Click here to switch to the map view.

The map label for this gene is rutG [H]

Identifier: 78067828

GI number: 78067828

Start: 3524270

End: 3525577

Strand: Reverse

Name: rutG [H]

Synonym: Bcep18194_A6359

Alternate gene names: 78067828

Gene position: 3525577-3524270 (Counterclockwise)

Preceding gene: 78067829

Following gene: 78067826

Centisome position: 95.44

GC content: 68.35

Gene sequence:

>1308_bases
ATGTCCGATTCCTACTTCCCGCGCTGGCGGGTGCAATCGACCGGCGCGGCCTCGCGCGTGGTCGGCCCCGACGAGCGCCT
CGCGTGGCCGCAGATGGTCGCGATGGGCGTGCAGCACGTCGTCGCGATGTTCGGCTCGACCGTGCTCGCGCCGCTGCTGA
TGGGCTTCGACCCGAACCTGTGCATCTTCATGTCGGGCATCGGCACGCTGCTGTTCTTCGTGCTGGTCGGCGGCCGCGTG
CCGAGCTATCTCGGCTCGAGCTTCGCGTTCATCGGCCTCGTGATCGCGGTGACCGGCTACGGCGGCAGCGGCCCGAACCC
GAACATCCCGGTCGCGCTCGGCGGGATCATCGCGTGCGGCGTCGTGTACGTCGCGATCGGCGCGCTGGTGCAGGCGATCG
GCACGAACTGGATCGAGACGCTGATGCCGCCCGTCGTGACCGGCGCGGTGGTCGCGGTGATCGGGCTGAACCTGGCGCCG
ATCGCGGTCAAGGGCGTGTCCGGGTCGACCTTCGAATCGGTGATGGCGCTCGTCACGGTGCTGTGCGTCGGCGGCGTCGC
GGTGTTCTCGCGCGGCATGGTGCAGCGCCTGCTGATCCTCGTCGGGCTGGTGATCGCCTACGCGATCTACGCGGTCGTGA
CCAACGGGATGGCGCTCGGCAAGCCGATCGATTTCTCGATCGTCGAGCATGCGGCCTGGTTTGGGGTGCCGAGCTTCCGC
GCGCCGGTGTTCGATCCGCACGCGATGCTGATGCTGGCGCCGATCGCGGTGATCCTCGTCGCGGAAAACCTTGGCCACAT
CAAGGCCGTCAGCGCGATGACGGGCACCAGCCTCGATCGCTACGTGGGCCGCGCGTTCATCGGCGACGGGCTTGCGACGA
TCGTGTCGGGCAGCGTCGGCGGCACGGGCGTGACGACCTACGCGGAGAACATCGGCGTGATGGCCGTCACGCGGATCTAC
TCGACGCTCGTGTTCGCGGTCGCCGCGGTGATCGCGATCGTGCTCGGCTTCTCGCCGAAGTTCGGCGCGGTGATCCAGAC
GATTCCGGGCCCCGTGCTCGGCGGCGTGTCGATCGTCGTGTTCGGGCTGATCGCGGTGACGGGCGCGCGGATCTGGGTCG
TCAACAAGGTCGACTTCTCCGACAACCGCAACCTGATCGTCGCAGCCGTCACGCTCGTGCTCGGCGCCGGCGACTTCTCG
CTGAAGATCGGCGGCTTCGGGCTCGGCGGGATCGGCACCGCGACGTTCGGCGCGATCATCCTGTACGCGATCCTGCGTAA
GGAAAAGGAACCGGGCCCGGTGGTCTGA

Upstream 100 bases:

>100_bases
CCCGCTTGCCAGCCCCATTTCCGCTCCGTAAACTCGCGCCAGATTCCAGACCGGCGCATCCTCCGCAGCCGGCGACCGAC
TGACAGGAGCCCTTTTCCCC

Downstream 100 bases:

>100_bases
GCTTCCGGCGGGCGGTGTCGTGCCGCCCGTGTCATCTTCGGCGTCGAACGTCGCGGCGCTACGCGCCGACGTTCGACTGC
GTCTGCAGCCACGCGCAGAA

Product: xanthine/uracil tranporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 434

Protein sequence:

>435_residues
MSDSYFPRWRVQSTGAASRVVGPDERLAWPQMVAMGVQHVVAMFGSTVLAPLLMGFDPNLCIFMSGIGTLLFFVLVGGRV
PSYLGSSFAFIGLVIAVTGYGGSGPNPNIPVALGGIIACGVVYVAIGALVQAIGTNWIETLMPPVVTGAVVAVIGLNLAP
IAVKGVSGSTFESVMALVTVLCVGGVAVFSRGMVQRLLILVGLVIAYAIYAVVTNGMALGKPIDFSIVEHAAWFGVPSFR
APVFDPHAMLMLAPIAVILVAENLGHIKAVSAMTGTSLDRYVGRAFIGDGLATIVSGSVGGTGVTTYAENIGVMAVTRIY
STLVFAVAAVIAIVLGFSPKFGAVIQTIPGPVLGGVSIVVFGLIAVTGARIWVVNKVDFSDNRNLIVAAVTLVLGAGDFS
LKIGGFGLGGIGTATFGAIILYAILRKEKEPGPVV

Sequences:

>Translated_435_residues
MSDSYFPRWRVQSTGAASRVVGPDERLAWPQMVAMGVQHVVAMFGSTVLAPLLMGFDPNLCIFMSGIGTLLFFVLVGGRV
PSYLGSSFAFIGLVIAVTGYGGSGPNPNIPVALGGIIACGVVYVAIGALVQAIGTNWIETLMPPVVTGAVVAVIGLNLAP
IAVKGVSGSTFESVMALVTVLCVGGVAVFSRGMVQRLLILVGLVIAYAIYAVVTNGMALGKPIDFSIVEHAAWFGVPSFR
APVFDPHAMLMLAPIAVILVAENLGHIKAVSAMTGTSLDRYVGRAFIGDGLATIVSGSVGGTGVTTYAENIGVMAVTRIY
STLVFAVAAVIAIVLGFSPKFGAVIQTIPGPVLGGVSIVVFGLIAVTGARIWVVNKVDFSDNRNLIVAAVTLVLGAGDFS
LKIGGFGLGGIGTATFGAIILYAILRKEKEPGPVV
>Mature_434_residues
SDSYFPRWRVQSTGAASRVVGPDERLAWPQMVAMGVQHVVAMFGSTVLAPLLMGFDPNLCIFMSGIGTLLFFVLVGGRVP
SYLGSSFAFIGLVIAVTGYGGSGPNPNIPVALGGIIACGVVYVAIGALVQAIGTNWIETLMPPVVTGAVVAVIGLNLAPI
AVKGVSGSTFESVMALVTVLCVGGVAVFSRGMVQRLLILVGLVIAYAIYAVVTNGMALGKPIDFSIVEHAAWFGVPSFRA
PVFDPHAMLMLAPIAVILVAENLGHIKAVSAMTGTSLDRYVGRAFIGDGLATIVSGSVGGTGVTTYAENIGVMAVTRIYS
TLVFAVAAVIAIVLGFSPKFGAVIQTIPGPVLGGVSIVVFGLIAVTGARIWVVNKVDFSDNRNLIVAAVTLVLGAGDFSL
KIGGFGLGGIGTATFGAIILYAILRKEKEPGPVV

Specific function: May function as a proton-driven pyrimidine uptake system [H]

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081818, Length=423, Percent_Identity=70.2127659574468, Blast_Score=591, Evalue=1e-170,
Organism=Escherichia coli, GI1788843, Length=427, Percent_Identity=37.2365339578454, Blast_Score=254, Evalue=7e-69,
Organism=Escherichia coli, GI87082181, Length=476, Percent_Identity=25.6302521008403, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1790087, Length=466, Percent_Identity=24.2489270386266, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87082178, Length=410, Percent_Identity=26.3414634146341, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17558856, Length=201, Percent_Identity=29.3532338308458, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17541904, Length=219, Percent_Identity=27.3972602739726, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71993493, Length=170, Percent_Identity=32.3529411764706, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17542260, Length=172, Percent_Identity=31.3953488372093, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17542262, Length=114, Percent_Identity=36.8421052631579, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21356175, Length=177, Percent_Identity=32.2033898305085, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019918
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 44655; Mature: 44523

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHCCCCCCCCC
>Mature Secondary Structure 
SDSYFPRWRVQSTGAASRVVGPDERLAWPQMVAMGVQHVVAMFGSTVLAPLLMGFDPNL
CCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH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HHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]