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The map label for this gene is yfjP [H]

Identifier: 78066400

GI number: 78066400

Start: 1948762

End: 1949406

Strand: Direct

Name: yfjP [H]

Synonym: Bcep18194_A4930

Alternate gene names: 78066400

Gene position: 1948762-1949406 (Clockwise)

Preceding gene: 78066399

Following gene: 78066401

Centisome position: 52.75

GC content: 61.55

Gene sequence:

>645_bases
TTGACCGACACCATCTCAGCCGACCTGTCTCCGCGCGCCTATCGGAAAGCTGCTCAGTTCCTGTCGGACTTCGACAAGGA
CTGGGCTAGTCATATCGCCAAAATCGGCCCGTGCAGGCATGAGGCCAAGCCCGCCCGCGAGCCATACGAGGCGCTGGTTC
GGGCGATAGCCTATCAGCAACTACACGCCAAAGCTGGCGATGCGATTCTTGGGCGGTTGCTTGCGCTCTATCCCGGTACG
GACTTTCCCGCTCCCGAGCAACTGCTGTCGACCGATCCGGCGCTGCAACGTGCCTGTGGCTTCTCGGCTACCAAGCTGGC
GACGATTCGCAGTATCGCCCAGGCTACCGTGGACGAAATCGTACCGAGTCTAGACGAGGCACGGCGCCTTCCCGATGCGA
CGCTGATCGAGCGCCTCATTACGCTACGCGGTGTCGGGCGCTGGACGGTAGAGATGTTCCTGATCTATTCACTTGAGCGC
TCGGACATTCTGCCAGTTGACGACTTCGGTGTTCGCGAGGGTTACGGGCGTCTGAAGGGGTTGGAGAAGGCACCGACACC
GCGCCAGATGCGTGACATCGGTGAAGCCTGGAGCCCATACCGGACTGTCGCCGCGTGGTACTTGTGGCGACTGCCCAGCC
GATGA

Upstream 100 bases:

>100_bases
CATGGGGCCTACATCGTAAGCGCTGGTTGCTGGAGCATGAAGGGGCAATCCCGCCGCAACGCACCGAACCCCAAACTGCC
ACGCTGCCAGGATTTTGATT

Downstream 100 bases:

>100_bases
ATTTTGATAGCAAGAATCGGAGTTCTTGCGAATGAAGTCCGGCCTATCCTGATTCCGTGATTGATGCTTCCAGGACTGCC
ACAATGAATACGATCACTGT

Product: DNA-3-methyladenine glycosylase II

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 213

Protein sequence:

>214_residues
MTDTISADLSPRAYRKAAQFLSDFDKDWASHIAKIGPCRHEAKPAREPYEALVRAIAYQQLHAKAGDAILGRLLALYPGT
DFPAPEQLLSTDPALQRACGFSATKLATIRSIAQATVDEIVPSLDEARRLPDATLIERLITLRGVGRWTVEMFLIYSLER
SDILPVDDFGVREGYGRLKGLEKAPTPRQMRDIGEAWSPYRTVAAWYLWRLPSR

Sequences:

>Translated_214_residues
MTDTISADLSPRAYRKAAQFLSDFDKDWASHIAKIGPCRHEAKPAREPYEALVRAIAYQQLHAKAGDAILGRLLALYPGT
DFPAPEQLLSTDPALQRACGFSATKLATIRSIAQATVDEIVPSLDEARRLPDATLIERLITLRGVGRWTVEMFLIYSLER
SDILPVDDFGVREGYGRLKGLEKAPTPRQMRDIGEAWSPYRTVAAWYLWRLPSR
>Mature_213_residues
TDTISADLSPRAYRKAAQFLSDFDKDWASHIAKIGPCRHEAKPAREPYEALVRAIAYQQLHAKAGDAILGRLLALYPGTD
FPAPEQLLSTDPALQRACGFSATKLATIRSIAQATVDEIVPSLDEARRLPDATLIERLITLRGVGRWTVEMFLIYSLERS
DILPVDDFGVREGYGRLKGLEKAPTPRQMRDIGEAWSPYRTVAAWYLWRLPSR

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, 3-methylguanine, 7-methylguanine, O2- methylthymine, and O2-methylcytosine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG0122

COG function: function code L; 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alkylbase DNA glycosidase alkA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011257
- InterPro:   IPR003265
- InterPro:   IPR003583
- InterPro:   IPR023170 [H]

Pfam domain/function: PF00730 HhH-GPD [H]

EC number: =3.2.2.21 [H]

Molecular weight: Translated: 23997; Mature: 23866

Theoretical pI: Translated: 8.65; Mature: 8.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTISADLSPRAYRKAAQFLSDFDKDWASHIAKIGPCRHEAKPAREPYEALVRAIAYQQ
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHHHH
LHAKAGDAILGRLLALYPGTDFPAPEQLLSTDPALQRACGFSATKLATIRSIAQATVDEI
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHH
VPSLDEARRLPDATLIERLITLRGVGRWTVEMFLIYSLERSDILPVDDFGVREGYGRLKG
HCCHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCC
LEKAPTPRQMRDIGEAWSPYRTVAAWYLWRLPSR
CCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TDTISADLSPRAYRKAAQFLSDFDKDWASHIAKIGPCRHEAKPAREPYEALVRAIAYQQ
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHHHH
LHAKAGDAILGRLLALYPGTDFPAPEQLLSTDPALQRACGFSATKLATIRSIAQATVDEI
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHH
VPSLDEARRLPDATLIERLITLRGVGRWTVEMFLIYSLERSDILPVDDFGVREGYGRLKG
HCCHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCC
LEKAPTPRQMRDIGEAWSPYRTVAAWYLWRLPSR
CCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]