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The map label for this gene is panC

Identifier: 78067242

GI number: 78067242

Start: 2889553

End: 2890392

Strand: Direct

Name: panC

Synonym: Bcep18194_A5773

Alternate gene names: 78067242

Gene position: 2889553-2890392 (Clockwise)

Preceding gene: 78067241

Following gene: 78067243

Centisome position: 78.22

GC content: 66.55

Gene sequence:

>840_bases
ATGAAAGTCATCAGCTCGATCCATGAACTGCGCGACCAGCTGCGCGGACAGAACCGCACGGCGTTCGTGCCGACGATGGG
CAACCTGCACGAAGGGCACCTGTCGCTGATGCGCCTCGCGCGCCAGCACGGCGACCCGGTCGTGGCGAGCATCTTCGTCA
ACCGGCTGCAATTCGGCCCGAACGAGGATTTCGACAAGTATCCGCGCACGCTCCAGGACGATATCGAGAAGCTGCAGAAG
GAAAACGTCTACGTGCTGTTCGCGCCGACCGAGCGCGACATGTACCCGGAACCGCAGGAATACCGCGTGCTGCCGCCGGA
CGATCTCGGCGGGATCCTCGAAGGGGAATTCCGGCCCGGCTTCTTCACCGGCGTGTGCACCGTCGTGACGAAGCTGATGG
CCTGCGTGCAGCCGCGCGTCGCCGTGTTCGGCAAGAAGGACTACCAGCAGTTGATGATCGTGCGCCGCATGTGCCAGCAG
CTCGCGCTGCCGGTCGACATCATCGCCGCCGAAACCGTGCGTGACGAGGACGGCCTCGCGCTGTCGTCGCGCAATCGCTA
CCTGTCGGCCGACGAGCGCAGCGAAGCGCCCGAACTCGCGAAGACGCTGCAGCGCATCCGCGAAAGCGTGCTCGGCGGCG
AGCACGACCTCGGCAAGCTCGAAGAAATGGCCCGCACGCATCTGGCCGGCCGCGGCTGGGCGCCCGACTACATCTCGATC
CGCCGCCGCGCGAACCTGATCGCGCCGGACGCGGCCCAGCTCGAAGCCGGCGAACCGCTCGTCGTCGTCGCAGCCGCGAA
GCTCGGCGCGACGCGCCTCATCGACAACCTGGAAATCTGA

Upstream 100 bases:

>100_bases
CGCCCGATGCGCCGCCCGCGCGCCGGCGTTCTCCGCTTCGACCCCGACGCCGCTGCTGCGGCGCCAACGCGCGCCAGCGC
GAGGAACCCGCTACCCGATC

Downstream 100 bases:

>100_bases
CGGGCCGCCCCGCCCGCGCCTCTCACGCATCACGGAGACACCATGCAGCGCCACATGCTCAAATCGAAGATCCACCGCGC
GGCCGTCACGCACTGCGAGC

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MKVISSIHELRDQLRGQNRTAFVPTMGNLHEGHLSLMRLARQHGDPVVASIFVNRLQFGPNEDFDKYPRTLQDDIEKLQK
ENVYVLFAPTERDMYPEPQEYRVLPPDDLGGILEGEFRPGFFTGVCTVVTKLMACVQPRVAVFGKKDYQQLMIVRRMCQQ
LALPVDIIAAETVRDEDGLALSSRNRYLSADERSEAPELAKTLQRIRESVLGGEHDLGKLEEMARTHLAGRGWAPDYISI
RRRANLIAPDAAQLEAGEPLVVVAAAKLGATRLIDNLEI

Sequences:

>Translated_279_residues
MKVISSIHELRDQLRGQNRTAFVPTMGNLHEGHLSLMRLARQHGDPVVASIFVNRLQFGPNEDFDKYPRTLQDDIEKLQK
ENVYVLFAPTERDMYPEPQEYRVLPPDDLGGILEGEFRPGFFTGVCTVVTKLMACVQPRVAVFGKKDYQQLMIVRRMCQQ
LALPVDIIAAETVRDEDGLALSSRNRYLSADERSEAPELAKTLQRIRESVLGGEHDLGKLEEMARTHLAGRGWAPDYISI
RRRANLIAPDAAQLEAGEPLVVVAAAKLGATRLIDNLEI
>Mature_279_residues
MKVISSIHELRDQLRGQNRTAFVPTMGNLHEGHLSLMRLARQHGDPVVASIFVNRLQFGPNEDFDKYPRTLQDDIEKLQK
ENVYVLFAPTERDMYPEPQEYRVLPPDDLGGILEGEFRPGFFTGVCTVVTKLMACVQPRVAVFGKKDYQQLMIVRRMCQQ
LALPVDIIAAETVRDEDGLALSSRNRYLSADERSEAPELAKTLQRIRESVLGGEHDLGKLEEMARTHLAGRGWAPDYISI
RRRANLIAPDAAQLEAGEPLVVVAAAKLGATRLIDNLEI

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate [H]

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786325, Length=283, Percent_Identity=43.4628975265018, Blast_Score=217, Evalue=8e-58,
Organism=Saccharomyces cerevisiae, GI6322046, Length=302, Percent_Identity=36.4238410596026, Blast_Score=157, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR003721
- InterPro:   IPR014729 [H]

Pfam domain/function: PF02569 Pantoate_ligase [H]

EC number: =6.3.2.1 [H]

Molecular weight: Translated: 31343; Mature: 31343

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVISSIHELRDQLRGQNRTAFVPTMGNLHEGHLSLMRLARQHGDPVVASIFVNRLQFGP
CHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
NEDFDKYPRTLQDDIEKLQKENVYVLFAPTERDMYPEPQEYRVLPPDDLGGILEGEFRPG
CCCHHHCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCEECCCCCCCCCCCCCCCCC
FFTGVCTVVTKLMACVQPRVAVFGKKDYQQLMIVRRMCQQLALPVDIIAAETVRDEDGLA
HHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCE
LSSRNRYLSADERSEAPELAKTLQRIRESVLGGEHDLGKLEEMARTHLAGRGWAPDYISI
ECCCCCEECCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHH
RRRANLIAPDAAQLEAGEPLVVVAAAKLGATRLIDNLEI
HHHCCCCCCCHHHHCCCCCEEEEEEHHHHHHHHHHCCCC
>Mature Secondary Structure
MKVISSIHELRDQLRGQNRTAFVPTMGNLHEGHLSLMRLARQHGDPVVASIFVNRLQFGP
CHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
NEDFDKYPRTLQDDIEKLQKENVYVLFAPTERDMYPEPQEYRVLPPDDLGGILEGEFRPG
CCCHHHCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCEECCCCCCCCCCCCCCCCC
FFTGVCTVVTKLMACVQPRVAVFGKKDYQQLMIVRRMCQQLALPVDIIAAETVRDEDGLA
HHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCE
LSSRNRYLSADERSEAPELAKTLQRIRESVLGGEHDLGKLEEMARTHLAGRGWAPDYISI
ECCCCCEECCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHH
RRRANLIAPDAAQLEAGEPLVVVAAAKLGATRLIDNLEI
HHHCCCCCCCHHHHCCCCCEEEEEEHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA