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The map label for this gene is argE [H]

Identifier: 78066725

GI number: 78066725

Start: 2311243

End: 2312463

Strand: Direct

Name: argE [H]

Synonym: Bcep18194_A5256

Alternate gene names: 78066725

Gene position: 2311243-2312463 (Clockwise)

Preceding gene: 78066724

Following gene: 78066726

Centisome position: 62.57

GC content: 67.49

Gene sequence:

>1221_bases
ATGTCCACTCTCGACGCGACAGCGCCGTCCGCCGCAACCCAAGGCGACGCGTCGCTCGTCAGCCTGCCCTGGATCAAGCA
ACTGGTGTCGATGGACACGACGAGCCGCGTGCCGAACCTCGGCCTGATCGAAACGGTGCGCGACGCGCTCGCCGCGAAAG
GCATCGCATCGACGATCACGCACGATCCGCGCGAAGGCTGGGCGAACCTGTTTGCGACCGTGCCCGCGCACGACGGCTCG
ACGAACGGCGGCATCGTGCTGTCGGGACATACCGACGTCGTGCCGGTCGACGGCCAGCAATGGGACAGCAACCCGTTCGC
GCCGGAAATCCGCGACGGCCGCCTCTACGGCCGCGGCACCTGCGACATGAAGGGCTTCATCGGCACCGCGCTCGCGCTGC
TGCCCGAAATGCAGGCGACCAAGCTCGCGAAGCCGATCCATTTCGCGCTGTCCTACGACGAGGAAATCGGCTGCGCCGGT
GCGCCGCTGATGATCGCGGATCTGGTCAAGCGCGGCGTGCAACCGTCCGGCTGCATCGTCGGCGAGCCGACCAGCATGCG
GCCGATCATCGCGCACAAGGGCATCAACGCGTACCGCTGCTGCGTGCGCGGCCACGCGGCGCATTCGTCGCTGACGCCGA
AGGGGCTGAACGCGATCGAGTATGCGGCGCGCCTCATCTGCCACATCCGCGACATCGCCGACCGCTTCCGCGCCGAAGGC
CCGTTCGACGCACTCTACGACGTGCCGTTCACCACCGCGCAGACGAGCACGATCCAGGGCGGCAACGCGATCAACACGGT
GCCGGCCGAATGCCGGTTCGACTTCGAGTTCCGCAACCTGCCGACGCTCGATCCCGAGCAGATCTTCACGCGCATCGAAG
CGTATGCACGCGAAACACTGCTGCCGCAGATGCTGCGCGAGCATCCGAATGCCGCGATCGAGTTCTCGAAGATCGCCGCG
GCGCCCGGCCTCGACGCAACCGAACAGGCCGCAATCACGCAGCTCGTGCGCGCGCTGACGGCCGACCAGGACAAGCGCAA
GGTCGCCTACGGCACCGAGGCCGGCCTGTTCGAACGCGCGGGCATCCCGAGCGTCGTGTGCGGGCCCGGCAACATCGAGC
AGGCGCACAAGCCGAACGAATATGTCGAGCTCGCGCAGCTCGCCGGCTGCGAGCAGTTCCTGCGCAAGTTCATCCGCAGC
ATGTCGGTCGACGCGCACTGA

Upstream 100 bases:

>100_bases
TAGTGACGGGTGTGGCGTTGCTGCACCGCACTGCACCCGGCGCGGGCGGGCCGACGCGTTTTTGAGTATGATTTTCCCAT
TCATCAGACGGAGTTTTGCC

Downstream 100 bases:

>100_bases
CTGCCCCCCGCCACGCCGGCCCGCGTGTGCGGGCCGGCCCACTCCGCCACCCGCCACGTCATGTCGACTGAACAACAGGG
CACCGCCCATCCGACGATCG

Product: acetylornithine deacetylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MSTLDATAPSAATQGDASLVSLPWIKQLVSMDTTSRVPNLGLIETVRDALAAKGIASTITHDPREGWANLFATVPAHDGS
TNGGIVLSGHTDVVPVDGQQWDSNPFAPEIRDGRLYGRGTCDMKGFIGTALALLPEMQATKLAKPIHFALSYDEEIGCAG
APLMIADLVKRGVQPSGCIVGEPTSMRPIIAHKGINAYRCCVRGHAAHSSLTPKGLNAIEYAARLICHIRDIADRFRAEG
PFDALYDVPFTTAQTSTIQGGNAINTVPAECRFDFEFRNLPTLDPEQIFTRIEAYARETLLPQMLREHPNAAIEFSKIAA
APGLDATEQAAITQLVRALTADQDKRKVAYGTEAGLFERAGIPSVVCGPGNIEQAHKPNEYVELAQLAGCEQFLRKFIRS
MSVDAH

Sequences:

>Translated_406_residues
MSTLDATAPSAATQGDASLVSLPWIKQLVSMDTTSRVPNLGLIETVRDALAAKGIASTITHDPREGWANLFATVPAHDGS
TNGGIVLSGHTDVVPVDGQQWDSNPFAPEIRDGRLYGRGTCDMKGFIGTALALLPEMQATKLAKPIHFALSYDEEIGCAG
APLMIADLVKRGVQPSGCIVGEPTSMRPIIAHKGINAYRCCVRGHAAHSSLTPKGLNAIEYAARLICHIRDIADRFRAEG
PFDALYDVPFTTAQTSTIQGGNAINTVPAECRFDFEFRNLPTLDPEQIFTRIEAYARETLLPQMLREHPNAAIEFSKIAA
APGLDATEQAAITQLVRALTADQDKRKVAYGTEAGLFERAGIPSVVCGPGNIEQAHKPNEYVELAQLAGCEQFLRKFIRS
MSVDAH
>Mature_405_residues
STLDATAPSAATQGDASLVSLPWIKQLVSMDTTSRVPNLGLIETVRDALAAKGIASTITHDPREGWANLFATVPAHDGST
NGGIVLSGHTDVVPVDGQQWDSNPFAPEIRDGRLYGRGTCDMKGFIGTALALLPEMQATKLAKPIHFALSYDEEIGCAGA
PLMIADLVKRGVQPSGCIVGEPTSMRPIIAHKGINAYRCCVRGHAAHSSLTPKGLNAIEYAARLICHIRDIADRFRAEGP
FDALYDVPFTTAQTSTIQGGNAINTVPAECRFDFEFRNLPTLDPEQIFTRIEAYARETLLPQMLREHPNAAIEFSKIAAA
PGLDATEQAAITQLVRALTADQDKRKVAYGTEAGLFERAGIPSVVCGPGNIEQAHKPNEYVELAQLAGCEQFLRKFIRSM
SVDAH

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=363, Percent_Identity=31.9559228650138, Blast_Score=168, Evalue=7e-43,
Organism=Escherichia coli, GI1788816, Length=337, Percent_Identity=27.0029673590504, Blast_Score=85, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 43702; Mature: 43571

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLDATAPSAATQGDASLVSLPWIKQLVSMDTTSRVPNLGLIETVRDALAAKGIASTIT
CCCCCCCCCCCCCCCCCCEEEHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHC
HDPREGWANLFATVPAHDGSTNGGIVLSGHTDVVPVDGQQWDSNPFAPEIRDGRLYGRGT
CCHHHHHHHHEEEECCCCCCCCCCEEEECCCCEEECCCCCCCCCCCCCCCCCCEEECCCC
CDMKGFIGTALALLPEMQATKLAKPIHFALSYDEEIGCAGAPLMIADLVKRGVQPSGCIV
CCHHHHHHHHHHHHCCHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCEE
GEPTSMRPIIAHKGINAYRCCVRGHAAHSSLTPKGLNAIEYAARLICHIRDIADRFRAEG
CCCCCCCCHHHHCCCCHHHHHHHCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
PFDALYDVPFTTAQTSTIQGGNAINTVPAECRFDFEFRNLPTLDPEQIFTRIEAYARETL
CCHHHHCCCCCCCCCCEECCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHH
LPQMLREHPNAAIEFSKIAAAPGLDATEQAAITQLVRALTADQDKRKVAYGTEAGLFERA
HHHHHHHCCCCEEEHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHC
GIPSVVCGPGNIEQAHKPNEYVELAQLAGCEQFLRKFIRSMSVDAH
CCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
STLDATAPSAATQGDASLVSLPWIKQLVSMDTTSRVPNLGLIETVRDALAAKGIASTIT
CCCCCCCCCCCCCCCCCEEEHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHC
HDPREGWANLFATVPAHDGSTNGGIVLSGHTDVVPVDGQQWDSNPFAPEIRDGRLYGRGT
CCHHHHHHHHEEEECCCCCCCCCCEEEECCCCEEECCCCCCCCCCCCCCCCCCEEECCCC
CDMKGFIGTALALLPEMQATKLAKPIHFALSYDEEIGCAGAPLMIADLVKRGVQPSGCIV
CCHHHHHHHHHHHHCCHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCEE
GEPTSMRPIIAHKGINAYRCCVRGHAAHSSLTPKGLNAIEYAARLICHIRDIADRFRAEG
CCCCCCCCHHHHCCCCHHHHHHHCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
PFDALYDVPFTTAQTSTIQGGNAINTVPAECRFDFEFRNLPTLDPEQIFTRIEAYARETL
CCHHHHCCCCCCCCCCEECCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHH
LPQMLREHPNAAIEFSKIAAAPGLDATEQAAITQLVRALTADQDKRKVAYGTEAGLFERA
HHHHHHHCCCCEEEHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHC
GIPSVVCGPGNIEQAHKPNEYVELAQLAGCEQFLRKFIRSMSVDAH
CCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]