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The map label for this gene is yafC [H]

Identifier: 78066008

GI number: 78066008

Start: 1508616

End: 1509539

Strand: Reverse

Name: yafC [H]

Synonym: Bcep18194_A4537

Alternate gene names: 78066008

Gene position: 1509539-1508616 (Counterclockwise)

Preceding gene: 78066016

Following gene: 78066006

Centisome position: 40.86

GC content: 68.29

Gene sequence:

>924_bases
ATGCAACACCTTCCTGATCTCGAAGCCTGGGCCATCTTTGCGCGCGTCGCGGAGACCGGTTCGTTCGCGAAAGCCGCCGA
TCTGCTCGGCGTATCGCAGCCAACCGTGTCGAAGGCCATCGCGCGCCTCGAAAAGCGCCTCGGCGCGATGCTGCTGTACC
GCACGTCGCGCAAGCTGTCGCTCACGCCGACCGGCGAACTGCTGCGCGACCGCGCGATCCGCCTGCTCGCCGATGCGGAA
CTGATCGAGAGCGAAGCGTCCGCGCAGGCACTCGAACCGCACGGCCTCGTACGCGTGAATGCGCCGATGTCGTTCGGGCT
GCGCCATCTGTCGCCGGTGCTGCCCGCGTTTCTCGAACGCTATCCGCGCGTCGACATCGACCTCGTGCTCACCGATCACA
TCGTCGACATCGTGTCCGGCGGCTTCGACGTCGCGATCCGCATCGCCGAGCTGAGCGATTCATCGCTGCGCTCGCGCCGG
CTCTGCGCCGTGCGCCGGCCGCTCGTCGCGTCGCCCGCGTACCTCGACCGGCGCGGCCGCCCCACGCATCCGCGCGACAT
CGAACAGCACGTGTGCCTCACCTACACGAACCTGCCGACGCCCGAACACTGGCGCTTCCGCCAGCCGGCATCGGGCGATG
AAGTCGGCGTATCCGTGCACGGCCGCATCCGCACCAACAACGCGGACGTGATCGTCCCCGCGCTCATCGCCGGTCATGGC
CTCGCGCTGCAGCCCGAGTTCCTGGTGTGGGAAGCGATGCAGAACGGCGAGCTCGAGGAAGTGATGTCCGACTGGAAGAT
CGCCGACATCAACGTCAACCTCGTCACGCCGCCCGGCATGCTGCGCGCCGCGCGCGTGACGGTGCTGCTCGACTTCCTCG
CGGAGCACTTCTCGCACGCGCCGTGGGCGCTGCCCGCAACCTGA

Upstream 100 bases:

>100_bases
ATAACGATTTTTCTCCCGGCCGGATTAGAATCACCTGCATCGCACGCCCGCTTTCGCGGTGCGCTGCATCCGTTCCGCTT
CCCTGCCATTCATCCCGACC

Downstream 100 bases:

>100_bases
ACCCGCAACGGCCGGCGACAGCAGATCGCCACGGCCGGCCGTTGCCACGATCGCGGCCGGGGTCCGTTACTTCGCCGGCA
CCGCCGCAATCGACTCGTGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MQHLPDLEAWAIFARVAETGSFAKAADLLGVSQPTVSKAIARLEKRLGAMLLYRTSRKLSLTPTGELLRDRAIRLLADAE
LIESEASAQALEPHGLVRVNAPMSFGLRHLSPVLPAFLERYPRVDIDLVLTDHIVDIVSGGFDVAIRIAELSDSSLRSRR
LCAVRRPLVASPAYLDRRGRPTHPRDIEQHVCLTYTNLPTPEHWRFRQPASGDEVGVSVHGRIRTNNADVIVPALIAGHG
LALQPEFLVWEAMQNGELEEVMSDWKIADINVNLVTPPGMLRAARVTVLLDFLAEHFSHAPWALPAT

Sequences:

>Translated_307_residues
MQHLPDLEAWAIFARVAETGSFAKAADLLGVSQPTVSKAIARLEKRLGAMLLYRTSRKLSLTPTGELLRDRAIRLLADAE
LIESEASAQALEPHGLVRVNAPMSFGLRHLSPVLPAFLERYPRVDIDLVLTDHIVDIVSGGFDVAIRIAELSDSSLRSRR
LCAVRRPLVASPAYLDRRGRPTHPRDIEQHVCLTYTNLPTPEHWRFRQPASGDEVGVSVHGRIRTNNADVIVPALIAGHG
LALQPEFLVWEAMQNGELEEVMSDWKIADINVNLVTPPGMLRAARVTVLLDFLAEHFSHAPWALPAT
>Mature_307_residues
MQHLPDLEAWAIFARVAETGSFAKAADLLGVSQPTVSKAIARLEKRLGAMLLYRTSRKLSLTPTGELLRDRAIRLLADAE
LIESEASAQALEPHGLVRVNAPMSFGLRHLSPVLPAFLERYPRVDIDLVLTDHIVDIVSGGFDVAIRIAELSDSSLRSRR
LCAVRRPLVASPAYLDRRGRPTHPRDIEQHVCLTYTNLPTPEHWRFRQPASGDEVGVSVHGRIRTNNADVIVPALIAGHG
LALQPEFLVWEAMQNGELEEVMSDWKIADINVNLVTPPGMLRAARVTVLLDFLAEHFSHAPWALPAT

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=295, Percent_Identity=34.9152542372881, Blast_Score=176, Evalue=1e-45,
Organism=Escherichia coli, GI1787128, Length=291, Percent_Identity=28.8659793814433, Blast_Score=134, Evalue=9e-33,
Organism=Escherichia coli, GI87081978, Length=303, Percent_Identity=31.023102310231, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI145693193, Length=288, Percent_Identity=30.2083333333333, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1789639, Length=260, Percent_Identity=31.1538461538462, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1789440, Length=283, Percent_Identity=25.0883392226148, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787589, Length=267, Percent_Identity=30.7116104868914, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1789173, Length=268, Percent_Identity=29.1044776119403, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1789506, Length=261, Percent_Identity=25.2873563218391, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1790399, Length=113, Percent_Identity=36.283185840708, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI157672245, Length=116, Percent_Identity=35.3448275862069, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790208, Length=144, Percent_Identity=31.25, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33945; Mature: 33945

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHLPDLEAWAIFARVAETGSFAKAADLLGVSQPTVSKAIARLEKRLGAMLLYRTSRKLS
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHEEEEECCCEEE
LTPTGELLRDRAIRLLADAELIESEASAQALEPHGLVRVNAPMSFGLRHLSPVLPAFLER
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHH
YPRVDIDLVLTDHIVDIVSGGFDVAIRIAELSDSSLRSRRLCAVRRPLVASPAYLDRRGR
CCCCCEEEEEHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCCHHHHCCCC
PTHPRDIEQHVCLTYTNLPTPEHWRFRQPASGDEVGVSVHGRIRTNNADVIVPALIAGHG
CCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCEEEEHHHCCCC
LALQPEFLVWEAMQNGELEEVMSDWKIADINVNLVTPPGMLRAARVTVLLDFLAEHFSHA
CEECCHHHHHEHHCCCCHHHHHCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCC
PWALPAT
CCCCCCC
>Mature Secondary Structure
MQHLPDLEAWAIFARVAETGSFAKAADLLGVSQPTVSKAIARLEKRLGAMLLYRTSRKLS
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHEEEEECCCEEE
LTPTGELLRDRAIRLLADAELIESEASAQALEPHGLVRVNAPMSFGLRHLSPVLPAFLER
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHH
YPRVDIDLVLTDHIVDIVSGGFDVAIRIAELSDSSLRSRRLCAVRRPLVASPAYLDRRGR
CCCCCEEEEEHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCCHHHHCCCC
PTHPRDIEQHVCLTYTNLPTPEHWRFRQPASGDEVGVSVHGRIRTNNADVIVPALIAGHG
CCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCEEEEHHHCCCC
LALQPEFLVWEAMQNGELEEVMSDWKIADINVNLVTPPGMLRAARVTVLLDFLAEHFSHA
CEECCHHHHHEHHCCCCHHHHHCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCC
PWALPAT
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]