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The map label for this gene is cysH1 [H]

Identifier: 78067273

GI number: 78067273

Start: 2918039

End: 2918791

Strand: Reverse

Name: cysH1 [H]

Synonym: Bcep18194_A5804

Alternate gene names: 78067273

Gene position: 2918791-2918039 (Counterclockwise)

Preceding gene: 78067274

Following gene: 78067272

Centisome position: 79.01

GC content: 67.2

Gene sequence:

>753_bases
ATGAGCACCGCGACCGCCACTGCGCTGACGCCGGAGCTCGCCGCGAAGGTCGAGCGCCTCGACGCGCTGCTCGCGCAGAT
CGGCGCCCGTCACGAGAAGGTGAAGTTCGCGAGCAGCCTTGCGGCGGAAGACATGCTGCTGACGCATGCAATCCTGTCGA
AGGGCGCGCGAATCGGCATCTTCTCGCTGAACACCGGCCGCCTGCACGCGGAAACGCTCGGCATGATCGACCGTGTGTGC
GAGCGTTACGGCTACGAGATCGAGCAGTTCCATCCGCTGCAGGACGCGGTCGACCAGTACGTCGCCGAGCACGGCCTGAA
CGCGTTCTACGAGAGCGTCGAGCTGCGCAAGTCGTGCTGTCACATCCGCAAGGTCGAGCCGCTGAATCGCGCGCTCGCGG
ACGTCGGCGCATGGGTCACGGGCCAGCGCCGCGAGCAGTCGGTCACGCGTGCCGAGTTGCACGAGGAAGAACAGGACGAA
GCGCGCGGGATCGCGAAGTACAATCCGCTCGCCGACTGGACGGAAAGCGACGTGTGGGCGTACCTTAATGCGTTTGACGT
GCCGGTGAACCCGCTGCATGCGCGCGGCTACCCGAGCATCGGCTGCGAGCCGTGTACGCGGGCGATCCGTCCCGGCGAGG
ACAGCCGCGCGGGCCGCTGGTGGTGGGAGTCGCGCGATACGAAGGAATGCGGGCTGCACATCACGACGATCACGCCGATT
CCCGCGGATGCCGTTGCCGGCGCCACGCACTGA

Upstream 100 bases:

>100_bases
ATGCGTTCACGGAATTCACGCAGCGTTACCAGGGCGCGTTCGACCAGCCCGAACCGCTGTTCCGTCGCCGCGCCGCGGCG
CCCGACGCCAAGGTGAACGC

Downstream 100 bases:

>100_bases
AAGCCTGACAAGAAACTGAATATTGCGCCGCCTGCGACAGCGGGCGGCACGAACCCAGAAGAGAAGGACTGAAATCATGA
GCACGACGCTCGAGCAATCC

Product: phosphoadenosine phosphosulfate reductase

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MSTATATALTPELAAKVERLDALLAQIGARHEKVKFASSLAAEDMLLTHAILSKGARIGIFSLNTGRLHAETLGMIDRVC
ERYGYEIEQFHPLQDAVDQYVAEHGLNAFYESVELRKSCCHIRKVEPLNRALADVGAWVTGQRREQSVTRAELHEEEQDE
ARGIAKYNPLADWTESDVWAYLNAFDVPVNPLHARGYPSIGCEPCTRAIRPGEDSRAGRWWWESRDTKECGLHITTITPI
PADAVAGATH

Sequences:

>Translated_250_residues
MSTATATALTPELAAKVERLDALLAQIGARHEKVKFASSLAAEDMLLTHAILSKGARIGIFSLNTGRLHAETLGMIDRVC
ERYGYEIEQFHPLQDAVDQYVAEHGLNAFYESVELRKSCCHIRKVEPLNRALADVGAWVTGQRREQSVTRAELHEEEQDE
ARGIAKYNPLADWTESDVWAYLNAFDVPVNPLHARGYPSIGCEPCTRAIRPGEDSRAGRWWWESRDTKECGLHITTITPI
PADAVAGATH
>Mature_249_residues
STATATALTPELAAKVERLDALLAQIGARHEKVKFASSLAAEDMLLTHAILSKGARIGIFSLNTGRLHAETLGMIDRVCE
RYGYEIEQFHPLQDAVDQYVAEHGLNAFYESVELRKSCCHIRKVEPLNRALADVGAWVTGQRREQSVTRAELHEEEQDEA
RGIAKYNPLADWTESDVWAYLNAFDVPVNPLHARGYPSIGCEPCTRAIRPGEDSRAGRWWWESRDTKECGLHITTITPIP
ADAVAGATH

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=200, Percent_Identity=31, Blast_Score=81, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6325425, Length=115, Percent_Identity=42.6086956521739, Blast_Score=90, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011798
- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 27776; Mature: 27644

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTATATALTPELAAKVERLDALLAQIGARHEKVKFASSLAAEDMLLTHAILSKGARIGI
CCCCHHHHHCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
FSLNTGRLHAETLGMIDRVCERYGYEIEQFHPLQDAVDQYVAEHGLNAFYESVELRKSCC
EECCCCCHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HIRKVEPLNRALADVGAWVTGQRREQSVTRAELHEEEQDEARGIAKYNPLADWTESDVWA
HHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCHHHH
YLNAFDVPVNPLHARGYPSIGCEPCTRAIRPGEDSRAGRWWWESRDTKECGLHITTITPI
HHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHCEEEEEECCC
PADAVAGATH
CCHHHCCCCC
>Mature Secondary Structure 
STATATALTPELAAKVERLDALLAQIGARHEKVKFASSLAAEDMLLTHAILSKGARIGI
CCCHHHHHCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
FSLNTGRLHAETLGMIDRVCERYGYEIEQFHPLQDAVDQYVAEHGLNAFYESVELRKSCC
EECCCCCHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HIRKVEPLNRALADVGAWVTGQRREQSVTRAELHEEEQDEARGIAKYNPLADWTESDVWA
HHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCHHHH
YLNAFDVPVNPLHARGYPSIGCEPCTRAIRPGEDSRAGRWWWESRDTKECGLHITTITPI
HHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHCEEEEEECCC
PADAVAGATH
CCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]