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The map label for this gene is yafC [H]

Identifier: 78066337

GI number: 78066337

Start: 1885700

End: 1886626

Strand: Direct

Name: yafC [H]

Synonym: Bcep18194_A4867

Alternate gene names: 78066337

Gene position: 1885700-1886626 (Clockwise)

Preceding gene: 78066334

Following gene: 78066338

Centisome position: 51.05

GC content: 69.04

Gene sequence:

>927_bases
ATGGATCGAATCGATGCGATGAAGGTGTTCGTCGCCACGCTGGACGAGGGCAGCCTCGCGGGCGCGGGCCGGAAGCTCGG
CCGGTCGCCGGCGGCCGTCAGCCGAGCGATCGCGTTCCTTGAAGAACACACGGGCACCGCGCTGCTGTACCGCACGACCC
GGACGATCCGGCTGAGCGAAGCCGGCGAACGCTATGCGGCCGCGTGCCGGCGCATCCTGTCCGATCTCGAGGAAGCCGAC
ATGCTGGTCGCCGACGAGCGGTCGGCGCCGCGCGGCCTGTTGACGGTCACGGCACCGGTCGCCGCCGGCGAAGACGTGCT
GCGCGCGCTCCTCGACGAATTCATCGAACGCCATCCGGCCGTGTCGATCCGCCTGCAGTTGCTCGACCGCCCCGTCAGCC
TGATCGACGAAGGAATGGACGTCGCGCTGCGCATTGCGCACCTGACCGATTCGACGCTCGTCGCGATTCCGGTCGGCGCG
GTGCGGCGGGTCGTCGTGGCGTCGCCCGATTACCTGGCGAAGCATCCGGCGATCGAGACGCCGGCCGATCTCGCGCAGCA
CCGGATCATCTCGATGACGCATTTCGGCCTCGATTCGTGGAGCTTTCCGCCGTCCGCGCCATCGGCACTGCCGCAGGTCG
TCCAGTTCGCGCCGCGCTTCATCATCAACACGATCCGCGGCGCGGTCGCATCGGCCGTCGCAGGCCACGGCGTCACGCGG
CTCTTTTCCTATCACGTCGCAGAACCGGTGCGGAGCGGCGCGCTGCGGATCGTGCTGCGCGACAGCGAACACGCGCCGCT
GCCGATCCATCTCGTCACGCCTTACGGACGCCTTTCGGTGCCGAAGGTGCGCGCCTTCGTCGATTTCGCTGCACCGCGCC
TGCGCGAGCACTTCGCGCAGCTGGCGGCCGTGACCGACGGCGATTGA

Upstream 100 bases:

>100_bases
GGCGCAACGTCCTCGGCCAGGCGCCGCACCCGCGTGCGGTAGACTGCACGCTCGCTTGCCCACCGCCCACTACACGACCG
CTCGCGCCCGCTGACACGCC

Downstream 100 bases:

>100_bases
ACCGCGATGCGGAAGAATGGCTTTCGCGTGACGGGGATTCACTCGGCAATCGCCTCAATCTAGACTTCCTTCAACCAACG
GACGCACGTGTCGCCCGTTC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MDRIDAMKVFVATLDEGSLAGAGRKLGRSPAAVSRAIAFLEEHTGTALLYRTTRTIRLSEAGERYAAACRRILSDLEEAD
MLVADERSAPRGLLTVTAPVAAGEDVLRALLDEFIERHPAVSIRLQLLDRPVSLIDEGMDVALRIAHLTDSTLVAIPVGA
VRRVVVASPDYLAKHPAIETPADLAQHRIISMTHFGLDSWSFPPSAPSALPQVVQFAPRFIINTIRGAVASAVAGHGVTR
LFSYHVAEPVRSGALRIVLRDSEHAPLPIHLVTPYGRLSVPKVRAFVDFAAPRLREHFAQLAAVTDGD

Sequences:

>Translated_308_residues
MDRIDAMKVFVATLDEGSLAGAGRKLGRSPAAVSRAIAFLEEHTGTALLYRTTRTIRLSEAGERYAAACRRILSDLEEAD
MLVADERSAPRGLLTVTAPVAAGEDVLRALLDEFIERHPAVSIRLQLLDRPVSLIDEGMDVALRIAHLTDSTLVAIPVGA
VRRVVVASPDYLAKHPAIETPADLAQHRIISMTHFGLDSWSFPPSAPSALPQVVQFAPRFIINTIRGAVASAVAGHGVTR
LFSYHVAEPVRSGALRIVLRDSEHAPLPIHLVTPYGRLSVPKVRAFVDFAAPRLREHFAQLAAVTDGD
>Mature_308_residues
MDRIDAMKVFVATLDEGSLAGAGRKLGRSPAAVSRAIAFLEEHTGTALLYRTTRTIRLSEAGERYAAACRRILSDLEEAD
MLVADERSAPRGLLTVTAPVAAGEDVLRALLDEFIERHPAVSIRLQLLDRPVSLIDEGMDVALRIAHLTDSTLVAIPVGA
VRRVVVASPDYLAKHPAIETPADLAQHRIISMTHFGLDSWSFPPSAPSALPQVVQFAPRFIINTIRGAVASAVAGHGVTR
LFSYHVAEPVRSGALRIVLRDSEHAPLPIHLVTPYGRLSVPKVRAFVDFAAPRLREHFAQLAAVTDGD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=295, Percent_Identity=31.864406779661, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI145693193, Length=299, Percent_Identity=29.7658862876254, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI1789639, Length=307, Percent_Identity=28.3387622149837, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI87081978, Length=301, Percent_Identity=27.5747508305648, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1787128, Length=289, Percent_Identity=25.2595155709343, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1789440, Length=258, Percent_Identity=24.4186046511628, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787589, Length=292, Percent_Identity=25.6849315068493, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1789173, Length=187, Percent_Identity=30.4812834224599, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1786713, Length=195, Percent_Identity=29.2307692307692, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787601, Length=135, Percent_Identity=27.4074074074074, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33300; Mature: 33300

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRIDAMKVFVATLDEGSLAGAGRKLGRSPAAVSRAIAFLEEHTGTALLYRTTRTIRLSE
CCCHHHHHHHHHCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCEEEEEEEEEEEECC
AGERYAAACRRILSDLEEADMLVADERSAPRGLLTVTAPVAAGEDVLRALLDEFIERHPA
CCHHHHHHHHHHHHHHHHHHEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCC
VSIRLQLLDRPVSLIDEGMDVALRIAHLTDSTLVAIPVGAVRRVVVASPDYLAKHPAIET
CEEEHHHHHCCHHHHHCCCHHEEEEEECCCCEEEEECHHHHHEEEEECCCHHHCCCCCCC
PADLAQHRIISMTHFGLDSWSFPPSAPSALPQVVQFAPRFIINTIRGAVASAVAGHGVTR
HHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
LFSYHVAEPVRSGALRIVLRDSEHAPLPIHLVTPYGRLSVPKVRAFVDFAAPRLREHFAQ
HHHHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
LAAVTDGD
HHHCCCCC
>Mature Secondary Structure
MDRIDAMKVFVATLDEGSLAGAGRKLGRSPAAVSRAIAFLEEHTGTALLYRTTRTIRLSE
CCCHHHHHHHHHCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCEEEEEEEEEEEECC
AGERYAAACRRILSDLEEADMLVADERSAPRGLLTVTAPVAAGEDVLRALLDEFIERHPA
CCHHHHHHHHHHHHHHHHHHEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCC
VSIRLQLLDRPVSLIDEGMDVALRIAHLTDSTLVAIPVGAVRRVVVASPDYLAKHPAIET
CEEEHHHHHCCHHHHHCCCHHEEEEEECCCCEEEEECHHHHHEEEEECCCHHHCCCCCCC
PADLAQHRIISMTHFGLDSWSFPPSAPSALPQVVQFAPRFIINTIRGAVASAVAGHGVTR
HHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
LFSYHVAEPVRSGALRIVLRDSEHAPLPIHLVTPYGRLSVPKVRAFVDFAAPRLREHFAQ
HHHHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
LAAVTDGD
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]