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The map label for this gene is hipO [H]

Identifier: 78066267

GI number: 78066267

Start: 1811505

End: 1812668

Strand: Direct

Name: hipO [H]

Synonym: Bcep18194_A4797

Alternate gene names: 78066267

Gene position: 1811505-1812668 (Clockwise)

Preceding gene: 78066264

Following gene: 78066268

Centisome position: 49.04

GC content: 67.78

Gene sequence:

>1164_bases
GTGACGCACAGCGTGATTCCCGCAGGCCTCGCCGACGAAATGATCGAGATCCGGCACCGCATCCACGCCCACCCCGAGCT
CGGCTTCGAGGAATTCGCGACGAGCGACCTCGTCGCGGAGCAACTGCAGTCGTGGGGCTACACGGTGCATCGCGGGCTCG
GCGGCACGGGCGTCGTCGCGCAGCTGAAGGTCGGCAACGGCACGCAGCGGCTCGGCCTGCGCGCCGACATGGACGCGCTG
CCGATCCACGAGGCCACGGGCCTGCCGTACGAGAGCAGGATCGCCGGCAAGATGCACGCGTGCGGCCATGACGGCCACAC
CGCGATGCTGCTGGCGGCCGCGAAGCATCTTGCGCGCGAGCGCCGCTTCTCGGGCACGCTGAACCTGATTTTCCAGCCGG
CCGAGGAAGGGCTCGGCGGCGCGAAGAAGATGCTCGACGAAGGGCTGTTCGAGCTGTTCCCGTGCGACGCGATCTTCGCG
ATGCACAACATGCCCGGCTTCCCGACGGGCAAGTTCGGCTTTCTGCCGGGGTCGTTCATGGCGTCGTCGGATACGGTGAT
CGTCGACGTGCAGGGCCATGGCGGCCACGGGGCGGTGCCGCACAAGACGGTCGATTCGGTGGTCGTCTGCGCGCAGATCG
TCATCGCGCTGCAGACGATCGTGTCGCGCAACGTGTCGCCTCTCGACATGGCGATCGTCACGGTCGGCGCGATCCACGCG
GGCGAGGCGCCGAACGTGATTCCCGATCGCGCGCAGATGCGCCTGTCGGTGCGCGCGCTGAAGCCGGAGGTGCGCGACCT
GCTCGAGACGCGCATCAAGGAAGTCGTGCATGCGCAGGCGGCCGTGTTCGGCGCGTCCGCGACGATCGACTACCAGCGCC
GCTACCCGGTGCTCGTCAACGATGCGGAAATGACCGCGTTCGCGCGCAACGTCGCACGCGAGTGGGTGGGCGACGCGAAC
CTGATCGACGGGATGGTGCCGCTCACCGGCAGCGAGGATTTCGCGTTCCTGCTCGAGAAGCGGCCGGGCTGCTACCTGAT
CATCGGCAATGGCGACGGGGAGGGCGGCTGCATGGTGCACAACCCCGGCTACGATTTCAACGATGCGGCGTTGCCGACCG
GCGCGTCGTACTGGGTGAAGCTGGCGGAGACTTTCCTGGTTTGA

Upstream 100 bases:

>100_bases
GCAACTGACAGTTGCTACCACGACGACTTACCGTCTGCCTGGTTGCCGTCGAACCCACTATCCTTGCCTGCATATTCCCC
ACAGGACAGGAGACGACACC

Downstream 100 bases:

>100_bases
CCGGGGAAACGACGCATACGGCGCGAGGCTGGGCATCGGCATGGTCGCCGCAGCAGCTGAGCGCCTGAAGTACCAAACTT
TGGCAAATGATGGCCGCATT

Product: peptidase M20D, amidohydrolase

Products: NA

Alternate protein names: Benzoylglycine amidohydrolase; Hippuricase [H]

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MTHSVIPAGLADEMIEIRHRIHAHPELGFEEFATSDLVAEQLQSWGYTVHRGLGGTGVVAQLKVGNGTQRLGLRADMDAL
PIHEATGLPYESRIAGKMHACGHDGHTAMLLAAAKHLARERRFSGTLNLIFQPAEEGLGGAKKMLDEGLFELFPCDAIFA
MHNMPGFPTGKFGFLPGSFMASSDTVIVDVQGHGGHGAVPHKTVDSVVVCAQIVIALQTIVSRNVSPLDMAIVTVGAIHA
GEAPNVIPDRAQMRLSVRALKPEVRDLLETRIKEVVHAQAAVFGASATIDYQRRYPVLVNDAEMTAFARNVAREWVGDAN
LIDGMVPLTGSEDFAFLLEKRPGCYLIIGNGDGEGGCMVHNPGYDFNDAALPTGASYWVKLAETFLV

Sequences:

>Translated_387_residues
MTHSVIPAGLADEMIEIRHRIHAHPELGFEEFATSDLVAEQLQSWGYTVHRGLGGTGVVAQLKVGNGTQRLGLRADMDAL
PIHEATGLPYESRIAGKMHACGHDGHTAMLLAAAKHLARERRFSGTLNLIFQPAEEGLGGAKKMLDEGLFELFPCDAIFA
MHNMPGFPTGKFGFLPGSFMASSDTVIVDVQGHGGHGAVPHKTVDSVVVCAQIVIALQTIVSRNVSPLDMAIVTVGAIHA
GEAPNVIPDRAQMRLSVRALKPEVRDLLETRIKEVVHAQAAVFGASATIDYQRRYPVLVNDAEMTAFARNVAREWVGDAN
LIDGMVPLTGSEDFAFLLEKRPGCYLIIGNGDGEGGCMVHNPGYDFNDAALPTGASYWVKLAETFLV
>Mature_386_residues
THSVIPAGLADEMIEIRHRIHAHPELGFEEFATSDLVAEQLQSWGYTVHRGLGGTGVVAQLKVGNGTQRLGLRADMDALP
IHEATGLPYESRIAGKMHACGHDGHTAMLLAAAKHLARERRFSGTLNLIFQPAEEGLGGAKKMLDEGLFELFPCDAIFAM
HNMPGFPTGKFGFLPGSFMASSDTVIVDVQGHGGHGAVPHKTVDSVVVCAQIVIALQTIVSRNVSPLDMAIVTVGAIHAG
EAPNVIPDRAQMRLSVRALKPEVRDLLETRIKEVVHAQAAVFGASATIDYQRRYPVLVNDAEMTAFARNVAREWVGDANL
IDGMVPLTGSEDFAFLLEKRPGCYLIIGNGDGEGGCMVHNPGYDFNDAALPTGASYWVKLAETFLV

Specific function: Required But Not Essential For Aminobenzoyl-Glutamate Utilization. May Participate In Hydrolysis Of Aminobenzoyl- Glutamate To Aminobenzoate, Either Alone Or In Combination With Abgb. [C]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=430, Percent_Identity=26.7441860465116, Blast_Score=101, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.32 [H]

Molecular weight: Translated: 41595; Mature: 41464

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHSVIPAGLADEMIEIRHRIHAHPELGFEEFATSDLVAEQLQSWGYTVHRGLGGTGVVA
CCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEE
QLKVGNGTQRLGLRADMDALPIHEATGLPYESRIAGKMHACGHDGHTAMLLAAAKHLARE
EEEECCCCHHCCCCCCCCCCCCHHHCCCCHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHH
RRFSGTLNLIFQPAEEGLGGAKKMLDEGLFELFPCDAIFAMHNMPGFPTGKFGFLPGSFM
HHCCCEEEEEEECHHHCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCC
ASSDTVIVDVQGHGGHGAVPHKTVDSVVVCAQIVIALQTIVSRNVSPLDMAIVTVGAIHA
CCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEC
GEAPNVIPDRAQMRLSVRALKPEVRDLLETRIKEVVHAQAAVFGASATIDYQRRYPVLVN
CCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEE
DAEMTAFARNVAREWVGDANLIDGMVPLTGSEDFAFLLEKRPGCYLIIGNGDGEGGCMVH
CHHHHHHHHHHHHHHCCCCHHHCCEECCCCCCCCEEEEECCCCEEEEEECCCCCCCEEEE
NPGYDFNDAALPTGASYWVKLAETFLV
CCCCCCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
THSVIPAGLADEMIEIRHRIHAHPELGFEEFATSDLVAEQLQSWGYTVHRGLGGTGVVA
CCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEE
QLKVGNGTQRLGLRADMDALPIHEATGLPYESRIAGKMHACGHDGHTAMLLAAAKHLARE
EEEECCCCHHCCCCCCCCCCCCHHHCCCCHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHH
RRFSGTLNLIFQPAEEGLGGAKKMLDEGLFELFPCDAIFAMHNMPGFPTGKFGFLPGSFM
HHCCCEEEEEEECHHHCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCC
ASSDTVIVDVQGHGGHGAVPHKTVDSVVVCAQIVIALQTIVSRNVSPLDMAIVTVGAIHA
CCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEC
GEAPNVIPDRAQMRLSVRALKPEVRDLLETRIKEVVHAQAAVFGASATIDYQRRYPVLVN
CCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEE
DAEMTAFARNVAREWVGDANLIDGMVPLTGSEDFAFLLEKRPGCYLIIGNGDGEGGCMVH
CHHHHHHHHHHHHHHCCCCHHHCCEECCCCCCCCEEEEECCCCEEEEEECCCCCCCEEEE
NPGYDFNDAALPTGASYWVKLAETFLV
CCCCCCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7730270; 10688204 [H]