Click here to switch to the map view.

The map label for this gene is 78188089

Identifier: 78188089

GI number: 78188089

Start: 120516

End: 121655

Strand: Reverse

Name: 78188089

Synonym: Cag_0106

Alternate gene names: NA

Gene position: 121655-120516 (Counterclockwise)

Preceding gene: 78188090

Following gene: 78188088

Centisome position: 4.73

GC content: 48.42

Gene sequence:

>1140_bases
ATGAAAAAACGCTTATTCACCCCTGGTCCAACGCCTGTTCCCGAAAATGTGATGCTGCGCATGGCAGCTCCCATTATTCA
CCATCGTAACCCTGAGTTCATGGAAATTCTGGCTCGGGTTCATGCTGATTTACAATACCTTTTCTGCACCACTCGCCCCG
TTGTGGTGCTAAGCTGCTCAGGCACGGGTGGCATGGAAGCTGCTATTTCAAGCCTTTTTAATGAGGGCGATAAGGTTCTT
ACCATTAATGGAGGCAAGTTTGGTGAGCGCTGGGGTGAATTGGTGCGCACCTTCACCGGTAATAATGTTGAAGAGATGGT
TGAATGGGGGCAAGCAATTCAACCCGAACAACTGCTTGCTCTTTTAAAAGCGCACCCCGATGCCAAAGGCATCTGCCTTA
CCCACTCTGAAACCTCAACCGGTACGGCAACCGATATTAAAGCCCTTAGCGCTTTAATTCATGAACATTCCAATGCTTTA
GTGTTGGTGGATGGCATTACCGCAATTGGTGCGCATGAATTCCTTTTTGATGCGTGGGGAATTGATATTTGCATTACAGG
CTCACAAAAAGGGTTGATGATGCCTCCCGGTTTAGCACTTGTTGCAATTTCAGAGCGTGCTGAAGCGGCAATTAAGGCTC
GCAAAAGCAGCAAAAACTATTACCTCAGCTTAAAAAAAGCGCTGAAATCGCACGCTGGGGACGACACCCCCTTCACACCA
GCCGCATCGTTAGTTATTGGCTTAGATGAAGCGTTGCAAATGATTAAAGCTGAAGGAATTGAAAATATTTGGAAGCGCCA
CGAAAGCCTTGCAAGCGCCTGCCGTCAAGGGTGCCAAGCGCTTGGCATGAAGCTCTTTAGCAGTTCCCCCTCTTTTGCTG
TAACCCCCGTGTGGCTTCCCGAAGGCGTTGATTGGAAGGCTTTTAACACGGCGCTTAAGGTGAATAACGGCATTACCGTA
GCCGCTGGACAGGATGCTTATAAGGATAAAATTTTCCGCATTTCACACCTTGGCTACTACGACGAGCTTGATATGTTGAC
CGTTATCGGCGGCATTGAACGCGCCTTTAAAGAGATCAACCACCCCTTTACCATTGGGGCTGGCGTTCAAGCTGTCCAAC
AAGCCTTTCTTGGTAACTGA

Upstream 100 bases:

>100_bases
AATACCACCCCGAAGCGGCTCCCGGTCCACACGATTCGCACTACCTTTTTGATGAATTCACCTCGCTTATGGCAAGGTCT
TAACGCTCTTTGGTTTTGAG

Downstream 100 bases:

>100_bases
TCGCCACTAACGCATGTTACTATGCTAATTCTGAACTCTCTCCTGCTGGCTTTGGCTTTTTTTTCATCCATGCAGGAGGG
GTTCAACCACTACCAGCAAC

Product: class V aminotransferase

Products: NA

Alternate protein names: Tritium exchange subunit [H]

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MKKRLFTPGPTPVPENVMLRMAAPIIHHRNPEFMEILARVHADLQYLFCTTRPVVVLSCSGTGGMEAAISSLFNEGDKVL
TINGGKFGERWGELVRTFTGNNVEEMVEWGQAIQPEQLLALLKAHPDAKGICLTHSETSTGTATDIKALSALIHEHSNAL
VLVDGITAIGAHEFLFDAWGIDICITGSQKGLMMPPGLALVAISERAEAAIKARKSSKNYYLSLKKALKSHAGDDTPFTP
AASLVIGLDEALQMIKAEGIENIWKRHESLASACRQGCQALGMKLFSSSPSFAVTPVWLPEGVDWKAFNTALKVNNGITV
AAGQDAYKDKIFRISHLGYYDELDMLTVIGGIERAFKEINHPFTIGAGVQAVQQAFLGN

Sequences:

>Translated_379_residues
MKKRLFTPGPTPVPENVMLRMAAPIIHHRNPEFMEILARVHADLQYLFCTTRPVVVLSCSGTGGMEAAISSLFNEGDKVL
TINGGKFGERWGELVRTFTGNNVEEMVEWGQAIQPEQLLALLKAHPDAKGICLTHSETSTGTATDIKALSALIHEHSNAL
VLVDGITAIGAHEFLFDAWGIDICITGSQKGLMMPPGLALVAISERAEAAIKARKSSKNYYLSLKKALKSHAGDDTPFTP
AASLVIGLDEALQMIKAEGIENIWKRHESLASACRQGCQALGMKLFSSSPSFAVTPVWLPEGVDWKAFNTALKVNNGITV
AAGQDAYKDKIFRISHLGYYDELDMLTVIGGIERAFKEINHPFTIGAGVQAVQQAFLGN
>Mature_379_residues
MKKRLFTPGPTPVPENVMLRMAAPIIHHRNPEFMEILARVHADLQYLFCTTRPVVVLSCSGTGGMEAAISSLFNEGDKVL
TINGGKFGERWGELVRTFTGNNVEEMVEWGQAIQPEQLLALLKAHPDAKGICLTHSETSTGTATDIKALSALIHEHSNAL
VLVDGITAIGAHEFLFDAWGIDICITGSQKGLMMPPGLALVAISERAEAAIKARKSSKNYYLSLKKALKSHAGDDTPFTP
AASLVIGLDEALQMIKAEGIENIWKRHESLASACRQGCQALGMKLFSSSPSFAVTPVWLPEGVDWKAFNTALKVNNGITV
AAGQDAYKDKIFRISHLGYYDELDMLTVIGGIERAFKEINHPFTIGAGVQAVQQAFLGN

Specific function: Soluble hydrogenase catalyzes both production and consumption of hydrogen from suitable artificial electron donors or acceptors. This subunit catalyzes the tritium-exchange activity [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=355, Percent_Identity=30.7042253521127, Blast_Score=148, Evalue=7e-36,
Organism=Caenorhabditis elegans, GI17536281, Length=347, Percent_Identity=30.835734870317, Blast_Score=141, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6321079, Length=360, Percent_Identity=28.8888888888889, Blast_Score=120, Evalue=4e-28,
Organism=Drosophila melanogaster, GI17530823, Length=346, Percent_Identity=29.4797687861272, Blast_Score=155, Evalue=5e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 41070; Mature: 41070

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRLFTPGPTPVPENVMLRMAAPIIHHRNPEFMEILARVHADLQYLFCTTRPVVVLSCS
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEECCCCEEEEEEC
GTGGMEAAISSLFNEGDKVLTINGGKFGERWGELVRTFTGNNVEEMVEWGQAIQPEQLLA
CCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHH
LLKAHPDAKGICLTHSETSTGTATDIKALSALIHEHSNALVLVDGITAIGAHEFLFDAWG
HHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCC
IDICITGSQKGLMMPPGLALVAISERAEAAIKARKSSKNYYLSLKKALKSHAGDDTPFTP
CEEEEECCCCCCCCCCCEEEEEECHHHHHHHHHHHCCCCCEEHHHHHHHHCCCCCCCCCC
AASLVIGLDEALQMIKAEGIENIWKRHESLASACRQGCQALGMKLFSSSPSFAVTPVWLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECC
EGVDWKAFNTALKVNNGITVAAGQDAYKDKIFRISHLGYYDELDMLTVIGGIERAFKEIN
CCCCCHHHHEEEEECCCEEEEECCHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHCC
HPFTIGAGVQAVQQAFLGN
CCEEECHHHHHHHHHHCCC
>Mature Secondary Structure
MKKRLFTPGPTPVPENVMLRMAAPIIHHRNPEFMEILARVHADLQYLFCTTRPVVVLSCS
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEECCCCEEEEEEC
GTGGMEAAISSLFNEGDKVLTINGGKFGERWGELVRTFTGNNVEEMVEWGQAIQPEQLLA
CCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHH
LLKAHPDAKGICLTHSETSTGTATDIKALSALIHEHSNALVLVDGITAIGAHEFLFDAWG
HHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCC
IDICITGSQKGLMMPPGLALVAISERAEAAIKARKSSKNYYLSLKKALKSHAGDDTPFTP
CEEEEECCCCCCCCCCCEEEEEECHHHHHHHHHHHCCCCCEEHHHHHHHHCCCCCCCCCC
AASLVIGLDEALQMIKAEGIENIWKRHESLASACRQGCQALGMKLFSSSPSFAVTPVWLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECC
EGVDWKAFNTALKVNNGITVAAGQDAYKDKIFRISHLGYYDELDMLTVIGGIERAFKEIN
CCCCCHHHHEEEEECCCEEEEECCHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHCC
HPFTIGAGVQAVQQAFLGN
CCEEECHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2513553 [H]