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The map label for this gene is cobL [H]

Identifier: 78066296

GI number: 78066296

Start: 1842616

End: 1843869

Strand: Direct

Name: cobL [H]

Synonym: Bcep18194_A4826

Alternate gene names: 78066296

Gene position: 1842616-1843869 (Clockwise)

Preceding gene: 78066295

Following gene: 78066297

Centisome position: 49.88

GC content: 74.16

Gene sequence:

>1254_bases
ATGACGGCGTGGCTGACAGTAGTAGGCATCGGCGACGACGGTTACGCGGGGCTCGGACGCAGCGCGCGGCGCGCGCTGCT
CGACGCGACGCTCGTCGTCGGCGCGAAGCGGCATCTCGACATGCTGCCCGCGCGGCTGCCGGCCGCGCGCGAAACCTGGC
CGTCGCCGTTCGATCTCGCGGGCGTGCTGGCCCGACGCGCATCGCCCGTCTGCGTGCTCGCCAGTGGCGACCCGATGCTG
TTCGGCGTCGGCGCCACGCTCGCGCGCCAGCTTTCCCCCGACGAATGGCGCGTGCTGCCCGCACCGTCGTCGCTGTCGCT
GGCAGCCGCGCGCCTCGGCTGGGCGCTGCAGGATGTCGGCGCGGTCTCGCTCGTCGGCCGTCCGCTTGCGACGCTCGCGC
GTCACCTGCTGCCCGGCCGCCGCCTGTTCGTGCTGAGCGCCGACGGCCGCACGCCGGCCGCCGTCGCGGCCGAACTCGTC
GCACGCGGCTTCGGGCCGACGCGCATCAGCGTGTTCGAACATCTCGGCGGCCCGCTCGAGCGGCGTCTCGACGGGCTCGC
ACAGGGCTGGCGCATCGACGAAACGGCCGCGCTCAATCTGGTGGCGCTCGACTGCCAGGCCTGCCCCGACGCGCCGCGCC
GCGCGCTCACGCCCGGCCTGCCCGACGACGCGTACCGTCACGACGGCCAGCTCACCAAGCGCGACCTGCGCGCCATGACG
CTCGGCCGCCTCGCGCCCGTGCCCGGCGAGCTGCTGTGGGACGTCGGCGCCGGCAGCGGCTCGATCGGCATCGAGTGGAT
GCGCGCGCATCCGTCATGCCAGGCAATCGCGATCGAAGCGCATGCGGAGCGGCAACGCTTCATCGAACACAACCGTGATG
CGCTCGGCGTGCCGGGCCTGCAACTCGTCGCGGGCCGCGCCCCCGATGCGCTCGCGGGGCTCGCCGCGCCCGACGCGATC
TTCATCGGCGGCGGGGCGACCGCACCCGGTGTGCTCGACGCGTGCTGGGCAGCGCTGAAACCGGGCGGCCGGCTGGTCGC
GAACGCGGTCACGCTGCAGGGCGAGATGGCGCTCGCCGCGTGGCGCGATGCGCATGGCGGCACACTTACGCGTGTGTCGC
TCGCACACGCCGAGCCGCTCGGCCGTTTCGACACGTGGCGGCAACCGTTGCCGGTCACGCTGTACGACGTGCGCAAGCCC
GACACCGCCGACACGCCCGCACCGTCGACCGCGACGAACGCAACGGACGCGTGA

Upstream 100 bases:

>100_bases
CGCACCGGTCACGCTCGGCACATCAACGAATCAACGCGCGGCGGCCCAGCCGCCGCGCATCGCAACAAACGGTAGGGAAT
CGAACGATGGGGAAGGGTGC

Downstream 100 bases:

>100_bases
TGCGCGACGAGACCCCCGAACAGCCCGCGCCGCTACGCTTCGGCTATACGACCGGCAGCTGCGCGACCGCGACGTCGCTC
GCCGCCGCACGGCTGCTGCT

Product: precorrin-6Y C5,15-methyltransferase (decarboxylating)

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MTAWLTVVGIGDDGYAGLGRSARRALLDATLVVGAKRHLDMLPARLPAARETWPSPFDLAGVLARRASPVCVLASGDPML
FGVGATLARQLSPDEWRVLPAPSSLSLAAARLGWALQDVGAVSLVGRPLATLARHLLPGRRLFVLSADGRTPAAVAAELV
ARGFGPTRISVFEHLGGPLERRLDGLAQGWRIDETAALNLVALDCQACPDAPRRALTPGLPDDAYRHDGQLTKRDLRAMT
LGRLAPVPGELLWDVGAGSGSIGIEWMRAHPSCQAIAIEAHAERQRFIEHNRDALGVPGLQLVAGRAPDALAGLAAPDAI
FIGGGATAPGVLDACWAALKPGGRLVANAVTLQGEMALAAWRDAHGGTLTRVSLAHAEPLGRFDTWRQPLPVTLYDVRKP
DTADTPAPSTATNATDA

Sequences:

>Translated_417_residues
MTAWLTVVGIGDDGYAGLGRSARRALLDATLVVGAKRHLDMLPARLPAARETWPSPFDLAGVLARRASPVCVLASGDPML
FGVGATLARQLSPDEWRVLPAPSSLSLAAARLGWALQDVGAVSLVGRPLATLARHLLPGRRLFVLSADGRTPAAVAAELV
ARGFGPTRISVFEHLGGPLERRLDGLAQGWRIDETAALNLVALDCQACPDAPRRALTPGLPDDAYRHDGQLTKRDLRAMT
LGRLAPVPGELLWDVGAGSGSIGIEWMRAHPSCQAIAIEAHAERQRFIEHNRDALGVPGLQLVAGRAPDALAGLAAPDAI
FIGGGATAPGVLDACWAALKPGGRLVANAVTLQGEMALAAWRDAHGGTLTRVSLAHAEPLGRFDTWRQPLPVTLYDVRKP
DTADTPAPSTATNATDA
>Mature_416_residues
TAWLTVVGIGDDGYAGLGRSARRALLDATLVVGAKRHLDMLPARLPAARETWPSPFDLAGVLARRASPVCVLASGDPMLF
GVGATLARQLSPDEWRVLPAPSSLSLAAARLGWALQDVGAVSLVGRPLATLARHLLPGRRLFVLSADGRTPAAVAAELVA
RGFGPTRISVFEHLGGPLERRLDGLAQGWRIDETAALNLVALDCQACPDAPRRALTPGLPDDAYRHDGQLTKRDLRAMTL
GRLAPVPGELLWDVGAGSGSIGIEWMRAHPSCQAIAIEAHAERQRFIEHNRDALGVPGLQLVAGRAPDALAGLAAPDAIF
IGGGATAPGVLDACWAALKPGGRLVANAVTLQGEMALAAWRDAHGGTLTRVSLAHAEPLGRFDTWRQPLPVTLYDVRKPD
TADTPAPSTATNATDA

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2242

COG function: function code H; Precorrin-6B methylase 2

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 43756; Mature: 43624

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: PS00047 HISTONE_H4 ; PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAWLTVVGIGDDGYAGLGRSARRALLDATLVVGAKRHLDMLPARLPAARETWPSPFDLA
CCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHCCCCCHHHH
GVLARRASPVCVLASGDPMLFGVGATLARQLSPDEWRVLPAPSSLSLAAARLGWALQDVG
HHHHHCCCCEEEEECCCCEEEECHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHCC
AVSLVGRPLATLARHLLPGRRLFVLSADGRTPAAVAAELVARGFGPTRISVFEHLGGPLE
HHHHHCCCHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCHHH
RRLDGLAQGWRIDETAALNLVALDCQACPDAPRRALTPGLPDDAYRHDGQLTKRDLRAMT
HHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCHHHCCCCCCCHHHHCCCCHHHHHHHHHH
LGRLAPVPGELLWDVGAGSGSIGIEWMRAHPSCQAIAIEAHAERQRFIEHNRDALGVPGL
HHCCCCCCHHHEEEECCCCCCCCEEEEECCCCCEEEEEEHHHHHHHHHHCCCCCCCCCCH
QLVAGRAPDALAGLAAPDAIFIGGGATAPGVLDACWAALKPGGRLVANAVTLQGEMALAA
HEEECCCCHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCEEEEE
WRDAHGGTLTRVSLAHAEPLGRFDTWRQPLPVTLYDVRKPDTADTPAPSTATNATDA
HHCCCCCEEEEEEEHHCCCCCCHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TAWLTVVGIGDDGYAGLGRSARRALLDATLVVGAKRHLDMLPARLPAARETWPSPFDLA
CEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHCCCCCHHHH
GVLARRASPVCVLASGDPMLFGVGATLARQLSPDEWRVLPAPSSLSLAAARLGWALQDVG
HHHHHCCCCEEEEECCCCEEEECHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHCC
AVSLVGRPLATLARHLLPGRRLFVLSADGRTPAAVAAELVARGFGPTRISVFEHLGGPLE
HHHHHCCCHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCHHH
RRLDGLAQGWRIDETAALNLVALDCQACPDAPRRALTPGLPDDAYRHDGQLTKRDLRAMT
HHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCHHHCCCCCCCHHHHCCCCHHHHHHHHHH
LGRLAPVPGELLWDVGAGSGSIGIEWMRAHPSCQAIAIEAHAERQRFIEHNRDALGVPGL
HHCCCCCCHHHEEEECCCCCCCCEEEEECCCCCEEEEEEHHHHHHHHHHCCCCCCCCCCH
QLVAGRAPDALAGLAAPDAIFIGGGATAPGVLDACWAALKPGGRLVANAVTLQGEMALAA
HEEECCCCHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCEEEEE
WRDAHGGTLTRVSLAHAEPLGRFDTWRQPLPVTLYDVRKPDTADTPAPSTATNATDA
HHCCCCCEEEEEEEHHCCCCCCHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]