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The map label for this gene is adrA [H]

Identifier: 78066192

GI number: 78066192

Start: 1713408

End: 1714379

Strand: Reverse

Name: adrA [H]

Synonym: Bcep18194_A4722

Alternate gene names: 78066192

Gene position: 1714379-1713408 (Counterclockwise)

Preceding gene: 78066193

Following gene: 78066186

Centisome position: 46.41

GC content: 66.36

Gene sequence:

>972_bases
ATGCAAATCGCACCGAAACCGGCCGACGAGGCGGCCCGGCTCGATACGCTTCATTCGCTCTCGATCCTCGACACGCCGCC
CGAAGAGCGCTTCGATCGCCTGACGCGTCTCGCGCGCAGGCTGTTCGACGTACCGATCGCACTCGTCAGCCTCGTCGACG
ACGATCGCCAGTGGTTCAAGAGCCACGCCGGGCTCGACGTCACGCAAACGTCGCGCGACGTGTCGTTCTGCTCCCATGCA
TTGCTCGAGGGCAATACGATGGTGATCCAGGATGCGCTGAACGACAATCGCTTCCACGACAACCCGCTCGTCACCGGTGC
GCCCGGCATCCGCTTCTACGCGGGCCGACCGCTTACGGCGCCGAACGGCGCACCCATCGGCACGCTGTGCCTGATCGACA
CGCGGCCGCGCTCGCTCGAACCCGACGAACTCGCGCTGCTCGGCGATCTCGCTCACATGACCGAGCGCGAGATCGCGGCG
CTGCATTTCGCGACCACCGACGAGCTCACGCAACTGACCAACCGGCGCGGCTTCGAGATCCTGGCCCGCCACGTGCTGAG
CCTGTGCGATCGCCTTGACCGTCACGCGGCGTTGCTGTTTTTCGACCTGAACGATTTCAAGTCGATCAACGACCGCTTCG
GCCACGCCGAAGGCGACCATGCGCTCAAGGCATTCGCCGATACGTTGACGGGCGCGCTGCGCGACAGCGACGTGATCGCA
CGGCTTGGCGGCGACGAGTTCGTCGTGCTGCTGAGCGCCACCGATCCGGGCGACGTTGCCGAGCCGGTCGAACGCGTGAA
GCAGGCGCTCGCGCGGCGCAACGCGGCCGATGCACGCGGCTATGACATCCGGTTCAGCGTCGGGCACGTCGACTACGATC
CCGCGCACCATCGCGACGTGGCCGACCTGCTCGCATCGGCCGATCAACGGATGTACGAGGACAAGCAGCGCGGCAAGACG
GCCGGCGCGTAA

Upstream 100 bases:

>100_bases
TCGGCAGATTTGCAACGTGGCGATGCGCCGAACAATGCGCGATACTGTCCGACATACGATCCCGTGACCGGCCTCGCAGC
CGGGACAAAAGACAAGGCCC

Downstream 100 bases:

>100_bases
GCGCGGGCGGACCGGGCGCAGGCGCGTGCCGCCGCCCGGCCGTTCAACTGCGCTTGCGTGGTTGCGTCAGCTTCCGCACG
GCGGCGCGCTGGCCATGGCC

Product: diguanylate cyclase with GAF sensor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MQIAPKPADEAARLDTLHSLSILDTPPEERFDRLTRLARRLFDVPIALVSLVDDDRQWFKSHAGLDVTQTSRDVSFCSHA
LLEGNTMVIQDALNDNRFHDNPLVTGAPGIRFYAGRPLTAPNGAPIGTLCLIDTRPRSLEPDELALLGDLAHMTEREIAA
LHFATTDELTQLTNRRGFEILARHVLSLCDRLDRHAALLFFDLNDFKSINDRFGHAEGDHALKAFADTLTGALRDSDVIA
RLGGDEFVVLLSATDPGDVAEPVERVKQALARRNAADARGYDIRFSVGHVDYDPAHHRDVADLLASADQRMYEDKQRGKT
AGA

Sequences:

>Translated_323_residues
MQIAPKPADEAARLDTLHSLSILDTPPEERFDRLTRLARRLFDVPIALVSLVDDDRQWFKSHAGLDVTQTSRDVSFCSHA
LLEGNTMVIQDALNDNRFHDNPLVTGAPGIRFYAGRPLTAPNGAPIGTLCLIDTRPRSLEPDELALLGDLAHMTEREIAA
LHFATTDELTQLTNRRGFEILARHVLSLCDRLDRHAALLFFDLNDFKSINDRFGHAEGDHALKAFADTLTGALRDSDVIA
RLGGDEFVVLLSATDPGDVAEPVERVKQALARRNAADARGYDIRFSVGHVDYDPAHHRDVADLLASADQRMYEDKQRGKT
AGA
>Mature_323_residues
MQIAPKPADEAARLDTLHSLSILDTPPEERFDRLTRLARRLFDVPIALVSLVDDDRQWFKSHAGLDVTQTSRDVSFCSHA
LLEGNTMVIQDALNDNRFHDNPLVTGAPGIRFYAGRPLTAPNGAPIGTLCLIDTRPRSLEPDELALLGDLAHMTEREIAA
LHFATTDELTQLTNRRGFEILARHVLSLCDRLDRHAALLFFDLNDFKSINDRFGHAEGDHALKAFADTLTGALRDSDVIA
RLGGDEFVVLLSATDPGDVAEPVERVKQALARRNAADARGYDIRFSVGHVDYDPAHHRDVADLLASADQRMYEDKQRGKT
AGA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=159, Percent_Identity=37.7358490566038, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI87081977, Length=266, Percent_Identity=31.203007518797, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI87082007, Length=158, Percent_Identity=35.4430379746835, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1788381, Length=208, Percent_Identity=31.25, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI145693134, Length=161, Percent_Identity=29.8136645962733, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI87081881, Length=176, Percent_Identity=27.8409090909091, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787541, Length=157, Percent_Identity=30.5732484076433, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081974, Length=158, Percent_Identity=31.0126582278481, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787802, Length=159, Percent_Identity=28.9308176100629, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787816, Length=178, Percent_Identity=29.2134831460674, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1788085, Length=164, Percent_Identity=28.6585365853659, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1787262, Length=126, Percent_Identity=28.5714285714286, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR007894 [H]

Pfam domain/function: PF00990 GGDEF; PF05230 MASE2 [H]

EC number: NA

Molecular weight: Translated: 35718; Mature: 35718

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIAPKPADEAARLDTLHSLSILDTPPEERFDRLTRLARRLFDVPIALVSLVDDDRQWFK
CCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SHAGLDVTQTSRDVSFCSHALLEGNTMVIQDALNDNRFHDNPLVTGAPGIRFYAGRPLTA
HHCCCCEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEECCCCCEEECCCCCCC
PNGAPIGTLCLIDTRPRSLEPDELALLGDLAHMTEREIAALHFATTDELTQLTNRRGFEI
CCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHCCCCHHH
LARHVLSLCDRLDRHAALLFFDLNDFKSINDRFGHAEGDHALKAFADTLTGALRDSDVIA
HHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHE
RLGGDEFVVLLSATDPGDVAEPVERVKQALARRNAADARGYDIRFSVGHVDYDPAHHRDV
EECCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHH
ADLLASADQRMYEDKQRGKTAGA
HHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQIAPKPADEAARLDTLHSLSILDTPPEERFDRLTRLARRLFDVPIALVSLVDDDRQWFK
CCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SHAGLDVTQTSRDVSFCSHALLEGNTMVIQDALNDNRFHDNPLVTGAPGIRFYAGRPLTA
HHCCCCEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEECCCCCEEECCCCCCC
PNGAPIGTLCLIDTRPRSLEPDELALLGDLAHMTEREIAALHFATTDELTQLTNRRGFEI
CCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHCCCCHHH
LARHVLSLCDRLDRHAALLFFDLNDFKSINDRFGHAEGDHALKAFADTLTGALRDSDVIA
HHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHE
RLGGDEFVVLLSATDPGDVAEPVERVKQALARRNAADARGYDIRFSVGHVDYDPAHHRDV
EECCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHH
ADLLASADQRMYEDKQRGKTAGA
HHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]