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The map label for this gene is yegE [C]

Identifier: 78065994

GI number: 78065994

Start: 1488116

End: 1489315

Strand: Reverse

Name: yegE [C]

Synonym: Bcep18194_A4523

Alternate gene names: 78065994

Gene position: 1489315-1488116 (Counterclockwise)

Preceding gene: 78065995

Following gene: 78065989

Centisome position: 40.32

GC content: 69.5

Gene sequence:

>1200_bases
ATGGTAAGAATTGCGCCGTTGTCGCCCGGCAGGCCGGACGGCATACTGCCGGCGCGGTGCGGCTGGCCGGCGGCGGTCCG
TTGCAGACCGCCCCGCCTGAACGCGCGGCCGCGAGGCGGCGCGTATGCTACCGCAATCCCGAGCCGCCGGACGTGCTTTC
TTTCACGGAAAACTGACTTGAATCAAATCGTCGACACTGCCACCCCGTCCCCCGATACGCTGCTGCGCATCATCGCCGCG
CAGACCGAGATCGCGAAGCTCGGCCTCGATCTCGGCAGCGTGATGGCCTATGTGGCCGAGCAGGTGCCGCAGCTCACCGG
CGCGAGCGCCGCCGCGGTCGAATTCGCCGAGGGCGACGACATGGTGTACCGCGCGGCGTCGGGCACCGCGGCCGGGATGC
TCGGCCTGCGGCTGCGGCGCTCGGGCAGCCTGTCGGGCCTGTGCGTGCAGCAAGGCGAGTTGCTGCACTGCATCGATTCG
GAAATCGACCCGCGCGTCGATCGCGACGCCTGCCGGCGGGTCGGCCTGCGCTCGATGCTCGTGATGCTGCTCACCCATGC
CGACACGACCGTCGGCGTGCTGAAGGTGATGTCGCCGGAAGTCGACGGCTTTTCGCAAGCCGACGCCGGCACGCTGCGGC
TGACGGCCGACCTGATCGCCGCCGCGATGTTCCACGCGGCGCGCAACGAAGCGAACGAGCTGTACCTGCGCGCGACGCAC
GACGCGCTCACCGGCCTGCCGAACCGCGCGCTGTTCTACGACCGCCTGCGGCAGTCGATGCACACGACGCTGCGCGCGAA
CGGCCGCCTCGGCATTCTCAACATCGACATGGACGGGCTGAAGCCGATCAACGATGGCCTCGGCCACCGTGCGGGCGACG
CGGCGCTGCGCGAGATCGCCTCGCGGATGCAGGGAGCGGTGCGGCGCTCGGACACGGTCGCGCGCATCGGCGGCGACGAA
TTCGCGGTGATCCTGCCGAACATCGGCAACCGCGACGATGCGCATGCGCAAAGCACGCGGCTCGCACACCAGGTCGGCGA
ACCGTTCGAATTCGAGGGGCGCCCGATGCGGCTCGGCGTCAGCGTCGGGATCGCGCTGCTGCCCGACGACGGCACCGACA
TGAACGCGCTGATCGAGCATGCGGACCAGGCGATGTATGAAGTGAAGCGCACGCGGTCGCAGCGGGTCGCTCAGGCGTAA

Upstream 100 bases:

>100_bases
CGTCACACTATCTCAAAAACAGGACAAAACTTACCCCGATTCGCGATGTTGAAGCGAAAAAAACCTCAATCCGGTCGGAA
ATGCTGCGCGAGCGAGATGA

Downstream 100 bases:

>100_bases
CGCGTACTCTCAGGCTGCTTCCTTGACGAGCCTGCGGGTGGAACGACACCCTCGACCGCCCGCAGCCGGCTCGACCGGGC
GCTAGCCGATCTGCGGAACG

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MVRIAPLSPGRPDGILPARCGWPAAVRCRPPRLNARPRGGAYATAIPSRRTCFLSRKTDLNQIVDTATPSPDTLLRIIAA
QTEIAKLGLDLGSVMAYVAEQVPQLTGASAAAVEFAEGDDMVYRAASGTAAGMLGLRLRRSGSLSGLCVQQGELLHCIDS
EIDPRVDRDACRRVGLRSMLVMLLTHADTTVGVLKVMSPEVDGFSQADAGTLRLTADLIAAAMFHAARNEANELYLRATH
DALTGLPNRALFYDRLRQSMHTTLRANGRLGILNIDMDGLKPINDGLGHRAGDAALREIASRMQGAVRRSDTVARIGGDE
FAVILPNIGNRDDAHAQSTRLAHQVGEPFEFEGRPMRLGVSVGIALLPDDGTDMNALIEHADQAMYEVKRTRSQRVAQA

Sequences:

>Translated_399_residues
MVRIAPLSPGRPDGILPARCGWPAAVRCRPPRLNARPRGGAYATAIPSRRTCFLSRKTDLNQIVDTATPSPDTLLRIIAA
QTEIAKLGLDLGSVMAYVAEQVPQLTGASAAAVEFAEGDDMVYRAASGTAAGMLGLRLRRSGSLSGLCVQQGELLHCIDS
EIDPRVDRDACRRVGLRSMLVMLLTHADTTVGVLKVMSPEVDGFSQADAGTLRLTADLIAAAMFHAARNEANELYLRATH
DALTGLPNRALFYDRLRQSMHTTLRANGRLGILNIDMDGLKPINDGLGHRAGDAALREIASRMQGAVRRSDTVARIGGDE
FAVILPNIGNRDDAHAQSTRLAHQVGEPFEFEGRPMRLGVSVGIALLPDDGTDMNALIEHADQAMYEVKRTRSQRVAQA
>Mature_399_residues
MVRIAPLSPGRPDGILPARCGWPAAVRCRPPRLNARPRGGAYATAIPSRRTCFLSRKTDLNQIVDTATPSPDTLLRIIAA
QTEIAKLGLDLGSVMAYVAEQVPQLTGASAAAVEFAEGDDMVYRAASGTAAGMLGLRLRRSGSLSGLCVQQGELLHCIDS
EIDPRVDRDACRRVGLRSMLVMLLTHADTTVGVLKVMSPEVDGFSQADAGTLRLTADLIAAAMFHAARNEANELYLRATH
DALTGLPNRALFYDRLRQSMHTTLRANGRLGILNIDMDGLKPINDGLGHRAGDAALREIASRMQGAVRRSDTVARIGGDE
FAVILPNIGNRDDAHAQSTRLAHQVGEPFEFEGRPMRLGVSVGIALLPDDGTDMNALIEHADQAMYEVKRTRSQRVAQA

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=164, Percent_Identity=41.4634146341463, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1787541, Length=162, Percent_Identity=33.9506172839506, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI87081977, Length=232, Percent_Identity=28.8793103448276, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1787802, Length=173, Percent_Identity=31.2138728323699, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI87081974, Length=155, Percent_Identity=30.9677419354839, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1786584, Length=167, Percent_Identity=31.7365269461078, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788956, Length=162, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87082007, Length=229, Percent_Identity=27.0742358078603, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI145693134, Length=162, Percent_Identity=32.7160493827161, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1787262, Length=190, Percent_Identity=27.8947368421053, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI87081881, Length=198, Percent_Identity=30.8080808080808, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1787816, Length=194, Percent_Identity=28.8659793814433, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1788085, Length=155, Percent_Identity=26.4516129032258, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 42956; Mature: 42956

Theoretical pI: Translated: 8.15; Mature: 8.15

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRIAPLSPGRPDGILPARCGWPAAVRCRPPRLNARPRGGAYATAIPSRRTCFLSRKTDL
CEEECCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCEEEEECCCCCEEEEECCCCH
NQIVDTATPSPDTLLRIIAAQTEIAKLGLDLGSVMAYVAEQVPQLTGASAAAVEFAEGDD
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHEEEECCCCC
MVYRAASGTAAGMLGLRLRRSGSLSGLCVQQGELLHCIDSEIDPRVDRDACRRVGLRSML
EEEEECCCCHHHHHHHEEECCCCCCCEEECCCCEEEECCCCCCCCCCHHHHHHHHHHHHH
VMLLTHADTTVGVLKVMSPEVDGFSQADAGTLRLTADLIAAAMFHAARNEANELYLRATH
HHHHHCCCCHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHCCCCEEEEEECH
DALTGLPNRALFYDRLRQSMHTTLRANGRLGILNIDMDGLKPINDGLGHRAGDAALREIA
HHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHCCCCCHHHHHHHHH
SRMQGAVRRSDTVARIGGDEFAVILPNIGNRDDAHAQSTRLAHQVGEPFEFEGRPMRLGV
HHHHHHHHHCCCEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEE
SVGIALLPDDGTDMNALIEHADQAMYEVKRTRSQRVAQA
EEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVRIAPLSPGRPDGILPARCGWPAAVRCRPPRLNARPRGGAYATAIPSRRTCFLSRKTDL
CEEECCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCEEEEECCCCCEEEEECCCCH
NQIVDTATPSPDTLLRIIAAQTEIAKLGLDLGSVMAYVAEQVPQLTGASAAAVEFAEGDD
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHEEEECCCCC
MVYRAASGTAAGMLGLRLRRSGSLSGLCVQQGELLHCIDSEIDPRVDRDACRRVGLRSML
EEEEECCCCHHHHHHHEEECCCCCCCEEECCCCEEEECCCCCCCCCCHHHHHHHHHHHHH
VMLLTHADTTVGVLKVMSPEVDGFSQADAGTLRLTADLIAAAMFHAARNEANELYLRATH
HHHHHCCCCHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHCCCCEEEEEECH
DALTGLPNRALFYDRLRQSMHTTLRANGRLGILNIDMDGLKPINDGLGHRAGDAALREIA
HHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHCCCCCHHHHHHHHH
SRMQGAVRRSDTVARIGGDEFAVILPNIGNRDDAHAQSTRLAHQVGEPFEFEGRPMRLGV
HHHHHHHHHCCCEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEE
SVGIALLPDDGTDMNALIEHADQAMYEVKRTRSQRVAQA
EEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]