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The map label for this gene is speE [H]

Identifier: 78067151

GI number: 78067151

Start: 2788458

End: 2789375

Strand: Reverse

Name: speE [H]

Synonym: Bcep18194_A5682

Alternate gene names: 78067151

Gene position: 2789375-2788458 (Counterclockwise)

Preceding gene: 78067153

Following gene: 78067150

Centisome position: 75.51

GC content: 67.21

Gene sequence:

>918_bases
ATGACCCGACTGATCAAGCGCGCGTCCGCCGAGGCGCGCGCGTCCAAGCGCAGCAAGCCGTCCGCCTACAACGGCTCCGA
AAAACTCCAGCCGCCGCGCGTGAAGCGCCGCCCGGAGATCGACGAACACGACGACGTGCCCGTGCTCGAAGCCCCGCGCA
AGCCGCGCTTCGCGCCCGTCACGTTCTCGGAAGAGGGCGGCGTGCGCTTCCTGCATTTCGGTACCGAATGGGTGCAGGGC
GCGATGCGGATTTCGAAGCCGCTGCATATCGAGCTCGAATACGCCCAGCAGATGATGGCGTGGCTGCTGTTCCTCGAAAC
GCCCGAGCGGGTCGTCCAGCTCGGGCTCGGCACCGGCGCGCTGACCAAGTTCTCGCACCGCTTCCTGCCGCACGCGAAGG
TCGAGGCCGTCGAGCTGAACCCGGCCGTAATCGTCGCCGCGCGCACGATGTTCGCGCTGCCACCCGACGATGCACGCCTC
GCCGTGCACGAAGCCGACGCGTGGGATTTCGTCAACGATCCGGCCAACCGCGGCACCACGGGCGCGATCCAGATCGACCT
GTACGACGCGACCGCGCGCGGCCCCGTGCTCGACAGCGTTTCGTTCTACCGCGCGGTGCGCGGCTGCCTCGCCGACGCGG
GCATCGCGACGATCAACCTGTTCGGCGATCATCCGAGCTTCGTGCGCAACATGAAGCACCTGAACGCGGCGTTTGATCAC
CGCGTGATCGCGCTGCCGGAAGTGCATGACGGCAACCGGATCGCGATCGCGTTCTCGGGCCCCGCGCTCGACGTGTCGTT
CGCGCAGCTCGACGAGCGTGCGAAGCTGATCGAGGACACGCTGAAGCTGCCCGCACGCAAGTGGGTGAAAGCTTTGAAAG
AAACGACCGGCGCGCGCGACGCTTCGTTCGCGATCTGA

Upstream 100 bases:

>100_bases
GTCGAAGTCATGCGCGGCCGGGCAGTCGGCGCGGCTTCGGCTCTGCACCAATGCTATCCTCTCGTCCGCTAAAACCAGCT
TCACCCAGCGAGATTCACAC

Downstream 100 bases:

>100_bases
CGCTTCATGCACCGGCGGCATGCCGGTGCAACCACGCGACAAGGGGCGGATCACCTCGGGTTCGCCCCCGCTTGACCGCG
TGCTCGCGGCTCCTATACTG

Product: spermidine synthase-like

Products: NA

Alternate protein names: Putrescine aminopropyltransferase; PAPT; SPDSY [H]

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MTRLIKRASAEARASKRSKPSAYNGSEKLQPPRVKRRPEIDEHDDVPVLEAPRKPRFAPVTFSEEGGVRFLHFGTEWVQG
AMRISKPLHIELEYAQQMMAWLLFLETPERVVQLGLGTGALTKFSHRFLPHAKVEAVELNPAVIVAARTMFALPPDDARL
AVHEADAWDFVNDPANRGTTGAIQIDLYDATARGPVLDSVSFYRAVRGCLADAGIATINLFGDHPSFVRNMKHLNAAFDH
RVIALPEVHDGNRIAIAFSGPALDVSFAQLDERAKLIEDTLKLPARKWVKALKETTGARDASFAI

Sequences:

>Translated_305_residues
MTRLIKRASAEARASKRSKPSAYNGSEKLQPPRVKRRPEIDEHDDVPVLEAPRKPRFAPVTFSEEGGVRFLHFGTEWVQG
AMRISKPLHIELEYAQQMMAWLLFLETPERVVQLGLGTGALTKFSHRFLPHAKVEAVELNPAVIVAARTMFALPPDDARL
AVHEADAWDFVNDPANRGTTGAIQIDLYDATARGPVLDSVSFYRAVRGCLADAGIATINLFGDHPSFVRNMKHLNAAFDH
RVIALPEVHDGNRIAIAFSGPALDVSFAQLDERAKLIEDTLKLPARKWVKALKETTGARDASFAI
>Mature_304_residues
TRLIKRASAEARASKRSKPSAYNGSEKLQPPRVKRRPEIDEHDDVPVLEAPRKPRFAPVTFSEEGGVRFLHFGTEWVQGA
MRISKPLHIELEYAQQMMAWLLFLETPERVVQLGLGTGALTKFSHRFLPHAKVEAVELNPAVIVAARTMFALPPDDARLA
VHEADAWDFVNDPANRGTTGAIQIDLYDATARGPVLDSVSFYRAVRGCLADAGIATINLFGDHPSFVRNMKHLNAAFDHR
VIALPEVHDGNRIAIAFSGPALDVSFAQLDERAKLIEDTLKLPARKWVKALKETTGARDASFAI

Specific function: Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor [H]

COG id: COG0421

COG function: function code E; Spermidine synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the spermidine/spermine synthase family [H]

Homologues:

Organism=Homo sapiens, GI42542405, Length=221, Percent_Identity=25.7918552036199, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI42542403, Length=221, Percent_Identity=25.7918552036199, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI55956895, Length=221, Percent_Identity=25.7918552036199, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001045 [H]

Pfam domain/function: PF01564 Spermine_synth [H]

EC number: =2.5.1.16 [H]

Molecular weight: Translated: 33775; Mature: 33644

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRLIKRASAEARASKRSKPSAYNGSEKLQPPRVKRRPEIDEHDDVPVLEAPRKPRFAPV
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
TFSEEGGVRFLHFGTEWVQGAMRISKPLHIELEYAQQMMAWLLFLETPERVVQLGLGTGA
EECCCCCEEEEECCHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCHHHHHHHCCCCCH
LTKFSHRFLPHAKVEAVELNPAVIVAARTMFALPPDDARLAVHEADAWDFVNDPANRGTT
HHHHHHHCCCCCCEEEEECCCEEEEEEHHEEECCCCCCEEEEEECCCCCCCCCCCCCCCC
GAIQIDLYDATARGPVLDSVSFYRAVRGCLADAGIATINLFGDHPSFVRNMKHLNAAFDH
EEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHCC
RVIALPEVHDGNRIAIAFSGPALDVSFAQLDERAKLIEDTLKLPARKWVKALKETTGARD
EEEECCCCCCCCEEEEEECCCCCEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCC
ASFAI
CCCCC
>Mature Secondary Structure 
TRLIKRASAEARASKRSKPSAYNGSEKLQPPRVKRRPEIDEHDDVPVLEAPRKPRFAPV
CHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
TFSEEGGVRFLHFGTEWVQGAMRISKPLHIELEYAQQMMAWLLFLETPERVVQLGLGTGA
EECCCCCEEEEECCHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCHHHHHHHCCCCCH
LTKFSHRFLPHAKVEAVELNPAVIVAARTMFALPPDDARLAVHEADAWDFVNDPANRGTT
HHHHHHHCCCCCCEEEEECCCEEEEEEHHEEECCCCCCEEEEEECCCCCCCCCCCCCCCC
GAIQIDLYDATARGPVLDSVSFYRAVRGCLADAGIATINLFGDHPSFVRNMKHLNAAFDH
EEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHCC
RVIALPEVHDGNRIAIAFSGPALDVSFAQLDERAKLIEDTLKLPARKWVKALKETTGARD
EEEECCCCCCCCEEEEEECCCCCEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCC
ASFAI
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]