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The map label for this gene is nrfC [H]

Identifier: 78188597

GI number: 78188597

Start: 893187

End: 893729

Strand: Reverse

Name: nrfC [H]

Synonym: Cag_0619

Alternate gene names: 78188597

Gene position: 893729-893187 (Counterclockwise)

Preceding gene: 78188598

Following gene: 78188596

Centisome position: 34.75

GC content: 50.09

Gene sequence:

>543_bases
ATGATTATTGATACCCGCGTTTGCGTTGGCTGTTCAGCCTGTGTTTACGCTTGTAAATCGGAAAACGAAGTGCCCGTTGG
CTACTGCCGCGATTGGGTTGTGCAAGAAACCAACGGCAACTTCCCCAAACTCAGCATGGAAAACCGCTCAGAACGCTGCC
AACATTGTGATAACGCCCCATGCGTTACCTACTGCCCAACAGGCGCTTCGCATTACGACGAGTTTGGCACGGTGCAAATT
AACCGTTCGCGCTGCACGGGATGTAAAGCCTGCATGGCAGCCTGCCCTTATGATGCACGCTACGTTCACCCTGATGGTTT
TGTTGACAAATGTACCCTTTGCCACCACCGCCTTGAGAAGGGAATGAAAACCGCATGTGTTTCCATTTGCCCAACAGGTA
GCTTGCATTTGGTCAATTTTGCAAACCTTACCGCTGACGACAAAGCTATGATGGCAGGTAAAGAGGTTTATCGCCAAAAA
GCACATGCTGGCACAGAGCCACGACTTTACTGGATTTCCGCAAGTAATAAACCCGGAGCGTAA

Upstream 100 bases:

>100_bases
CCGTTGATATTGATATGGCAATGGGCGGCGTTGGCTTTCAAAACAACTTTGTAACCTTTGTTAAGGAGGCATCAGCTTGA
GTACAAAGAAAAATTACGGG

Downstream 100 bases:

>100_bases
CTATGATTGACGGCACTCGTGAACTCATTTCCACGAAACTTAATCCGCAGGTTTTACCGCACCTGCACATTTGGGAGTGG
CACATTCCGCTCTACCTTTT

Product: NrfC protein

Products: oxidized cytochrome C552; NH3 [C]

Alternate protein names: NA

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MIIDTRVCVGCSACVYACKSENEVPVGYCRDWVVQETNGNFPKLSMENRSERCQHCDNAPCVTYCPTGASHYDEFGTVQI
NRSRCTGCKACMAACPYDARYVHPDGFVDKCTLCHHRLEKGMKTACVSICPTGSLHLVNFANLTADDKAMMAGKEVYRQK
AHAGTEPRLYWISASNKPGA

Sequences:

>Translated_180_residues
MIIDTRVCVGCSACVYACKSENEVPVGYCRDWVVQETNGNFPKLSMENRSERCQHCDNAPCVTYCPTGASHYDEFGTVQI
NRSRCTGCKACMAACPYDARYVHPDGFVDKCTLCHHRLEKGMKTACVSICPTGSLHLVNFANLTADDKAMMAGKEVYRQK
AHAGTEPRLYWISASNKPGA
>Mature_180_residues
MIIDTRVCVGCSACVYACKSENEVPVGYCRDWVVQETNGNFPKLSMENRSERCQHCDNAPCVTYCPTGASHYDEFGTVQI
NRSRCTGCKACMAACPYDARYVHPDGFVDKCTLCHHRLEKGMKTACVSICPTGSLHLVNFANLTADDKAMMAGKEVYRQK
AHAGTEPRLYWISASNKPGA

Specific function: Probably involved in the transfer of electrons from the quinone pool to the type-c cytochromes [H]

COG id: COG0437

COG function: function code C; Fe-S-cluster-containing hydrogenase components 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI2367345, Length=176, Percent_Identity=40.9090909090909, Blast_Score=137, Evalue=3e-34,
Organism=Escherichia coli, GI226510944, Length=173, Percent_Identity=35.8381502890173, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1787749, Length=189, Percent_Identity=33.8624338624339, Blast_Score=86, Evalue=1e-18,
Organism=Escherichia coli, GI1789370, Length=182, Percent_Identity=31.8681318681319, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1790326, Length=155, Percent_Identity=35.4838709677419, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1787872, Length=163, Percent_Identity=33.1288343558282, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787122, Length=148, Percent_Identity=35.1351351351351, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI87082180, Length=163, Percent_Identity=31.9018404907975, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI87082179, Length=155, Percent_Identity=33.5483870967742, Blast_Score=71, Evalue=3e-14,
Organism=Escherichia coli, GI1788811, Length=163, Percent_Identity=30.6748466257669, Blast_Score=69, Evalue=1e-13,
Organism=Escherichia coli, GI1787740, Length=114, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=5e-13,
Organism=Escherichia coli, GI2367245, Length=149, Percent_Identity=32.8859060402685, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1789067, Length=168, Percent_Identity=32.1428571428571, Blast_Score=64, Evalue=4e-12,
Organism=Escherichia coli, GI1787478, Length=121, Percent_Identity=31.404958677686, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1789079, Length=183, Percent_Identity=27.8688524590164, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR017567
- InterPro:   IPR006311 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 19862; Mature: 19862

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

9.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
12.8 %Cys+Met (Translated Protein)
9.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
12.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIDTRVCVGCSACVYACKSENEVPVGYCRDWVVQETNGNFPKLSMENRSERCQHCDNAP
CEECCHHHHHHHHHHHHHCCCCCCCHHHHCCEEEECCCCCCCEECCCCHHHHHHHCCCCC
CVTYCPTGASHYDEFGTVQINRSRCTGCKACMAACPYDARYVHPDGFVDKCTLCHHRLEK
EEEECCCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHH
GMKTACVSICPTGSLHLVNFANLTADDKAMMAGKEVYRQKAHAGTEPRLYWISASNKPGA
HHHHHHHEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MIIDTRVCVGCSACVYACKSENEVPVGYCRDWVVQETNGNFPKLSMENRSERCQHCDNAP
CEECCHHHHHHHHHHHHHCCCCCCCHHHHCCEEEECCCCCCCEECCCCHHHHHHHCCCCC
CVTYCPTGASHYDEFGTVQINRSRCTGCKACMAACPYDARYVHPDGFVDKCTLCHHRLEK
EEEECCCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHH
GMKTACVSICPTGSLHLVNFANLTADDKAMMAGKEVYRQKAHAGTEPRLYWISASNKPGA
HHHHHHHEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: reduced cytochrome C552; nitrite [C]

Specific reaction: reduced cytochrome C552 + nitrite = oxidized cytochrome C552 + NH3 [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]