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The map label for this gene is nanT [H]

Identifier: 78066146

GI number: 78066146

Start: 1667953

End: 1669215

Strand: Reverse

Name: nanT [H]

Synonym: Bcep18194_A4676

Alternate gene names: 78066146

Gene position: 1669215-1667953 (Counterclockwise)

Preceding gene: 78066150

Following gene: 78066145

Centisome position: 45.19

GC content: 65.8

Gene sequence:

>1263_bases
ATGCACATCGCGAGCGCGCAAGCCAACGAGGAGACCTCGGACATGAGCTGGACCCGCGAACAACGCAACGTCACGATCGC
CGCCTACCTGGGCTGGACACTCGATGCGTTCGACTTCTTCCTGATGGTCTTCGTGCTGAAGGACATCGCCGCCGAATTCG
GGTCGACGATTCCCGCCGTCGCGTTCGCGCTCACACTGACGCTCGCGATGCGCCCGCTCGGCGCACTGATCTTCGGCCGG
CTCGCCGATCGCTTCGGCCGCCGTCCGACGCTGATGGTCAACATCGCGTGCTACTCGCTGCTCGAACTCGCATCGGGTTT
CGCGCCGAGCCTGACCGCACTGCTCGTGTTGCGCGCGTTGTTCGGCGTCGCGATGGGCGGCGAATGGGGCGTCGGCTCGG
CACTGACGATGGAAACCGTGCCGACCCATGCGCGCGGCTTTGTATCGGGGCTGCTGCAGGCCGGCTATCCGAGCGGCTAC
CTGCTTGCGTCCGTCGTGTTCGGCCTGTTCTACCAGTACATCGGCTGGCGCGGGATGTTCATGGTCGGCGTGCTGCCCGC
GCTGCTCGTGCTGTACGTGCGCGCTCACGTGCCCGAATCGCCGGCGTGGAAGCAGATGGAGAAGCGCCCGCGCCCGAGCC
TGGGCACCACGCTGAAGCAGAACTGGAAGCTCACGATCTACGCGATCGTCCTGATGACCGCGTTCAACTTCTTCTCGCAC
GGCACGCAGGATCTCTACCCGACGTTCCTGCGCGAACAGCATCACTTCGATCCGCATACCGTGTCGTGGATCACGATCGT
GCTGAACATCGGCGCCATCGTCGGCGGCCTGTCGTTCGGCGCGATCTCGGAACGGATCGGCCGGCGTCGTGCCATCTTCA
TCGCGGCGTTGATCGCCCTGCCCGTGCTGCCGCTGTGGGCGTTCTCGAGCGGCCCGGTCGCCCTCGCCGCGGGCGCGTTC
CTGATGCAGATCTCGGTGCAGGGTGCGTGGGGCGTGATCCCGGTTCACCTGAACGAGATCTCGCCCGACGAGCTCCGCGC
GACCTTCCCGGGCGTCGTCTACCAGCTCGGCAACCTGCTCGCGTCGGGCAACGCGACGATGCAGGCCTCGCTCGCCGTTT
CGAACAACAACAATTACAGCTTCGCGCTCGCGCTCGTGGCCGGCATCGTCGCCGTCGTGATCGCCGTGCTGATCCTGTTC
AGCCGCGAGCGGCGCGGCATCGACATGACGCAATCGGTCAATACGCGTAGCACGGTCACCTGA

Upstream 100 bases:

>100_bases
ATTATTCCCGATTCGACGTTATCGCGCCCCACATCGTCCGGCGTCGCGGCCTACACTCGATCAATGCCCCCGCACCGCGC
GCAAGCCGGCCGGCATCCGC

Downstream 100 bases:

>100_bases
ACCCGCGCGTTGCCGCACCGCATCATCGCGTGTGCCCCGTCCCGCCGAGGGCACGCGCGATACTTTCCGCATTCGCACAT
CGAACTAGAGGAATTTGTCC

Product: major facilitator transporter

Products: NA

Alternate protein names: Sialic acid permease [H]

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MHIASAQANEETSDMSWTREQRNVTIAAYLGWTLDAFDFFLMVFVLKDIAAEFGSTIPAVAFALTLTLAMRPLGALIFGR
LADRFGRRPTLMVNIACYSLLELASGFAPSLTALLVLRALFGVAMGGEWGVGSALTMETVPTHARGFVSGLLQAGYPSGY
LLASVVFGLFYQYIGWRGMFMVGVLPALLVLYVRAHVPESPAWKQMEKRPRPSLGTTLKQNWKLTIYAIVLMTAFNFFSH
GTQDLYPTFLREQHHFDPHTVSWITIVLNIGAIVGGLSFGAISERIGRRRAIFIAALIALPVLPLWAFSSGPVALAAGAF
LMQISVQGAWGVIPVHLNEISPDELRATFPGVVYQLGNLLASGNATMQASLAVSNNNNYSFALALVAGIVAVVIAVLILF
SRERRGIDMTQSVNTRSTVT

Sequences:

>Translated_420_residues
MHIASAQANEETSDMSWTREQRNVTIAAYLGWTLDAFDFFLMVFVLKDIAAEFGSTIPAVAFALTLTLAMRPLGALIFGR
LADRFGRRPTLMVNIACYSLLELASGFAPSLTALLVLRALFGVAMGGEWGVGSALTMETVPTHARGFVSGLLQAGYPSGY
LLASVVFGLFYQYIGWRGMFMVGVLPALLVLYVRAHVPESPAWKQMEKRPRPSLGTTLKQNWKLTIYAIVLMTAFNFFSH
GTQDLYPTFLREQHHFDPHTVSWITIVLNIGAIVGGLSFGAISERIGRRRAIFIAALIALPVLPLWAFSSGPVALAAGAF
LMQISVQGAWGVIPVHLNEISPDELRATFPGVVYQLGNLLASGNATMQASLAVSNNNNYSFALALVAGIVAVVIAVLILF
SRERRGIDMTQSVNTRSTVT
>Mature_420_residues
MHIASAQANEETSDMSWTREQRNVTIAAYLGWTLDAFDFFLMVFVLKDIAAEFGSTIPAVAFALTLTLAMRPLGALIFGR
LADRFGRRPTLMVNIACYSLLELASGFAPSLTALLVLRALFGVAMGGEWGVGSALTMETVPTHARGFVSGLLQAGYPSGY
LLASVVFGLFYQYIGWRGMFMVGVLPALLVLYVRAHVPESPAWKQMEKRPRPSLGTTLKQNWKLTIYAIVLMTAFNFFSH
GTQDLYPTFLREQHHFDPHTVSWITIVLNIGAIVGGLSFGAISERIGRRRAIFIAALIALPVLPLWAFSSGPVALAAGAF
LMQISVQGAWGVIPVHLNEISPDELRATFPGVVYQLGNLLASGNATMQASLAVSNNNNYSFALALVAGIVAVVIAVLILF
SRERRGIDMTQSVNTRSTVT

Specific function: May be a sugar-cation symporter involved in sialic acid uptake [H]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter family. Sialic acid transporter (TC 2.A.1.12.1) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082404, Length=351, Percent_Identity=28.7749287749288, Blast_Score=158, Evalue=7e-40,
Organism=Escherichia coli, GI87082231, Length=208, Percent_Identity=33.6538461538462, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1790550, Length=394, Percent_Identity=25.8883248730964, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1788292, Length=466, Percent_Identity=25.5364806866953, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1786229, Length=446, Percent_Identity=22.8699551569507, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87081723, Length=341, Percent_Identity=28.4457478005865, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1789941, Length=448, Percent_Identity=25, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1787880, Length=180, Percent_Identity=26.1111111111111, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788942, Length=448, Percent_Identity=25, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI32564663, Length=210, Percent_Identity=24.2857142857143, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17542342, Length=135, Percent_Identity=37.037037037037, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322632, Length=444, Percent_Identity=27.7027027027027, Blast_Score=170, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6320595, Length=132, Percent_Identity=31.8181818181818, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR004742 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45622; Mature: 45622

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHIASAQANEETSDMSWTREQRNVTIAAYLGWTLDAFDFFLMVFVLKDIAAEFGSTIPAV
CCCCCCCCCCCCCCCHHHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AFALTLTLAMRPLGALIFGRLADRFGRRPTLMVNIACYSLLELASGFAPSLTALLVLRAL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHH
FGVAMGGEWGVGSALTMETVPTHARGFVSGLLQAGYPSGYLLASVVFGLFYQYIGWRGMF
HHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHH
MVGVLPALLVLYVRAHVPESPAWKQMEKRPRPSLGTTLKQNWKLTIYAIVLMTAFNFFSH
HHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHC
GTQDLYPTFLREQHHFDPHTVSWITIVLNIGAIVGGLSFGAISERIGRRRAIFIAALIAL
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHH
PVLPLWAFSSGPVALAAGAFLMQISVQGAWGVIPVHLNEISPDELRATFPGVVYQLGNLL
HHHHHHCCCCCCHHHHHHHHHEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHH
ASGNATMQASLAVSNNNNYSFALALVAGIVAVVIAVLILFSRERRGIDMTQSVNTRSTVT
HCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCC
>Mature Secondary Structure
MHIASAQANEETSDMSWTREQRNVTIAAYLGWTLDAFDFFLMVFVLKDIAAEFGSTIPAV
CCCCCCCCCCCCCCCHHHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AFALTLTLAMRPLGALIFGRLADRFGRRPTLMVNIACYSLLELASGFAPSLTALLVLRAL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHH
FGVAMGGEWGVGSALTMETVPTHARGFVSGLLQAGYPSGYLLASVVFGLFYQYIGWRGMF
HHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHH
MVGVLPALLVLYVRAHVPESPAWKQMEKRPRPSLGTTLKQNWKLTIYAIVLMTAFNFFSH
HHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHC
GTQDLYPTFLREQHHFDPHTVSWITIVLNIGAIVGGLSFGAISERIGRRRAIFIAALIAL
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHH
PVLPLWAFSSGPVALAAGAFLMQISVQGAWGVIPVHLNEISPDELRATFPGVVYQLGNLL
HHHHHHCCCCCCHHHHHHHHHEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHH
ASGNATMQASLAVSNNNNYSFALALVAGIVAVVIAVLILFSRERRGIDMTQSVNTRSTVT
HCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA