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The map label for this gene is yjiA [H]

Identifier: 78067908

GI number: 78067908

Start: 3605371

End: 3606450

Strand: Direct

Name: yjiA [H]

Synonym: Bcep18194_A6439

Alternate gene names: 78067908

Gene position: 3605371-3606450 (Clockwise)

Preceding gene: 78067907

Following gene: 78067909

Centisome position: 97.6

GC content: 61.85

Gene sequence:

>1080_bases
ATGGCCACTCCCGTCACCATCCTCACCGGCTTCCTCGGCAGCGGCAAGACGACGCTGCTCAAGCGCATCCTGAACGAACA
GCACGGCATGAAGATCGCCGTGATCGAGAACGAGTTCGGCGAAGAGAACATCGACAACGAAATCCTCATCCAGGATTCGA
ACGAGCAGATCATCCAGATGAGCAACGGCTGCATCTGCTGCACGATCCGCGGCGACCTCGCGCGCACGCTCGGCGATCTG
GCCGCGAAGAAGCGCGAAGGCAAGCTCGACTTCGACCGCATCGTGATCGAGACCACCGGCCTCGCGAACCCGGGCCCGGT
CGCGCAAACCTTCTTCATCGACAGCGAAATCGCCGACGATTTCCTGCTCGACGCGGTCATCACGCTGGTCGACGCGAAGC
ACGCGAACGCGCAGCTCGACGAGCACGAAGTCGTGCAGCGCCAGGTCGGCTTCGCCGATCGCCTGTTCATCACGAAGTCG
GACCTGGTCGACGACCAGACGGTGGCCGGCCTGAAGCACCGCCTGATGCACATGAACCCGAAGGCCGTGATCAAGGTCGT
GAACTTCGGCGAAGCGGACATCAAGGAAATCTTCGACCTGCGCGGCTTCAACCTGAACGCGAAGCTCGAGATCGACCCCG
ACTTCCTCGCCGAAGACGATCACGCGCATCACCACCACGATCACGACCATGATCACGATCACGCCAATTGCGACCACGAT
CACGGTCAATGCGCGCACGATCACGACCACGGCCACCACCATCACCACCACGCGCACCACGACGACAAGATCAAGTCGTT
CGTGTACCGCAACGACCGCCCGTTCGACCCGAACAAGCTGGAAGACTTCCTCGGCGGCATCCTGCAGATCTACGGCGAGC
GGATGCTGCGCTACAAGGGCGTGCTGTACATGAAGGGCGTCGACCGCAAGGTCGTGTTCCAGGGCGTGCACCAGATGATG
GGCAGCGACCTCGCCTCGAAGTGGCTGCCGGTCGAGAAGAAGACGAACAAGATGGTGTTCATCGGCGTCGATCTGCCGCA
GGACCTGATCACCGACGGCCTCGACGCCTGCCTCGCCTGA

Upstream 100 bases:

>100_bases
GGTATGTTTCAATGGATGGTTGTGCGCCCCGGCTGGCAAAGCCCCGGGCGCGACGCACATCCTGGTTTTGACCCCGATTC
ACGAACCACAGGCGATTGAC

Downstream 100 bases:

>100_bases
CGCGCGCGGGCAACCGTCGCGCCCCCGCCGCACGGCCGCCTCGCGGGCGGTTGCTGCGGCCGCGGGGCGCCTTTTCCGGG
CAGGGTTTCGCCGTCATCGC

Product: cobalamin synthesis protein/P47K

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:

>359_residues
MATPVTILTGFLGSGKTTLLKRILNEQHGMKIAVIENEFGEENIDNEILIQDSNEQIIQMSNGCICCTIRGDLARTLGDL
AAKKREGKLDFDRIVIETTGLANPGPVAQTFFIDSEIADDFLLDAVITLVDAKHANAQLDEHEVVQRQVGFADRLFITKS
DLVDDQTVAGLKHRLMHMNPKAVIKVVNFGEADIKEIFDLRGFNLNAKLEIDPDFLAEDDHAHHHHDHDHDHDHANCDHD
HGQCAHDHDHGHHHHHHAHHDDKIKSFVYRNDRPFDPNKLEDFLGGILQIYGERMLRYKGVLYMKGVDRKVVFQGVHQMM
GSDLASKWLPVEKKTNKMVFIGVDLPQDLITDGLDACLA

Sequences:

>Translated_359_residues
MATPVTILTGFLGSGKTTLLKRILNEQHGMKIAVIENEFGEENIDNEILIQDSNEQIIQMSNGCICCTIRGDLARTLGDL
AAKKREGKLDFDRIVIETTGLANPGPVAQTFFIDSEIADDFLLDAVITLVDAKHANAQLDEHEVVQRQVGFADRLFITKS
DLVDDQTVAGLKHRLMHMNPKAVIKVVNFGEADIKEIFDLRGFNLNAKLEIDPDFLAEDDHAHHHHDHDHDHDHANCDHD
HGQCAHDHDHGHHHHHHAHHDDKIKSFVYRNDRPFDPNKLEDFLGGILQIYGERMLRYKGVLYMKGVDRKVVFQGVHQMM
GSDLASKWLPVEKKTNKMVFIGVDLPQDLITDGLDACLA
>Mature_358_residues
ATPVTILTGFLGSGKTTLLKRILNEQHGMKIAVIENEFGEENIDNEILIQDSNEQIIQMSNGCICCTIRGDLARTLGDLA
AKKREGKLDFDRIVIETTGLANPGPVAQTFFIDSEIADDFLLDAVITLVDAKHANAQLDEHEVVQRQVGFADRLFITKSD
LVDDQTVAGLKHRLMHMNPKAVIKVVNFGEADIKEIFDLRGFNLNAKLEIDPDFLAEDDHAHHHHDHDHDHDHANCDHDH
GQCAHDHDHGHHHHHHAHHDDKIKSFVYRNDRPFDPNKLEDFLGGILQIYGERMLRYKGVLYMKGVDRKVVFQGVHQMMG
SDLASKWLPVEKKTNKMVFIGVDLPQDLITDGLDACLA

Specific function: Binds GTP. May function as GTP-dependent regulator [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=359, Percent_Identity=30.3621169916435, Blast_Score=161, Evalue=8e-40,
Organism=Homo sapiens, GI126722884, Length=359, Percent_Identity=30.3621169916435, Blast_Score=161, Evalue=9e-40,
Organism=Homo sapiens, GI146231952, Length=359, Percent_Identity=30.9192200557103, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI148727351, Length=359, Percent_Identity=30.3621169916435, Blast_Score=158, Evalue=8e-39,
Organism=Homo sapiens, GI223941779, Length=359, Percent_Identity=30.08356545961, Blast_Score=152, Evalue=3e-37,
Organism=Homo sapiens, GI223941776, Length=350, Percent_Identity=29.1428571428571, Blast_Score=144, Evalue=9e-35,
Organism=Homo sapiens, GI119120938, Length=144, Percent_Identity=43.75, Blast_Score=124, Evalue=2e-28,
Organism=Escherichia coli, GI87082430, Length=347, Percent_Identity=38.328530259366, Blast_Score=224, Evalue=5e-60,
Organism=Escherichia coli, GI1788499, Length=177, Percent_Identity=32.2033898305085, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324356, Length=224, Percent_Identity=29.4642857142857, Blast_Score=114, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 40473; Mature: 40342

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATPVTILTGFLGSGKTTLLKRILNEQHGMKIAVIENEFGEENIDNEILIQDSNEQIIQM
CCCCHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEECCCCEEEEE
SNGCICCTIRGDLARTLGDLAAKKREGKLDFDRIVIETTGLANPGPVAQTFFIDSEIADD
CCCEEEEEECHHHHHHHHHHHHHHCCCCCCHHEEEEEECCCCCCCCCEEEEEECHHHHHH
FLLDAVITLVDAKHANAQLDEHEVVQRQVGFADRLFITKSDLVDDQTVAGLKHRLMHMNP
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHEEEEEHHHCCCHHHHHHHHHHHHCCCH
KAVIKVVNFGEADIKEIFDLRGFNLNAKLEIDPDFLAEDDHAHHHHDHDHDHDHANCDHD
HHEEEEECCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC
HGQCAHDHDHGHHHHHHAHHDDKIKSFVYRNDRPFDPNKLEDFLGGILQIYGERMLRYKG
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
VLYMKGVDRKVVFQGVHQMMGSDLASKWLPVEKKTNKMVFIGVDLPQDLITDGLDACLA
EEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
ATPVTILTGFLGSGKTTLLKRILNEQHGMKIAVIENEFGEENIDNEILIQDSNEQIIQM
CCCHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEECCCCEEEEE
SNGCICCTIRGDLARTLGDLAAKKREGKLDFDRIVIETTGLANPGPVAQTFFIDSEIADD
CCCEEEEEECHHHHHHHHHHHHHHCCCCCCHHEEEEEECCCCCCCCCEEEEEECHHHHHH
FLLDAVITLVDAKHANAQLDEHEVVQRQVGFADRLFITKSDLVDDQTVAGLKHRLMHMNP
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHEEEEEHHHCCCHHHHHHHHHHHHCCCH
KAVIKVVNFGEADIKEIFDLRGFNLNAKLEIDPDFLAEDDHAHHHHDHDHDHDHANCDHD
HHEEEEECCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC
HGQCAHDHDHGHHHHHHAHHDDKIKSFVYRNDRPFDPNKLEDFLGGILQIYGERMLRYKG
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
VLYMKGVDRKVVFQGVHQMMGSDLASKWLPVEKKTNKMVFIGVDLPQDLITDGLDACLA
EEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 1650347 [H]