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The map label for this gene is tpiA

Identifier: 78067048

GI number: 78067048

Start: 2675845

End: 2676600

Strand: Reverse

Name: tpiA

Synonym: Bcep18194_A5579

Alternate gene names: 78067048

Gene position: 2676600-2675845 (Counterclockwise)

Preceding gene: 78067049

Following gene: 78067047

Centisome position: 72.46

GC content: 69.31

Gene sequence:

>756_bases
ATGTCGAAACAGAGAACTAAGCGTGTGATCGGCAACTGGAAGATGCACGGCCGGCTGGCCGGCAACCAGGCGTTGCTGAA
CGAAGTGGTGCAGGGCGCGGGCGCGGTGGCGGCCGAAACGTCGATCGGCGTGTGCGTGCCGTTCCCGTATCTCGCGCAGG
TTCAGGCGCAGCTCGACGGCGGCCGTGTCGCCTGGGGTGCGCAGGACGTGTCGGCGCACGAACAGGGCGCGTTCACCGGT
GAAGTCGCGGCCGCGATGGTCGCGGAGTTCGGCGCACGCTATGCGATCGTCGGTCACTCGGAGCGCCGCGCGTATCACGG
CGAACGCAACGAGACGGTCGCCGCGAAGACGCAGCGCGCGCTCGCAGCGGGGCTCACGCCAGTCGTGTGCGTTGGCGAGA
CGCTCGACGAGCGCGAGTCGGGTGCGACCGAGCAGGTGGTCGGTGCGCAGCTCGACGCAGTGCTGGCCGTGCTGACGGCT
GACGAAGCGACGCGCATCGTCGTCGCATACGAGCCGGTCTGGGCGATCGGCACGGGCAAGAGCGCGACGTCGGCGCAGGC
ACAGGACGTGCACGCGTTCCTGCGTGCGCGTCTCGCGGCAAAGGGTGCGGCGGACGTGTCCGTGCTGTACGGCGGCAGCG
TTAAGCCGGACAACGCGGAAGAGCTGTTTGCGCAGCCGGACATCGACGGCGGCCTGATCGGCGGCGCGTCGCTGAAGGCG
GAAGATTTCCTGGCGATCTGCCGGGCCGCGCGTTGA

Upstream 100 bases:

>100_bases
TCAAGCCGCGCGCAGTAAAATCGCCGGTTTGCTTCGCCAGATCAAACCTGACGGCCGGTTTCCGGCACGTTAATGACCAA
GCGGTGACGAGACAGACACG

Downstream 100 bases:

>100_bases
GCGGTCCGGGATCGAATTGAACCATGACGGTGGCCGGTCGTTCCGGTCGCCTGATCCATTCGGGTGGGTGTGATGCTGTT
ATTCAAGACGCTGATTATTG

Product: triosephosphate isomerase

Products: NA

Alternate protein names: TIM; Triose-phosphate isomerase [H]

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MSKQRTKRVIGNWKMHGRLAGNQALLNEVVQGAGAVAAETSIGVCVPFPYLAQVQAQLDGGRVAWGAQDVSAHEQGAFTG
EVAAAMVAEFGARYAIVGHSERRAYHGERNETVAAKTQRALAAGLTPVVCVGETLDERESGATEQVVGAQLDAVLAVLTA
DEATRIVVAYEPVWAIGTGKSATSAQAQDVHAFLRARLAAKGAADVSVLYGGSVKPDNAEELFAQPDIDGGLIGGASLKA
EDFLAICRAAR

Sequences:

>Translated_251_residues
MSKQRTKRVIGNWKMHGRLAGNQALLNEVVQGAGAVAAETSIGVCVPFPYLAQVQAQLDGGRVAWGAQDVSAHEQGAFTG
EVAAAMVAEFGARYAIVGHSERRAYHGERNETVAAKTQRALAAGLTPVVCVGETLDERESGATEQVVGAQLDAVLAVLTA
DEATRIVVAYEPVWAIGTGKSATSAQAQDVHAFLRARLAAKGAADVSVLYGGSVKPDNAEELFAQPDIDGGLIGGASLKA
EDFLAICRAAR
>Mature_250_residues
SKQRTKRVIGNWKMHGRLAGNQALLNEVVQGAGAVAAETSIGVCVPFPYLAQVQAQLDGGRVAWGAQDVSAHEQGAFTGE
VAAAMVAEFGARYAIVGHSERRAYHGERNETVAAKTQRALAAGLTPVVCVGETLDERESGATEQVVGAQLDAVLAVLTAD
EATRIVVAYEPVWAIGTGKSATSAQAQDVHAFLRARLAAKGAADVSVLYGGSVKPDNAEELFAQPDIDGGLIGGASLKAE
DFLAICRAAR

Specific function: Plays an important role in several metabolic pathways. [C]

COG id: COG0149

COG function: function code G; Triosephosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the triosephosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI4507645, Length=255, Percent_Identity=41.9607843137255, Blast_Score=181, Evalue=5e-46,
Organism=Homo sapiens, GI226529917, Length=255, Percent_Identity=41.9607843137255, Blast_Score=181, Evalue=7e-46,
Organism=Escherichia coli, GI1790353, Length=250, Percent_Identity=48, Blast_Score=218, Evalue=3e-58,
Organism=Caenorhabditis elegans, GI17536593, Length=245, Percent_Identity=46.1224489795918, Blast_Score=191, Evalue=4e-49,
Organism=Saccharomyces cerevisiae, GI6320255, Length=251, Percent_Identity=40.2390438247012, Blast_Score=174, Evalue=8e-45,
Organism=Drosophila melanogaster, GI28572004, Length=244, Percent_Identity=43.8524590163934, Blast_Score=181, Evalue=4e-46,
Organism=Drosophila melanogaster, GI28572008, Length=244, Percent_Identity=43.8524590163934, Blast_Score=181, Evalue=5e-46,
Organism=Drosophila melanogaster, GI28572006, Length=244, Percent_Identity=43.8524590163934, Blast_Score=181, Evalue=5e-46,

Paralogues:

None

Copy number: 1120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR022896
- InterPro:   IPR000652
- InterPro:   IPR020861 [H]

Pfam domain/function: PF00121 TIM [H]

EC number: =5.3.1.1 [H]

Molecular weight: Translated: 26096; Mature: 25964

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS00171 TIM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKQRTKRVIGNWKMHGRLAGNQALLNEVVQGAGAVAAETSIGVCVPFPYLAQVQAQLDG
CCHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCEEECCCCCEEECCHHHHHHHHHCCC
GRVAWGAQDVSAHEQGAFTGEVAAAMVAEFGARYAIVGHSERRAYHGERNETVAAKTQRA
CEEEECCCCCCHHHCCCCHHHHHHHHHHHHCCCEEEEECCHHHHHCCCCCCCHHHHHHHH
LAAGLTPVVCVGETLDERESGATEQVVGAQLDAVLAVLTADEATRIVVAYEPVWAIGTGK
HHHCCCCEEEECCCHHHHHCCCHHHHHHHHHHHHHHHEECCCCEEEEEEECCEEEEECCC
SATSAQAQDVHAFLRARLAAKGAADVSVLYGGSVKPDNAEELFAQPDIDGGLIGGASLKA
CCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHCCCCCCCCEECCCCCCH
EDFLAICRAAR
HHHHHHHHCCC
>Mature Secondary Structure 
SKQRTKRVIGNWKMHGRLAGNQALLNEVVQGAGAVAAETSIGVCVPFPYLAQVQAQLDG
CHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCEEECCCCCEEECCHHHHHHHHHCCC
GRVAWGAQDVSAHEQGAFTGEVAAAMVAEFGARYAIVGHSERRAYHGERNETVAAKTQRA
CEEEECCCCCCHHHCCCCHHHHHHHHHHHHCCCEEEEECCHHHHHCCCCCCCHHHHHHHH
LAAGLTPVVCVGETLDERESGATEQVVGAQLDAVLAVLTADEATRIVVAYEPVWAIGTGK
HHHCCCCEEEECCCHHHHHCCCHHHHHHHHHHHHHHHEECCCCEEEEEEECCEEEEECCC
SATSAQAQDVHAFLRARLAAKGAADVSVLYGGSVKPDNAEELFAQPDIDGGLIGGASLKA
CCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHCCCCCCCCEECCCCCCH
EDFLAICRAAR
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA