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The map label for this gene is lrhA [H]

Identifier: 78067770

GI number: 78067770

Start: 3466172

End: 3467218

Strand: Reverse

Name: lrhA [H]

Synonym: Bcep18194_A6301

Alternate gene names: 78067770

Gene position: 3467218-3466172 (Counterclockwise)

Preceding gene: 78067772

Following gene: 78067769

Centisome position: 93.86

GC content: 73.35

Gene sequence:

>1047_bases
ATGTCAGGACAAGACATTCCGCGCGACGACGGCGAGTCGCTCGCGCTGGCCGATGCCACGCTGGCCCGGCCCAACTTCGA
CGTGGCGGCGCTGCGCAGTCTCGTCGCGGGGGTGGATCTCGGCAGTTTTGCGAAGGCGGCCGACCGCGTCGCGCGCTCGT
CGTCGGCGGTGAGCGCGCAGATCCGCAAGCTCGAGGAGCAGGCCGGCACGCCGCTGTTCGTGAAGTCCGGGCGCGGGCTC
GCGCTGACCGACGCTGGCGACGCGATGCTGCGCTATGCGCGGCGGATGATCGAGCTGAACGACGAGGCGGCCGCGGCCGT
GCGCGGCATGAATCTCGACGGCTGGGTGCGCGTCGGGCTGCAGGAGGATTTCGGCGAGGCGATCCTGCCCGATGTGCTCG
GGCGGTTCGCGCGCGCACATCCGAAGGTGCGGATCGAGGCACGCGTGGCGCGCAATGCCGACCTGCTCGACCGGCTGGAT
GCGAACCAGCTCGATCTCGCGCTGGTGTGGGGCGATCCGGCGTCGGCGGCGCTGGTGGCGCGCGCGGGGATCGAGAGCGA
AGCGATCGCGCAGGTGCCGATGCAGTGGGTCGGGGCAGCGGGTGGCTTCGGCATGCCGGGTGGCGGTGCGGAGGAGCGCG
TGGAAGGCGGAGCGGACGAAACGGGCGGCCGTGCGGTGCGCGTGCCGGGCGAGCCGCTGCCGCTCGTCGTGTTCGACCGG
CCGTGCCGGTTCTTCGGCGCGGCGACTGGCGCGCTCGATCGCGCAGGCGTGCCGTGGCGCGTCGCGTTCACGACACCGAG
TCTCGCCGGGCTATGGGCCGCGGCGGCAGCCGGCCTCGGGCTGACGGTGCGCTCGCAGTACGGGCTGCCCGCGTCGGTGC
GCGTGCTCGATGCGGCTTCGTGCGGGCTGCCGGCCCTGCCGAGTTTGCCGCTGATTTTGCTGCGACGCACGTCGTCGGCG
ACGCCGACCGTCGATCGGCTCGCGCGGATCGTGACGCAGGCGGTGCAGGATGCGACGGAGGGAGCGCGGGCGGCGCTGGC
GGCGTGA

Upstream 100 bases:

>100_bases
AGGCCCGGTTGGAAATTGACATCGACAGTCTGGCCACCTACATTCATCCTGAAAATCGGAAAGTTCTTGATGAATCGTTC
GATAAAACAGGATGGTTGAT

Downstream 100 bases:

>100_bases
CATCGATCGACACGTATGCGCTCGGCTGGACAATCGGCCTATTGGAGGAACGGAGCGAAGGTCGTGACAATGGTGGCTCA
CTCAATGGAGCCCATCATGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MSGQDIPRDDGESLALADATLARPNFDVAALRSLVAGVDLGSFAKAADRVARSSSAVSAQIRKLEEQAGTPLFVKSGRGL
ALTDAGDAMLRYARRMIELNDEAAAAVRGMNLDGWVRVGLQEDFGEAILPDVLGRFARAHPKVRIEARVARNADLLDRLD
ANQLDLALVWGDPASAALVARAGIESEAIAQVPMQWVGAAGGFGMPGGGAEERVEGGADETGGRAVRVPGEPLPLVVFDR
PCRFFGAATGALDRAGVPWRVAFTTPSLAGLWAAAAAGLGLTVRSQYGLPASVRVLDAASCGLPALPSLPLILLRRTSSA
TPTVDRLARIVTQAVQDATEGARAALAA

Sequences:

>Translated_348_residues
MSGQDIPRDDGESLALADATLARPNFDVAALRSLVAGVDLGSFAKAADRVARSSSAVSAQIRKLEEQAGTPLFVKSGRGL
ALTDAGDAMLRYARRMIELNDEAAAAVRGMNLDGWVRVGLQEDFGEAILPDVLGRFARAHPKVRIEARVARNADLLDRLD
ANQLDLALVWGDPASAALVARAGIESEAIAQVPMQWVGAAGGFGMPGGGAEERVEGGADETGGRAVRVPGEPLPLVVFDR
PCRFFGAATGALDRAGVPWRVAFTTPSLAGLWAAAAAGLGLTVRSQYGLPASVRVLDAASCGLPALPSLPLILLRRTSSA
TPTVDRLARIVTQAVQDATEGARAALAA
>Mature_347_residues
SGQDIPRDDGESLALADATLARPNFDVAALRSLVAGVDLGSFAKAADRVARSSSAVSAQIRKLEEQAGTPLFVKSGRGLA
LTDAGDAMLRYARRMIELNDEAAAAVRGMNLDGWVRVGLQEDFGEAILPDVLGRFARAHPKVRIEARVARNADLLDRLDA
NQLDLALVWGDPASAALVARAGIESEAIAQVPMQWVGAAGGFGMPGGGAEERVEGGADETGGRAVRVPGEPLPLVVFDRP
CRFFGAATGALDRAGVPWRVAFTTPSLAGLWAAAAAGLGLTVRSQYGLPASVRVLDAASCGLPALPSLPLILLRRTSSAT
PTVDRLARIVTQAVQDATEGARAALAA

Specific function: Not known, does not seem to act on the proton translocating NADH dehydrogenase genes (nuoA-N) which are part of the lrhA operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=313, Percent_Identity=33.2268370607029, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1790399, Length=268, Percent_Identity=28.3582089552239, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787806, Length=144, Percent_Identity=29.1666666666667, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI48994962, Length=147, Percent_Identity=29.9319727891156, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1787601, Length=144, Percent_Identity=25.6944444444444, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI157672245, Length=155, Percent_Identity=29.0322580645161, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790208, Length=152, Percent_Identity=27.6315789473684, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 36117; Mature: 35985

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGQDIPRDDGESLALADATLARPNFDVAALRSLVAGVDLGSFAKAADRVARSSSAVSAQ
CCCCCCCCCCCCEEEEEHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
IRKLEEQAGTPLFVKSGRGLALTDAGDAMLRYARRMIELNDEAAAAVRGMNLDGWVRVGL
HHHHHHHCCCEEEEECCCCEEEECCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEECC
QEDFGEAILPDVLGRFARAHPKVRIEARVARNADLLDRLDANQLDLALVWGDPASAALVA
HHHCCHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHCCCCCEEEEEEECCCCHHHHHH
RAGIESEAIAQVPMQWVGAAGGFGMPGGGAEERVEGGADETGGRAVRVPGEPLPLVVFDR
HCCCCHHHHHHCCHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCEEEECCCCCCEEEEECC
PCRFFGAATGALDRAGVPWRVAFTTPSLAGLWAAAAAGLGLTVRSQYGLPASVRVLDAAS
CHHHHHHHCCCHHCCCCCEEEEECCCCHHHHHHHHHHCCCEEEECCCCCCCEEEEEECCC
CGLPALPSLPLILLRRTSSATPTVDRLARIVTQAVQDATEGARAALAA
CCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SGQDIPRDDGESLALADATLARPNFDVAALRSLVAGVDLGSFAKAADRVARSSSAVSAQ
CCCCCCCCCCCEEEEEHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
IRKLEEQAGTPLFVKSGRGLALTDAGDAMLRYARRMIELNDEAAAAVRGMNLDGWVRVGL
HHHHHHHCCCEEEEECCCCEEEECCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEECC
QEDFGEAILPDVLGRFARAHPKVRIEARVARNADLLDRLDANQLDLALVWGDPASAALVA
HHHCCHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHCCCCCEEEEEEECCCCHHHHHH
RAGIESEAIAQVPMQWVGAAGGFGMPGGGAEERVEGGADETGGRAVRVPGEPLPLVVFDR
HCCCCHHHHHHCCHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCEEEECCCCCCEEEEECC
PCRFFGAATGALDRAGVPWRVAFTTPSLAGLWAAAAAGLGLTVRSQYGLPASVRVLDAAS
CHHHHHHHCCCHHCCCCCEEEEECCCCHHHHHHHHHHCCCEEEECCCCCCCEEEEEECCC
CGLPALPSLPLILLRRTSSATPTVDRLARIVTQAVQDATEGARAALAA
CCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]