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The map label for this gene is eco [H]

Identifier: 78067182

GI number: 78067182

Start: 2820617

End: 2821117

Strand: Reverse

Name: eco [H]

Synonym: Bcep18194_A5713

Alternate gene names: 78067182

Gene position: 2821117-2820617 (Counterclockwise)

Preceding gene: 78067184

Following gene: 78067180

Centisome position: 76.37

GC content: 67.47

Gene sequence:

>501_bases
ATGAAATTCGCGATCCGGGCCGCGCTGGCCGCCTTCTGCGTGACGACTGCCGCCGCTTGCGTGGCCGCGCCTGCCTCGGC
GCCTGCCGTGACGGCCGAGTCGATCAAGATGTTTCCGCAGGCAGCGGCCGGCCAGCAGCGCGTCGTGATCGCGCTGCCCG
CGCTCGAGAACGAAGGCGATGCGCGCGTCGAGCTGATGATCGGCAAGACGCTGCAGACCGACTGCAACCAGCAGTGGTTC
GGCGGCGAGCTGACCGCCGAGGACGTGAAGGGCTGGGGCTATACGTATTACCAGCTCACCGACGTGAAGGGGCCGGCATC
GACGCTGATGGCATGCCCGGGCCAGGCGCCGCAGCAACGGTTCGTGCAGGTGCGCGGTGACGGCCAGCTGCTGCGCTACA
ACAGCCGCCTGCCGCTCGTCGTCTATGTGCCGGACGGCTTTGATGTGCGCTATCGCGTGTGGCATGCGTCGAAGGACGTG
CAGCACGCAGCGAAGCAGTAA

Upstream 100 bases:

>100_bases
GCCAGCTGTTTGCAATTGTGTCGTCAAATTACAGCGCCGTAAGGTCCTGCGACGAAAGTGTTAGCATCCGGGGCTCATTT
TGTTTTTCAGGAGTACATCG

Downstream 100 bases:

>100_bases
CGTAACGGTGCGGCGGTAGCGTCCTGCCGCTACGCGCCGCCCGTGCCGACGAGCGCTGGCCACGCAGCCAGCGCGGCTTG
TGCGACGGCCTCCAGATCGC

Product: ecotin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MKFAIRAALAAFCVTTAAACVAAPASAPAVTAESIKMFPQAAAGQQRVVIALPALENEGDARVELMIGKTLQTDCNQQWF
GGELTAEDVKGWGYTYYQLTDVKGPASTLMACPGQAPQQRFVQVRGDGQLLRYNSRLPLVVYVPDGFDVRYRVWHASKDV
QHAAKQ

Sequences:

>Translated_166_residues
MKFAIRAALAAFCVTTAAACVAAPASAPAVTAESIKMFPQAAAGQQRVVIALPALENEGDARVELMIGKTLQTDCNQQWF
GGELTAEDVKGWGYTYYQLTDVKGPASTLMACPGQAPQQRFVQVRGDGQLLRYNSRLPLVVYVPDGFDVRYRVWHASKDV
QHAAKQ
>Mature_166_residues
MKFAIRAALAAFCVTTAAACVAAPASAPAVTAESIKMFPQAAAGQQRVVIALPALENEGDARVELMIGKTLQTDCNQQWF
GGELTAEDVKGWGYTYYQLTDVKGPASTLMACPGQAPQQRFVQVRGDGQLLRYNSRLPLVVYVPDGFDVRYRVWHASKDV
QHAAKQ

Specific function: General inhibitor of family S1 serine proteases [H]

COG id: COG4574

COG function: function code R; Serine protease inhibitor ecotin

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protease inhibitor I11 (ecotin) family [H]

Homologues:

Organism=Escherichia coli, GI1788538, Length=164, Percent_Identity=45.1219512195122, Blast_Score=141, Evalue=3e-35,

Paralogues:

None

Copy number: 260 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005658
- InterPro:   IPR023189
- InterPro:   IPR023084 [H]

Pfam domain/function: PF03974 Ecotin [H]

EC number: NA

Molecular weight: Translated: 18005; Mature: 18005

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFAIRAALAAFCVTTAAACVAAPASAPAVTAESIKMFPQAAAGQQRVVIALPALENEGD
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCEEEEEEECCCCCCC
ARVELMIGKTLQTDCNQQWFGGELTAEDVKGWGYTYYQLTDVKGPASTLMACPGQAPQQR
CEEEEEECCCCCCCCCCCCCCCCCCHHHCCCCCEEEEEEEECCCCHHHHEECCCCCCCHH
FVQVRGDGQLLRYNSRLPLVVYVPDGFDVRYRVWHASKDVQHAAKQ
EEEECCCCEEEEECCCCCEEEECCCCCCEEEEEEECCCHHHHHHCC
>Mature Secondary Structure
MKFAIRAALAAFCVTTAAACVAAPASAPAVTAESIKMFPQAAAGQQRVVIALPALENEGD
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCEEEEEEECCCCCCC
ARVELMIGKTLQTDCNQQWFGGELTAEDVKGWGYTYYQLTDVKGPASTLMACPGQAPQQR
CEEEEEECCCCCCCCCCCCCCCCCCHHHCCCCCEEEEEEEECCCCHHHHEECCCCCCCHH
FVQVRGDGQLLRYNSRLPLVVYVPDGFDVRYRVWHASKDVQHAAKQ
EEEECCCCEEEEECCCCCEEEECCCCCCEEEEEEECCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA