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The map label for this gene is ywlC [H]

Identifier: 78067422

GI number: 78067422

Start: 3082379

End: 3083407

Strand: Reverse

Name: ywlC [H]

Synonym: Bcep18194_A5953

Alternate gene names: 78067422

Gene position: 3083407-3082379 (Counterclockwise)

Preceding gene: 78067423

Following gene: 78067418

Centisome position: 83.47

GC content: 72.89

Gene sequence:

>1029_bases
ATGTCCATCGATCTTCCGAACTCCGTGACGGCCGCGCAGATCGACGCGGCCGCCGCGCTGCTCGATGCGGGCCAGCTCGT
CGCCTTTCCGACCGAAACCGTCTACGGGCTCGGCGGTGACGCGGCGAACCCCGAGGCCGTCGCGCGCATCTACGCGGCGA
AGGGGCGGCCCGCGAATCATCCGGTGATCGTGCACCTGCCGCCGGGCGGCGATCCTGGCTACTGGGCCGACGATCTGCCG
GCCGACGCGCAGGCGTTGATCGATGCGTTCTGGCCGGGCCCGCTGACGCTGATCCTGAAGCGCCATGCGCGCATTCCGGA
CGCCGTGAGCGGCGGCCAGGATTCGGTCGGGCTGCGCTGCCCGTCGCATCCGGTCGCGCAGGCGCTGCTGGCCGCGTTCA
GCGCGCGGCGCGGCGGGCACGGCGGCGTGGCTGCGCCGTCCGCTAACCGGTTCGGCCATGTGAGCCCGACCACCGCGCAG
CATGTGCGCGACGAATTCGGCGACACCGTGCACGTGCTGGACGGCGGTGCATCGGAGGTCGGTATCGAATCGACGATTCT
CGACCTGTCGCGCGGCTTCCCGGCGCTGCTGCGCCCGGGCCACGTGACGCCGCAGCAGATTGCCGATGTGCTCGGCCGCG
CACCGCGGCTGCCGGACGGCAGCGACGCGACCGCGCCGCGCGCGTCCGGCACGCTGAAAGCACATTACGCGCCGCGCACG
CCGCTTGCGCTGCTGCCGTTCGACGCGCTCGAGCCGCTGCTCGCGGCCGCGCAGACCGACGGCGAGCGGGTTGCGCTCGT
CGCACGCGCGTCGCGCGCGGGACGCTGGGCGCAGGCCGACGGCGTGCATTTCGTCGCGGCGCCGGAAGATCCGCAGGCGT
ATGCGCGCGACCTGTACGGGATGCTGCGTGCGCTCGACCGCGCGCAGGTCGCGCGGATTCTCGTCGAGAAGCTGCCCGAG
ACCGTCGAGTGGATTGCCGTCAACGATCGTCTCGGCCGCGCGGCGGCCGCGTTCGAAGCGCGCGACTGA

Upstream 100 bases:

>100_bases
TGGGCCACGTGAACTTCACGGCCGAAACGCGCGACGAAGCCGTTGCCGCGGCCACCGCGTGCGCGCAGCTGCTGCGCGTG
CCGCTCGACTGAGCCAGCCG

Downstream 100 bases:

>100_bases
CGCCAATCCCGGCACTGGAATGAAAAAACGCCCGACCGGCAAACCGGTCGGGCGTTTTCGTTTGGGCGCGTGGTCGGCGG
CTTACTTGCCGACGCCGGAC

Product: translation factor SUA5

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MSIDLPNSVTAAQIDAAAALLDAGQLVAFPTETVYGLGGDAANPEAVARIYAAKGRPANHPVIVHLPPGGDPGYWADDLP
ADAQALIDAFWPGPLTLILKRHARIPDAVSGGQDSVGLRCPSHPVAQALLAAFSARRGGHGGVAAPSANRFGHVSPTTAQ
HVRDEFGDTVHVLDGGASEVGIESTILDLSRGFPALLRPGHVTPQQIADVLGRAPRLPDGSDATAPRASGTLKAHYAPRT
PLALLPFDALEPLLAAAQTDGERVALVARASRAGRWAQADGVHFVAAPEDPQAYARDLYGMLRALDRAQVARILVEKLPE
TVEWIAVNDRLGRAAAAFEARD

Sequences:

>Translated_342_residues
MSIDLPNSVTAAQIDAAAALLDAGQLVAFPTETVYGLGGDAANPEAVARIYAAKGRPANHPVIVHLPPGGDPGYWADDLP
ADAQALIDAFWPGPLTLILKRHARIPDAVSGGQDSVGLRCPSHPVAQALLAAFSARRGGHGGVAAPSANRFGHVSPTTAQ
HVRDEFGDTVHVLDGGASEVGIESTILDLSRGFPALLRPGHVTPQQIADVLGRAPRLPDGSDATAPRASGTLKAHYAPRT
PLALLPFDALEPLLAAAQTDGERVALVARASRAGRWAQADGVHFVAAPEDPQAYARDLYGMLRALDRAQVARILVEKLPE
TVEWIAVNDRLGRAAAAFEARD
>Mature_341_residues
SIDLPNSVTAAQIDAAAALLDAGQLVAFPTETVYGLGGDAANPEAVARIYAAKGRPANHPVIVHLPPGGDPGYWADDLPA
DAQALIDAFWPGPLTLILKRHARIPDAVSGGQDSVGLRCPSHPVAQALLAAFSARRGGHGGVAAPSANRFGHVSPTTAQH
VRDEFGDTVHVLDGGASEVGIESTILDLSRGFPALLRPGHVTPQQIADVLGRAPRLPDGSDATAPRASGTLKAHYAPRTP
LALLPFDALEPLLAAAQTDGERVALVARASRAGRWAQADGVHFVAAPEDPQAYARDLYGMLRALDRAQVARILVEKLPET
VEWIAVNDRLGRAAAAFEARD

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Homo sapiens, GI58761510, Length=195, Percent_Identity=31.7948717948718, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI2367210, Length=178, Percent_Identity=30.3370786516854, Blast_Score=71, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6321269, Length=377, Percent_Identity=31.0344827586207, Blast_Score=147, Evalue=2e-36,
Organism=Drosophila melanogaster, GI78707274, Length=201, Percent_Identity=28.8557213930348, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 35730; Mature: 35598

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIDLPNSVTAAQIDAAAALLDAGQLVAFPTETVYGLGGDAANPEAVARIYAAKGRPANH
CCCCCCCCCHHHHHHHHHHHHCCCCEEEECCHHEEECCCCCCCHHHHHHHHHHCCCCCCC
PVIVHLPPGGDPGYWADDLPADAQALIDAFWPGPLTLILKRHARIPDAVSGGQDSVGLRC
CEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCC
PSHPVAQALLAAFSARRGGHGGVAAPSANRFGHVSPTTAQHVRDEFGDTVHVLDGGASEV
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCCCCC
GIESTILDLSRGFPALLRPGHVTPQQIADVLGRAPRLPDGSDATAPRASGTLKAHYAPRT
CHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCC
PLALLPFDALEPLLAAAQTDGERVALVARASRAGRWAQADGVHFVAAPEDPQAYARDLYG
CEEECCHHHHHHHHHHHCCCCCEEEEEEEHHHCCCCCCCCCEEEEECCCCHHHHHHHHHH
MLRALDRAQVARILVEKLPETVEWIAVNDRLGRAAAAFEARD
HHHHHHHHHHHHHHHHHCCHHEEEEEECCHHCHHHHHCCCCC
>Mature Secondary Structure 
SIDLPNSVTAAQIDAAAALLDAGQLVAFPTETVYGLGGDAANPEAVARIYAAKGRPANH
CCCCCCCCHHHHHHHHHHHHCCCCEEEECCHHEEECCCCCCCHHHHHHHHHHCCCCCCC
PVIVHLPPGGDPGYWADDLPADAQALIDAFWPGPLTLILKRHARIPDAVSGGQDSVGLRC
CEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCC
PSHPVAQALLAAFSARRGGHGGVAAPSANRFGHVSPTTAQHVRDEFGDTVHVLDGGASEV
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCCCCC
GIESTILDLSRGFPALLRPGHVTPQQIADVLGRAPRLPDGSDATAPRASGTLKAHYAPRT
CHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCC
PLALLPFDALEPLLAAAQTDGERVALVARASRAGRWAQADGVHFVAAPEDPQAYARDLYG
CEEECCHHHHHHHHHHHCCCCCEEEEEEEHHHCCCCCCCCCEEEEECCCCHHHHHHHHHH
MLRALDRAQVARILVEKLPETVEWIAVNDRLGRAAAAFEARD
HHHHHHHHHHHHHHHHHCCHHEEEEEECCHHCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]