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The map label for this gene is lpxK [H]

Identifier: 78067345

GI number: 78067345

Start: 2997689

End: 2998717

Strand: Direct

Name: lpxK [H]

Synonym: Bcep18194_A5876

Alternate gene names: 78067345

Gene position: 2997689-2998717 (Clockwise)

Preceding gene: 78067342

Following gene: 78067346

Centisome position: 81.15

GC content: 73.18

Gene sequence:

>1029_bases
ATGAGCGCGCCCGACGGCCCGCTCGCCCGGCTCGAAGCCCGCCTGACGCGCGAATGGCAGCGCCGCGGCGCGCTCGCGTG
GGCGCTCACGCCGTTCGCGTGCGTGTTCGGCCTGTGCGCGGCACTGCGGCGCACCGCGTACGCGCAGGGCTGGAAGAAAC
CGGTCGACGTCGGCGTGCCCGTCGTCGTGGTCGGCAACGTGACCGTCGGCGGCACCGGCAAGACGCCGACCGTAATCGCC
CTCGTCGACGCGTTGCGAGCGGCCGGCTTCACGCCCGGCATCGTGTCGCGCGGCTACGGCGCGAACGTGAAGGCGCCGAC
CGCCGTCACGACCGCGTCGCGCGCCAGCGCGGGCGGCGACGAACCGCTCCTGATCGCACGCCGCACCGGCGCGCCGGTCT
GGGTCTGCCCCGATCGCGTCGCGGCCGCGCAGGCGCTGCGCGCCGCGCATCCGGACGTCGACGTGATCGTCAGCGACGAC
GGCCTACAGCACTACCGCCTCGCGCGCACGGTCGAGCTCGTCGTGTTCGACCACCGGCTCGGCGGCAACGGCTTCCTGCT
GCCGGCCGGGCCGTTGCGCGAGCCGCTGTCGCGGCACCGTGACGCCACGCTCGTCAACGATCCGTACAGCGGCGCGCTGC
CGCCGTGGCCCGACACCTATTCGCTCGCGCTCACGCCGGGCGCCGCGTGGCACCTCGACCAGCCCGCGCTGCGACGCCCG
CTGTCGCAATTCGCGAACGAGCGCGTGCTCGCCGCGGCCGGCATCGGCGCGCCGGAACGCTTTTTCGCGACGCTGCGCTC
GGCCGGTCTCGCGCCCGCGACGCGCGCGCTGCCCGACCACTACGCGTTCGCCGACAATCCGTTCGTCGACGACGCCGTCG
ATGCGATCCTGATCACCGAGAAGGATGCAGTAAAATTGGGCGCTTCCTGGCGCGACGCCCGACTGTGGGTTGTCCCCGTC
GAAGCCGCGCTCGACCCTCGCCTCATTGCCCTCGTTGTGGAGAAACTCCGTGGACGCTCGCCTGCTTGA

Upstream 100 bases:

>100_bases
GCCGCCTTCCGAAGACCCTGCGGCATGTGCCGCCCAACGGAGAATCCGCCTTGACGAATCCGTCCCACGCCGCGGCGCAC
GAGATGCCGCGCCCGGCCCG

Downstream 100 bases:

>100_bases
AATCCTTGTGTGCCCTATCTGCAAAGGCCCGCTCCACTATGACCGTGCCGCGCAGGAGCTGATCTGCAACGCGGACAAGC
TCGCCTACCCGATCCGCGAC

Product: tetraacyldisaccharide 4'-kinase

Products: NA

Alternate protein names: Lipid A 4'-kinase [H]

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MSAPDGPLARLEARLTREWQRRGALAWALTPFACVFGLCAALRRTAYAQGWKKPVDVGVPVVVVGNVTVGGTGKTPTVIA
LVDALRAAGFTPGIVSRGYGANVKAPTAVTTASRASAGGDEPLLIARRTGAPVWVCPDRVAAAQALRAAHPDVDVIVSDD
GLQHYRLARTVELVVFDHRLGGNGFLLPAGPLREPLSRHRDATLVNDPYSGALPPWPDTYSLALTPGAAWHLDQPALRRP
LSQFANERVLAAAGIGAPERFFATLRSAGLAPATRALPDHYAFADNPFVDDAVDAILITEKDAVKLGASWRDARLWVVPV
EAALDPRLIALVVEKLRGRSPA

Sequences:

>Translated_342_residues
MSAPDGPLARLEARLTREWQRRGALAWALTPFACVFGLCAALRRTAYAQGWKKPVDVGVPVVVVGNVTVGGTGKTPTVIA
LVDALRAAGFTPGIVSRGYGANVKAPTAVTTASRASAGGDEPLLIARRTGAPVWVCPDRVAAAQALRAAHPDVDVIVSDD
GLQHYRLARTVELVVFDHRLGGNGFLLPAGPLREPLSRHRDATLVNDPYSGALPPWPDTYSLALTPGAAWHLDQPALRRP
LSQFANERVLAAAGIGAPERFFATLRSAGLAPATRALPDHYAFADNPFVDDAVDAILITEKDAVKLGASWRDARLWVVPV
EAALDPRLIALVVEKLRGRSPA
>Mature_341_residues
SAPDGPLARLEARLTREWQRRGALAWALTPFACVFGLCAALRRTAYAQGWKKPVDVGVPVVVVGNVTVGGTGKTPTVIAL
VDALRAAGFTPGIVSRGYGANVKAPTAVTTASRASAGGDEPLLIARRTGAPVWVCPDRVAAAQALRAAHPDVDVIVSDDG
LQHYRLARTVELVVFDHRLGGNGFLLPAGPLREPLSRHRDATLVNDPYSGALPPWPDTYSLALTPGAAWHLDQPALRRPL
SQFANERVLAAAGIGAPERFFATLRSAGLAPATRALPDHYAFADNPFVDDAVDAILITEKDAVKLGASWRDARLWVVPVE
AALDPRLIALVVEKLRGRSPA

Specific function: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) [H]

COG id: COG1663

COG function: function code M; Tetraacyldisaccharide-1-P 4'-kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxK family [H]

Homologues:

Organism=Escherichia coli, GI1787144, Length=319, Percent_Identity=43.2601880877743, Blast_Score=205, Evalue=3e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003758 [H]

Pfam domain/function: PF02606 LpxK [H]

EC number: =2.7.1.130 [H]

Molecular weight: Translated: 36316; Mature: 36185

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPDGPLARLEARLTREWQRRGALAWALTPFACVFGLCAALRRTAYAQGWKKPVDVGVP
CCCCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
VVVVGNVTVGGTGKTPTVIALVDALRAAGFTPGIVSRGYGANVKAPTAVTTASRASAGGD
EEEEECEEECCCCCCCHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCEEEECCCCCCCCC
EPLLIARRTGAPVWVCPDRVAAAQALRAAHPDVDVIVSDDGLQHYRLARTVELVVFDHRL
CCEEEEECCCCCEEECCHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHEEEEEEEEEEE
GGNGFLLPAGPLREPLSRHRDATLVNDPYSGALPPWPDTYSLALTPGAAWHLDQPALRRP
CCCEEEECCCHHHHHHHHCCCCEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHH
LSQFANERVLAAAGIGAPERFFATLRSAGLAPATRALPDHYAFADNPFVDDAVDAILITE
HHHHHCCCEEEEECCCCHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCHHHCCEEEEEC
KDAVKLGASWRDARLWVVPVEAALDPRLIALVVEKLRGRSPA
CCHHEECCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SAPDGPLARLEARLTREWQRRGALAWALTPFACVFGLCAALRRTAYAQGWKKPVDVGVP
CCCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
VVVVGNVTVGGTGKTPTVIALVDALRAAGFTPGIVSRGYGANVKAPTAVTTASRASAGGD
EEEEECEEECCCCCCCHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCEEEECCCCCCCCC
EPLLIARRTGAPVWVCPDRVAAAQALRAAHPDVDVIVSDDGLQHYRLARTVELVVFDHRL
CCEEEEECCCCCEEECCHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHEEEEEEEEEEE
GGNGFLLPAGPLREPLSRHRDATLVNDPYSGALPPWPDTYSLALTPGAAWHLDQPALRRP
CCCEEEECCCHHHHHHHHCCCCEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHH
LSQFANERVLAAAGIGAPERFFATLRSAGLAPATRALPDHYAFADNPFVDDAVDAILITE
HHHHHCCCEEEEECCCCHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCHHHCCEEEEEC
KDAVKLGASWRDARLWVVPVEAALDPRLIALVVEKLRGRSPA
CCHHEECCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA