Click here to switch to the map view.

The map label for this gene is mtaD [H]

Identifier: 78066946

GI number: 78066946

Start: 2561959

End: 2563347

Strand: Reverse

Name: mtaD [H]

Synonym: Bcep18194_A5477

Alternate gene names: 78066946

Gene position: 2563347-2561959 (Counterclockwise)

Preceding gene: 78066947

Following gene: 78066945

Centisome position: 69.39

GC content: 69.69

Gene sequence:

>1389_bases
ATGGATAGCCTCATGACCGACACCCTGTTGTTCGCAGACCATGCGTACCTGCCCGAAGGCTGGCGCCGTAACGTGCTGCT
GCGCTGGGACGCGGCCGGCACGCTGACCGGCGTGACGCCCGACACCGACGCACCCGCTGGCGTCGCGCGCGCGGCCGGGC
CCGTGATGCCCGGTATGCCGAACCTGCATTCGCACGCGTTCCAGCGCGCGATGGCGGGGCTCACCGAATACCGCGCGAAT
CCGTCCGACAGCTTCTGGAGCTGGCGCGACCTGATGTACCGCTTCGCGCTGAAGATCACGCCCGACGCGCTCGCGGCAAT
CGCGCGCTGGCTGTATGTCGAGATGCTCAAGTGCGGCTACACGTCGGTGTGCGAATTCCACTACGTGCACCACACGCAGG
ACGGCTCGCGCTATCCGCAGATCGCCGAGCTCGGCACGCGCGTGATCGACGCCGCACGCGCGGCCGGCATCGGCATCACG
ATGCTGCCGGTGTCGTACCAGTTCGCCGGCTTCGGCGACAAGCCGCCGCGCGACGACCAGCGCCGTTTCATCAATACGCC
CGACGGCCTGCTCGAGCTGCTCGACGCGATGCGTCGCGTGGCGCCGGAGCACGGCGGGCTGCGCTACGGCGTTGCGCCGC
ACTCGCTGCGGGCGGTATCCGAGAACGGGTTGCGCGTGCTGCTCGAAGGGTTGCCCGGCGATGCGCCCGTGCACATCCAT
ATCGCCGAGCAGACGGCCGAAGTCGACGACTGCGTGCGTGCCTACGGTGCGCGCCCCGTGCAATGGCTGCTCGATCGCTT
CGACGTCGATGCGCGCTGGTGCCTGGTGCACGCGACGCACGTCGACGCGGCCGAAACGGCAGCGCTCGCCAAGCGTCGCG
CGGTCGCCGGCCTGTGCCTGACGACCGAAGCAAATCTCGGCGACGGCGTGTTCCCGGCCGTCGACTATCTCGCGCAGGGT
GGTGTGATCGGTGTCGGCTCGGACAGCCACGCGTCGGTCGACTGGCGCTCGGAATTGCGCCTGCTCGAATACGGGCAGCG
GCTCGTGCATCGCGCGCGCAACGTGCTGGCGAGCGACACGCAGGCGCACGTCGCCGATCGCCTGTTCGACGCTTCGCTTG
CGGGCGGTGCACAGGCCAGCGGGCGGCATGTCGGTGCGCTGCGCGAAGGGTGCCGCGCCGACTGGCTCGTGCTCGATCCC
GATCATCCGGCGATCGCCGAACACGACAGCACGTCGTGGTTGTCGGGTATCGTGTTCGCGGAGCACGGCGAGACGCCGGT
GCTCGACGTCTACACGGGCGGCGAGCGCGTCGTGAGCGGCCGCCGTCATCGCGACGAAGCCGTCGCGTATGCCGACTACC
GCGCCGCGCTGGCGCAACTGCTGCGCTGA

Upstream 100 bases:

>100_bases
GCGTGGTCGGTCGGCTCGCTGGCGGAGCTCGCCTACTGGATCGGCCGGCCGCTGTGCGAGCAGGTCGTACGCGGCGGCAC
GACCGTGTTTCGCCGGATGA

Downstream 100 bases:

>100_bases
CGCGCGCAACCGGCGCACGCCGCAAGCGTGCGCCGGCAGACCTCCTACGGTGATGCGACATGACTGAACAACCGGCTGTA
TTCACGCTGAAGCAGGGCAC

Product: N-formimino-L-glutamate deiminase

Products: NA

Alternate protein names: MTA/SAH deaminase [H]

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MDSLMTDTLLFADHAYLPEGWRRNVLLRWDAAGTLTGVTPDTDAPAGVARAAGPVMPGMPNLHSHAFQRAMAGLTEYRAN
PSDSFWSWRDLMYRFALKITPDALAAIARWLYVEMLKCGYTSVCEFHYVHHTQDGSRYPQIAELGTRVIDAARAAGIGIT
MLPVSYQFAGFGDKPPRDDQRRFINTPDGLLELLDAMRRVAPEHGGLRYGVAPHSLRAVSENGLRVLLEGLPGDAPVHIH
IAEQTAEVDDCVRAYGARPVQWLLDRFDVDARWCLVHATHVDAAETAALAKRRAVAGLCLTTEANLGDGVFPAVDYLAQG
GVIGVGSDSHASVDWRSELRLLEYGQRLVHRARNVLASDTQAHVADRLFDASLAGGAQASGRHVGALREGCRADWLVLDP
DHPAIAEHDSTSWLSGIVFAEHGETPVLDVYTGGERVVSGRRHRDEAVAYADYRAALAQLLR

Sequences:

>Translated_462_residues
MDSLMTDTLLFADHAYLPEGWRRNVLLRWDAAGTLTGVTPDTDAPAGVARAAGPVMPGMPNLHSHAFQRAMAGLTEYRAN
PSDSFWSWRDLMYRFALKITPDALAAIARWLYVEMLKCGYTSVCEFHYVHHTQDGSRYPQIAELGTRVIDAARAAGIGIT
MLPVSYQFAGFGDKPPRDDQRRFINTPDGLLELLDAMRRVAPEHGGLRYGVAPHSLRAVSENGLRVLLEGLPGDAPVHIH
IAEQTAEVDDCVRAYGARPVQWLLDRFDVDARWCLVHATHVDAAETAALAKRRAVAGLCLTTEANLGDGVFPAVDYLAQG
GVIGVGSDSHASVDWRSELRLLEYGQRLVHRARNVLASDTQAHVADRLFDASLAGGAQASGRHVGALREGCRADWLVLDP
DHPAIAEHDSTSWLSGIVFAEHGETPVLDVYTGGERVVSGRRHRDEAVAYADYRAALAQLLR
>Mature_462_residues
MDSLMTDTLLFADHAYLPEGWRRNVLLRWDAAGTLTGVTPDTDAPAGVARAAGPVMPGMPNLHSHAFQRAMAGLTEYRAN
PSDSFWSWRDLMYRFALKITPDALAAIARWLYVEMLKCGYTSVCEFHYVHHTQDGSRYPQIAELGTRVIDAARAAGIGIT
MLPVSYQFAGFGDKPPRDDQRRFINTPDGLLELLDAMRRVAPEHGGLRYGVAPHSLRAVSENGLRVLLEGLPGDAPVHIH
IAEQTAEVDDCVRAYGARPVQWLLDRFDVDARWCLVHATHVDAAETAALAKRRAVAGLCLTTEANLGDGVFPAVDYLAQG
GVIGVGSDSHASVDWRSELRLLEYGQRLVHRARNVLASDTQAHVADRLFDASLAGGAQASGRHVGALREGCRADWLVLDP
DHPAIAEHDSTSWLSGIVFAEHGETPVLDVYTGGERVVSGRRHRDEAVAYADYRAALAQLLR

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17540282, Length=426, Percent_Identity=27.9342723004695, Blast_Score=172, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 50522; Mature: 50522

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSLMTDTLLFADHAYLPEGWRRNVLLRWDAAGTLTGVTPDTDAPAGVARAAGPVMPGMP
CCCHHHHHHHHHCCCCCCCCCCCCEEEEEECCCEEECCCCCCCCCCCHHHHCCCCCCCCC
NLHSHAFQRAMAGLTEYRANPSDSFWSWRDLMYRFALKITPDALAAIARWLYVEMLKCGY
CHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHCCC
TSVCEFHYVHHTQDGSRYPQIAELGTRVIDAARAAGIGITMLPVSYQFAGFGDKPPRDDQ
HHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCH
RRFINTPDGLLELLDAMRRVAPEHGGLRYGVAPHSLRAVSENGLRVLLEGLPGDAPVHIH
HHCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHCCCCEEEEECCCCCCCEEEE
IAEQTAEVDDCVRAYGARPVQWLLDRFDVDARWCLVHATHVDAAETAALAKRRAVAGLCL
ECCHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHEEEE
TTEANLGDGVFPAVDYLAQGGVIGVGSDSHASVDWRSELRLLEYGQRLVHRARNVLASDT
EECCCCCCCHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCH
QAHVADRLFDASLAGGAQASGRHVGALREGCRADWLVLDPDHPAIAEHDSTSWLSGIVFA
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHEEEE
EHGETPVLDVYTGGERVVSGRRHRDEAVAYADYRAALAQLLR
ECCCCCEEEEEECCHHHHCCCCCHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MDSLMTDTLLFADHAYLPEGWRRNVLLRWDAAGTLTGVTPDTDAPAGVARAAGPVMPGMP
CCCHHHHHHHHHCCCCCCCCCCCCEEEEEECCCEEECCCCCCCCCCCHHHHCCCCCCCCC
NLHSHAFQRAMAGLTEYRANPSDSFWSWRDLMYRFALKITPDALAAIARWLYVEMLKCGY
CHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHCCC
TSVCEFHYVHHTQDGSRYPQIAELGTRVIDAARAAGIGITMLPVSYQFAGFGDKPPRDDQ
HHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCH
RRFINTPDGLLELLDAMRRVAPEHGGLRYGVAPHSLRAVSENGLRVLLEGLPGDAPVHIH
HHCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHCCCCEEEEECCCCCCCEEEE
IAEQTAEVDDCVRAYGARPVQWLLDRFDVDARWCLVHATHVDAAETAALAKRRAVAGLCL
ECCHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHEEEE
TTEANLGDGVFPAVDYLAQGGVIGVGSDSHASVDWRSELRLLEYGQRLVHRARNVLASDT
EECCCCCCCHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCH
QAHVADRLFDASLAGGAQASGRHVGALREGCRADWLVLDPDHPAIAEHDSTSWLSGIVFA
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHEEEE
EHGETPVLDVYTGGERVVSGRRHRDEAVAYADYRAALAQLLR
ECCCCCEEEEEECCHHHHCCCCCHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA