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The map label for this gene is ssaB [H]

Identifier: 78067400

GI number: 78067400

Start: 3054918

End: 3055832

Strand: Direct

Name: ssaB [H]

Synonym: Bcep18194_A5931

Alternate gene names: 78067400

Gene position: 3054918-3055832 (Clockwise)

Preceding gene: 78067399

Following gene: 78067401

Centisome position: 82.7

GC content: 68.96

Gene sequence:

>915_bases
ATGTCCATTGCCCTGAAGCGCGCGCCGCGGCGTGCCCTGTCGCCTGTCCGCTGGCTCGCCGCCGCCGTCGCCGCGCTGTC
GCTCGCGGCGCCCGCATTCGCGCAGGCCGCGACCGTCAACGTCGTGGCCGCCGAGAATTTCTACGGCGATGTCGCGACGC
AAATCGGCGGCAGCCACGTCGCGGTCACGAGCATCCTCAGCAATCCGGACCAGGATCCGCACCTGTTCGAAGCGAGCCCG
AAAACGGCCCGCGCGCTCCAGCACGCGCAGGTCGTGATCTACAACGGCGCCAACTACGACCCGTGGATGAGCAAGCTGCT
CGGCGCGTCCAAGCAGGCGAAGCGCGCGACGATCGTCGTCGCCGATCTGGTCGGCAAGAAGGCCGGCGACAACCCGCACC
TGTGGTACGACCCGGCGACGATGCCGGCCGCCGCGCGCGCGATCGCGGCCGAGCTCGGCCGCGCCGACCCGGCGAACAAG
GCCGAATACGACGCGAACCTGCAGAAGTTCGTCGCGTCGCTGAAGCCCGTCGACGACAAGGTCGCCGCGCTGCGCGCGCA
GTACAAGGGCGTGCCGGTCACGGCCACCGAGCCCGTGTTCGGCTACATGTCCGACGCGATCGGCCTCGACATGCGCAACC
AGCGCTTCCAGCTCGCGACGATGAACGACACCGAGGCGAGCGCGCAGGACGTCGCCGCATTCGAGAACGACCTGCGCAAG
AAGCAGGTGCGCGTGCTGATCTACAACAGCCAGGCTGAAGAACCGATGACCAAGCGCATGCTGAAGATCGCGCGCGACGG
CGGCGTGCCGACCGTCAGCGTCACCGAGACGCAGCCGGCCGGCAAGACCTTCCAGCAATGGATGGCCGGCCAGCTCGACG
CGCTCTCGGCCGCGCTGGCAGCCGGCAAGCAATAA

Upstream 100 bases:

>100_bases
GTCGAGCTGAGCGGCCTGTGCGGGCACTGCAAGCACAAGCCGGTGCAACGCTGACGCGCATCGCGCGGCGCACGCGCCGC
CCCTTCCAACGAGGAGTTCC

Downstream 100 bases:

>100_bases
ACCACCGTAACGACATGACCGTCACTCCTCACGCACTCGCCGTCGATCGCGTCACGCTCGAACTGGGCGGACGCACGATC
CTGCGCGACGTCAGCTTCTC

Product: ABC heavy metal transporter, periplasmic ligand binding protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: Adhesin B; Saliva-binding protein [H]

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MSIALKRAPRRALSPVRWLAAAVAALSLAAPAFAQAATVNVVAAENFYGDVATQIGGSHVAVTSILSNPDQDPHLFEASP
KTARALQHAQVVIYNGANYDPWMSKLLGASKQAKRATIVVADLVGKKAGDNPHLWYDPATMPAAARAIAAELGRADPANK
AEYDANLQKFVASLKPVDDKVAALRAQYKGVPVTATEPVFGYMSDAIGLDMRNQRFQLATMNDTEASAQDVAAFENDLRK
KQVRVLIYNSQAEEPMTKRMLKIARDGGVPTVSVTETQPAGKTFQQWMAGQLDALSAALAAGKQ

Sequences:

>Translated_304_residues
MSIALKRAPRRALSPVRWLAAAVAALSLAAPAFAQAATVNVVAAENFYGDVATQIGGSHVAVTSILSNPDQDPHLFEASP
KTARALQHAQVVIYNGANYDPWMSKLLGASKQAKRATIVVADLVGKKAGDNPHLWYDPATMPAAARAIAAELGRADPANK
AEYDANLQKFVASLKPVDDKVAALRAQYKGVPVTATEPVFGYMSDAIGLDMRNQRFQLATMNDTEASAQDVAAFENDLRK
KQVRVLIYNSQAEEPMTKRMLKIARDGGVPTVSVTETQPAGKTFQQWMAGQLDALSAALAAGKQ
>Mature_303_residues
SIALKRAPRRALSPVRWLAAAVAALSLAAPAFAQAATVNVVAAENFYGDVATQIGGSHVAVTSILSNPDQDPHLFEASPK
TARALQHAQVVIYNGANYDPWMSKLLGASKQAKRATIVVADLVGKKAGDNPHLWYDPATMPAAARAIAAELGRADPANKA
EYDANLQKFVASLKPVDDKVAALRAQYKGVPVTATEPVFGYMSDAIGLDMRNQRFQLATMNDTEASAQDVAAFENDLRKK
QVRVLIYNSQAEEPMTKRMLKIARDGGVPTVSVTETQPAGKTFQQWMAGQLDALSAALAAGKQ

Specific function: Part of an ATP-driven transport system for manganese. Also act as an adhesin which is involved on adherence to extracellular matrix. It is an important factor in the pathogenesis and infection. It may contribute to the formation and accumulation of dental

COG id: COG0803

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Cell membrane; Lipid-anchor [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family. Lipoprotein receptor antigen (Lrai) subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006129
- InterPro:   IPR006128 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 32456; Mature: 32325

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIALKRAPRRALSPVRWLAAAVAALSLAAPAFAQAATVNVVAAENFYGDVATQIGGSHV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCHHHHHHHHCCCCHH
AVTSILSNPDQDPHLFEASPKTARALQHAQVVIYNGANYDPWMSKLLGASKQAKRATIVV
HHHHHHCCCCCCCCEECCCCHHHHHHHHCEEEEEECCCCCHHHHHHHCCCCCCCHHEEEE
ADLVGKKAGDNPHLWYDPATMPAAARAIAAELGRADPANKAEYDANLQKFVASLKPVDDK
EHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHH
VAALRAQYKGVPVTATEPVFGYMSDAIGLDMRNQRFQLATMNDTEASAQDVAAFENDLRK
HHHHHHHHCCCCCEECCCHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
KQVRVLIYNSQAEEPMTKRMLKIARDGGVPTVSVTETQPAGKTFQQWMAGQLDALSAALA
HEEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHCHHHHHHHHHH
AGKQ
CCCC
>Mature Secondary Structure 
SIALKRAPRRALSPVRWLAAAVAALSLAAPAFAQAATVNVVAAENFYGDVATQIGGSHV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCHHHHHHHHCCCCHH
AVTSILSNPDQDPHLFEASPKTARALQHAQVVIYNGANYDPWMSKLLGASKQAKRATIVV
HHHHHHCCCCCCCCEECCCCHHHHHHHHCEEEEEECCCCCHHHHHHHCCCCCCCHHEEEE
ADLVGKKAGDNPHLWYDPATMPAAARAIAAELGRADPANKAEYDANLQKFVASLKPVDDK
EHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHH
VAALRAQYKGVPVTATEPVFGYMSDAIGLDMRNQRFQLATMNDTEASAQDVAAFENDLRK
HHHHHHHHCCCCCEECCCHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
KQVRVLIYNSQAEEPMTKRMLKIARDGGVPTVSVTETQPAGKTFQQWMAGQLDALSAALA
HEEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHCHHHHHHHHHH
AGKQ
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1671775; 8419308 [H]