Click here to switch to the map view.

The map label for this gene is fimA [H]

Identifier: 78066241

GI number: 78066241

Start: 1770696

End: 1771208

Strand: Direct

Name: fimA [H]

Synonym: Bcep18194_A4771

Alternate gene names: 78066241

Gene position: 1770696-1771208 (Clockwise)

Preceding gene: 78066239

Following gene: 78066242

Centisome position: 47.93

GC content: 63.94

Gene sequence:

>513_bases
ATGAAAAAATCCCTCCTGACCGCTGTCGCACTCGCGGCCCTGTCGACCTCGGCCTTCGCAGCGGGCACCGGCACGATCAC
CTTCAAGGGCGAGATCGTCGCGGGCGCATGCGGCATCGATTCGGGTTCGGTCAACCAGACCGTGCAACTCGGCAAGGTGC
CGACCAACGCGTTCACGAAGGCTGGCGACAAGTCCCAGCCGGTTCCGTTCCAGATCACGCTGACGGATTGCGATACCAGC
GTTGCGAAGCAGGCGAAGTTCACGTTCACGGGCACGTCGAACGCAACGCAGCCGAAGCTGCTCGCGACGATCGGTTCCGC
AACCAACGTCGGCATCCGTCTGCAGAGCGCGTCGGGTGAAGACCTCGACAACGGCGTCGAGCAAGCTGCGCCGACGCTGC
TGTCGAATGGCAACAACATCGTGACGTTCGGCGCGCGCTACGAAGCGACGGCTGCCGGCGTGACGCCGGGTACGGCCGAC
AGCGTCGCGAACTTCACGGTTCGCTACGAGTAA

Upstream 100 bases:

>100_bases
TCTCGATAATGCCGCCTCGTGACGGACGGGAGCCAACCACACGCTGCCGTTTGTGTCCGCCACGTCATCTATTCCATTTG
CACTCCTTACGGGAAACGTC

Downstream 100 bases:

>100_bases
GCGCCTGTATCGGAGGAGGGGTGCGTGCATCCCTTCCTCCCTCTGCTTTCCTTCCTGTTTTCTTCTCCTCGGACTTCCGG
TAGCGCCGCGTGCGAATCAG

Product: fimbrial protein

Products: NA

Alternate protein names: Type-1A pilin [H]

Number of amino acids: Translated: 170; Mature: 170

Protein sequence:

>170_residues
MKKSLLTAVALAALSTSAFAAGTGTITFKGEIVAGACGIDSGSVNQTVQLGKVPTNAFTKAGDKSQPVPFQITLTDCDTS
VAKQAKFTFTGTSNATQPKLLATIGSATNVGIRLQSASGEDLDNGVEQAAPTLLSNGNNIVTFGARYEATAAGVTPGTAD
SVANFTVRYE

Sequences:

>Translated_170_residues
MKKSLLTAVALAALSTSAFAAGTGTITFKGEIVAGACGIDSGSVNQTVQLGKVPTNAFTKAGDKSQPVPFQITLTDCDTS
VAKQAKFTFTGTSNATQPKLLATIGSATNVGIRLQSASGEDLDNGVEQAAPTLLSNGNNIVTFGARYEATAAGVTPGTAD
SVANFTVRYE
>Mature_170_residues
MKKSLLTAVALAALSTSAFAAGTGTITFKGEIVAGACGIDSGSVNQTVQLGKVPTNAFTKAGDKSQPVPFQITLTDCDTS
VAKQAKFTFTGTSNATQPKLLATIGSATNVGIRLQSASGEDLDNGVEQAAPTLLSNGNNIVTFGARYEATAAGVTPGTAD
SVANFTVRYE

Specific function: Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs [H]

COG id: COG3539

COG function: function code NU; P pilus assembly protein, pilin FimA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fimbrial protein family [H]

Homologues:

Organism=Escherichia coli, GI1790769, Length=154, Percent_Identity=43.5064935064935, Blast_Score=100, Evalue=4e-23,
Organism=Escherichia coli, GI87082421, Length=170, Percent_Identity=33.5294117647059, Blast_Score=89, Evalue=1e-19,
Organism=Escherichia coli, GI1789422, Length=186, Percent_Identity=36.5591397849462, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI87081753, Length=153, Percent_Identity=35.9477124183007, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1786746, Length=177, Percent_Identity=34.4632768361582, Blast_Score=76, Evalue=1e-15,
Organism=Escherichia coli, GI87081804, Length=179, Percent_Identity=32.9608938547486, Blast_Score=76, Evalue=1e-15,
Organism=Escherichia coli, GI1789531, Length=196, Percent_Identity=32.6530612244898, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787781, Length=165, Percent_Identity=30.3030303030303, Blast_Score=64, Evalue=4e-12,
Organism=Escherichia coli, GI1790773, Length=179, Percent_Identity=30.1675977653631, Blast_Score=64, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008966
- InterPro:   IPR000259
- InterPro:   IPR014779 [H]

Pfam domain/function: PF00419 Fimbrial [H]

EC number: NA

Molecular weight: Translated: 17210; Mature: 17210

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSLLTAVALAALSTSAFAAGTGTITFKGEIVAGACGIDSGSVNQTVQLGKVPTNAFTK
CCHHHHHHHHHHHHHCCCEECCCCEEEEECEEEEEECCCCCCCCCCEEEECCCCCHHHHC
AGDKSQPVPFQITLTDCDTSVAKQAKFTFTGTSNATQPKLLATIGSATNVGIRLQSASGE
CCCCCCCCEEEEEEECCCCCHHHCEEEEEECCCCCCCCEEEEEECCCCCEEEEEECCCCC
DLDNGVEQAAPTLLSNGNNIVTFGARYEATAAGVTPGTADSVANFTVRYE
CHHHHHHHHCCHHHCCCCEEEEECCCEEEEECCCCCCCCCCCEEEEEEEC
>Mature Secondary Structure
MKKSLLTAVALAALSTSAFAAGTGTITFKGEIVAGACGIDSGSVNQTVQLGKVPTNAFTK
CCHHHHHHHHHHHHHCCCEECCCCEEEEECEEEEEECCCCCCCCCCEEEECCCCCHHHHC
AGDKSQPVPFQITLTDCDTSVAKQAKFTFTGTSNATQPKLLATIGSATNVGIRLQSASGE
CCCCCCCCEEEEEEECCCCCHHHCEEEEEECCCCCCCCEEEEEECCCCCEEEEEECCCCC
DLDNGVEQAAPTLLSNGNNIVTFGARYEATAAGVTPGTADSVANFTVRYE
CHHHHHHHHCCHHHCCCCEEEEECCCEEEEECCCCCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8636962; 11251843; 12657207 [H]