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The map label for this gene is paaG [C]

Identifier: 78067723

GI number: 78067723

Start: 3411547

End: 3412374

Strand: Reverse

Name: paaG [C]

Synonym: Bcep18194_A6254

Alternate gene names: 78067723

Gene position: 3412374-3411547 (Counterclockwise)

Preceding gene: 78067724

Following gene: 78067722

Centisome position: 92.37

GC content: 69.81

Gene sequence:

>828_bases
ATGGCCAATCTCGCCGCGTACGGCGGTTACGAAGCACTGAAGGTGACGCGCCGCGATCATGGCGTGCTCGACATCGTGAT
GAGCGGCGAGGGCACGAACCGCAGCGGCCTCGCGACCGCGAACGCGCGCATGCATCGCGAGCTCGCCGACATCTGGCGCG
ACGTCGACCGCGATCCCGACACGCGCGTCGCGGTGATCCGTGGCGAAGGCAAGGGCTTCTCGGCGGGCGGCGATCTCGCG
CTCGTCGAGGACATGGCGAACGACTTCGACGTGCGCGCCCGCGTGTGGCGCGAGGCGCGCGACCTCGTCTACAACGTGAT
CAACTGCAGCAAGCCGATCGTCTCGGCGATGCATGGCCCGGCCGTCGGCGCGGGGCTCGTCGCCGGGCTGCTCGCGGACA
TCTCGATCGCCGCGAAGGATGCACGCATCATCGACGGCCACACGCGGCTCGGCGTCGCGGCAGGCGACCACGCGGCGATC
GTGTGGCCGCTGCTGTGCGGGATGGCGAAGGCGAAGTACTACCTGATGCTGTGCGAGCCGGTGAGCGGCGAGGAGGCCGA
GCGGATCGGGCTGGTATCGCTCGCGGTCGAGCCGGCCGACCTGCTGCCGAAGGCCTACGAAGTGGCCGAGCGGCTCGCGC
ACGGTTCGCAGTCGGCGATCCGCTGGACCAAGTACGCATTGAACAACTGGCTGCGCACGGCCGGGCCGACCTTCGATACG
TCGCTCGCGCTCGAATTCATGGGGTTTGCCGGGCCCGACGTGCAGGAAGGCATCCGCTCGCTGCGCGAGCGCCGTCCGCC
CGAGTTCCCCGGCGACGCGCCGTTCTGA

Upstream 100 bases:

>100_bases
CCGGGCCCGGCCCGCGCGCCGGGTTTCGCCTGATGTTTGCCCGCGCGGGCTTGGCTACACTCGATTCAGGGGCGCGAGAG
CCTCGAGCAAGGAGCAGCGC

Downstream 100 bases:

>100_bases
CACGCGCTGGCGCTATGATCGATCCAGGCGCGGCTCGCGCGATGCATGGCGGCCGCCTCGTTCTCACCCAGTCAACCAGG
ACGCCCGTATGACGACCGAT

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MANLAAYGGYEALKVTRRDHGVLDIVMSGEGTNRSGLATANARMHRELADIWRDVDRDPDTRVAVIRGEGKGFSAGGDLA
LVEDMANDFDVRARVWREARDLVYNVINCSKPIVSAMHGPAVGAGLVAGLLADISIAAKDARIIDGHTRLGVAAGDHAAI
VWPLLCGMAKAKYYLMLCEPVSGEEAERIGLVSLAVEPADLLPKAYEVAERLAHGSQSAIRWTKYALNNWLRTAGPTFDT
SLALEFMGFAGPDVQEGIRSLRERRPPEFPGDAPF

Sequences:

>Translated_275_residues
MANLAAYGGYEALKVTRRDHGVLDIVMSGEGTNRSGLATANARMHRELADIWRDVDRDPDTRVAVIRGEGKGFSAGGDLA
LVEDMANDFDVRARVWREARDLVYNVINCSKPIVSAMHGPAVGAGLVAGLLADISIAAKDARIIDGHTRLGVAAGDHAAI
VWPLLCGMAKAKYYLMLCEPVSGEEAERIGLVSLAVEPADLLPKAYEVAERLAHGSQSAIRWTKYALNNWLRTAGPTFDT
SLALEFMGFAGPDVQEGIRSLRERRPPEFPGDAPF
>Mature_274_residues
ANLAAYGGYEALKVTRRDHGVLDIVMSGEGTNRSGLATANARMHRELADIWRDVDRDPDTRVAVIRGEGKGFSAGGDLAL
VEDMANDFDVRARVWREARDLVYNVINCSKPIVSAMHGPAVGAGLVAGLLADISIAAKDARIIDGHTRLGVAAGDHAAIV
WPLLCGMAKAKYYLMLCEPVSGEEAERIGLVSLAVEPADLLPKAYEVAERLAHGSQSAIRWTKYALNNWLRTAGPTFDTS
LALEFMGFAGPDVQEGIRSLRERRPPEFPGDAPF

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI70995211, Length=159, Percent_Identity=34.5911949685535, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI194097323, Length=226, Percent_Identity=23.8938053097345, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787660, Length=241, Percent_Identity=30.7053941908714, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1787659, Length=222, Percent_Identity=31.5315315315315, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI221142681, Length=212, Percent_Identity=29.2452830188679, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788597, Length=263, Percent_Identity=23.9543726235741, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17534483, Length=230, Percent_Identity=28.2608695652174, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI25145438, Length=229, Percent_Identity=27.0742358078603, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17554946, Length=237, Percent_Identity=26.5822784810127, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17540714, Length=216, Percent_Identity=25.9259259259259, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17535521, Length=196, Percent_Identity=26.0204081632653, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17540306, Length=258, Percent_Identity=25.1937984496124, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17536985, Length=209, Percent_Identity=26.7942583732057, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24653139, Length=286, Percent_Identity=26.9230769230769, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24654903, Length=200, Percent_Identity=24.5, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI20129971, Length=238, Percent_Identity=25.2100840336134, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24653477, Length=238, Percent_Identity=25.2100840336134, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI19922422, Length=262, Percent_Identity=25.1908396946565, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 29683; Mature: 29552

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANLAAYGGYEALKVTRRDHGVLDIVMSGEGTNRSGLATANARMHRELADIWRDVDRDPD
CCCCCCCCCHHHEEEECCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
TRVAVIRGEGKGFSAGGDLALVEDMANDFDVRARVWREARDLVYNVINCSKPIVSAMHGP
CEEEEEEECCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCC
AVGAGLVAGLLADISIAAKDARIIDGHTRLGVAAGDHAAIVWPLLCGMAKAKYYLMLCEP
CHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEECCCCHHHHHHHHHHHHHCEEEEEEECC
VSGEEAERIGLVSLAVEPADLLPKAYEVAERLAHGSQSAIRWTKYALNNWLRTAGPTFDT
CCCCCHHHEEEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCH
SLALEFMGFAGPDVQEGIRSLRERRPPEFPGDAPF
HHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
ANLAAYGGYEALKVTRRDHGVLDIVMSGEGTNRSGLATANARMHRELADIWRDVDRDPD
CCCCCCCCHHHEEEECCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
TRVAVIRGEGKGFSAGGDLALVEDMANDFDVRARVWREARDLVYNVINCSKPIVSAMHGP
CEEEEEEECCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCC
AVGAGLVAGLLADISIAAKDARIIDGHTRLGVAAGDHAAIVWPLLCGMAKAKYYLMLCEP
CHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEECCCCHHHHHHHHHHHHHCEEEEEEECC
VSGEEAERIGLVSLAVEPADLLPKAYEVAERLAHGSQSAIRWTKYALNNWLRTAGPTFDT
CCCCCHHHEEEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCH
SLALEFMGFAGPDVQEGIRSLRERRPPEFPGDAPF
HHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA