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The map label for this gene is yrpG [H]

Identifier: 78066412

GI number: 78066412

Start: 1965451

End: 1966449

Strand: Reverse

Name: yrpG [H]

Synonym: Bcep18194_A4943

Alternate gene names: 78066412

Gene position: 1966449-1965451 (Counterclockwise)

Preceding gene: 78066413

Following gene: 78066411

Centisome position: 53.23

GC content: 59.96

Gene sequence:

>999_bases
ATGTCACTTGATTCCTACGTTACGCTCGGGCGTTCCGGGCTGCGTGTCAGCCCCTTCGGGCTCGGCGGCAATCTCATCGA
CACGGCCAAGGTGTATTCGAACGGACACTCCGAGAAAATCATCGGGGACTTTTTCGCTACACGGAAAGGCACGCGCAACC
AGAGTGTCATCGCAACGAAGCTTGCTGCCAATCTTCATCTTCGAAACCCGAACGGTGGCGGCACGGGGCACAAGGCGATC
ATCGACCAATGCGAGGCGTCCTTACGCCGCCTGCAGACCGATTACATCGATCTCTATCAGATGCATATCTGGGATCGGCA
CACTCCGATAGAAGAAACGATGCGTGCACTCGATGACTTGGTAACGGCCGGCAAGGTCCGCTATATCGGGATTTCCGATA
CGCCGGCCTGGAAAGTCGCTCAAGCCCAAACGACAGCGCTTTTCCGCGGCTGGGCGGCGCTGATCTCGATGCAGGTCGAG
TATTCGCTGCTGCAGCGGACCGTCGAGGGGGAGCTTGTGCCGATGGCGACGGACCTCGACATCGCCATCATGCCGTGGAG
TCCGTTAAAGAACGGATGGTTGTCGGGAAAATACACACGCGAAAGCGCCGCGAATTCTAAATCCGAACGTGCCGCGCTGG
TTGGCGTCCCGGGCGAGCGCGACTACAAGGTTATCGATGTACTGCTCTCGGTCGCCGCCGAGATGGAAGTGGCCCCCGCG
GCCGTCGCGCTGGCCTGGGTTCGCAGCCGCCCTGGCGTGACTTCGACACTGATCGGCACGCGGCGCGTTGATCACCTTCG
CGCCAATCTCGCCGCGCTCGAGATCAATCTGGCTGCGGAACATCGTGCGATGCTCGACGAGGTGTCCGAGCCCTCGCTGA
ACTTCCCGGCCGACTTGACGAGCAAGGCCGCACCGAATTTCATACTTGCCGGTGCGACAGTCAACGGCCAGACCTCACAA
CCGTTGCCGATGTTGGTGGACAGCGAAGTTCGCTATTAA

Upstream 100 bases:

>100_bases
CTCCTCACGCGCAGTGCCCCCAAAAGATCGTCGTAACCGACGATTGCCACGGCTCATCGGTCGCCTAGCATGCAAAGACC
TTGATCTGTGGAGCAATCCG

Downstream 100 bases:

>100_bases
AGCGGTCGTATCCGGCTGGGAATCGTGAAACGCGGGTGAAAACTGAAATCCGTTACAGTCCGACCGACCTGTGTACCTGA
GTGCTCCTTCACTCAGGTCG

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MSLDSYVTLGRSGLRVSPFGLGGNLIDTAKVYSNGHSEKIIGDFFATRKGTRNQSVIATKLAANLHLRNPNGGGTGHKAI
IDQCEASLRRLQTDYIDLYQMHIWDRHTPIEETMRALDDLVTAGKVRYIGISDTPAWKVAQAQTTALFRGWAALISMQVE
YSLLQRTVEGELVPMATDLDIAIMPWSPLKNGWLSGKYTRESAANSKSERAALVGVPGERDYKVIDVLLSVAAEMEVAPA
AVALAWVRSRPGVTSTLIGTRRVDHLRANLAALEINLAAEHRAMLDEVSEPSLNFPADLTSKAAPNFILAGATVNGQTSQ
PLPMLVDSEVRY

Sequences:

>Translated_332_residues
MSLDSYVTLGRSGLRVSPFGLGGNLIDTAKVYSNGHSEKIIGDFFATRKGTRNQSVIATKLAANLHLRNPNGGGTGHKAI
IDQCEASLRRLQTDYIDLYQMHIWDRHTPIEETMRALDDLVTAGKVRYIGISDTPAWKVAQAQTTALFRGWAALISMQVE
YSLLQRTVEGELVPMATDLDIAIMPWSPLKNGWLSGKYTRESAANSKSERAALVGVPGERDYKVIDVLLSVAAEMEVAPA
AVALAWVRSRPGVTSTLIGTRRVDHLRANLAALEINLAAEHRAMLDEVSEPSLNFPADLTSKAAPNFILAGATVNGQTSQ
PLPMLVDSEVRY
>Mature_331_residues
SLDSYVTLGRSGLRVSPFGLGGNLIDTAKVYSNGHSEKIIGDFFATRKGTRNQSVIATKLAANLHLRNPNGGGTGHKAII
DQCEASLRRLQTDYIDLYQMHIWDRHTPIEETMRALDDLVTAGKVRYIGISDTPAWKVAQAQTTALFRGWAALISMQVEY
SLLQRTVEGELVPMATDLDIAIMPWSPLKNGWLSGKYTRESAANSKSERAALVGVPGERDYKVIDVLLSVAAEMEVAPAA
VALAWVRSRPGVTSTLIGTRRVDHLRANLAALEINLAAEHRAMLDEVSEPSLNFPADLTSKAAPNFILAGATVNGQTSQP
LPMLVDSEVRY

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI4504825, Length=306, Percent_Identity=29.7385620915033, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI27436969, Length=303, Percent_Identity=29.7029702970297, Blast_Score=125, Evalue=4e-29,
Organism=Homo sapiens, GI27436962, Length=304, Percent_Identity=29.9342105263158, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI27436964, Length=303, Percent_Identity=30.03300330033, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI27436966, Length=300, Percent_Identity=30, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI27436971, Length=303, Percent_Identity=28.0528052805281, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI223718702, Length=304, Percent_Identity=29.9342105263158, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI41152114, Length=299, Percent_Identity=29.7658862876254, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI41327764, Length=302, Percent_Identity=28.8079470198675, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI223718708, Length=128, Percent_Identity=39.0625, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI87081735, Length=275, Percent_Identity=38.5454545454545, Blast_Score=171, Evalue=6e-44,
Organism=Escherichia coli, GI1788070, Length=285, Percent_Identity=34.0350877192982, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1789199, Length=307, Percent_Identity=29.9674267100977, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1788081, Length=268, Percent_Identity=31.7164179104478, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1789375, Length=295, Percent_Identity=28.8135593220339, Blast_Score=94, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6323998, Length=287, Percent_Identity=35.8885017421603, Blast_Score=168, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6319958, Length=287, Percent_Identity=34.4947735191638, Blast_Score=160, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6325169, Length=342, Percent_Identity=32.1637426900585, Blast_Score=140, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6322615, Length=263, Percent_Identity=33.0798479087452, Blast_Score=140, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6319951, Length=287, Percent_Identity=31.3588850174216, Blast_Score=138, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6321052, Length=110, Percent_Identity=40, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24640980, Length=319, Percent_Identity=24.7648902821317, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI45549126, Length=319, Percent_Identity=24.7648902821317, Blast_Score=74, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36139; Mature: 36007

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLDSYVTLGRSGLRVSPFGLGGNLIDTAKVYSNGHSEKIIGDFFATRKGTRNQSVIATK
CCCCCEEEECCCCCEECCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHEEEE
LAANLHLRNPNGGGTGHKAIIDQCEASLRRLQTDYIDLYQMHIWDRHTPIEETMRALDDL
EEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
VTAGKVRYIGISDTPAWKVAQAQTTALFRGWAALISMQVEYSLLQRTVEGELVPMATDLD
HHCCCEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
IAIMPWSPLKNGWLSGKYTRESAANSKSERAALVGVPGERDYKVIDVLLSVAAEMEVAPA
EEEECCCCCCCCCCCCCCCHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
AVALAWVRSRPGVTSTLIGTRRVDHLRANLAALEINLAAEHRAMLDEVSEPSLNFPADLT
HHHHHHHHCCCCCHHHHHHHHHHHHHHHCEEEEEEEEHHHHHHHHHHCCCCCCCCCCCCH
SKAAPNFILAGATVNGQTSQPLPMLVDSEVRY
HCCCCCEEEEEEEECCCCCCCCCEECCCCCCC
>Mature Secondary Structure 
SLDSYVTLGRSGLRVSPFGLGGNLIDTAKVYSNGHSEKIIGDFFATRKGTRNQSVIATK
CCCCEEEECCCCCEECCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHEEEE
LAANLHLRNPNGGGTGHKAIIDQCEASLRRLQTDYIDLYQMHIWDRHTPIEETMRALDDL
EEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
VTAGKVRYIGISDTPAWKVAQAQTTALFRGWAALISMQVEYSLLQRTVEGELVPMATDLD
HHCCCEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
IAIMPWSPLKNGWLSGKYTRESAANSKSERAALVGVPGERDYKVIDVLLSVAAEMEVAPA
EEEECCCCCCCCCCCCCCCHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
AVALAWVRSRPGVTSTLIGTRRVDHLRANLAALEINLAAEHRAMLDEVSEPSLNFPADLT
HHHHHHHHCCCCCHHHHHHHHHHHHHHHCEEEEEEEEHHHHHHHHHHCCCCCCCCCCCCH
SKAAPNFILAGATVNGQTSQPLPMLVDSEVRY
HCCCCCEEEEEEEECCCCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9308178; 9384377 [H]