Click here to switch to the map view.

The map label for this gene is cph2 [H]

Identifier: 78067984

GI number: 78067984

Start: 3685530

End: 3686888

Strand: Direct

Name: cph2 [H]

Synonym: Bcep18194_A6515

Alternate gene names: 78067984

Gene position: 3685530-3686888 (Clockwise)

Preceding gene: 78067983

Following gene: 78067988

Centisome position: 99.77

GC content: 69.09

Gene sequence:

>1359_bases
ATGGAAGGCATCCTGATCCAGCACACGACACGCCGTCAGCTCTGGTTCGGCGCACTGACGGCGCTCGTCATCGTGCTCGC
GCTCGGGATCGCCGCGCCGCACGCGAACGTTGCGCTGCCGGCCGTCGAGCCGTTCATGCCGATGTGTGCGCTCACCGTGT
TCACCACCGCGAGCATCGCGGCGTTCTTTCTTGGCGCGCAGTTCACCGTGACGCGCCAGCCGGTGCTCGGCGCGCTCGGC
GGCGCCTACGCGTTCACCGCACTCGCCGTCGCATTGCAACTGCTCACCTTTCCCGGCGTGTTCGCGCCACACGGGCTGTT
CGGCGCGCAACCGCAAAGCGCCGCGTGGATGTGGATCTTCTGGCATGCCGGCTTCCCGAGTTTCGTGATGGTCGCGCTGC
TCGCGCGCGAGCGGCTGGCGCGCGCACCGATCGGCGCGCGGCAGACACGCTGGTGGACGCTCGCGCTGATCGGCGGGCCG
GCTGTCGTCGCCGGGCTGCTTTGCCTGTTCGTGCTGAACGTGTCGCTGCCGCCCGCGTTTCATCCGCCGGGCGACGCGGC
CGTGCTGCCCGTCAACGCCGTCGCGCTGGTCGTGTGGCTGCTCAACGCGCTGGCGCTCGTGGCGGTACTGGCCACCGGCC
GGCTGCGCACGACGCTCGACCTGTGGCTCGCGATCGCGGTGCTCGCGTGCCTGACCGACACGACGCTGAACCTGATGAGC
ACCGATCGCTTCACGGTCGGCTGGTATCTCGCACGCGTGTTCAGCATGTTCACGCCAGGCGTGCTCGTGTGCGTGCTCGC
GTGGGAAGTGACGATGCTGTACCAGCGGCTGCTCGAGGCGCACGCGACGCTGATCCGTTCGTCCGCACGCGACGGCCTGA
CGGGCGCGTTCAACCGCATGCACTTCAACGATCATTTCCACACGCTGTTCCTGCAGGCGCGACGGCAAGGCGAACCGCTG
TCGTTGCTGATGGTCGATGTCGACCGCTTCAAGGCATACAACGATGCGTTCGGTCACGTGAAGGGCGACGCATGCCTGAT
CGCGGTCGCGAATGCGCTGGCCGGCGCGGTGCGGCGGCCGGCGGACATCGTCGCGCGCTACGGCGGCGAGGAGTTCGCGA
TCGTGCTGCCGAACACGGGCGCGCGCGGCGCGCGGGTCGTCGCCGAGGAAGCGCGCGAAGCGGTGCTGCGGCTCGATCTC
GCGATGCCGACGGCACCCGCCGGACGCGTGAGCGTGAGCGTCGGCTGCGCGACCGTGTCGCCCGACGATCTGTCGACACC
CGATGCGTTGATCGAAGCCGCCGATGCCGCGCTGTATCGTGCGAAGGATACGGGGCGAAACAGGGTCGTCACCGCCTGA

Upstream 100 bases:

>100_bases
CATAACGCGATAGGATCAGGCCGCACCGGTCGCGCAGCGGCCGGTTGCCTGTCGCCCGGCGCAAGACCGGGCGTTTCCGC
CTACGTGCCCGGGGAACACC

Downstream 100 bases:

>100_bases
AAACGTCTGCTGTTTGGCTATTTGTTACGGTCATTGTGACCGGAATAATCCGCCGTTACGGATTGCGGAACAGGGAAACG
ATCGCTTACAGCCGGTGTTG

Product: diguanylate cyclase

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MEGILIQHTTRRQLWFGALTALVIVLALGIAAPHANVALPAVEPFMPMCALTVFTTASIAAFFLGAQFTVTRQPVLGALG
GAYAFTALAVALQLLTFPGVFAPHGLFGAQPQSAAWMWIFWHAGFPSFVMVALLARERLARAPIGARQTRWWTLALIGGP
AVVAGLLCLFVLNVSLPPAFHPPGDAAVLPVNAVALVVWLLNALALVAVLATGRLRTTLDLWLAIAVLACLTDTTLNLMS
TDRFTVGWYLARVFSMFTPGVLVCVLAWEVTMLYQRLLEAHATLIRSSARDGLTGAFNRMHFNDHFHTLFLQARRQGEPL
SLLMVDVDRFKAYNDAFGHVKGDACLIAVANALAGAVRRPADIVARYGGEEFAIVLPNTGARGARVVAEEAREAVLRLDL
AMPTAPAGRVSVSVGCATVSPDDLSTPDALIEAADAALYRAKDTGRNRVVTA

Sequences:

>Translated_452_residues
MEGILIQHTTRRQLWFGALTALVIVLALGIAAPHANVALPAVEPFMPMCALTVFTTASIAAFFLGAQFTVTRQPVLGALG
GAYAFTALAVALQLLTFPGVFAPHGLFGAQPQSAAWMWIFWHAGFPSFVMVALLARERLARAPIGARQTRWWTLALIGGP
AVVAGLLCLFVLNVSLPPAFHPPGDAAVLPVNAVALVVWLLNALALVAVLATGRLRTTLDLWLAIAVLACLTDTTLNLMS
TDRFTVGWYLARVFSMFTPGVLVCVLAWEVTMLYQRLLEAHATLIRSSARDGLTGAFNRMHFNDHFHTLFLQARRQGEPL
SLLMVDVDRFKAYNDAFGHVKGDACLIAVANALAGAVRRPADIVARYGGEEFAIVLPNTGARGARVVAEEAREAVLRLDL
AMPTAPAGRVSVSVGCATVSPDDLSTPDALIEAADAALYRAKDTGRNRVVTA
>Mature_452_residues
MEGILIQHTTRRQLWFGALTALVIVLALGIAAPHANVALPAVEPFMPMCALTVFTTASIAAFFLGAQFTVTRQPVLGALG
GAYAFTALAVALQLLTFPGVFAPHGLFGAQPQSAAWMWIFWHAGFPSFVMVALLARERLARAPIGARQTRWWTLALIGGP
AVVAGLLCLFVLNVSLPPAFHPPGDAAVLPVNAVALVVWLLNALALVAVLATGRLRTTLDLWLAIAVLACLTDTTLNLMS
TDRFTVGWYLARVFSMFTPGVLVCVLAWEVTMLYQRLLEAHATLIRSSARDGLTGAFNRMHFNDHFHTLFLQARRQGEPL
SLLMVDVDRFKAYNDAFGHVKGDACLIAVANALAGAVRRPADIVARYGGEEFAIVLPNTGARGARVVAEEAREAVLRLDL
AMPTAPAGRVSVSVGCATVSPDDLSTPDALIEAADAALYRAKDTGRNRVVTA

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI1787262, Length=235, Percent_Identity=33.1914893617021, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1786584, Length=232, Percent_Identity=31.4655172413793, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI87081881, Length=199, Percent_Identity=34.6733668341709, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI145693134, Length=161, Percent_Identity=40.3726708074534, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI87082007, Length=206, Percent_Identity=30.5825242718447, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788085, Length=457, Percent_Identity=24.507658643326, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1788381, Length=163, Percent_Identity=33.7423312883436, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI87081977, Length=176, Percent_Identity=32.3863636363636, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787816, Length=175, Percent_Identity=36.5714285714286, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1787802, Length=164, Percent_Identity=31.7073170731707, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788956, Length=233, Percent_Identity=27.4678111587983, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787056, Length=167, Percent_Identity=28.7425149700599, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87081974, Length=168, Percent_Identity=25, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1787541, Length=159, Percent_Identity=30.8176100628931, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 48354; Mature: 48354

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGILIQHTTRRQLWFGALTALVIVLALGIAAPHANVALPAVEPFMPMCALTVFTTASIA
CCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHHH
AFFLGAQFTVTRQPVLGALGGAYAFTALAVALQLLTFPGVFAPHGLFGAQPQSAAWMWIF
HHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEE
WHAGFPSFVMVALLARERLARAPIGARQTRWWTLALIGGPAVVAGLLCLFVLNVSLPPAF
EECCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCCCC
HPPGDAAVLPVNAVALVVWLLNALALVAVLATGRLRTTLDLWLAIAVLACLTDTTLNLMS
CCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
TDRFTVGWYLARVFSMFTPGVLVCVLAWEVTMLYQRLLEAHATLIRSSARDGLTGAFNRM
CCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHC
HFNDHFHTLFLQARRQGEPLSLLMVDVDRFKAYNDAFGHVKGDACLIAVANALAGAVRRP
CCCCHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC
ADIVARYGGEEFAIVLPNTGARGARVVAEEAREAVLRLDLAMPTAPAGRVSVSVGCATVS
HHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECC
PDDLSTPDALIEAADAALYRAKDTGRNRVVTA
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MEGILIQHTTRRQLWFGALTALVIVLALGIAAPHANVALPAVEPFMPMCALTVFTTASIA
CCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHHH
AFFLGAQFTVTRQPVLGALGGAYAFTALAVALQLLTFPGVFAPHGLFGAQPQSAAWMWIF
HHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEE
WHAGFPSFVMVALLARERLARAPIGARQTRWWTLALIGGPAVVAGLLCLFVLNVSLPPAF
EECCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCCCC
HPPGDAAVLPVNAVALVVWLLNALALVAVLATGRLRTTLDLWLAIAVLACLTDTTLNLMS
CCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
TDRFTVGWYLARVFSMFTPGVLVCVLAWEVTMLYQRLLEAHATLIRSSARDGLTGAFNRM
CCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHC
HFNDHFHTLFLQARRQGEPLSLLMVDVDRFKAYNDAFGHVKGDACLIAVANALAGAVRRP
CCCCHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC
ADIVARYGGEEFAIVLPNTGARGARVVAEEAREAVLRLDLAMPTAPAGRVSVSVGCATVS
HHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECC
PDDLSTPDALIEAADAALYRAKDTGRNRVVTA
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]