Click here to switch to the map view.

The map label for this gene is fbp

Identifier: 78188580

GI number: 78188580

Start: 704964

End: 705965

Strand: Reverse

Name: fbp

Synonym: Cag_0602

Alternate gene names: 78188580

Gene position: 705965-704964 (Counterclockwise)

Preceding gene: 78188582

Following gene: 78188579

Centisome position: 27.45

GC content: 47.8

Gene sequence:

>1002_bases
ATGAGCAATCTCATTACCATTGAACGCCACATTCTTGAACAGCAAAAATTTTTTCCTGAAGCACATGGCGAACTAACCGA
CCTGCTTACCGATGTTGCCTTTGCCGCAAAACTTGTTCGCCGCGAAGTGGTACGTGCAGGATTGGTGGACATTCTTGGCT
TAGCAGGCTCCACCAACGTACAAGGCGAAGAGGTAAAAAAACTTGATCTCTTTGCAAACGAACAAATTATTTCTGCAATT
GGCGCTCACGGACGTTTTGCCGTTATGGGTTCCGAAGAGAATGAAGAGATTATTATTCCTACCAACAACGAAAGCGGCAA
CTATGTACTGCTTTTTGATCCGCTTGATGGCTCTTCAAATATTGATGTAAACGTAAGCGTTGGCACCATTTTCTCCATTT
ACAAACTCAAAACCAGCGATCCCGCCAAAGCAAGCCTTGCCGATTGCTTGCAAGCAGGTTCCGAGCAAGTTGCCGCAGGT
TACGTGATTTACGGCTCATCGGTGGTAATGGTTTACACCACAGGACACGGCGTTCATGGCTTTACGTATGACCCAACGAT
TGGCGAATTTTTGCTTTCAGACGAAAACATTACCACACCAAAGCGCGGCAAATATTATTCCATGAACGAAGGCTCCTACG
CTCAGTTTAACGAAGGCACCAAGCGCTACCTCGACTACATTAAAACAGAGGATAAAGCGACTAATCGCCCATACAGCACG
CGCTACATTGGCTCACTTGTGGCTGACTTCCACCGCAACTTGCTGACGGGCGGCATTTTTATTTATCCCCCAACCGGCAA
ACATCCAAACGGCAAGCTACGCCTTATGTACGAAGCCAATCCACTTGCCTTTATTTGCGAACAAGCAGGCGGACGCGCCA
CCAACGGCAAAGAGCGCATTCTCGACATCAAGCCAACCGAACTGCACCAGCGCACGCCACTCTACATTGGCAGCACAGAT
GATGTAATGGTAGCTGAAGAGTTTGAGCAAGGGAAAAGGTAG

Upstream 100 bases:

>100_bases
TCCAACGATATCGTTTCATAATCAAGCAACAAAAGTTTTCTTACATTGAGAGCGTCTCTAAAAAATAGCTCCATTCATAA
CCATAAAGAAAACAAATAAT

Downstream 100 bases:

>100_bases
TAGTTATGAATGTTGGATGTTGTTTTCCGCAATCGGGATTTTCAAGATGAAGGGATATTTTACGCGGGGGCAAACCTATG
TGTTTGCCCTTCGTAATAAC

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MSNLITIERHILEQQKFFPEAHGELTDLLTDVAFAAKLVRREVVRAGLVDILGLAGSTNVQGEEVKKLDLFANEQIISAI
GAHGRFAVMGSEENEEIIIPTNNESGNYVLLFDPLDGSSNIDVNVSVGTIFSIYKLKTSDPAKASLADCLQAGSEQVAAG
YVIYGSSVVMVYTTGHGVHGFTYDPTIGEFLLSDENITTPKRGKYYSMNEGSYAQFNEGTKRYLDYIKTEDKATNRPYST
RYIGSLVADFHRNLLTGGIFIYPPTGKHPNGKLRLMYEANPLAFICEQAGGRATNGKERILDIKPTELHQRTPLYIGSTD
DVMVAEEFEQGKR

Sequences:

>Translated_333_residues
MSNLITIERHILEQQKFFPEAHGELTDLLTDVAFAAKLVRREVVRAGLVDILGLAGSTNVQGEEVKKLDLFANEQIISAI
GAHGRFAVMGSEENEEIIIPTNNESGNYVLLFDPLDGSSNIDVNVSVGTIFSIYKLKTSDPAKASLADCLQAGSEQVAAG
YVIYGSSVVMVYTTGHGVHGFTYDPTIGEFLLSDENITTPKRGKYYSMNEGSYAQFNEGTKRYLDYIKTEDKATNRPYST
RYIGSLVADFHRNLLTGGIFIYPPTGKHPNGKLRLMYEANPLAFICEQAGGRATNGKERILDIKPTELHQRTPLYIGSTD
DVMVAEEFEQGKR
>Mature_332_residues
SNLITIERHILEQQKFFPEAHGELTDLLTDVAFAAKLVRREVVRAGLVDILGLAGSTNVQGEEVKKLDLFANEQIISAIG
AHGRFAVMGSEENEEIIIPTNNESGNYVLLFDPLDGSSNIDVNVSVGTIFSIYKLKTSDPAKASLADCLQAGSEQVAAGY
VIYGSSVVMVYTTGHGVHGFTYDPTIGEFLLSDENITTPKRGKYYSMNEGSYAQFNEGTKRYLDYIKTEDKATNRPYSTR
YIGSLVADFHRNLLTGGIFIYPPTGKHPNGKLRLMYEANPLAFICEQAGGRATNGKERILDIKPTELHQRTPLYIGSTDD
VMVAEEFEQGKR

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family

Homologues:

Organism=Homo sapiens, GI22907028, Length=321, Percent_Identity=45.7943925233645, Blast_Score=283, Evalue=1e-76,
Organism=Homo sapiens, GI189083692, Length=322, Percent_Identity=45.9627329192547, Blast_Score=281, Evalue=7e-76,
Organism=Homo sapiens, GI16579888, Length=322, Percent_Identity=45.9627329192547, Blast_Score=281, Evalue=7e-76,
Organism=Escherichia coli, GI1790679, Length=323, Percent_Identity=56.3467492260062, Blast_Score=378, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI17508131, Length=326, Percent_Identity=50.920245398773, Blast_Score=331, Evalue=4e-91,
Organism=Saccharomyces cerevisiae, GI6323409, Length=324, Percent_Identity=45.0617283950617, Blast_Score=288, Evalue=1e-78,
Organism=Drosophila melanogaster, GI45550998, Length=321, Percent_Identity=47.6635514018692, Blast_Score=302, Evalue=2e-82,
Organism=Drosophila melanogaster, GI19921562, Length=321, Percent_Identity=47.6635514018692, Blast_Score=301, Evalue=3e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): F16PA_CHLCH (Q3AT00)

Other databases:

- EMBL:   CP000108
- RefSeq:   YP_378918.1
- HSSP:   P0A993
- ProteinModelPortal:   Q3AT00
- SMR:   Q3AT00
- STRING:   Q3AT00
- GeneID:   3746295
- GenomeReviews:   CP000108_GR
- KEGG:   cch:Cag_0602
- eggNOG:   COG0158
- HOGENOM:   HBG731261
- OMA:   TCLLVSE
- ProtClustDB:   PRK09293
- BioCyc:   CCHL340177:CAG_0602-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01855
- InterPro:   IPR000146
- PANTHER:   PTHR11556
- PRINTS:   PR00115

Pfam domain/function: PF00316 FBPase

EC number: =3.1.3.11

Molecular weight: Translated: 36720; Mature: 36589

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS00124 FBPASE

Important sites: BINDING 209-209 BINDING 242-242 BINDING 272-272

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNLITIERHILEQQKFFPEAHGELTDLLTDVAFAAKLVRREVVRAGLVDILGLAGSTNV
CCCEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
QGEEVKKLDLFANEQIISAIGAHGRFAVMGSEENEEIIIPTNNESGNYVLLFDPLDGSSN
CHHHHHEEHHHCCHHHHHHHCCCCEEEEECCCCCCEEEEECCCCCCCEEEEEECCCCCCC
IDVNVSVGTIFSIYKLKTSDPAKASLADCLQAGSEQVAAGYVIYGSSVVMVYTTGHGVHG
EEEEEEHHEEEEEEEECCCCCCHHHHHHHHHCCCCHHEEEEEEECCCEEEEEEECCCCCC
FTYDPTIGEFLLSDENITTPKRGKYYSMNEGSYAQFNEGTKRYLDYIKTEDKATNRPYST
EEECCCHHHHEECCCCCCCCCCCCEEECCCCCCHHCCCCHHHHHHHHHCCCCCCCCCCCH
RYIGSLVADFHRNLLTGGIFIYPPTGKHPNGKLRLMYEANPLAFICEQAGGRATNGKERI
HHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEEECCCCEEEEECCCCCCCCCCCEE
LDIKPTELHQRTPLYIGSTDDVMVAEEFEQGKR
EECCCHHHHCCCCEEECCCCCEEEHHHHHCCCC
>Mature Secondary Structure 
SNLITIERHILEQQKFFPEAHGELTDLLTDVAFAAKLVRREVVRAGLVDILGLAGSTNV
CCEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
QGEEVKKLDLFANEQIISAIGAHGRFAVMGSEENEEIIIPTNNESGNYVLLFDPLDGSSN
CHHHHHEEHHHCCHHHHHHHCCCCEEEEECCCCCCEEEEECCCCCCCEEEEEECCCCCCC
IDVNVSVGTIFSIYKLKTSDPAKASLADCLQAGSEQVAAGYVIYGSSVVMVYTTGHGVHG
EEEEEEHHEEEEEEEECCCCCCHHHHHHHHHCCCCHHEEEEEEECCCEEEEEEECCCCCC
FTYDPTIGEFLLSDENITTPKRGKYYSMNEGSYAQFNEGTKRYLDYIKTEDKATNRPYST
EEECCCHHHHEECCCCCCCCCCCCEEECCCCCCHHCCCCHHHHHHHHHCCCCCCCCCCCH
RYIGSLVADFHRNLLTGGIFIYPPTGKHPNGKLRLMYEANPLAFICEQAGGRATNGKERI
HHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEEECCCCEEEEECCCCCCCCCCCEE
LDIKPTELHQRTPLYIGSTDDVMVAEEFEQGKR
EECCCHHHHCCCCEEECCCCCEEEHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA