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The map label for this gene is ptxR [H]

Identifier: 78066048

GI number: 78066048

Start: 1553001

End: 1553936

Strand: Direct

Name: ptxR [H]

Synonym: Bcep18194_A4577

Alternate gene names: 78066048

Gene position: 1553001-1553936 (Clockwise)

Preceding gene: 78066046

Following gene: 78066049

Centisome position: 42.04

GC content: 71.15

Gene sequence:

>936_bases
ATGAATCAGCAAAATGTCCAGGCGCTCTGGCCGCATATCCATTCGCTGACGGTGCTGGCCGCGGCCGGCAGTTTCACCGC
CGCCGCGCAGCGGCTCGGCATCAGCAAGGCCGCGATGAGCCAGCGCATCGCCGATCTCGAAAAGGCCGCCGGCGTGCCGC
TCGTGCGTCGCACGACACGCAGCGTGCGGCTCACCGACGCGGGCCAGACGCTCGTCGACAGCACGCGCGACGCGTTCGAG
TCGATCGGGCAGCACTTTGCGCGCGTGAAGGATCTCGCCGGAGAACCGCGCGGCCTGCTGCGCCTGACGGTGCCGGTCGC
GCTCGGGCGCCAGCAGGTCGTGCCGCACCTGCCCGATTTCCTGCGGCAGCATCCGGGCGTGCAGATCGAGCTCGACCTGT
CGGACCGGCTGCATTCGCTGACGCAGGAGGGTTTCGACCTCGCGATCCGCCATACAACCACTGCGCCGCAAACCCACGTC
GCGTGGAAGCTGTGCGATACGCGTTCGCTGCTCGTCGCGAGCCGCGACTACCTCGACGCGCGCGGCGCGCCGCGCCACCC
GAGCGAGCTCGTCGATCACAGCTGCCTGTGCTACCTGCGCGACAACGAGCCGGCCGCCTGGAGTTTCGAGCCGCACGGCC
GGCGGCGCGAGCGTGTGAGCGTGCCGGTGCGCGGCAGCTTCGCGGCGAACAACAGCGAGGCGATGCGCGAGGCCGCGCTC
GGCGGGCTCGGCATCGCGCTGCTACCGGATTTCAGCGCGCAGCGCGACCTTGACGCCGGCCGGCTGGTCGCGTTGCTCGA
CGGCTGGCGGCCGTCGGGCGCGTTCGGCGACCACATCTTCGCGATCCGCCCGTACAGCCCGGTCGTGCCGAGCGCGGTGC
GCGCGCTCGTTCGGCACCTGCGCGAACGGCTTGCGGGCGGCTTTTCGGGCACCTGA

Upstream 100 bases:

>100_bases
GATCGGGTGAGGGTGGACAGCGCCCAGTCTAGGCAAACGCGCAGGGCGGGAGAAGGCCGCGCAGCTTGATTCACTGTTCA
GAATTCTGAATAATCACCGG

Downstream 100 bases:

>100_bases
GCCCGGCGGCGCGGGCGCCGGGCTGCTGCCGGCCCGGGCAGGCAAGGCGGCGCTGCGGTAAAATCCCGGCTTCTCTCCGC
GCCTTGAATGGCGCGTCATT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MNQQNVQALWPHIHSLTVLAAAGSFTAAAQRLGISKAAMSQRIADLEKAAGVPLVRRTTRSVRLTDAGQTLVDSTRDAFE
SIGQHFARVKDLAGEPRGLLRLTVPVALGRQQVVPHLPDFLRQHPGVQIELDLSDRLHSLTQEGFDLAIRHTTTAPQTHV
AWKLCDTRSLLVASRDYLDARGAPRHPSELVDHSCLCYLRDNEPAAWSFEPHGRRRERVSVPVRGSFAANNSEAMREAAL
GGLGIALLPDFSAQRDLDAGRLVALLDGWRPSGAFGDHIFAIRPYSPVVPSAVRALVRHLRERLAGGFSGT

Sequences:

>Translated_311_residues
MNQQNVQALWPHIHSLTVLAAAGSFTAAAQRLGISKAAMSQRIADLEKAAGVPLVRRTTRSVRLTDAGQTLVDSTRDAFE
SIGQHFARVKDLAGEPRGLLRLTVPVALGRQQVVPHLPDFLRQHPGVQIELDLSDRLHSLTQEGFDLAIRHTTTAPQTHV
AWKLCDTRSLLVASRDYLDARGAPRHPSELVDHSCLCYLRDNEPAAWSFEPHGRRRERVSVPVRGSFAANNSEAMREAAL
GGLGIALLPDFSAQRDLDAGRLVALLDGWRPSGAFGDHIFAIRPYSPVVPSAVRALVRHLRERLAGGFSGT
>Mature_311_residues
MNQQNVQALWPHIHSLTVLAAAGSFTAAAQRLGISKAAMSQRIADLEKAAGVPLVRRTTRSVRLTDAGQTLVDSTRDAFE
SIGQHFARVKDLAGEPRGLLRLTVPVALGRQQVVPHLPDFLRQHPGVQIELDLSDRLHSLTQEGFDLAIRHTTTAPQTHV
AWKLCDTRSLLVASRDYLDARGAPRHPSELVDHSCLCYLRDNEPAAWSFEPHGRRRERVSVPVRGSFAANNSEAMREAAL
GGLGIALLPDFSAQRDLDAGRLVALLDGWRPSGAFGDHIFAIRPYSPVVPSAVRALVRHLRERLAGGFSGT

Specific function: Transcriptional activator of the toxA (exotoxin) and regA genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=277, Percent_Identity=30.3249097472924, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787128, Length=257, Percent_Identity=30.7392996108949, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI87081978, Length=299, Percent_Identity=29.4314381270903, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1787589, Length=262, Percent_Identity=30.1526717557252, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI145693193, Length=265, Percent_Identity=29.811320754717, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1786401, Length=288, Percent_Identity=27.4305555555556, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1790011, Length=311, Percent_Identity=26.6881028938907, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789639, Length=249, Percent_Identity=27.710843373494, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1788706, Length=260, Percent_Identity=28.8461538461538, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789173, Length=258, Percent_Identity=28.6821705426357, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI157672245, Length=120, Percent_Identity=35.8333333333333, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786448, Length=244, Percent_Identity=26.2295081967213, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786713, Length=265, Percent_Identity=30.5660377358491, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33988; Mature: 33988

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQQNVQALWPHIHSLTVLAAAGSFTAAAQRLGISKAAMSQRIADLEKAAGVPLVRRTTR
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEECCCC
SVRLTDAGQTLVDSTRDAFESIGQHFARVKDLAGEPRGLLRLTVPVALGRQQVVPHLPDF
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHCCCHHHHHHHHHH
LRQHPGVQIELDLSDRLHSLTQEGFDLAIRHTTTAPQTHVAWKLCDTRSLLVASRDYLDA
HHHCCCCEEEEEHHHHHHHHHHCCCEEEEEECCCCCCHHEEEEECCCHHHHHHHHHHHCC
RGAPRHPSELVDHSCLCYLRDNEPAAWSFEPHGRRRERVSVPVRGSFAANNSEAMREAAL
CCCCCCHHHHHCCCEEEEEECCCCCEECCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHH
GGLGIALLPDFSAQRDLDAGRLVALLDGWRPSGAFGDHIFAIRPYSPVVPSAVRALVRHL
CCCCEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHH
RERLAGGFSGT
HHHHCCCCCCC
>Mature Secondary Structure
MNQQNVQALWPHIHSLTVLAAAGSFTAAAQRLGISKAAMSQRIADLEKAAGVPLVRRTTR
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEECCCC
SVRLTDAGQTLVDSTRDAFESIGQHFARVKDLAGEPRGLLRLTVPVALGRQQVVPHLPDF
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHCCCHHHHHHHHHH
LRQHPGVQIELDLSDRLHSLTQEGFDLAIRHTTTAPQTHVAWKLCDTRSLLVASRDYLDA
HHHCCCCEEEEEHHHHHHHHHHCCCEEEEEECCCCCCHHEEEEECCCHHHHHHHHHHHCC
RGAPRHPSELVDHSCLCYLRDNEPAAWSFEPHGRRRERVSVPVRGSFAANNSEAMREAAL
CCCCCCHHHHHCCCEEEEEECCCCCEECCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHH
GGLGIALLPDFSAQRDLDAGRLVALLDGWRPSGAFGDHIFAIRPYSPVVPSAVRALVRHL
CCCCEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHH
RERLAGGFSGT
HHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8843437; 10984043 [H]