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The map label for this gene is exbB [H]

Identifier: 78066476

GI number: 78066476

Start: 2044131

End: 2045045

Strand: Reverse

Name: exbB [H]

Synonym: Bcep18194_A5007

Alternate gene names: 78066476

Gene position: 2045045-2044131 (Counterclockwise)

Preceding gene: 78066477

Following gene: 78066475

Centisome position: 55.36

GC content: 69.51

Gene sequence:

>915_bases
ATGACGAAGCGTTCACTGGCCGCGCTGGCGGCAAGCATCCTGATGTCCGTCGCCGCAATCGACGGGTTCGTTGCACCGCA
ACTCGCCCACGCGCAGGCAAGCGGCGCGGCCGGCACATCGGCACCGGCCGCGGCACCGTCGGCTGCACCGGCCCCGGTTC
CGGCCGCCGCCGAGCCGGCTCCGCCGCCCGCGCCGGCCACGACGGAGGCAGTCGAGAATCCGTACGGGCTTGGCGCGCTA
TGGAAGAACGGCGATTTCGTCGCCCGTTTCGTGCTGATCCTGCTGGTGATCATGTCGATGGGCAGCTGGTACATCATGAT
CACGAAGTTCCTGGAGCAGTTGCGCGCGAATCGCCGCGCGAAGCTGGCGGACGCGCAGCTCTGGACCGCGCCGTCGCTGG
CAGAAGGCGCCAGGCTGCTCGACGAGGCGTCGCCGTTCCGGTTCATCGCCGAAACGGCGATCGAGGCCGGCGAGCATCAT
GAAGACGCGCTGCTGGAGGCGGTGGACCGCAACACGTGGATCGACGTGTCGGTCGAGCGCTCGATCACGAACGTGTCGAA
CCGGATGCAGGACGGGCTCGCGTTCCTGGCCACGGTGGGCTCCACCGCGCCGTTCGTCGGGCTGTTCGGCACGGTCTGGG
GTATCTATCACGCGCTGACGGCCATCGGCATCGCCGGCCAGGCGTCGATCGACAAGGTCGCGGGCCCGGTGGGCGAGGCG
CTCATCATGACCGCGATCGGCCTCGCCGTCGCGGTGCCGGCGGTGCTCGGCTACAACTTCCTGGTCCGCCGCAACAAGTC
GGTGATGGAGCGGGTCCGCAACTTCGGCGCGCAACTCCATACCGTGCTGCTGGCCGGCAATCGGCGCCCGGTACGCGCGG
CGTCGTCGCCGGCAGCCGCGTCGCTCGCGAACTGA

Upstream 100 bases:

>100_bases
TCAATCTGAATTGATGCAGTGGGCGGCCCGGTGCGATCCGGGCCGGGAAAAACCATCCCGAACTGACGTATTAAGTTCAC
CGAAATAACTGGAGTGGGGT

Downstream 100 bases:

>100_bases
ACGGCTGACGGAGACGCGCGATGGCCATGAACGTCGGGCAGGACGATAGCGACGAGGTGATCGCCAACATCAACACGACG
CCGCTCGTCGACGTGATGCT

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MTKRSLAALAASILMSVAAIDGFVAPQLAHAQASGAAGTSAPAAAPSAAPAPVPAAAEPAPPPAPATTEAVENPYGLGAL
WKNGDFVARFVLILLVIMSMGSWYIMITKFLEQLRANRRAKLADAQLWTAPSLAEGARLLDEASPFRFIAETAIEAGEHH
EDALLEAVDRNTWIDVSVERSITNVSNRMQDGLAFLATVGSTAPFVGLFGTVWGIYHALTAIGIAGQASIDKVAGPVGEA
LIMTAIGLAVAVPAVLGYNFLVRRNKSVMERVRNFGAQLHTVLLAGNRRPVRAASSPAAASLAN

Sequences:

>Translated_304_residues
MTKRSLAALAASILMSVAAIDGFVAPQLAHAQASGAAGTSAPAAAPSAAPAPVPAAAEPAPPPAPATTEAVENPYGLGAL
WKNGDFVARFVLILLVIMSMGSWYIMITKFLEQLRANRRAKLADAQLWTAPSLAEGARLLDEASPFRFIAETAIEAGEHH
EDALLEAVDRNTWIDVSVERSITNVSNRMQDGLAFLATVGSTAPFVGLFGTVWGIYHALTAIGIAGQASIDKVAGPVGEA
LIMTAIGLAVAVPAVLGYNFLVRRNKSVMERVRNFGAQLHTVLLAGNRRPVRAASSPAAASLAN
>Mature_303_residues
TKRSLAALAASILMSVAAIDGFVAPQLAHAQASGAAGTSAPAAAPSAAPAPVPAAAEPAPPPAPATTEAVENPYGLGALW
KNGDFVARFVLILLVIMSMGSWYIMITKFLEQLRANRRAKLADAQLWTAPSLAEGARLLDEASPFRFIAETAIEAGEHHE
DALLEAVDRNTWIDVSVERSITNVSNRMQDGLAFLATVGSTAPFVGLFGTVWGIYHALTAIGIAGQASIDKVAGPVGEAL
IMTAIGLAVAVPAVLGYNFLVRRNKSVMERVRNFGAQLHTVLLAGNRRPVRAASSPAAASLAN

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1789381, Length=198, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1786958, Length=219, Percent_Identity=31.5068493150685, Blast_Score=92, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 31639; Mature: 31508

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKRSLAALAASILMSVAAIDGFVAPQLAHAQASGAAGTSAPAAAPSAAPAPVPAAAEPA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PPPAPATTEAVENPYGLGALWKNGDFVARFVLILLVIMSMGSWYIMITKFLEQLRANRRA
CCCCCCCHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHH
KLADAQLWTAPSLAEGARLLDEASPFRFIAETAIEAGEHHEDALLEAVDRNTWIDVSVER
HHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEHHH
SITNVSNRMQDGLAFLATVGSTAPFVGLFGTVWGIYHALTAIGIAGQASIDKVAGPVGEA
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
LIMTAIGLAVAVPAVLGYNFLVRRNKSVMERVRNFGAQLHTVLLAGNRRPVRAASSPAAA
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCHH
SLAN
CCCC
>Mature Secondary Structure 
TKRSLAALAASILMSVAAIDGFVAPQLAHAQASGAAGTSAPAAAPSAAPAPVPAAAEPA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PPPAPATTEAVENPYGLGALWKNGDFVARFVLILLVIMSMGSWYIMITKFLEQLRANRRA
CCCCCCCHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHH
KLADAQLWTAPSLAEGARLLDEASPFRFIAETAIEAGEHHEDALLEAVDRNTWIDVSVER
HHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEHHH
SITNVSNRMQDGLAFLATVGSTAPFVGLFGTVWGIYHALTAIGIAGQASIDKVAGPVGEA
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
LIMTAIGLAVAVPAVLGYNFLVRRNKSVMERVRNFGAQLHTVLLAGNRRPVRAASSPAAA
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCHH
SLAN
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9371459 [H]