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The map label for this gene is iolE [H]

Identifier: 78066044

GI number: 78066044

Start: 1547972

End: 1548898

Strand: Direct

Name: iolE [H]

Synonym: Bcep18194_A4573

Alternate gene names: 78066044

Gene position: 1547972-1548898 (Clockwise)

Preceding gene: 78066043

Following gene: 78066045

Centisome position: 41.9

GC content: 68.18

Gene sequence:

>927_bases
ATGACGATGAAGATGGGTTGCGCACCGTGCTGCTGGGGTGTCGACGACGTGAAGAACCCGCACTTGCCGCCGTGGCGGCA
GGTGCTTGCCGAAGCTGCCTCGGCCGGCTACTCGGGCATCGAGCTCGGGCCGTACGGCTACATCCCGCTCGAACTCGACG
TGGTGAGTGCCGAGCTGGAGCGACAGCGCCTGAGCATCACGGCCGGCACGATTTTCGACGATCTGGTGTCGCCCGAGAAT
CTGCCGAACCTGCTGCGCCAGACGCGCGACATCTGCGCGCTGATCACGCGGCTGCCGAAACTGCCGACGCAGGACGGCCA
GCGCTACGCGGCGCCGTACCTGGTCGTGATGGACTGGGGCCACGAGGAACGCGACTACGCGGCCGGTCATGGCGATCGTG
CGCCGCGGCTGTCGGACGAAAGCTGGGCGGCGATGGTCGGGCACATCCGGCAGATCGCGACGATCGCACGCGACGAATTC
GGCGTGCGCACGGTGATTCATCCGCATGCGGGCGGCTACATCGAGTTCGCTGACGAGATCGACCGGATCGTCGCCGACGT
GCCGGCCGACACGGCCGGCCTCTGTCTCGACACGGGCCACCTGTACTACTCGGGCATGGACCCGGAGGCCTGGCTGCGCC
GCCACGCGGCGCGTCTCGACTACGTGCATTTCAAGGACATCGACGCGGCCGTGTACGACGCGGTGATGGGCGAGCACATC
GCGTTCTTCGCTGCCTGCGCGCGCGGCGTGATGTGCCCGATCGGCACCGGCGTGCTCGACTACCGGTCGATCCGGCAGGC
GCTCGACGACATCGCCTACGCGGGCTACATCACGATCGAGCAGGAACGCGACCCGCGCAATGCCGGCACGAGCTTGCGCG
ACGTCGCCGCGAGCCGCGCGTTTCTCGCGTCGGCCGGCTTCGCATGA

Upstream 100 bases:

>100_bases
GTGCGCAGAAGAGCGGGGCGGTCGAGCCGATCGCGATGGCCGAACGCCCTGCGTTCTACCGCGGCTGAACCGCAGCCGCC
TATCTGCCGGACTGACCGAC

Downstream 100 bases:

>100_bases
TGCGGCGCACCCTGCACCCCCTGAACTGAACACGGACCTGGAACACTACCATCATGATTGACGGACAGATTCTGCTTGGA
CATTCGATTCGCTGGGGCAT

Product: xylose isomerase-like TIM barrel

Products: NA

Alternate protein names: 2-keto-myo-inositol dehydratase; 2KMI dehydratase [H]

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MTMKMGCAPCCWGVDDVKNPHLPPWRQVLAEAASAGYSGIELGPYGYIPLELDVVSAELERQRLSITAGTIFDDLVSPEN
LPNLLRQTRDICALITRLPKLPTQDGQRYAAPYLVVMDWGHEERDYAAGHGDRAPRLSDESWAAMVGHIRQIATIARDEF
GVRTVIHPHAGGYIEFADEIDRIVADVPADTAGLCLDTGHLYYSGMDPEAWLRRHAARLDYVHFKDIDAAVYDAVMGEHI
AFFAACARGVMCPIGTGVLDYRSIRQALDDIAYAGYITIEQERDPRNAGTSLRDVAASRAFLASAGFA

Sequences:

>Translated_308_residues
MTMKMGCAPCCWGVDDVKNPHLPPWRQVLAEAASAGYSGIELGPYGYIPLELDVVSAELERQRLSITAGTIFDDLVSPEN
LPNLLRQTRDICALITRLPKLPTQDGQRYAAPYLVVMDWGHEERDYAAGHGDRAPRLSDESWAAMVGHIRQIATIARDEF
GVRTVIHPHAGGYIEFADEIDRIVADVPADTAGLCLDTGHLYYSGMDPEAWLRRHAARLDYVHFKDIDAAVYDAVMGEHI
AFFAACARGVMCPIGTGVLDYRSIRQALDDIAYAGYITIEQERDPRNAGTSLRDVAASRAFLASAGFA
>Mature_307_residues
TMKMGCAPCCWGVDDVKNPHLPPWRQVLAEAASAGYSGIELGPYGYIPLELDVVSAELERQRLSITAGTIFDDLVSPENL
PNLLRQTRDICALITRLPKLPTQDGQRYAAPYLVVMDWGHEERDYAAGHGDRAPRLSDESWAAMVGHIRQIATIARDEFG
VRTVIHPHAGGYIEFADEIDRIVADVPADTAGLCLDTGHLYYSGMDPEAWLRRHAARLDYVHFKDIDAAVYDAVMGEHIA
FFAACARGVMCPIGTGVLDYRSIRQALDDIAYAGYITIEQERDPRNAGTSLRDVAASRAFLASAGFA

Specific function: Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D- (3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) [H]

COG id: COG1082

COG function: function code G; Sugar phosphate isomerases/epimerases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iolE/mocC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: =4.2.1.44 [H]

Molecular weight: Translated: 33868; Mature: 33736

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMKMGCAPCCWGVDDVKNPHLPPWRQVLAEAASAGYSGIELGPYGYIPLELDVVSAELE
CCCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHCCCCCCEECCCCEEEEEEEHHHHHHH
RQRLSITAGTIFDDLVSPENLPNLLRQTRDICALITRLPKLPTQDGQRYAAPYLVVMDWG
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCEEEEEECC
HEERDYAAGHGDRAPRLSDESWAAMVGHIRQIATIARDEFGVRTVIHPHAGGYIEFADEI
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEHHHHH
DRIVADVPADTAGLCLDTGHLYYSGMDPEAWLRRHAARLDYVHFKDIDAAVYDAVMGEHI
HHHHHCCCCCCCCEEEECCCEEECCCCHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHH
AFFAACARGVMCPIGTGVLDYRSIRQALDDIAYAGYITIEQERDPRNAGTSLRDVAASRA
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHHH
FLASAGFA
HHHHCCCC
>Mature Secondary Structure 
TMKMGCAPCCWGVDDVKNPHLPPWRQVLAEAASAGYSGIELGPYGYIPLELDVVSAELE
CCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHCCCCCCEECCCCEEEEEEEHHHHHHH
RQRLSITAGTIFDDLVSPENLPNLLRQTRDICALITRLPKLPTQDGQRYAAPYLVVMDWG
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCEEEEEECC
HEERDYAAGHGDRAPRLSDESWAAMVGHIRQIATIARDEFGVRTVIHPHAGGYIEFADEI
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEHHHHH
DRIVADVPADTAGLCLDTGHLYYSGMDPEAWLRRHAARLDYVHFKDIDAAVYDAVMGEHI
HHHHHCCCCCCCCEEEECCCEEECCCCHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHH
AFFAACARGVMCPIGTGVLDYRSIRQALDDIAYAGYITIEQERDPRNAGTSLRDVAASRA
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHHH
FLASAGFA
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA