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The map label for this gene is murB

Identifier: 78067355

GI number: 78067355

Start: 3006714

End: 3007763

Strand: Reverse

Name: murB

Synonym: Bcep18194_A5886

Alternate gene names: 78067355

Gene position: 3007763-3006714 (Counterclockwise)

Preceding gene: 229260090

Following gene: 78067353

Centisome position: 81.42

GC content: 69.81

Gene sequence:

>1050_bases
ATGCCGATGCCTCTTGACGATTCCACCCTGTCGCTGCTTCCCGACCATCCGCTCGCCGCGCACAACACGTTCGGCATCGC
CGCGACCGCGCGCTTCGCCGCGCGCATCACGCATGCGTCGCAGTTCGAGGCGCTCCATCGCGACCCGCGCGTCGCGCACC
TGCCGCAGTTGGTGCTCGGCGGCGGCAGCAACGTCGTGTTCACGCGCGATTTCGACGGCGTCGTGCTGCTCGACGAGATC
GCGGGCCGCCGCGTCGTGCGCGAGGATGACGACGCGTGGTACGTCGAGGCTGGCGGCGGCGAGAACTGGCACGCATTCGT
CGCATGGACGCTCGAGCACGGGATGGCGGGCCTCGAGAACCTCGCGCTGATTCCGGGCACGGTCGGCGCGGCGCCGATCC
AGAACATCGGTGCGTACGGCCTCGAGATGAAGGCGTATTTTGACTCGCTGGTTGCGGTCGAGCTGGCGACGGGGTGCAGC
GAGCGCTTCGACGCCGCGCGCTGCGCGTTCGGCTATCGCGACAGCTTCTTCAAGCGGGAAGGGCGCGGCCGGTTTGCGAT
CGTGTCGGTGACGTTCCGGCTGCCGAAGCAATGGGTGCCGCGGCTCGGCTACGCGGATGTCACGCGCGAACTCGACGCCC
GAGGCATTGCACCCGATGCGGCCACGGCGCGCGACGTGTTCGACGCGGTCGTCGCGATCCGCCGCGCGAAGCTGCCCGAT
CCGCTCGTCCTCGGCAACGCGGGCAGTTTCTTCAAGAATCCGGTGATCGATGCGGCGCAGTTCGATGCGCTGCGCGCCCG
CGCACCGGAAGTCGTGTCATATCCGCAGCCGGACGGGCAGGTCAAGCTCGCGGCCGGCTGGCTGATCGACCGCTGCGGCT
GGAAGGGGCGCGCGCTGGGTGCGGCGGCCGTGCACGACCGCCAGGCGCTCGTGCTCGTCAATCGCGGCGGCGCGACGGGC
GCCGATGTGCTCGCGCTGGCACGGGCGATCCAGGCCGACGTGCAGACGCAATTCGGCGTCGAGCTCGAAGCCGAACCGGT
CTGCCTGTAA

Upstream 100 bases:

>100_bases
CGCGGGCACTCGCTATAATTGCGGACTGTTTGCCATTTTACCGATGCCCCTCCGTTTGCCCAAGGCCGGCCATGTGCCAC
CCGGGCGGACGTGACCGCGA

Downstream 100 bases:

>100_bases
CGCGGGCCCAGCGCAGCTTTTCCCGCGCTCAAACAAAAAGCGCCGATCGTCGATCGGCGCTTTTTTCATGGATGGCCCGG
TGCCGGCGCGTCAGTGCTTG

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MPMPLDDSTLSLLPDHPLAAHNTFGIAATARFAARITHASQFEALHRDPRVAHLPQLVLGGGSNVVFTRDFDGVVLLDEI
AGRRVVREDDDAWYVEAGGGENWHAFVAWTLEHGMAGLENLALIPGTVGAAPIQNIGAYGLEMKAYFDSLVAVELATGCS
ERFDAARCAFGYRDSFFKREGRGRFAIVSVTFRLPKQWVPRLGYADVTRELDARGIAPDAATARDVFDAVVAIRRAKLPD
PLVLGNAGSFFKNPVIDAAQFDALRARAPEVVSYPQPDGQVKLAAGWLIDRCGWKGRALGAAAVHDRQALVLVNRGGATG
ADVLALARAIQADVQTQFGVELEAEPVCL

Sequences:

>Translated_349_residues
MPMPLDDSTLSLLPDHPLAAHNTFGIAATARFAARITHASQFEALHRDPRVAHLPQLVLGGGSNVVFTRDFDGVVLLDEI
AGRRVVREDDDAWYVEAGGGENWHAFVAWTLEHGMAGLENLALIPGTVGAAPIQNIGAYGLEMKAYFDSLVAVELATGCS
ERFDAARCAFGYRDSFFKREGRGRFAIVSVTFRLPKQWVPRLGYADVTRELDARGIAPDAATARDVFDAVVAIRRAKLPD
PLVLGNAGSFFKNPVIDAAQFDALRARAPEVVSYPQPDGQVKLAAGWLIDRCGWKGRALGAAAVHDRQALVLVNRGGATG
ADVLALARAIQADVQTQFGVELEAEPVCL
>Mature_348_residues
PMPLDDSTLSLLPDHPLAAHNTFGIAATARFAARITHASQFEALHRDPRVAHLPQLVLGGGSNVVFTRDFDGVVLLDEIA
GRRVVREDDDAWYVEAGGGENWHAFVAWTLEHGMAGLENLALIPGTVGAAPIQNIGAYGLEMKAYFDSLVAVELATGCSE
RFDAARCAFGYRDSFFKREGRGRFAIVSVTFRLPKQWVPRLGYADVTRELDARGIAPDAATARDVFDAVVAIRRAKLPDP
LVLGNAGSFFKNPVIDAAQFDALRARAPEVVSYPQPDGQVKLAAGWLIDRCGWKGRALGAAAVHDRQALVLVNRGGATGA
DVLALARAIQADVQTQFGVELEAEPVCL

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=334, Percent_Identity=50, Blast_Score=312, Evalue=2e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 37566; Mature: 37435

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMPLDDSTLSLLPDHPLAAHNTFGIAATARFAARITHASQFEALHRDPRVAHLPQLVLG
CCCCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCEEEC
GGSNVVFTRDFDGVVLLDEIAGRRVVREDDDAWYVEAGGGENWHAFVAWTLEHGMAGLEN
CCCCEEEEECCCCEEEEEHHCCCEEEECCCCEEEEECCCCCCEEEEEEEEEHHCCCCCCC
LALIPGTVGAAPIQNIGAYGLEMKAYFDSLVAVELATGCSERFDAARCAFGYRDSFFKRE
CEECCCCCCCCCHHHCCCCCEEHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHC
GRGRFAIVSVTFRLPKQWVPRLGYADVTRELDARGIAPDAATARDVFDAVVAIRRAKLPD
CCCCEEEEEEEEECCHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCC
PLVLGNAGSFFKNPVIDAAQFDALRARAPEVVSYPQPDGQVKLAAGWLIDRCGWKGRALG
CEEECCCCCHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEECEEHHCCCCCCCCCC
AAAVHDRQALVLVNRGGATGADVLALARAIQADVQTQFGVELEAEPVCL
HHEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEECCCCCCC
>Mature Secondary Structure 
PMPLDDSTLSLLPDHPLAAHNTFGIAATARFAARITHASQFEALHRDPRVAHLPQLVLG
CCCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCEEEC
GGSNVVFTRDFDGVVLLDEIAGRRVVREDDDAWYVEAGGGENWHAFVAWTLEHGMAGLEN
CCCCEEEEECCCCEEEEEHHCCCEEEECCCCEEEEECCCCCCEEEEEEEEEHHCCCCCCC
LALIPGTVGAAPIQNIGAYGLEMKAYFDSLVAVELATGCSERFDAARCAFGYRDSFFKRE
CEECCCCCCCCCHHHCCCCCEEHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHC
GRGRFAIVSVTFRLPKQWVPRLGYADVTRELDARGIAPDAATARDVFDAVVAIRRAKLPD
CCCCEEEEEEEEECCHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCC
PLVLGNAGSFFKNPVIDAAQFDALRARAPEVVSYPQPDGQVKLAAGWLIDRCGWKGRALG
CEEECCCCCHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEECEEHHCCCCCCCCCC
AAAVHDRQALVLVNRGGATGADVLALARAIQADVQTQFGVELEAEPVCL
HHEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA