Click here to switch to the map view.

The map label for this gene is argD

Identifier: 78067292

GI number: 78067292

Start: 2937971

End: 2939155

Strand: Direct

Name: argD

Synonym: Bcep18194_A5823

Alternate gene names: 78067292

Gene position: 2937971-2939155 (Clockwise)

Preceding gene: 78067291

Following gene: 78067293

Centisome position: 79.53

GC content: 64.64

Gene sequence:

>1185_bases
ATGCCCCTGAACGATTACCCGATCGACTCGCTGATGTACATCACGAACCGCCCCGACATCGTGTTTACGCACGGCAAGGG
TTCGTGGCTCTACGATCACACGGGCAAGCGCTATCTGGACTTCATCCAGGGCTGGGCCGTCAACAGCCTCGGCCATTGCA
ACGAAGGCATCGTCGAAGCGCTGAAGACGCAGGCGGAAAAGCTGCTGAACCCGTCGCCCGCGTTCTACAACGAACCGATG
GCGAAGCTTGCCGGCCTGCTCACGCAGCACAGCGTGTTCGACAAGGTGTTCTTCACGAACAGCGGCGCGGAAGCGAACGA
AGGCGCGATCAAGCTCGCGCGCAAGTGGGGCCGCAAGTTCAAGAACGGCGCGTACGAGATCATCACGTTCGACCACAGCT
TCCACGGCCGCACGCTCGCGACGATGTCGGCCAGCGGCAAGCCGGGCTGGGACACGATCTACGCGCCGCAGGTGCCGGGC
TTCCCGAAGGCCGAGCTGAACGACATCAACTCCGTCGAGAAGCTGATCACCGACAAGACCGTCGCGGTGATGCTCGAGCC
GATCCAGGGTGAAGGCGGCGTGATTCCGGCCACGCGTGAATTCATGCAGGCGCTGCGCGCGCTGACGAAGCAGCACAACC
TGCTGCTGATCGTCGACGAAGTGCAAAGCGGCTGCGGCCGTGCGGGCACGCTGTTCGCGTACGAGCTGTCCGGCATCGAG
CCGGACGTCATGACGCTCGCGAAAGGCATCGGCGGCGGCGCCCCGCTCGGCGCGCTGCTGTCGAAGGCCGAGTTCGCGGT
GTTCGAGGCCGGCGACCAGGGCGGCACGTACAACGGCAACCCGCTGATGACCGCGGTCGGCTATTCGGTGATCTCGCAGC
TTGTCGCGCCGGGCTTCCTCGAAGGCGTGCGTGCGCGCAGCGAATACCTGAAGCGCAAGCTGCTCGAGCTGTCGGAAGAG
CGCGGCTTCGAAGGCGAACGCGGCGAAGGCCTGCTGCGCGCGCTGCTGCTGGGCAAGGACATCGGCCCGCAGATCGTCGA
GAAGGCGCGCGACATGCAACCCGATGGCCTGCTGCTGAACGCCGCGCGGCCGAACCTGCTGCGCTTCATGCCCGCACTGA
ACGTGACGACCGAAGAAATCGACCAGATGATGGCGATGCTGCGGTCGATTCTCGACACGCTCTAA

Upstream 100 bases:

>100_bases
CTTCACCGGTTACGCACAAGCTGTTCGACCCACCAGCCACGGCCTTCCGTGGCTTTTTTATTGCCTGTTTCCCTTTCAAC
GTCCGCTGGAGTCTGCTGCC

Downstream 100 bases:

>100_bases
GGAGACCGCCGCGATGGATGCCGCCGCCGATGCTGTTGCAATCCGCCCGTTCGAACGCGCCGACACCGATGCCGTGCTCA
CGGTATGGCGCGACGCGTTC

Product: acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MPLNDYPIDSLMYITNRPDIVFTHGKGSWLYDHTGKRYLDFIQGWAVNSLGHCNEGIVEALKTQAEKLLNPSPAFYNEPM
AKLAGLLTQHSVFDKVFFTNSGAEANEGAIKLARKWGRKFKNGAYEIITFDHSFHGRTLATMSASGKPGWDTIYAPQVPG
FPKAELNDINSVEKLITDKTVAVMLEPIQGEGGVIPATREFMQALRALTKQHNLLLIVDEVQSGCGRAGTLFAYELSGIE
PDVMTLAKGIGGGAPLGALLSKAEFAVFEAGDQGGTYNGNPLMTAVGYSVISQLVAPGFLEGVRARSEYLKRKLLELSEE
RGFEGERGEGLLRALLLGKDIGPQIVEKARDMQPDGLLLNAARPNLLRFMPALNVTTEEIDQMMAMLRSILDTL

Sequences:

>Translated_394_residues
MPLNDYPIDSLMYITNRPDIVFTHGKGSWLYDHTGKRYLDFIQGWAVNSLGHCNEGIVEALKTQAEKLLNPSPAFYNEPM
AKLAGLLTQHSVFDKVFFTNSGAEANEGAIKLARKWGRKFKNGAYEIITFDHSFHGRTLATMSASGKPGWDTIYAPQVPG
FPKAELNDINSVEKLITDKTVAVMLEPIQGEGGVIPATREFMQALRALTKQHNLLLIVDEVQSGCGRAGTLFAYELSGIE
PDVMTLAKGIGGGAPLGALLSKAEFAVFEAGDQGGTYNGNPLMTAVGYSVISQLVAPGFLEGVRARSEYLKRKLLELSEE
RGFEGERGEGLLRALLLGKDIGPQIVEKARDMQPDGLLLNAARPNLLRFMPALNVTTEEIDQMMAMLRSILDTL
>Mature_393_residues
PLNDYPIDSLMYITNRPDIVFTHGKGSWLYDHTGKRYLDFIQGWAVNSLGHCNEGIVEALKTQAEKLLNPSPAFYNEPMA
KLAGLLTQHSVFDKVFFTNSGAEANEGAIKLARKWGRKFKNGAYEIITFDHSFHGRTLATMSASGKPGWDTIYAPQVPGF
PKAELNDINSVEKLITDKTVAVMLEPIQGEGGVIPATREFMQALRALTKQHNLLLIVDEVQSGCGRAGTLFAYELSGIEP
DVMTLAKGIGGGAPLGALLSKAEFAVFEAGDQGGTYNGNPLMTAVGYSVISQLVAPGFLEGVRARSEYLKRKLLELSEER
GFEGERGEGLLRALLLGKDIGPQIVEKARDMQPDGLLLNAARPNLLRFMPALNVTTEEIDQMMAMLRSILDTL

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=378, Percent_Identity=31.4814814814815, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI284507298, Length=298, Percent_Identity=30.5369127516779, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI13994255, Length=427, Percent_Identity=27.4004683840749, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI37574042, Length=416, Percent_Identity=28.8461538461538, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI24119277, Length=417, Percent_Identity=26.8585131894484, Blast_Score=121, Evalue=9e-28,
Organism=Homo sapiens, GI226442705, Length=416, Percent_Identity=28.125, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI226442709, Length=386, Percent_Identity=29.0155440414508, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI188536080, Length=427, Percent_Identity=23.4192037470726, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI38679950, Length=427, Percent_Identity=23.4192037470726, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI38679946, Length=427, Percent_Identity=23.4192037470726, Blast_Score=84, Evalue=3e-16,
Organism=Escherichia coli, GI1788044, Length=359, Percent_Identity=45.125348189415, Blast_Score=299, Evalue=2e-82,
Organism=Escherichia coli, GI1789759, Length=371, Percent_Identity=42.3180592991914, Blast_Score=278, Evalue=6e-76,
Organism=Escherichia coli, GI1789016, Length=398, Percent_Identity=32.4120603015075, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI145693181, Length=391, Percent_Identity=30.4347826086957, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1787560, Length=398, Percent_Identity=30.9045226130653, Blast_Score=141, Evalue=9e-35,
Organism=Escherichia coli, GI1786349, Length=312, Percent_Identity=33.0128205128205, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1786991, Length=315, Percent_Identity=28.2539682539683, Blast_Score=93, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI25144271, Length=380, Percent_Identity=32.1052631578947, Blast_Score=211, Evalue=4e-55,
Organism=Caenorhabditis elegans, GI32564660, Length=417, Percent_Identity=28.7769784172662, Blast_Score=154, Evalue=9e-38,
Organism=Caenorhabditis elegans, GI25144274, Length=277, Percent_Identity=31.7689530685921, Blast_Score=144, Evalue=9e-35,
Organism=Caenorhabditis elegans, GI71992977, Length=416, Percent_Identity=27.8846153846154, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI71981843, Length=159, Percent_Identity=31.4465408805031, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17541228, Length=349, Percent_Identity=25.5014326647564, Blast_Score=82, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6324432, Length=401, Percent_Identity=33.6658354114713, Blast_Score=209, Evalue=5e-55,
Organism=Saccharomyces cerevisiae, GI6323470, Length=397, Percent_Identity=31.2342569269521, Blast_Score=181, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6321456, Length=425, Percent_Identity=25.1764705882353, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6324386, Length=462, Percent_Identity=25.1082251082251, Blast_Score=80, Evalue=8e-16,
Organism=Drosophila melanogaster, GI21357415, Length=378, Percent_Identity=32.5396825396825, Blast_Score=208, Evalue=4e-54,
Organism=Drosophila melanogaster, GI161085790, Length=415, Percent_Identity=27.2289156626506, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI21356575, Length=427, Percent_Identity=26.9320843091335, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI28574759, Length=410, Percent_Identity=27.5609756097561, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI281366494, Length=293, Percent_Identity=25.5972696245734, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24667139, Length=293, Percent_Identity=25.5972696245734, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24667143, Length=293, Percent_Identity=25.5972696245734, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43049; Mature: 42918

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS00599 AA_TRANSFER_CLASS_2 ; PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLNDYPIDSLMYITNRPDIVFTHGKGSWLYDHTGKRYLDFIQGWAVNSLGHCNEGIVEA
CCCCCCCCCCEEEEECCCCEEEECCCCCEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHH
LKTQAEKLLNPSPAFYNEPMAKLAGLLTQHSVFDKVFFTNSGAEANEGAIKLARKWGRKF
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHH
KNGAYEIITFDHSFHGRTLATMSASGKPGWDTIYAPQVPGFPKAELNDINSVEKLITDKT
CCCCEEEEEECCCCCCCEEEEEECCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHCCE
VAVMLEPIQGEGGVIPATREFMQALRALTKQHNLLLIVDEVQSGCGRAGTLFAYELSGIE
EEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCCCEEEEEEECCCC
PDVMTLAKGIGGGAPLGALLSKAEFAVFEAGDQGGTYNGNPLMTAVGYSVISQLVAPGFL
HHHHHHHHHCCCCCCHHHHHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCHHH
EGVRARSEYLKRKLLELSEERGFEGERGEGLLRALLLGKDIGPQIVEKARDMQPDGLLLN
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEE
AARPNLLRFMPALNVTTEEIDQMMAMLRSILDTL
CCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
PLNDYPIDSLMYITNRPDIVFTHGKGSWLYDHTGKRYLDFIQGWAVNSLGHCNEGIVEA
CCCCCCCCCEEEEECCCCEEEECCCCCEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHH
LKTQAEKLLNPSPAFYNEPMAKLAGLLTQHSVFDKVFFTNSGAEANEGAIKLARKWGRKF
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHH
KNGAYEIITFDHSFHGRTLATMSASGKPGWDTIYAPQVPGFPKAELNDINSVEKLITDKT
CCCCEEEEEECCCCCCCEEEEEECCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHCCE
VAVMLEPIQGEGGVIPATREFMQALRALTKQHNLLLIVDEVQSGCGRAGTLFAYELSGIE
EEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCCCEEEEEEECCCC
PDVMTLAKGIGGGAPLGALLSKAEFAVFEAGDQGGTYNGNPLMTAVGYSVISQLVAPGFL
HHHHHHHHHCCCCCCHHHHHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCHHH
EGVRARSEYLKRKLLELSEERGFEGERGEGLLRALLLGKDIGPQIVEKARDMQPDGLLLN
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEE
AARPNLLRFMPALNVTTEEIDQMMAMLRSILDTL
CCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]