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The map label for this gene is argF [H]

Identifier: 78067354

GI number: 78067354

Start: 3005694

End: 3006623

Strand: Direct

Name: argF [H]

Synonym: Bcep18194_A5885

Alternate gene names: 78067354

Gene position: 3005694-3006623 (Clockwise)

Preceding gene: 78067352

Following gene: 78067356

Centisome position: 81.36

GC content: 63.55

Gene sequence:

>930_bases
ATGACCGCCAAAACCATTCGTCACTACCTGCAGTTCACGGATTTCTCGCTGGAAGACTACGAGTACGTGCTCGAACGCAC
GGGTATCCTGAAGCGCAAGTTCAAGAACTACGAGACCTATCACCCGCTGCATGACCGCACGCTCGCGATGATCTTCGAGA
AGAGCTCGACGCGCACGCGCCTGTCGTTCGAAGCCGGGATCTTCCAGCTCGGCGGCCACGCCGTCTTCATGAGCACGCGC
GACACGCAGCTCGGCCGCGGCGAACCCGTCGAGGATTCCGCGCAGGTCATCTCGCGAATGGTCGACATCATCATGATCCG
TACGTTCGAGCAGGAGGTCATCAAGCGCTTCGCGGACAATTCCCGCGTGCCGGTGATCAACGGCCTGACGAACGAGTACC
ACCCGTGCCAGGTGCTCGCCGACATCTTCACGTACTACGAGCACCGCGGCCCGATCGCCGGCAAGACCGTCGCATGGGTC
GGCGATGCGAACAACATGCTCTACACGTGGATCGAGGCGGCGCAGATCCTCGGCTTCAAGCTGCGCCTGTCCACGCCGCC
CGGCTACGCGCTCGACATGAAGCTCGTGTCGCCCGACAGCGCACCGTTCTACGAAGTGTTCGAGGATCCGAACGAAGCGT
GCAAGGGCGCCGACCTCGTCACCACCGACGTGTGGACGAGCATGGGCTTCGAGGCCGAGAACGAGGCCCGCATGCAGGCA
TTCGCCGACTGGTGCGTCGACGAGGAAATGATGGGCCACGCGAACCCGGACGCCCTCTTCATGCACTGCCTGCCCGCGCA
CCGCGGCGAGGAAGTGACGGCCGGCGTGATCGACGGCCCGCAGAGCGTCGTGTGGGACGAAGCGGAAAACCGCCTGCACG
TGCAGAAGGCCCTGATGGAGTTCCTGCTGCTCGGCCGCCTCAAGCACTGA

Upstream 100 bases:

>100_bases
TCAAAGCACAGAAAATCCTTTATGCTGCTTTGAGTTATCCACACCCGACGGCGGCGCCGTCCGGCCCTGCTGCCGGGTGC
AACCTGCCGCATCTCGCTTC

Downstream 100 bases:

>100_bases
CGCGCCGGCACCGGGCCATCCATGAAAAAAGCGCCGATCGACGATCGGCGCTTTTTGTTTGAGCGCGGGAAAAGCTGCGC
TGGGCCCGCGTTACAGGCAG

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MTAKTIRHYLQFTDFSLEDYEYVLERTGILKRKFKNYETYHPLHDRTLAMIFEKSSTRTRLSFEAGIFQLGGHAVFMSTR
DTQLGRGEPVEDSAQVISRMVDIIMIRTFEQEVIKRFADNSRVPVINGLTNEYHPCQVLADIFTYYEHRGPIAGKTVAWV
GDANNMLYTWIEAAQILGFKLRLSTPPGYALDMKLVSPDSAPFYEVFEDPNEACKGADLVTTDVWTSMGFEAENEARMQA
FADWCVDEEMMGHANPDALFMHCLPAHRGEEVTAGVIDGPQSVVWDEAENRLHVQKALMEFLLLGRLKH

Sequences:

>Translated_309_residues
MTAKTIRHYLQFTDFSLEDYEYVLERTGILKRKFKNYETYHPLHDRTLAMIFEKSSTRTRLSFEAGIFQLGGHAVFMSTR
DTQLGRGEPVEDSAQVISRMVDIIMIRTFEQEVIKRFADNSRVPVINGLTNEYHPCQVLADIFTYYEHRGPIAGKTVAWV
GDANNMLYTWIEAAQILGFKLRLSTPPGYALDMKLVSPDSAPFYEVFEDPNEACKGADLVTTDVWTSMGFEAENEARMQA
FADWCVDEEMMGHANPDALFMHCLPAHRGEEVTAGVIDGPQSVVWDEAENRLHVQKALMEFLLLGRLKH
>Mature_308_residues
TAKTIRHYLQFTDFSLEDYEYVLERTGILKRKFKNYETYHPLHDRTLAMIFEKSSTRTRLSFEAGIFQLGGHAVFMSTRD
TQLGRGEPVEDSAQVISRMVDIIMIRTFEQEVIKRFADNSRVPVINGLTNEYHPCQVLADIFTYYEHRGPIAGKTVAWVG
DANNMLYTWIEAAQILGFKLRLSTPPGYALDMKLVSPDSAPFYEVFEDPNEACKGADLVTTDVWTSMGFEAENEARMQAF
ADWCVDEEMMGHANPDALFMHCLPAHRGEEVTAGVIDGPQSVVWDEAENRLHVQKALMEFLLLGRLKH

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=304, Percent_Identity=38.8157894736842, Blast_Score=216, Evalue=2e-56,
Organism=Homo sapiens, GI18105007, Length=308, Percent_Identity=26.6233766233766, Blast_Score=98, Evalue=9e-21,
Organism=Escherichia coli, GI1786469, Length=325, Percent_Identity=37.8461538461538, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1790703, Length=325, Percent_Identity=36.3076923076923, Blast_Score=195, Evalue=3e-51,
Organism=Escherichia coli, GI2367364, Length=310, Percent_Identity=27.741935483871, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI48994908, Length=307, Percent_Identity=25.7328990228013, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193204318, Length=296, Percent_Identity=26.6891891891892, Blast_Score=81, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6322373, Length=323, Percent_Identity=33.1269349845201, Blast_Score=194, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6322331, Length=315, Percent_Identity=24.1269841269841, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24642586, Length=321, Percent_Identity=26.4797507788162, Blast_Score=98, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 35259; Mature: 35127

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAKTIRHYLQFTDFSLEDYEYVLERTGILKRKFKNYETYHPLHDRTLAMIFEKSSTRTR
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCEE
LSFEAGIFQLGGHAVFMSTRDTQLGRGEPVEDSAQVISRMVDIIMIRTFEQEVIKRFADN
EEECCCCEEECCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SRVPVINGLTNEYHPCQVLADIFTYYEHRGPIAGKTVAWVGDANNMLYTWIEAAQILGFK
CCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHEEE
LRLSTPPGYALDMKLVSPDSAPFYEVFEDPNEACKGADLVTTDVWTSMGFEAENEARMQA
EEECCCCCCEEEEEEECCCCCCHHHHHCCHHHHHCCCCEEEHHHHHHCCCCCCHHHHHHH
FADWCVDEEMMGHANPDALFMHCLPAHRGEEVTAGVIDGPQSVVWDEAENRLHVQKALME
HHHHHCCHHHHCCCCCCCEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
FLLLGRLKH
HHHHHHCCC
>Mature Secondary Structure 
TAKTIRHYLQFTDFSLEDYEYVLERTGILKRKFKNYETYHPLHDRTLAMIFEKSSTRTR
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCEE
LSFEAGIFQLGGHAVFMSTRDTQLGRGEPVEDSAQVISRMVDIIMIRTFEQEVIKRFADN
EEECCCCEEECCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SRVPVINGLTNEYHPCQVLADIFTYYEHRGPIAGKTVAWVGDANNMLYTWIEAAQILGFK
CCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHEEE
LRLSTPPGYALDMKLVSPDSAPFYEVFEDPNEACKGADLVTTDVWTSMGFEAENEARMQA
EEECCCCCCEEEEEEECCCCCCHHHHHCCHHHHHCCCCEEEHHHHHHCCCCCCHHHHHHH
FADWCVDEEMMGHANPDALFMHCLPAHRGEEVTAGVIDGPQSVVWDEAENRLHVQKALME
HHHHHCCHHHHCCCCCCCEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
FLLLGRLKH
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA