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The map label for this gene is yjcC [H]

Identifier: 78067759

GI number: 78067759

Start: 3451250

End: 3452536

Strand: Reverse

Name: yjcC [H]

Synonym: Bcep18194_A6290

Alternate gene names: 78067759

Gene position: 3452536-3451250 (Counterclockwise)

Preceding gene: 78067761

Following gene: 78067758

Centisome position: 93.46

GC content: 71.64

Gene sequence:

>1287_bases
ATGACGATCGTGCAACAGGAGCGTCCGGCCGCCGCGTCGCCGTACCGGTTCGAGCGGGAGGTGAGTTCCGGCTTCGAACG
TCTGGCGACGCAGCACCGCGACCTGACGCTCACGACCGTGTTCCAGCCGATATTCAGCCTGTCGCACCAGCGTGCGGTGG
GCTACGAGGCGCTGCTGCGCGCGCACGATGCGCTCGACCGCGCCGTGTCGCCGCTCGACGTGTTCGGCGAAGCCGCGCGC
CAGGGCGAGCTGCTGCAGCTCGACCGGCTCGCGCAGGCGCTGCATCTCGAGAACTTCGCGCTGCTCGGCGCGGAGCGCGA
ATGGCTGTTCCTCAACGTCCATCCGGGCGTGCTCACCGACCCGTTCCAGGCGGCCGCGCTGCTCGCGAACCTGAAGCGGC
TCGGCATGCCGCCGCGCCGCATCGTGCTCGAAGTGCTCGAACAGCGCGCGGAAGACGTCGAGCGGCTTGCCGAGGCCGTG
CGCGAATTCCGCACGCACGGTTTCCTGATCGCGCTCGACGATTTCGGCGCGGGTCACTCGAACCTCGAGCGGATCTGGCA
GCTGAACCCGGACATCGTGAAGCTCGACCGGATCATGCTGTCGCACGCAGCGCACCGCACCGGGCTCACCGCGATCCTGC
ACGGGCTCGTGACGCTGCTGCACGAGGCCGGCAAGCTGGTGCTCGTCGAGGGCATCGAGACCGAGCACGAGGCGCAGATC
GCGCTGTCGTGCGAGGCCGATTTCGTACAGGGCTACTACTTCGGCCGGCCGGCGCCGGGGCTGCCCGACAGCGCGGCCGC
GACGGGCTGCATCGGCGAGCTGACCGAGCGTTTTCGGCAGCAGACCGACGCGCGCGAGCGGCGCGATGCGCAGCGGATCG
CGCCGTACCTGCGCGCGTTCGAACGCGCGGCCGAGCGTCTCGCGGCCGGCGAGCCGCTCGACGAGGTGTGCTGGAACTTC
CTCGCGCTCGACGCGGCCGCGCGCTGCTTCCTGCTCGACGCGCACGGCCGCCAGTCGGGCCGCAACGTCGTGCTGCGCGC
CGACCGCGCGCTCGCCGAGGCGCGCTTCTCGCCGCTGGCGGACGCGCAGGGCGCGAACTGGCTGCGCCGGCCGTATTTCC
GCTCGGCGATCGCCGAGCCGGGGCGCGTGCAGGTCACGCGGCCGTACCTGTCGATCAACGAGGCGCAGCCGTGCGTGACG
CTGTCGGTGGCCGTGCGGGTCGGCGATGCGCAGCGCGTGCTGTGCGGCGATATCGACTGGCGCGACGACGAAGCGGACGC
CGGCTAG

Upstream 100 bases:

>100_bases
CGTCCGGCGCCGACCGGGCAACCGAGGGTCCAACCATGACATTGCACGCGCCGCTCGCTTCGTCGGGCGCCGCGTTCGAA
GGCAATACCAGGAGGAAGGC

Downstream 100 bases:

>100_bases
CGCCGCGCGCACCGCAGGCGGCGGACGGCGCGAGCGGCGCGGGCCGTCCGTTGCGTTCGCCGTGCGCTTCCCCGACAATG
GCCCGACTGCGGCCATCGTG

Product: diguanylate phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MTIVQQERPAAASPYRFEREVSSGFERLATQHRDLTLTTVFQPIFSLSHQRAVGYEALLRAHDALDRAVSPLDVFGEAAR
QGELLQLDRLAQALHLENFALLGAEREWLFLNVHPGVLTDPFQAAALLANLKRLGMPPRRIVLEVLEQRAEDVERLAEAV
REFRTHGFLIALDDFGAGHSNLERIWQLNPDIVKLDRIMLSHAAHRTGLTAILHGLVTLLHEAGKLVLVEGIETEHEAQI
ALSCEADFVQGYYFGRPAPGLPDSAAATGCIGELTERFRQQTDARERRDAQRIAPYLRAFERAAERLAAGEPLDEVCWNF
LALDAAARCFLLDAHGRQSGRNVVLRADRALAEARFSPLADAQGANWLRRPYFRSAIAEPGRVQVTRPYLSINEAQPCVT
LSVAVRVGDAQRVLCGDIDWRDDEADAG

Sequences:

>Translated_428_residues
MTIVQQERPAAASPYRFEREVSSGFERLATQHRDLTLTTVFQPIFSLSHQRAVGYEALLRAHDALDRAVSPLDVFGEAAR
QGELLQLDRLAQALHLENFALLGAEREWLFLNVHPGVLTDPFQAAALLANLKRLGMPPRRIVLEVLEQRAEDVERLAEAV
REFRTHGFLIALDDFGAGHSNLERIWQLNPDIVKLDRIMLSHAAHRTGLTAILHGLVTLLHEAGKLVLVEGIETEHEAQI
ALSCEADFVQGYYFGRPAPGLPDSAAATGCIGELTERFRQQTDARERRDAQRIAPYLRAFERAAERLAAGEPLDEVCWNF
LALDAAARCFLLDAHGRQSGRNVVLRADRALAEARFSPLADAQGANWLRRPYFRSAIAEPGRVQVTRPYLSINEAQPCVT
LSVAVRVGDAQRVLCGDIDWRDDEADAG
>Mature_427_residues
TIVQQERPAAASPYRFEREVSSGFERLATQHRDLTLTTVFQPIFSLSHQRAVGYEALLRAHDALDRAVSPLDVFGEAARQ
GELLQLDRLAQALHLENFALLGAEREWLFLNVHPGVLTDPFQAAALLANLKRLGMPPRRIVLEVLEQRAEDVERLAEAVR
EFRTHGFLIALDDFGAGHSNLERIWQLNPDIVKLDRIMLSHAAHRTGLTAILHGLVTLLHEAGKLVLVEGIETEHEAQIA
LSCEADFVQGYYFGRPAPGLPDSAAATGCIGELTERFRQQTDARERRDAQRIAPYLRAFERAAERLAAGEPLDEVCWNFL
ALDAAARCFLLDAHGRQSGRNVVLRADRALAEARFSPLADAQGANWLRRPYFRSAIAEPGRVQVTRPYLSINEAQPCVTL
SVAVRVGDAQRVLCGDIDWRDDEADAG

Specific function: Overexpression reduces biofilm formation [H]

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1790496, Length=231, Percent_Identity=26.8398268398268, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI87082096, Length=151, Percent_Identity=31.1258278145695, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787055, Length=232, Percent_Identity=28.448275862069, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081743, Length=256, Percent_Identity=28.90625, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081921, Length=233, Percent_Identity=24.8927038626609, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788502, Length=232, Percent_Identity=27.5862068965517, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI87081980, Length=258, Percent_Identity=25.968992248062, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786507, Length=226, Percent_Identity=26.1061946902655, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI87081845, Length=120, Percent_Identity=32.5, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788849, Length=216, Percent_Identity=26.8518518518519, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI226510982, Length=155, Percent_Identity=28.3870967741935, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 47624; Mature: 47492

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIVQQERPAAASPYRFEREVSSGFERLATQHRDLTLTTVFQPIFSLSHQRAVGYEALLR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AHDALDRAVSPLDVFGEAARQGELLQLDRLAQALHLENFALLGAEREWLFLNVHPGVLTD
HHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEECCCCCEEEEEECCCCCCC
PFQAAALLANLKRLGMPPRRIVLEVLEQRAEDVERLAEAVREFRTHGFLIALDDFGAGHS
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHH
NLERIWQLNPDIVKLDRIMLSHAAHRTGLTAILHGLVTLLHEAGKLVLVEGIETEHEAQI
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEE
ALSCEADFVQGYYFGRPAPGLPDSAAATGCIGELTERFRQQTDARERRDAQRIAPYLRAF
EEEECHHHHHCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERAAERLAAGEPLDEVCWNFLALDAAARCFLLDAHGRQSGRNVVLRADRALAEARFSPLA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEEEECHHHHHHHHCCCCC
DAQGANWLRRPYFRSAIAEPGRVQVTRPYLSINEAQPCVTLSVAVRVGDAQRVLCGDIDW
CCCCCCHHHHHHHHHHHCCCCCEEEECCCEECCCCCCEEEEEEEEEECCCCEEEECCCCC
RDDEADAG
CCCCCCCC
>Mature Secondary Structure 
TIVQQERPAAASPYRFEREVSSGFERLATQHRDLTLTTVFQPIFSLSHQRAVGYEALLR
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AHDALDRAVSPLDVFGEAARQGELLQLDRLAQALHLENFALLGAEREWLFLNVHPGVLTD
HHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEECCCCCEEEEEECCCCCCC
PFQAAALLANLKRLGMPPRRIVLEVLEQRAEDVERLAEAVREFRTHGFLIALDDFGAGHS
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHH
NLERIWQLNPDIVKLDRIMLSHAAHRTGLTAILHGLVTLLHEAGKLVLVEGIETEHEAQI
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEE
ALSCEADFVQGYYFGRPAPGLPDSAAATGCIGELTERFRQQTDARERRDAQRIAPYLRAF
EEEECHHHHHCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERAAERLAAGEPLDEVCWNFLALDAAARCFLLDAHGRQSGRNVVLRADRALAEARFSPLA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEEEECHHHHHHHHCCCCC
DAQGANWLRRPYFRSAIAEPGRVQVTRPYLSINEAQPCVTLSVAVRVGDAQRVLCGDIDW
CCCCCCHHHHHHHHHHHCCCCCEEEECCCEECCCCCCEEEEEEEEEECCCCEEEECCCCC
RDDEADAG
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]