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The map label for this gene is fabF [H]

Identifier: 78067565

GI number: 78067565

Start: 3240606

End: 3241817

Strand: Direct

Name: fabF [H]

Synonym: Bcep18194_A6096

Alternate gene names: 78067565

Gene position: 3240606-3241817 (Clockwise)

Preceding gene: 78067564

Following gene: 78067566

Centisome position: 87.72

GC content: 71.12

Gene sequence:

>1212_bases
GTGAAACCTCTCCTGCTCTCGCACTTCACCGCCACCAGCTGCATCGGCCGCGGCCTCGATGCGACCCTCGATGCGCTGCG
CCACGCGCGCGGCGGGCTCCAGCCCTGCGACTTCGAGCATGCGGATCTCGACACGTGGATCGGCGCGGTGGACGGCGTCG
ATGCGCAGCCCGTGCGGGCCGACCTCGCCGACTTCGCGTGCCGCAACAACCGCCTCGCGCAGCTCGGCCTCACGCAGGAC
AACTTCGACGCACGCGTCGCGGCGGCTGTCGCGCGCTACGGTGCAGCGCGCGTCGGTGTGTTCATCGGCACGAGCACGGC
CGGCATCCTCGAAACCGAGCACGCCTATCAGCGCCGCGATCCGGCAAGCGGCGCGCTGCCTGCCGACTTCCGCTACGCGC
ACACGCACAACCCGTATTCGCCGGCCGCATTCGTGCGCGCGTTTCTCGCGCTGCGCGGGCCGGCGATGGCGATCTCGTCC
GCCTGCTCGTCCGGCGCGAAGGTGTTCGGCTCCGCGCGCCGCATGATCGAGGCAGGCTTGATCGACGCGGCCGTCGTCGG
CGGCGTCGATTCGTTGTGCCTGACGACGCTGTACGGCTTCAATTCGCTCGAACTGCTGTCGCGCCAGCCGTGCCGTCCGT
TCGACGTCGCGCGCGACGGTATCTCGATCGGCGAGGCCGCCGCGTTCGCGCTCGTCGAACGCGTGCCCGACTCGCCCGCC
GCACTCGACGCCCACGCGATCCTGCTGCTCGGCATCGGCGAATCGAGCGACGCGCATCACATGTCGTCGCCGCATCCGGA
CGGGCTCGGCGCGCGCGTCGCGATCGAGCAGGCGCTCACGGCCGCCAGTCTCGGCGCGAACGATATCGACTACGTGAACC
TGCACGGCACCGCGACGCCGAGCAACGACGCGGCCGAAAGCCGCGCGATCGGCGCGCTGTTTGCCAGCACGCCGTGCAGT
TCGACGAAGGGCGCGACCGGCCATACGCTCGGCGCGGCGGGTGCGCTCGAGGCGGTCGTCGCCGCGCTCGCGCTGCGCGA
GCAGTTCGTGCCGGCCGGCGTCAACACGACGCAACCCGACCCGGCACTCGCCGCCGACTACGTACTCGCAAGCCGCGATG
CGCGCGTGCGTGCCGTCCTCTCCAATTCGTTCGGCTTCGGCGGCACGAATTGCAGCCTGATCCTCGGCCGCGCCGACCAC
GCACGCCGTTGA

Upstream 100 bases:

>100_bases
GCCGGCCGGCTCGGCCCACCCGTTTGATAAAATCTGACTTCGAGCGGCGCGCCTGCCAGCCCTGCTGCGGCGCCCGTTCC
GGCCACCGGATGCGACCCTC

Downstream 100 bases:

>100_bases
GGCCCGCCATGACACTCACCGCCTTCATCGAAAGCATCGGCCTGATCGGCCCCGGATTGACCGACTGGCCGCACGCGGCC
GACGTGCTCGCGGGCCACGC

Product: 3-oxoacyl-(acyl carrier protein) synthase I

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MKPLLLSHFTATSCIGRGLDATLDALRHARGGLQPCDFEHADLDTWIGAVDGVDAQPVRADLADFACRNNRLAQLGLTQD
NFDARVAAAVARYGAARVGVFIGTSTAGILETEHAYQRRDPASGALPADFRYAHTHNPYSPAAFVRAFLALRGPAMAISS
ACSSGAKVFGSARRMIEAGLIDAAVVGGVDSLCLTTLYGFNSLELLSRQPCRPFDVARDGISIGEAAAFALVERVPDSPA
ALDAHAILLLGIGESSDAHHMSSPHPDGLGARVAIEQALTAASLGANDIDYVNLHGTATPSNDAAESRAIGALFASTPCS
STKGATGHTLGAAGALEAVVAALALREQFVPAGVNTTQPDPALAADYVLASRDARVRAVLSNSFGFGGTNCSLILGRADH
ARR

Sequences:

>Translated_403_residues
MKPLLLSHFTATSCIGRGLDATLDALRHARGGLQPCDFEHADLDTWIGAVDGVDAQPVRADLADFACRNNRLAQLGLTQD
NFDARVAAAVARYGAARVGVFIGTSTAGILETEHAYQRRDPASGALPADFRYAHTHNPYSPAAFVRAFLALRGPAMAISS
ACSSGAKVFGSARRMIEAGLIDAAVVGGVDSLCLTTLYGFNSLELLSRQPCRPFDVARDGISIGEAAAFALVERVPDSPA
ALDAHAILLLGIGESSDAHHMSSPHPDGLGARVAIEQALTAASLGANDIDYVNLHGTATPSNDAAESRAIGALFASTPCS
STKGATGHTLGAAGALEAVVAALALREQFVPAGVNTTQPDPALAADYVLASRDARVRAVLSNSFGFGGTNCSLILGRADH
ARR
>Mature_403_residues
MKPLLLSHFTATSCIGRGLDATLDALRHARGGLQPCDFEHADLDTWIGAVDGVDAQPVRADLADFACRNNRLAQLGLTQD
NFDARVAAAVARYGAARVGVFIGTSTAGILETEHAYQRRDPASGALPADFRYAHTHNPYSPAAFVRAFLALRGPAMAISS
ACSSGAKVFGSARRMIEAGLIDAAVVGGVDSLCLTTLYGFNSLELLSRQPCRPFDVARDGISIGEAAAFALVERVPDSPA
ALDAHAILLLGIGESSDAHHMSSPHPDGLGARVAIEQALTAASLGANDIDYVNLHGTATPSNDAAESRAIGALFASTPCS
STKGATGHTLGAAGALEAVVAALALREQFVPAGVNTTQPDPALAADYVLASRDARVRAVLSNSFGFGGTNCSLILGRADH
ARR

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthes

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=260, Percent_Identity=40, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI223972627, Length=147, Percent_Identity=42.8571428571429, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI41872631, Length=264, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1787337, Length=269, Percent_Identity=39.0334572490706, Blast_Score=151, Evalue=8e-38,
Organism=Escherichia coli, GI1788663, Length=258, Percent_Identity=34.1085271317829, Blast_Score=122, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI71983541, Length=268, Percent_Identity=34.7014925373134, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI71983535, Length=258, Percent_Identity=34.8837209302326, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI212642053, Length=332, Percent_Identity=26.8072289156627, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17550940, Length=309, Percent_Identity=25.2427184466019, Blast_Score=82, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6320904, Length=269, Percent_Identity=36.8029739776952, Blast_Score=129, Evalue=8e-31,
Organism=Drosophila melanogaster, GI24644341, Length=263, Percent_Identity=41.06463878327, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24581345, Length=332, Percent_Identity=26.2048192771084, Blast_Score=95, Evalue=7e-20,
Organism=Drosophila melanogaster, GI221330659, Length=327, Percent_Identity=26.605504587156, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19920632, Length=327, Percent_Identity=26.605504587156, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 41693; Mature: 41693

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPLLLSHFTATSCIGRGLDATLDALRHARGGLQPCDFEHADLDTWIGAVDGVDAQPVRA
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCCHHH
DLADFACRNNRLAQLGLTQDNFDARVAAAVARYGAARVGVFIGTSTAGILETEHAYQRRD
HHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHCC
PASGALPADFRYAHTHNPYSPAAFVRAFLALRGPAMAISSACSSGAKVFGSARRMIEAGL
CCCCCCCCCCEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDAAVVGGVDSLCLTTLYGFNSLELLSRQPCRPFDVARDGISIGEAAAFALVERVPDSPA
HHHHHHCCHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCC
ALDAHAILLLGIGESSDAHHMSSPHPDGLGARVAIEQALTAASLGANDIDYVNLHGTATP
CCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCC
SNDAAESRAIGALFASTPCSSTKGATGHTLGAAGALEAVVAALALREQFVPAGVNTTQPD
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PALAADYVLASRDARVRAVLSNSFGFGGTNCSLILGRADHARR
CHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MKPLLLSHFTATSCIGRGLDATLDALRHARGGLQPCDFEHADLDTWIGAVDGVDAQPVRA
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCCHHH
DLADFACRNNRLAQLGLTQDNFDARVAAAVARYGAARVGVFIGTSTAGILETEHAYQRRD
HHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHCC
PASGALPADFRYAHTHNPYSPAAFVRAFLALRGPAMAISSACSSGAKVFGSARRMIEAGL
CCCCCCCCCCEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDAAVVGGVDSLCLTTLYGFNSLELLSRQPCRPFDVARDGISIGEAAAFALVERVPDSPA
HHHHHHCCHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCC
ALDAHAILLLGIGESSDAHHMSSPHPDGLGARVAIEQALTAASLGANDIDYVNLHGTATP
CCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCC
SNDAAESRAIGALFASTPCSSTKGATGHTLGAAGALEAVVAALALREQFVPAGVNTTQPD
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PALAADYVLASRDARVRAVLSNSFGFGGTNCSLILGRADHARR
CHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12704232 [H]