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The map label for this gene is cobQ [H]

Identifier: 78067246

GI number: 78067246

Start: 2892543

End: 2894078

Strand: Reverse

Name: cobQ [H]

Synonym: Bcep18194_A5777

Alternate gene names: 78067246

Gene position: 2894078-2892543 (Counterclockwise)

Preceding gene: 78067251

Following gene: 78067245

Centisome position: 78.34

GC content: 70.77

Gene sequence:

>1536_bases
ATGCGGCCTTTGCTTCGCGACGACCTTTACACGATGAATGCACCCGAGCCGCGGCCGCGCGGCACGCTGATGATCCAGGG
CACCACGTCCGACGCGGGCAAGAGCACGCTGGTTGCGGGCCTGTGCCGGCTGGCCCGCCGCGCCGGCGCGCGCGTTGCGC
CGTTCAAGCCGCAGAACATGGCGCTCAACAGCGCGGTGACGGCCGACGGCGGCGAGATCGGCCGCGCGCAGGCGCTGCAG
GCACTGGCCGCGGGCGTCGCGCCGCACACGGATTTCAACCCCGTGCTGCTGAAGCCGACGAGCGACCGCGGCGCGCAGGT
GATCATTCACGGCAAGGCGCGCATGAACCTCAATGCGCGTGCGTATCACGACTACAAGCCGGTCGCGTTCGACGCGGTGC
TCGAGTCGTACGCGCGCCTGCGCGCCGACTACGACACGGTGATCGTCGAAGGCGCGGGCAGCCCGGCGGAGATCAACCTG
CGCGAGGGCGACATCGCGAACATGGGATTTGCCGAACGCGTCGACTGCCCGGTCGTGCTGGTCGCCGACATCGACCGCGG
CGGCGTGTTCGCACACCTGGTCGGCACGCTCGCGTGCCTGTCGGACAGCGAGCGCGCGCGCGTGCGCGGCTTCGTGATTA
ACCGCTTCCGCGGCGATTTCAAGCTGCTCGAACCGGGGCTCGACTGGCTGCGCGCGCAGACGGGCAAGCCCGTGTTCGGC
GTGCTGCCGTACCTGCACGGCCTGCTGCTCGACGCCGAGGACATGCTGCCCGCACAGGCGCGCAGCGCCGCCGCACGCGG
CGACGCCGGCGTGCTGCGCGTCGTCGTGCCGGCGCTGCCGCGCATCAGCAACCACACCGATTTCGATCCGCTGCGCGCGC
ATCCGCAGGTCGAATTCACGTACTGGAAGAGCGGCCCCGTGCCGGACGCCGACCTGCTGATCCTGCCCGGGTCGAAGAGC
GTGCAGCGCGACCTCGCATGGCTGCGCGACGCAGGCTGGGACACGCTGATCCGTCGCCACCTGCGCTACGGCGGCAAGGT
GATCGGGATCTGCGGCGGGATGCAGATGCTTGGCCGCACGCTCGACGATCCGCTCGGCCTCGAAGGCGCGCCCGGTAGCG
TGCCGGGGCTCGGGCTGCTCGATTTCGGCACGACGCTGCAGCCCGACAAGACACTGAAGAACGTGACGGGACATCTCGCG
CTGCCGGGCGGGGCCGCGGTACACGGCTACGAGATCCACATGGGCGATACGCACGGGCCTGCGCTTGCTTCTCCCGCGCT
CGCGTTGGCAGCCGACGCCGCGCAGGACGGCACGCGCCCCGACGGCGCGGTGTCCGACGATGGCCAGATCCTCGCGACCT
ACGTGCACGGGCTGTTCGACTCGCCCGACGCCTGCGCGGCGCTGCTCGCGTGGGCCGGGCTCGACGGCGCGGAACGAATC
GACTATCCGGCGCTGCGCGAGGCATCGCTCGAGCGGCTGGCCGACACCTTCGCCGACCATCTCGACCTCGACGCGCTGTA
CGCCGAGTTTCGTTGA

Upstream 100 bases:

>100_bases
TGCGCGCTCTTGCCCGAACGCGCGCCGCCGAGGACGAAGGTGAGGTCGTGCGGAATCATCGCGTGATTGTAACGGCGCGG
GCATACCGACGCGGGGGATA

Downstream 100 bases:

>100_bases
CGCGGGTTGGGCCGTGCTCGCTTTTTCCGCCGGATCGCGTACAACACAGGAGGGCGGATGTCCGCCTGGAGGAGTGCGAC
GATGAAGGCTCGATGGTGGT

Product: cobyric acid synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 511; Mature: 511

Protein sequence:

>511_residues
MRPLLRDDLYTMNAPEPRPRGTLMIQGTTSDAGKSTLVAGLCRLARRAGARVAPFKPQNMALNSAVTADGGEIGRAQALQ
ALAAGVAPHTDFNPVLLKPTSDRGAQVIIHGKARMNLNARAYHDYKPVAFDAVLESYARLRADYDTVIVEGAGSPAEINL
REGDIANMGFAERVDCPVVLVADIDRGGVFAHLVGTLACLSDSERARVRGFVINRFRGDFKLLEPGLDWLRAQTGKPVFG
VLPYLHGLLLDAEDMLPAQARSAAARGDAGVLRVVVPALPRISNHTDFDPLRAHPQVEFTYWKSGPVPDADLLILPGSKS
VQRDLAWLRDAGWDTLIRRHLRYGGKVIGICGGMQMLGRTLDDPLGLEGAPGSVPGLGLLDFGTTLQPDKTLKNVTGHLA
LPGGAAVHGYEIHMGDTHGPALASPALALAADAAQDGTRPDGAVSDDGQILATYVHGLFDSPDACAALLAWAGLDGAERI
DYPALREASLERLADTFADHLDLDALYAEFR

Sequences:

>Translated_511_residues
MRPLLRDDLYTMNAPEPRPRGTLMIQGTTSDAGKSTLVAGLCRLARRAGARVAPFKPQNMALNSAVTADGGEIGRAQALQ
ALAAGVAPHTDFNPVLLKPTSDRGAQVIIHGKARMNLNARAYHDYKPVAFDAVLESYARLRADYDTVIVEGAGSPAEINL
REGDIANMGFAERVDCPVVLVADIDRGGVFAHLVGTLACLSDSERARVRGFVINRFRGDFKLLEPGLDWLRAQTGKPVFG
VLPYLHGLLLDAEDMLPAQARSAAARGDAGVLRVVVPALPRISNHTDFDPLRAHPQVEFTYWKSGPVPDADLLILPGSKS
VQRDLAWLRDAGWDTLIRRHLRYGGKVIGICGGMQMLGRTLDDPLGLEGAPGSVPGLGLLDFGTTLQPDKTLKNVTGHLA
LPGGAAVHGYEIHMGDTHGPALASPALALAADAAQDGTRPDGAVSDDGQILATYVHGLFDSPDACAALLAWAGLDGAERI
DYPALREASLERLADTFADHLDLDALYAEFR
>Mature_511_residues
MRPLLRDDLYTMNAPEPRPRGTLMIQGTTSDAGKSTLVAGLCRLARRAGARVAPFKPQNMALNSAVTADGGEIGRAQALQ
ALAAGVAPHTDFNPVLLKPTSDRGAQVIIHGKARMNLNARAYHDYKPVAFDAVLESYARLRADYDTVIVEGAGSPAEINL
REGDIANMGFAERVDCPVVLVADIDRGGVFAHLVGTLACLSDSERARVRGFVINRFRGDFKLLEPGLDWLRAQTGKPVFG
VLPYLHGLLLDAEDMLPAQARSAAARGDAGVLRVVVPALPRISNHTDFDPLRAHPQVEFTYWKSGPVPDADLLILPGSKS
VQRDLAWLRDAGWDTLIRRHLRYGGKVIGICGGMQMLGRTLDDPLGLEGAPGSVPGLGLLDFGTTLQPDKTLKNVTGHLA
LPGGAAVHGYEIHMGDTHGPALASPALALAADAAQDGTRPDGAVSDDGQILATYVHGLFDSPDACAALLAWAGLDGAERI
DYPALREASLERLADTFADHLDLDALYAEFR

Specific function: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation [H]

COG id: COG1492

COG function: function code H; Cobyric acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR017929
- InterPro:   IPR004459
- InterPro:   IPR011698 [H]

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]

EC number: NA

Molecular weight: Translated: 54506; Mature: 54506

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPLLRDDLYTMNAPEPRPRGTLMIQGTTSDAGKSTLVAGLCRLARRAGARVAPFKPQNM
CCCCCCCCCEECCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
ALNSAVTADGGEIGRAQALQALAAGVAPHTDFNPVLLKPTSDRGAQVIIHGKARMNLNAR
EECCEEECCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCEEEEECCEEECCCCE
AYHDYKPVAFDAVLESYARLRADYDTVIVEGAGSPAEINLREGDIANMGFAERVDCPVVL
EECCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCCCCCCCHHHCCCCEEE
VADIDRGGVFAHLVGTLACLSDSERARVRGFVINRFRGDFKLLEPGLDWLRAQTGKPVFG
EEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEHHCCHHHHHHCCCCCHHH
VLPYLHGLLLDAEDMLPAQARSAAARGDAGVLRVVVPALPRISNHTDFDPLRAHPQVEFT
HHHHHHHHHHCHHHHCCHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEE
YWKSGPVPDADLLILPGSKSVQRDLAWLRDAGWDTLIRRHLRYGGKVIGICGGMQMLGRT
EECCCCCCCCCEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEEEECCHHHHHHH
LDDPLGLEGAPGSVPGLGLLDFGTTLQPDKTLKNVTGHLALPGGAAVHGYEIHMGDTHGP
CCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHCCCEEECCCCCEEEEEEEEECCCCCC
ALASPALALAADAAQDGTRPDGAVSDDGQILATYVHGLFDSPDACAALLAWAGLDGAERI
CHHCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCHHHC
DYPALREASLERLADTFADHLDLDALYAEFR
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHCC
>Mature Secondary Structure
MRPLLRDDLYTMNAPEPRPRGTLMIQGTTSDAGKSTLVAGLCRLARRAGARVAPFKPQNM
CCCCCCCCCEECCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
ALNSAVTADGGEIGRAQALQALAAGVAPHTDFNPVLLKPTSDRGAQVIIHGKARMNLNAR
EECCEEECCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCEEEEECCEEECCCCE
AYHDYKPVAFDAVLESYARLRADYDTVIVEGAGSPAEINLREGDIANMGFAERVDCPVVL
EECCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCCCCCCCHHHCCCCEEE
VADIDRGGVFAHLVGTLACLSDSERARVRGFVINRFRGDFKLLEPGLDWLRAQTGKPVFG
EEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEHHCCHHHHHHCCCCCHHH
VLPYLHGLLLDAEDMLPAQARSAAARGDAGVLRVVVPALPRISNHTDFDPLRAHPQVEFT
HHHHHHHHHHCHHHHCCHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEE
YWKSGPVPDADLLILPGSKSVQRDLAWLRDAGWDTLIRRHLRYGGKVIGICGGMQMLGRT
EECCCCCCCCCEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEEEECCHHHHHHH
LDDPLGLEGAPGSVPGLGLLDFGTTLQPDKTLKNVTGHLALPGGAAVHGYEIHMGDTHGP
CCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHCCCEEECCCCCEEEEEEEEECCCCCC
ALASPALALAADAAQDGTRPDGAVSDDGQILATYVHGLFDSPDACAALLAWAGLDGAERI
CHHCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCHHHC
DYPALREASLERLADTFADHLDLDALYAEFR
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA