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The map label for this gene is exuT [H]

Identifier: 78066313

GI number: 78066313

Start: 1861011

End: 1862339

Strand: Direct

Name: exuT [H]

Synonym: Bcep18194_A4843

Alternate gene names: 78066313

Gene position: 1861011-1862339 (Clockwise)

Preceding gene: 78066312

Following gene: 78066314

Centisome position: 50.38

GC content: 71.26

Gene sequence:

>1329_bases
ATGCTGATCCATCATGTCGAGCCGTCGATGCAGGACGTCGCCGCCGCCGGCCGGCGCGCGCCCGCGTATGCGTGGCTCGT
GTTCGGGCTGACCGTCGGCATGCTGCTGTCGGACTACATGTCGCGGCAGGTGCTCAACGCCGTGTTCCCGCTGCTCAAGC
ACGCGTGGGCGCTGTCGGACACGCAGCTCGGTTCGCTGTCCGGCGTCGTCGCGCTGCTGGTCGGGCTGCTGACGTTTCCG
CTGTCGGTGCTCGCCGACCGCTTCGGGCGCGTGCGCAGCATCGTGCTGATGGCCGCGTTGTGGAGCGTCGCGACGCTCGG
CTGCGCGCTGTCGACCAACTACACGGAGATGCTCGTCGCGCGCGGCCTCGTCGGGCTCGGCGAAGCCGCGTACGGCAGCG
TCGGCGTCGCGCTGATCCTCAGCATCTTTCCGGCACGGCTGCGCGCGACGCTGACCGGCGCGTTCATGGCCGGCGGCGCG
TTCGGCTCGGTGTTCGGGATGGCGCTCGGCGGACTGGTCGGCGCGCATCTCGGCTGGCGCTGGTCGTTCGGCGTGATGGC
CGCGCTCGGCATCGTGCTGCTCGTCGCGTATCGCTGCGTCGTGACCGAACGTCGGCTCGCCGCGTATCGCATCGAACCGT
GCCGGCGCGACGCCAATACGCCGCGCGACCTGCGCGGCAACGTGCGCGCGCTGATGTCGGGGCTGTTCGCATCGCGTTCG
GTGATCTGCGCGTATCTCGGCAGCGGGCTGCACCTGTTCGTGCCGGGCGCGCTGTTCGCGTGGCTGCCGAGCTACCTGAA
CCGTTACTACGCGATGGCGCCCGACCGCGCGGCCGTGCTCGCAGCCGGCTTCGTGTTGCTCGCGGGCGTCGGGATGGTCG
GTTGCGGGATCGTCACCGACCGCGTCGGCAAGACCGACGGCAAGCGCAAGTGGCTGACCGCGATCGCGTATTGCGTCCTC
ACGGGCGTCTGCCTCGCGATCGCGTTCCGGCTGCCGCCCGGGCCGCTGCAGCTCGCGCTGATCTGCGCGGGGATGCTGGT
CGGCGCGGGCGCGTCCGGTGCGTCGGGCGCGATGGTCGCGAACCTGACGCCGGCCGCGATCCACGCATCGGCGTTCGCCA
CGCTCACGCTCGCCAACAACCTGCTCGGCATGGCGCCGGGCCCGCTGCTGACGGGGTGGGTTGCCGATCGCGCCGGGCTC
GTCGGCGCACTGCAATGGATTCCCGTCGTGCCGCTCATGGCCGCCGTGCTGTTCGCGATCGGACGCGCGAGCTATGTGGC
CGACCTCGCGCGCGTCGAACGCGAACGGCGCGCGTCCCAACTTTCCTGA

Upstream 100 bases:

>100_bases
CCCATCCCCGCGCACGGCGCGGGGGCTGACTCCGGACCACGGAGCGGGGCCACGCAAGCCGCGCCGGAGCACGACCGCTC
TGGTGCCGGAGGAGACACGC

Downstream 100 bases:

>100_bases
ACGTTTCGGAGACTGCATGACCCTGACGACCGCCCCCACCATCCTGATCGTGCCCGGCTTGCGCGATCACGTCGAAGACC
ACTGGCAAACGCACCTCGAA

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MLIHHVEPSMQDVAAAGRRAPAYAWLVFGLTVGMLLSDYMSRQVLNAVFPLLKHAWALSDTQLGSLSGVVALLVGLLTFP
LSVLADRFGRVRSIVLMAALWSVATLGCALSTNYTEMLVARGLVGLGEAAYGSVGVALILSIFPARLRATLTGAFMAGGA
FGSVFGMALGGLVGAHLGWRWSFGVMAALGIVLLVAYRCVVTERRLAAYRIEPCRRDANTPRDLRGNVRALMSGLFASRS
VICAYLGSGLHLFVPGALFAWLPSYLNRYYAMAPDRAAVLAAGFVLLAGVGMVGCGIVTDRVGKTDGKRKWLTAIAYCVL
TGVCLAIAFRLPPGPLQLALICAGMLVGAGASGASGAMVANLTPAAIHASAFATLTLANNLLGMAPGPLLTGWVADRAGL
VGALQWIPVVPLMAAVLFAIGRASYVADLARVERERRASQLS

Sequences:

>Translated_442_residues
MLIHHVEPSMQDVAAAGRRAPAYAWLVFGLTVGMLLSDYMSRQVLNAVFPLLKHAWALSDTQLGSLSGVVALLVGLLTFP
LSVLADRFGRVRSIVLMAALWSVATLGCALSTNYTEMLVARGLVGLGEAAYGSVGVALILSIFPARLRATLTGAFMAGGA
FGSVFGMALGGLVGAHLGWRWSFGVMAALGIVLLVAYRCVVTERRLAAYRIEPCRRDANTPRDLRGNVRALMSGLFASRS
VICAYLGSGLHLFVPGALFAWLPSYLNRYYAMAPDRAAVLAAGFVLLAGVGMVGCGIVTDRVGKTDGKRKWLTAIAYCVL
TGVCLAIAFRLPPGPLQLALICAGMLVGAGASGASGAMVANLTPAAIHASAFATLTLANNLLGMAPGPLLTGWVADRAGL
VGALQWIPVVPLMAAVLFAIGRASYVADLARVERERRASQLS
>Mature_442_residues
MLIHHVEPSMQDVAAAGRRAPAYAWLVFGLTVGMLLSDYMSRQVLNAVFPLLKHAWALSDTQLGSLSGVVALLVGLLTFP
LSVLADRFGRVRSIVLMAALWSVATLGCALSTNYTEMLVARGLVGLGEAAYGSVGVALILSIFPARLRATLTGAFMAGGA
FGSVFGMALGGLVGAHLGWRWSFGVMAALGIVLLVAYRCVVTERRLAAYRIEPCRRDANTPRDLRGNVRALMSGLFASRS
VICAYLGSGLHLFVPGALFAWLPSYLNRYYAMAPDRAAVLAAGFVLLAGVGMVGCGIVTDRVGKTDGKRKWLTAIAYCVL
TGVCLAIAFRLPPGPLQLALICAGMLVGAGASGASGAMVANLTPAAIHASAFATLTLANNLLGMAPGPLLTGWVADRAGL
VGALQWIPVVPLMAAVLFAIGRASYVADLARVERERRASQLS

Specific function: Aldohexuronate transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI215490096, Length=472, Percent_Identity=24.364406779661, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI14042968, Length=472, Percent_Identity=24.364406779661, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI185136021, Length=440, Percent_Identity=22.7272727272727, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI215490100, Length=436, Percent_Identity=24.5412844036697, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI87082320, Length=414, Percent_Identity=24.8792270531401, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI2367379, Length=297, Percent_Identity=26.2626262626263, Blast_Score=76, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17539092, Length=449, Percent_Identity=24.2761692650334, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193209775, Length=455, Percent_Identity=22.6373626373626, Blast_Score=66, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17557872, Length=437, Percent_Identity=24.0274599542334, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI17864456, Length=269, Percent_Identity=23.7918215613383, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24654039, Length=269, Percent_Identity=23.7918215613383, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24654044, Length=259, Percent_Identity=23.9382239382239, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24654037, Length=259, Percent_Identity=23.9382239382239, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24654041, Length=259, Percent_Identity=23.9382239382239, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46260; Mature: 46260

Theoretical pI: Translated: 10.26; Mature: 10.26

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]