCGTTTGCAAATTGACCAAGCCATGATGGCTGAAGCTGAAGCGTTAAAAAATGCGCTCA
AGCCTGATGAATTGCTGTTTGTTGTTGATTCAATGATGGGTCAAGAAGCCGTTAATACCGCTAAAGCGTTTAACGATCGG
CTTGACTTTGATGGAGTAGTGCTCACCAAACTTGATGGTGATGCGCGAGGTGGTGCGGCGCTTTCAATTCGTCAAGTGGT
TGAAAAGCCAATAAAGTTCATCAGCATTGGTGAAAAGGTTGACGACCTCGATATTTTCTACCCCGATCGTATGGCTCAGA
GAATTCTGGGCATGGGCGATATTATTAGCTTTGTTGAAAAAGCACAAGAAAATCTTGATCTTGACAAAGCGATTGAGATG
CAGAAAAAGTTGATGAAAAATGAGTTCGACTTGAACGACTTTTTTGATCAATTACAGCAACTGAAAAAAATGGGCTCTAT
TCAAGGGCTTATTGAAATGGTGCCGGGTTTAAACAAAATGGTGCCCAAGCAAGAGCTTGAAAATCTTGATTTTAAGCCAA
TTGAGGCAATGATTAGCTCTATGACCAAAGAAGAGCGATCAAACCCTGAAATGATAAATGGTAGCCGTCGCCAACGTATT
GCGCGTGGTAGCGGTCGCAAAGTGCAAGAGGTTAATTTGCTGTTAAAGCAATTTGGGGAAATGAAAAAGATGATGAAAGC
CGTTTCAAAACTCTCCAAATCGGGCAGAAAAATAACGCCACAAAATCTTGCCCTCGATAAATTTTTAAAGCGTTAA

Upstream 100 bases:

>100_bases
ACAAAGCGTAAAGATACTCTTTTGATAATTTTATTTTTAGCTGATTTTTATTATCATTAAAGCTAATCCTTTTTAAGCTT
TACCCCCTGATATAGCGGCT

Downstream 100 bases:

>100_bases
AAGCGCTCTAAGAGCTTCAAAACTTTCTCTATTAACATAAATTATTTGAGCTTTGGTAAAGATCAGACTGAAAAGAGCAG
GCAGAAAAAAAATGCCAGTG

Product: Signal recognition particle protein

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MAMFESLSDKLEATFKKLAGQATINEINIGVAMRDIKRALLAADVNYKVAKKLIEDIREKSLGEEVIKSVSPAQMIVKIV
YDELTELMGGEQKPLNLSPKKLPAIIMVAGLQGSGKTTFCAKLALRLRKNGKNPMLIAADVYRPAAVDQLKALGEQVEVP
VFSVDEKDAMKAALQGLEAAKAAAKDVVIVDTAGRLQIDQAMMAEAEALKNALKPDELLFVVDSMMGQEAVNTAKAFNDR
LDFDGVVLTKLDGDARGGAALSIRQVVEKPIKFISIGEKVDDLDIFYPDRMAQRILGMGDIISFVEKAQENLDLDKAIEM
QKKLMKNEFDLNDFFDQLQQLKKMGSIQGLIEMVPGLNKMVPKQELENLDFKPIEAMISSMTKEERSNPEMINGSRRQRI
ARGSGRKVQEVNLLLKQFGEMKKMMKAVSKLSKSGRKITPQNLALDKFLKR

Sequences:

>Translated_451_residues
MAMFESLSDKLEATFKKLAGQATINEINIGVAMRDIKRALLAADVNYKVAKKLIEDIREKSLGEEVIKSVSPAQMIVKIV
YDELTELMGGEQKPLNLSPKKLPAIIMVAGLQGSGKTTFCAKLALRLRKNGKNPMLIAADVYRPAAVDQLKALGEQVEVP
VFSVDEKDAMKAALQGLEAAKAAAKDVVIVDTAGRLQIDQAMMAEAEALKNALKPDELLFVVDSMMGQEAVNTAKAFNDR
LDFDGVVLTKLDGDARGGAALSIRQVVEKPIKFISIGEKVDDLDIFYPDRMAQRILGMGDIISFVEKAQENLDLDKAIEM
QKKLMKNEFDLNDFFDQLQQLKKMGSIQGLIEMVPGLNKMVPKQELENLDFKPIEAMISSMTKEERSNPEMINGSRRQRI
ARGSGRKVQEVNLLLKQFGEMKKMMKAVSKLSKSGRKITPQNLALDKFLKR
>Mature_450_residues
AMFESLSDKLEATFKKLAGQATINEINIGVAMRDIKRALLAADVNYKVAKKLIEDIREKSLGEEVIKSVSPAQMIVKIVY
DELTELMGGEQKPLNLSPKKLPAIIMVAGLQGSGKTTFCAKLALRLRKNGKNPMLIAADVYRPAAVDQLKALGEQVEVPV
FSVDEKDAMKAALQGLEAAKAAAKDVVIVDTAGRLQIDQAMMAEAEALKNALKPDELLFVVDSMMGQEAVNTAKAFNDRL
DFDGVVLTKLDGDARGGAALSIRQVVEKPIKFISIGEKVDDLDIFYPDRMAQRILGMGDIISFVEKAQENLDLDKAIEMQ
KKLMKNEFDLNDFFDQLQQLKKMGSIQGLIEMVPGLNKMVPKQELENLDFKPIEAMISSMTKEERSNPEMINGSRRQRIA
RGSGRKVQEVNLLLKQFGEMKKMMKAVSKLSKSGRKITPQNLALDKFLKR

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=441, Percent_Identity=34.6938775510204, Blast_Score=240, Evalue=2e-63,
Organism=Homo sapiens, GI226371618, Length=384, Percent_Identity=35.4166666666667, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI89061728, Length=155, Percent_Identity=38.7096774193548, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI23308697, Length=301, Percent_Identity=28.5714285714286, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI295424842, Length=301, Percent_Identity=28.5714285714286, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1788963, Length=430, Percent_Identity=47.6744186046512, Blast_Score=380, Evalue=1e-107,
Organism=Escherichia coli, GI1789874, Length=265, Percent_Identity=33.5849056603774, Blast_Score=150, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17539958, Length=451, Percent_Identity=32.3725055432373, Blast_Score=240, Evalue=1e-63,
Organism=Caenorhabditis elegans, GI193206261, Length=298, Percent_Identity=26.8456375838926, Blast_Score=96, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6325345, Length=416, Percent_Identity=36.5384615384615, Blast_Score=238, Evalue=2e-63,
Organism=Saccharomyces cerevisiae, GI6320498, Length=310, Percent_Identity=22.258064516129, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI17647949, Length=454, Percent_Identity=33.920704845815, Blast_Score=228, Evalue=8e-60,
Organism=Drosophila melanogaster, GI24641198, Length=316, Percent_Identity=28.1645569620253, Blast_Score=108, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 49947; Mature: 49816

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMFESLSDKLEATFKKLAGQATINEINIGVAMRDIKRALLAADVNYKVAKKLIEDIREK
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
SLGEEVIKSVSPAQMIVKIVYDELTELMGGEQKPLNLSPKKLPAIIMVAGLQGSGKTTFC
HHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCEEEEEECCCCCCCHHHH
AKLALRLRKNGKNPMLIAADVYRPAAVDQLKALGEQVEVPVFSVDEKDAMKAALQGLEAA
HHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHH
KAAAKDVVIVDTAGRLQIDQAMMAEAEALKNALKPDELLFVVDSMMGQEAVNTAKAFNDR
HHHHCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
LDFDGVVLTKLDGDARGGAALSIRQVVEKPIKFISIGEKVDDLDIFYPDRMAQRILGMGD
CCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCHHH
IISFVEKAQENLDLDKAIEMQKKLMKNEFDLNDFFDQLQQLKKMGSIQGLIEMVPGLNKM
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHC
VPKQELENLDFKPIEAMISSMTKEERSNPEMINGSRRQRIARGSGRKVQEVNLLLKQFGE
CCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHH
MKKMMKAVSKLSKSGRKITPQNLALDKFLKR
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
AMFESLSDKLEATFKKLAGQATINEINIGVAMRDIKRALLAADVNYKVAKKLIEDIREK
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
SLGEEVIKSVSPAQMIVKIVYDELTELMGGEQKPLNLSPKKLPAIIMVAGLQGSGKTTFC
HHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCEEEEEECCCCCCCHHHH
AKLALRLRKNGKNPMLIAADVYRPAAVDQLKALGEQVEVPVFSVDEKDAMKAALQGLEAA
HHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHH
KAAAKDVVIVDTAGRLQIDQAMMAEAEALKNALKPDELLFVVDSMMGQEAVNTAKAFNDR
HHHHCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
LDFDGVVLTKLDGDARGGAALSIRQVVEKPIKFISIGEKVDDLDIFYPDRMAQRILGMGD
CCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCHHH
IISFVEKAQENLDLDKAIEMQKKLMKNEFDLNDFFDQLQQLKKMGSIQGLIEMVPGLNKM
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHC
VPKQELENLDFKPIEAMISSMTKEERSNPEMINGSRRQRIARGSGRKVQEVNLLLKQFGE
CCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHH
MKKMMKAVSKLSKSGRKITPQNLALDKFLKR
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]