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The map label for this gene is mrdB [H]

Identifier: 78067934

GI number: 78067934

Start: 3632645

End: 3633793

Strand: Direct

Name: mrdB [H]

Synonym: Bcep18194_A6465

Alternate gene names: 78067934

Gene position: 3632645-3633793 (Clockwise)

Preceding gene: 78067933

Following gene: 78067948

Centisome position: 98.34

GC content: 65.19

Gene sequence:

>1149_bases
ATGCAATTCGACAAGCGCGCCTGGCTCGACAAGATCAAGCAGATGTTCGCGGGCTTCGACCGCCCGCTCGCCCTCATCGT
GTTCCTGCTGCTGTGCGTCGGCATCGTCACGCTGTACAGCGCGGCGATCGACATGCCGGGTCGCGTCGAGGACCAGTTGC
GCAACATCCTGCTGACGTTCGTGCTGATGTGGGTGATCGCCAACATCCCGCCCACGACGCTGATGCGCTTCGCGGTCCCG
CTCTACACGTTCGGAGTCGCGCTATTGGTCGCGGTCGCGTTGTTCGGGATGACCAAGAAGGGCGCGAAGCGCTGGCTGAA
CGTCGGCGTCGTGATCCAGCCGTCGGAAATCCTCAAGATCGCGACACCGCTGATGCTCGCGTGGTACTACCAGCGCCGCG
AAGGCGGGCTGCGCTGGTACGACTTCATCGCCGCGTTCGGGATCCTGCTGGTACCGGTCGGGCTGATCGCGAAGCAGCCC
GACCTCGGCACGGGCCTGCTCGTGTTCGCGGCCGGCTTCTTCGTGATCTATCTCGCCGGCCTGTCGTTCAAGCTGATCGT
GCCGGTGCTCGTCGCGGGCGTGATCGCGGTCGGCTCGATCGCCGTGTTCGAAGAGCGCATCTGCCAGCCCGAAGTGCAGT
GGCCGCTGATGCACGATTACCAGAAGCACCGCGTGTGTACGCTGCTCGATCCGACTTCCGACCCGCTCGGCAAGGGCTTC
CACACGATCCAGGCCGTGATCGCGATCGGCTCGGGCGGCGTGCTCGGCAAGGGCTACCTGAAAGGCACGCAGGCGCACCT
CGAATTCATTCCGGAGAAGCACACCGACTTCATCTTCGCGGTGTTCTCCGAGGAATGGGGGCTCGCCGGCGGGCTCGTGC
TGCTGACGCTGTACATGGCGCTGATCGCGCGCGGGCTCTATATCGCCGCGCAGGGCGCGACACTGTTCGGCCGCCTGCTT
GCGGGCTCGCTCACGCTCGCGTTCTTCGTCTACGCGTTCGTCAACATCGGGATGGTGAGCGGCGTGCTGCCGGTCGTCGG
CGTGCCGCTGCCGTTCATGAGTTATGGCGGCACCGCGCTCACGACGCTCGGCATCGCGATCGGGATGATCATGAGCGTCG
GGCGGCAGCGGCGGTTGATGAAGAGCTGA

Upstream 100 bases:

>100_bases
ACGCGCAGCCGCTCGTCGCCACGCCGCGCGACGACAATCACCGTGCCACGGCCCCCGCGAAGGCGGCGGACGCCGGCACC
GCTCATTAACGGAGAAAGGC

Downstream 100 bases:

>100_bases
CCGCGCGGCACGCACCGCACAAAGAAAAACGGCGCCTCGGCGCCGTTTTTTTCGACCGCGCAACGCGATCGCGGCCGCAC
TTCGCCGCACCGCCCCCCGC

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MQFDKRAWLDKIKQMFAGFDRPLALIVFLLLCVGIVTLYSAAIDMPGRVEDQLRNILLTFVLMWVIANIPPTTLMRFAVP
LYTFGVALLVAVALFGMTKKGAKRWLNVGVVIQPSEILKIATPLMLAWYYQRREGGLRWYDFIAAFGILLVPVGLIAKQP
DLGTGLLVFAAGFFVIYLAGLSFKLIVPVLVAGVIAVGSIAVFEERICQPEVQWPLMHDYQKHRVCTLLDPTSDPLGKGF
HTIQAVIAIGSGGVLGKGYLKGTQAHLEFIPEKHTDFIFAVFSEEWGLAGGLVLLTLYMALIARGLYIAAQGATLFGRLL
AGSLTLAFFVYAFVNIGMVSGVLPVVGVPLPFMSYGGTALTTLGIAIGMIMSVGRQRRLMKS

Sequences:

>Translated_382_residues
MQFDKRAWLDKIKQMFAGFDRPLALIVFLLLCVGIVTLYSAAIDMPGRVEDQLRNILLTFVLMWVIANIPPTTLMRFAVP
LYTFGVALLVAVALFGMTKKGAKRWLNVGVVIQPSEILKIATPLMLAWYYQRREGGLRWYDFIAAFGILLVPVGLIAKQP
DLGTGLLVFAAGFFVIYLAGLSFKLIVPVLVAGVIAVGSIAVFEERICQPEVQWPLMHDYQKHRVCTLLDPTSDPLGKGF
HTIQAVIAIGSGGVLGKGYLKGTQAHLEFIPEKHTDFIFAVFSEEWGLAGGLVLLTLYMALIARGLYIAAQGATLFGRLL
AGSLTLAFFVYAFVNIGMVSGVLPVVGVPLPFMSYGGTALTTLGIAIGMIMSVGRQRRLMKS
>Mature_382_residues
MQFDKRAWLDKIKQMFAGFDRPLALIVFLLLCVGIVTLYSAAIDMPGRVEDQLRNILLTFVLMWVIANIPPTTLMRFAVP
LYTFGVALLVAVALFGMTKKGAKRWLNVGVVIQPSEILKIATPLMLAWYYQRREGGLRWYDFIAAFGILLVPVGLIAKQP
DLGTGLLVFAAGFFVIYLAGLSFKLIVPVLVAGVIAVGSIAVFEERICQPEVQWPLMHDYQKHRVCTLLDPTSDPLGKGF
HTIQAVIAIGSGGVLGKGYLKGTQAHLEFIPEKHTDFIFAVFSEEWGLAGGLVLLTLYMALIARGLYIAAQGATLFGRLL
AGSLTLAFFVYAFVNIGMVSGVLPVVGVPLPFMSYGGTALTTLGIAIGMIMSVGRQRRLMKS

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=382, Percent_Identity=48.1675392670157, Blast_Score=289, Evalue=2e-79,
Organism=Escherichia coli, GI1786277, Length=378, Percent_Identity=29.8941798941799, Blast_Score=156, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 41692; Mature: 41692

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFDKRAWLDKIKQMFAGFDRPLALIVFLLLCVGIVTLYSAAIDMPGRVEDQLRNILLTF
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
VLMWVIANIPPTTLMRFAVPLYTFGVALLVAVALFGMTKKGAKRWLNVGVVIQPSEILKI
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEECCHHHHHH
ATPLMLAWYYQRREGGLRWYDFIAAFGILLVPVGLIAKQPDLGTGLLVFAAGFFVIYLAG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
LSFKLIVPVLVAGVIAVGSIAVFEERICQPEVQWPLMHDYQKHRVCTLLDPTSDPLGKGF
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCEEEEECCCCCCCCCHH
HTIQAVIAIGSGGVLGKGYLKGTQAHLEFIPEKHTDFIFAVFSEEWGLAGGLVLLTLYMA
HHHHHHHHCCCCCCCCCCHHCCHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHH
LIARGLYIAAQGATLFGRLLAGSLTLAFFVYAFVNIGMVSGVLPVVGVPLPFMSYGGTAL
HHHCCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHH
TTLGIAIGMIMSVGRQRRLMKS
HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQFDKRAWLDKIKQMFAGFDRPLALIVFLLLCVGIVTLYSAAIDMPGRVEDQLRNILLTF
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
VLMWVIANIPPTTLMRFAVPLYTFGVALLVAVALFGMTKKGAKRWLNVGVVIQPSEILKI
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEECCHHHHHH
ATPLMLAWYYQRREGGLRWYDFIAAFGILLVPVGLIAKQPDLGTGLLVFAAGFFVIYLAG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
LSFKLIVPVLVAGVIAVGSIAVFEERICQPEVQWPLMHDYQKHRVCTLLDPTSDPLGKGF
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCEEEEECCCCCCCCCHH
HTIQAVIAIGSGGVLGKGYLKGTQAHLEFIPEKHTDFIFAVFSEEWGLAGGLVLLTLYMA
HHHHHHHHCCCCCCCCCCHHCCHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHH
LIARGLYIAAQGATLFGRLLAGSLTLAFFVYAFVNIGMVSGVLPVVGVPLPFMSYGGTAL
HHHCCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHH
TTLGIAIGMIMSVGRQRRLMKS
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]