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The map label for this gene is dapA [H]

Identifier: 78067767

GI number: 78067767

Start: 3464553

End: 3465446

Strand: Direct

Name: dapA [H]

Synonym: Bcep18194_A6298

Alternate gene names: 78067767

Gene position: 3464553-3465446 (Clockwise)

Preceding gene: 78067764

Following gene: 78067771

Centisome position: 93.79

GC content: 71.36

Gene sequence:

>894_bases
ATGAACACACGTTTCGAAGGTATCTGGCTGCCGATCATCACGCCGTTCCACCACGGCGAAGTCGACCATGCCGCGCTCGC
GCGACTCGCGCGCCACTATGCGGCCGCGGGCATCGCCGGTTTCGTCGCGGGCGCGACGACTGGTGAAGGCGTGCTGCTCG
ACGCGCGCGAACAGGACGCGGTGTTCGCGACGCTGCGCGACGCGGCGCCCGGGCTGCCGATCGTCGTCGGGCTGACCGCG
AGCGCGACGCATTTCGCGGCCGCCCGCGCGCGCGAACTCGCGGCGTTGCGGCCCGACGGGCTGCTCGTCACGCCGCCCGT
CTACGTGCGGCCGACGCAGGACGGCATCCGCCGCCACGTCGAGGCGATCGTCGACGCGGCCGACCTGCCGGTGCTCGTCT
ACAACATCCCGTACCGCACCGGCGTGAACGTCGAACTGGAGACGCTGCAGGCGCTTGCGCGCGACCCGCGCGTCGCGGGC
ATCAAGGAATGCGGCGGGTCGCTCGACCGGATGAGCCGGCTCGTGCACGACACGCCGCTCGCGATCCTGTCCGGCGACGA
CAACCAGAACTTCGCAGCGATGTGCACCGGTGCGCACGGCGCGATCGCGAGCAGCGCGCACGTGCTGCCCGAATGGCATG
TGCGCATCCATGCACTGCTGCGCGACGGGCGGCTCGCCGATGCAAGGCGCCTGTCGGTCGCGCTGCAGCCGCTCGTCGCG
GCGCTGTTCGCGGAGCCGAACCCGGCGCCGGTGAAGGCCGTGCTGGCCGCGCAAGGGTGGTGCGAGGACGGTTTGCGACT
GCCGTTCGTGCCGGCGAGTGAAGGGTTGAGGGCGCGGCTGGCGGCCATTTGTGCGGAACTGGAAACGCCCACGCAAGCTG
TCGCGGCAGCGTAG

Upstream 100 bases:

>100_bases
TGCCCGCAGGTCGTTTCTTTCTCCTTGCTCGCACGCCTCGCTCCGGCTCTCCGCCGGCGGAACGGTTCCTTCCCACTCCG
TTTCCACCATGAGGCTTTGC

Downstream 100 bases:

>100_bases
GATCTCGCTCCCGAAACTGTTTCAGACTGTCAGTATTCGGGACGCGCCATACTGCGCGAGGTGGCTGTCTGCCGTGACGA
GCAGCAGCGGTTCACACCAC

Product: dihydrodipicolinate synthase subfamily protein

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MNTRFEGIWLPIITPFHHGEVDHAALARLARHYAAAGIAGFVAGATTGEGVLLDAREQDAVFATLRDAAPGLPIVVGLTA
SATHFAAARARELAALRPDGLLVTPPVYVRPTQDGIRRHVEAIVDAADLPVLVYNIPYRTGVNVELETLQALARDPRVAG
IKECGGSLDRMSRLVHDTPLAILSGDDNQNFAAMCTGAHGAIASSAHVLPEWHVRIHALLRDGRLADARRLSVALQPLVA
ALFAEPNPAPVKAVLAAQGWCEDGLRLPFVPASEGLRARLAAICAELETPTQAVAAA

Sequences:

>Translated_297_residues
MNTRFEGIWLPIITPFHHGEVDHAALARLARHYAAAGIAGFVAGATTGEGVLLDAREQDAVFATLRDAAPGLPIVVGLTA
SATHFAAARARELAALRPDGLLVTPPVYVRPTQDGIRRHVEAIVDAADLPVLVYNIPYRTGVNVELETLQALARDPRVAG
IKECGGSLDRMSRLVHDTPLAILSGDDNQNFAAMCTGAHGAIASSAHVLPEWHVRIHALLRDGRLADARRLSVALQPLVA
ALFAEPNPAPVKAVLAAQGWCEDGLRLPFVPASEGLRARLAAICAELETPTQAVAAA
>Mature_297_residues
MNTRFEGIWLPIITPFHHGEVDHAALARLARHYAAAGIAGFVAGATTGEGVLLDAREQDAVFATLRDAAPGLPIVVGLTA
SATHFAAARARELAALRPDGLLVTPPVYVRPTQDGIRRHVEAIVDAADLPVLVYNIPYRTGVNVELETLQALARDPRVAG
IKECGGSLDRMSRLVHDTPLAILSGDDNQNFAAMCTGAHGAIASSAHVLPEWHVRIHALLRDGRLADARRLSVALQPLVA
ALFAEPNPAPVKAVLAAQGWCEDGLRLPFVPASEGLRARLAAICAELETPTQAVAAA

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=232, Percent_Identity=26.2931034482759, Blast_Score=89, Evalue=4e-18,
Organism=Escherichia coli, GI1788823, Length=284, Percent_Identity=35.9154929577465, Blast_Score=154, Evalue=5e-39,
Organism=Escherichia coli, GI1789620, Length=295, Percent_Identity=27.4576271186441, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87082415, Length=253, Percent_Identity=26.8774703557312, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1786463, Length=233, Percent_Identity=26.6094420600858, Blast_Score=81, Evalue=9e-17,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 31387; Mature: 31387

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTRFEGIWLPIITPFHHGEVDHAALARLARHYAAAGIAGFVAGATTGEGVLLDAREQDA
CCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCH
VFATLRDAAPGLPIVVGLTASATHFAAARARELAALRPDGLLVTPPVYVRPTQDGIRRHV
HEEEHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCEEECCCEEEECCHHHHHHHH
EAIVDAADLPVLVYNIPYRTGVNVELETLQALARDPRVAGIKECGGSLDRMSRLVHDTPL
HHHHHHCCCCEEEEECCCCCCCCEEHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHCCCE
AILSGDDNQNFAAMCTGAHGAIASSAHVLPEWHVRIHALLRDGRLADARRLSVALQPLVA
EEEECCCCCCEEEEEECCCCCCCCCCCCCCHHHHHEEEHHHCCCCCHHHHHHHHHHHHHH
ALFAEPNPAPVKAVLAAQGWCEDGLRLPFVPASEGLRARLAAICAELETPTQAVAAA
HHHCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHCC
>Mature Secondary Structure
MNTRFEGIWLPIITPFHHGEVDHAALARLARHYAAAGIAGFVAGATTGEGVLLDAREQDA
CCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCH
VFATLRDAAPGLPIVVGLTASATHFAAARARELAALRPDGLLVTPPVYVRPTQDGIRRHV
HEEEHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCEEECCCEEEECCHHHHHHHH
EAIVDAADLPVLVYNIPYRTGVNVELETLQALARDPRVAGIKECGGSLDRMSRLVHDTPL
HHHHHHCCCCEEEEECCCCCCCCEEHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHCCCE
AILSGDDNQNFAAMCTGAHGAIASSAHVLPEWHVRIHALLRDGRLADARRLSVALQPLVA
EEEECCCCCCEEEEEECCCCCCCCCCCCCCHHHHHEEEHHHCCCCCHHHHHHHHHHHHHH
ALFAEPNPAPVKAVLAAQGWCEDGLRLPFVPASEGLRARLAAICAELETPTQAVAAA
HHHCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA