BacMap

Definition	Burkholderia sp. 383 chromosome 1, complete genome.
Accession	NC_007510
Length	3,694,126

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The map label for this gene is fabG [H]

Identifier: 78066961

GI number: 78066961

Start: 2578959

End: 2579750

Strand: Reverse

Name: fabG [H]

Synonym: Bcep18194_A5492

Alternate gene names: 78066961

Gene position: 2579750-2578959 (Counterclockwise)

Preceding gene: 78066962

Following gene: 78066960

Centisome position: 69.83

GC content: 65.66

Gene sequence:

>792_bases
ATGTTGCTGAAGGACAAGATCGTCGTGATTTCAGGGATCGGGCCGGGGCTCGGCGTGAAGCTCGCTGTCGAAGCTGCACG
CGAGGGCGCGCGCGGCGTGGTCGTCGCCGCGCGCACGATGGAAAAGCTCGACGACGCCGAAGCGCGAATCCAAGCACTCG
GCGTCGATTGCGATGTGCTGAAGGTGAAGACCGACATCACCGACCGCGCACAATGCCGGCAGCTCGCGACGCAGGCCGTC
GAGCGCTTCGGCCGGATCGACGCGCTCGTGAACAGCGCATTCGTGCACGGCACGTTCCCGGAACCGGTGGAGGAGGCCGA
TCTCGATGGCTGGCGCGCGGTGTTCGACACCAACGTGTTCGGTACGATGGCGCTCACGCAGGAAGTCGTGCCGCACATGA
AGCGACAGAAGCGCGGCGCGATCGTGATGATCAACACGCAGGCGACCCGCAAGCCGTTTGCAGGGGAAGGCGGTTACGCT
GTATCGAAGGGCGCGCTCGCGGTTGCGGCAAAATACCTGGCGCGAGAACTCGGCGTGCACGGCATTCGCGCGAACAGCAT
CCACATGGGGTGGATGTGGGGCGTGCCGACCCAGACGTATTTCCGGCAGGCGGCCGCCGAGTACGGGATGACGGAAGAGC
AGATCATCGCGCCGATCGCGTCGAACATCGCGCTCGCGAAGCTGCCGACCGACGATGACTGCGCGCGTGCCGCACTGTTC
CTCGCGTCGGACTACGCGAACGCGGTGACGGGCGCGACGCTCGACGCGAATGGCGGCGATTTCATGCCCTGA

Upstream 100 bases:

>100_bases
GCAGCTCGCGCGCGACTTCGCCGCGTATCGCGCGCGGCACCTGCGGGCGGCAGGCTGACGGCCATTGCTCGCTAGATCAA
CGACAACCAGGAGACAACCC

Downstream 100 bases:

>100_bases
CGATGGAGCAAGGGAACATGCAGGACAACCACGAAACACAACATTTCTTTGCGTTCAACGGCGACGCGGACGGGCTGTGC
GCACTTCAGCAACTGCGGCT

Product: short chain dehydrogenase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MLLKDKIVVISGIGPGLGVKLAVEAAREGARGVVVAARTMEKLDDAEARIQALGVDCDVLKVKTDITDRAQCRQLATQAV
ERFGRIDALVNSAFVHGTFPEPVEEADLDGWRAVFDTNVFGTMALTQEVVPHMKRQKRGAIVMINTQATRKPFAGEGGYA
VSKGALAVAAKYLARELGVHGIRANSIHMGWMWGVPTQTYFRQAAAEYGMTEEQIIAPIASNIALAKLPTDDDCARAALF
LASDYANAVTGATLDANGGDFMP

Sequences:

>Translated_263_residues
MLLKDKIVVISGIGPGLGVKLAVEAAREGARGVVVAARTMEKLDDAEARIQALGVDCDVLKVKTDITDRAQCRQLATQAV
ERFGRIDALVNSAFVHGTFPEPVEEADLDGWRAVFDTNVFGTMALTQEVVPHMKRQKRGAIVMINTQATRKPFAGEGGYA
VSKGALAVAAKYLARELGVHGIRANSIHMGWMWGVPTQTYFRQAAAEYGMTEEQIIAPIASNIALAKLPTDDDCARAALF
LASDYANAVTGATLDANGGDFMP
>Mature_263_residues
MLLKDKIVVISGIGPGLGVKLAVEAAREGARGVVVAARTMEKLDDAEARIQALGVDCDVLKVKTDITDRAQCRQLATQAV
ERFGRIDALVNSAFVHGTFPEPVEEADLDGWRAVFDTNVFGTMALTQEVVPHMKRQKRGAIVMINTQATRKPFAGEGGYA
VSKGALAVAAKYLARELGVHGIRANSIHMGWMWGVPTQTYFRQAAAEYGMTEEQIIAPIASNIALAKLPTDDDCARAALF
LASDYANAVTGATLDANGGDFMP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=265, Percent_Identity=30.188679245283, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI19923817, Length=263, Percent_Identity=26.9961977186312, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI10190704, Length=262, Percent_Identity=28.6259541984733, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI5031737, Length=262, Percent_Identity=28.6259541984733, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI33667109, Length=191, Percent_Identity=30.8900523560209, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI7706318, Length=192, Percent_Identity=32.2916666666667, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI59889578, Length=202, Percent_Identity=29.2079207920792, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI126723191, Length=195, Percent_Identity=31.7948717948718, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI7705925, Length=261, Percent_Identity=27.5862068965517, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI15277342, Length=271, Percent_Identity=26.5682656826568, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI4503817, Length=180, Percent_Identity=28.3333333333333, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI4503301, Length=232, Percent_Identity=25.8620689655172, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI126723750, Length=266, Percent_Identity=26.3157894736842, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI7657478, Length=177, Percent_Identity=34.4632768361582, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI87082100, Length=267, Percent_Identity=31.0861423220974, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787335, Length=262, Percent_Identity=28.2442748091603, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1787905, Length=257, Percent_Identity=29.9610894941634, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1786812, Length=263, Percent_Identity=28.1368821292776, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1787526, Length=264, Percent_Identity=28.7878787878788, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87082160, Length=257, Percent_Identity=27.2373540856031, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1788459, Length=259, Percent_Identity=25.0965250965251, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI2367175, Length=258, Percent_Identity=28.2945736434109, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790717, Length=257, Percent_Identity=24.124513618677, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1789057, Length=261, Percent_Identity=26.0536398467433, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789378, Length=262, Percent_Identity=24.4274809160305, Blast_Score=61, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI17560676, Length=258, Percent_Identity=29.8449612403101, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17561402, Length=254, Percent_Identity=27.9527559055118, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71994600, Length=255, Percent_Identity=25.8823529411765, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=213, Percent_Identity=30.0469483568075, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17551412, Length=275, Percent_Identity=28.3636363636364, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71994604, Length=254, Percent_Identity=25.5905511811024, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=275, Percent_Identity=28.3636363636364, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17544670, Length=267, Percent_Identity=26.9662921348315, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=270, Percent_Identity=27.7777777777778, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17536025, Length=265, Percent_Identity=29.4339622641509, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=270, Percent_Identity=28.5185185185185, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17562910, Length=196, Percent_Identity=28.0612244897959, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=191, Percent_Identity=31.413612565445, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17536651, Length=265, Percent_Identity=27.5471698113208, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=269, Percent_Identity=26.7657992565056, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=268, Percent_Identity=26.865671641791, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI115534694, Length=260, Percent_Identity=25.3846153846154, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=267, Percent_Identity=25.8426966292135, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17531453, Length=197, Percent_Identity=31.4720812182741, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17568967, Length=192, Percent_Identity=28.125, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322227, Length=219, Percent_Identity=30.5936073059361, Blast_Score=72, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6324126, Length=262, Percent_Identity=27.8625954198473, Blast_Score=69, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6323882, Length=255, Percent_Identity=28.6274509803922, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322226, Length=115, Percent_Identity=34.7826086956522, Blast_Score=66, Evalue=6e-12,
Organism=Drosophila melanogaster, GI23397609, Length=266, Percent_Identity=30.8270676691729, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI21355319, Length=259, Percent_Identity=30.1158301158301, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28571526, Length=260, Percent_Identity=30.3846153846154, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI21357041, Length=260, Percent_Identity=28.8461538461538, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24644339, Length=259, Percent_Identity=26.6409266409266, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24643142, Length=261, Percent_Identity=26.4367816091954, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21356301, Length=180, Percent_Identity=32.7777777777778, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21357673, Length=192, Percent_Identity=25.5208333333333, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21358495, Length=215, Percent_Identity=25.5813953488372, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 28120; Mature: 28120

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLKDKIVVISGIGPGLGVKLAVEAAREGARGVVVAARTMEKLDDAEARIQALGVDCDVL
CCCCCCEEEEECCCCCCCCEEEEHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCEEE
KVKTDITDRAQCRQLATQAVERFGRIDALVNSAFVHGTFPEPVEEADLDGWRAVFDTNVF
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHCCCCCHHHHHCCCCH
GTMALTQEVVPHMKRQKRGAIVMINTQATRKPFAGEGGYAVSKGALAVAAKYLARELGVH
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHCCC
GIRANSIHMGWMWGVPTQTYFRQAAAEYGMTEEQIIAPIASNIALAKLPTDDDCARAALF
CEEECEEEEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEECCCCCHHHHHHHH
LASDYANAVTGATLDANGGDFMP
HHHHHHHHHCCCEEECCCCCCCC
>Mature Secondary Structure
MLLKDKIVVISGIGPGLGVKLAVEAAREGARGVVVAARTMEKLDDAEARIQALGVDCDVL
CCCCCCEEEEECCCCCCCCEEEEHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCEEE
KVKTDITDRAQCRQLATQAVERFGRIDALVNSAFVHGTFPEPVEEADLDGWRAVFDTNVF
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHCCCCCHHHHHCCCCH
GTMALTQEVVPHMKRQKRGAIVMINTQATRKPFAGEGGYAVSKGALAVAAKYLARELGVH
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHCCC
GIRANSIHMGWMWGVPTQTYFRQAAAEYGMTEEQIIAPIASNIALAKLPTDDDCARAALF
CEEECEEEEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEECCCCCHHHHHHHH
LASDYANAVTGATLDANGGDFMP
HHHHHHHHHCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]