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The map label for this gene is zupT

Identifier: 78188140

GI number: 78188140

Start: 178260

End: 179066

Strand: Reverse

Name: zupT

Synonym: Cag_0157

Alternate gene names: 78188140

Gene position: 179066-178260 (Counterclockwise)

Preceding gene: 78188141

Following gene: 78188138

Centisome position: 6.96

GC content: 45.6

Gene sequence:

>807_bases
ATGACCGACAACATTCTCTTTGCCTTTGCTTTAACGCTTTTTGCGGGGTTATCAACCGGTGTTGGTAGCCTTATTGGCTT
GCTCTCAAAAGAGTTCAATCCCAAAGTGCTTACCATTTCGCTGGGCTTTTCAGCCGGTGTTATGATTTACGTTGCCATGA
TTGAAATTATGGTAAAGGCACGCGAATCGCTGGTGGTGGGCATTGGTGCCGAAATGGGCAAAGTGGTAACGGTGCTCTCC
TTTTTTGCGGGAATTTTTCTTATCGCTTTAATTGATAAACTCATTCCCTCCTACGAAAATCCCCATGAGCTGAATGTGGC
ACAAAAGCTTGAAGAGTGCAGCGAAAACCAAAAAAAGAAACTGATGCGCATGGGGCTTTTTTCGGCGGTGGCAATTGGCA
TCCACAACTTCCCCGAAGGGTTGGCAACCTTTATGAGCGGCTTAAGTAATCCAACACTTGGCGTGAGCATTGCCGTAGCT
ATTGCCATTCACAACATTCCTGAAGGCTTAGCAGTATCGGCACCAATTTTTTATGCTACTCAAAGTCGTAAAAAAGCATT
TATACTTTCATTTTTATCAGGACTTGCTGAACCTGTTGGTGCACTTATTGGCTACTTTTTGCTTCGCTCATTTTTTAGCC
CCTCGCTGTTTGGCGTCGTGTTTGGCGCCGTAGCCGGCATTATGGTTTATATTTCGCTTGATGAGTTGCTGCCCGCTGCC
GAAGAGTATGGAGAGCACCATTTCGCAATTGGTGGGGTAATTGCAGGCATGGTGGTTATGGCAATAAGTTTGCTGCTGTT
TACCTGA

Upstream 100 bases:

>100_bases
AACTCACCTTCGTCATTCCCGCGAAAGCGGGAATCCAGAATTGTGCAGATAGAATGACAAAAGGATAAAAAGTTTATGAC
GTATTCAGAATAGATTCCTT

Downstream 100 bases:

>100_bases
AAAGAGGCAATAAATGAGCGTTACTCCCCTCGCCCATTCTCAAACGGCACTCCCACTTCGCGAGGCGCTTGAGCTTTGCC
CACAAAACCAGCAAGCACCA

Product: zinc transporter ZupT

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MTDNILFAFALTLFAGLSTGVGSLIGLLSKEFNPKVLTISLGFSAGVMIYVAMIEIMVKARESLVVGIGAEMGKVVTVLS
FFAGIFLIALIDKLIPSYENPHELNVAQKLEECSENQKKKLMRMGLFSAVAIGIHNFPEGLATFMSGLSNPTLGVSIAVA
IAIHNIPEGLAVSAPIFYATQSRKKAFILSFLSGLAEPVGALIGYFLLRSFFSPSLFGVVFGAVAGIMVYISLDELLPAA
EEYGEHHFAIGGVIAGMVVMAISLLLFT

Sequences:

>Translated_268_residues
MTDNILFAFALTLFAGLSTGVGSLIGLLSKEFNPKVLTISLGFSAGVMIYVAMIEIMVKARESLVVGIGAEMGKVVTVLS
FFAGIFLIALIDKLIPSYENPHELNVAQKLEECSENQKKKLMRMGLFSAVAIGIHNFPEGLATFMSGLSNPTLGVSIAVA
IAIHNIPEGLAVSAPIFYATQSRKKAFILSFLSGLAEPVGALIGYFLLRSFFSPSLFGVVFGAVAGIMVYISLDELLPAA
EEYGEHHFAIGGVIAGMVVMAISLLLFT
>Mature_267_residues
TDNILFAFALTLFAGLSTGVGSLIGLLSKEFNPKVLTISLGFSAGVMIYVAMIEIMVKARESLVVGIGAEMGKVVTVLSF
FAGIFLIALIDKLIPSYENPHELNVAQKLEECSENQKKKLMRMGLFSAVAIGIHNFPEGLATFMSGLSNPTLGVSIAVAI
AIHNIPEGLAVSAPIFYATQSRKKAFILSFLSGLAEPVGALIGYFLLRSFFSPSLFGVVFGAVAGIMVYISLDELLPAAE
EYGEHHFAIGGVIAGMVVMAISLLLFT

Specific function: Mediates zinc uptake. May also transport other divalent cations

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily

Homologues:

Organism=Homo sapiens, GI229577418, Length=293, Percent_Identity=28.3276450511945, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI229577422, Length=300, Percent_Identity=28.6666666666667, Blast_Score=68, Evalue=7e-12,
Organism=Escherichia coli, GI1789419, Length=258, Percent_Identity=36.8217054263566, Blast_Score=155, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI17507805, Length=297, Percent_Identity=27.6094276094276, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6322673, Length=93, Percent_Identity=36.5591397849462, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24652846, Length=171, Percent_Identity=33.9181286549708, Blast_Score=81, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ZUPT_CHLCH (Q3AU90)

Other databases:

- EMBL:   CP000108
- RefSeq:   YP_378478.1
- STRING:   Q3AU90
- GeneID:   3747722
- GenomeReviews:   CP000108_GR
- KEGG:   cch:Cag_0157
- eggNOG:   COG0428
- HOGENOM:   HBG620552
- OMA:   VSVPIYY
- ProtClustDB:   PRK04201
- BioCyc:   CCHL340177:CAG_0157-MONOMER
- HAMAP:   MF_00548
- InterPro:   IPR003689

Pfam domain/function: PF02535 Zip

EC number: NA

Molecular weight: Translated: 28474; Mature: 28343

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x44857714)-; HASH(0x44997d18)-; HASH(0x449cbde0)-; HASH(0x4489a560)-; HASH(0x44a69d24)-; HASH(0x44991a3c)-; HASH(0x44a48e5c)-; HASH(0x44a4cb7c)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDNILFAFALTLFAGLSTGVGSLIGLLSKEFNPKVLTISLGFSAGVMIYVAMIEIMVKA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHH
RESLVVGIGAEMGKVVTVLSFFAGIFLIALIDKLIPSYENPHELNVAQKLEECSENQKKK
HHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
LMRMGLFSAVAIGIHNFPEGLATFMSGLSNPTLGVSIAVAIAIHNIPEGLAVSAPIFYAT
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEECCCHHEEH
QSRKKAFILSFLSGLAEPVGALIGYFLLRSFFSPSLFGVVFGAVAGIMVYISLDELLPAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEYGEHHFAIGGVIAGMVVMAISLLLFT
HHHCCCHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure 
TDNILFAFALTLFAGLSTGVGSLIGLLSKEFNPKVLTISLGFSAGVMIYVAMIEIMVKA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHH
RESLVVGIGAEMGKVVTVLSFFAGIFLIALIDKLIPSYENPHELNVAQKLEECSENQKKK
HHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
LMRMGLFSAVAIGIHNFPEGLATFMSGLSNPTLGVSIAVAIAIHNIPEGLAVSAPIFYAT
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEECCCHHEEH
QSRKKAFILSFLSGLAEPVGALIGYFLLRSFFSPSLFGVVFGAVAGIMVYISLDELLPAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEYGEHHFAIGGVIAGMVVMAISLLLFT
HHHCCCHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA