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The map label for this gene is rstB [H]

Identifier: 78065964

GI number: 78065964

Start: 1459258

End: 1460634

Strand: Reverse

Name: rstB [H]

Synonym: Bcep18194_A4493

Alternate gene names: 78065964

Gene position: 1460634-1459258 (Counterclockwise)

Preceding gene: 78065965

Following gene: 78065957

Centisome position: 39.54

GC content: 66.88

Gene sequence:

>1377_bases
ATGCTCCGCCCGTTGATCCGGCTGTATCTCGTCGTCATCCTGTTCGTCGCCGCGTCGATCATCTTCATCCAGCTGTCGTT
CGACCGGATCTTCTACGATCGCAGCGCGCAGGCCGAGCGCGATTCGTTGACGACCTACGCGTTCGTGCTCAACGACTACC
TCGAACGCCATCCGGGCGAGCAGCGCAAGCTGGCGCTGCGCGAGCTCGCGAAACACGGCAACGAAAGGTTCGACTTCATG
CCGATGGCCACCGCCCGCGCGCAGTTGAGCGGCGAGCCGCTGCGCGATCTCGACGCCGGCCGGATCTCGATCAGCTACGA
CGGCAAGGATTACTACATGCCGCTCGCGGATGGTTCGGTCCTGCATGCGCGGCCGATCGAAGCATTCAGTCTCGACATCA
AGATCTATGCATACATGCTGCTCGCGCTCAGCACGCTGCTCGCGGTGGTGCTGTGGGTTCACTATCACTGGCGCGACCTG
CGCAGGCTGCAGGAAGCCGCACGCGCATTTGGCGCCGGCACGCTGTCGACGCGCGTGAAGCTGTCGGGCAAATCGAACAT
CTACGAGCTGTCGCAACAGTTCAACGACATGGCCGAGCGCATCGAGGCGTCGATCAAGCAGCAGCGCGAAATGATGCACG
GCATCTCGCACGAACTGAAGACACCGCTCGCGCGGCTCGAATTCGGGCTCGCGCTGCTCGCGGAGCCTGACGAAACGGGA
CGGATGCGCGAACGCCGCGATGCGCTGCGGCGCGACGTGCGCGAACTCGACGAGCTCGTCACCGAGCTGCTGACGATCGG
CCGGCTCGAACAGGGCGCGAGCCAGCTCGCGCCGATGGAAGTCGTCGTCGATGCGCTGATCGACAGCGTCGCCGGCAGCG
TCGCGAACGACATTGCCGATCGCGGCATCACGCTCGACGTGTCGGCGCTCGGAGCACCCGCGACCCACGTGTGCGACCCG
AAGCTGGTCGCCCGCGCGTTGCTGAACCTGATCCGCAACGGCGCGCGCTACGCATCGCGCACGGTGCTGCTCGCCGCCGA
GCGCACCGCGTCCGGCGCGCTCGTGCTGAGCGTCGACGACGATGGCCCCGGCATTCCGGCCGCCGAACGCGCGCGCGTGT
TCGAGCCGTTCCAGCGGCTCGACTCCAGCCGCGACCGGCAGACCGGCGGCTTCGGGCTCGGGCTTGCGATCGTGCGACGC
GTCGCGCTGGTGCACGGGGGCGACGTGCGGCTTGAGGATTCGCCGCTCGGCGGCGCACGCTTCGTGATCACGCTGCCCGC
GCTGGCGCTGCTGGACAATCTGTTCGATTTGCCGGATACCGTCACGAATCTCGACACGTTCGGCGGCAGCGCCGGCATGG
CCATCCCGCGGCAATGA

Upstream 100 bases:

>100_bases
GCTGCGCCGCCGCTTCGAGGATGCGTCGTCGGAGCCGCACAAGATCAAGACGATCTGGGGCCGCGGCTACCTGTTCAGCC
CTTCTGCGTGGGACGAATAA

Downstream 100 bases:

>100_bases
AGCGCGCGGCAGGACGCGCCCTGGCCGCCCTCGCCTGACCTGCGCGCCGCTCAGTGGCGGCGCAGCAGCGCGACGAAGAA
CAGGCTGCCGAACATCGCGG

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MLRPLIRLYLVVILFVAASIIFIQLSFDRIFYDRSAQAERDSLTTYAFVLNDYLERHPGEQRKLALRELAKHGNERFDFM
PMATARAQLSGEPLRDLDAGRISISYDGKDYYMPLADGSVLHARPIEAFSLDIKIYAYMLLALSTLLAVVLWVHYHWRDL
RRLQEAARAFGAGTLSTRVKLSGKSNIYELSQQFNDMAERIEASIKQQREMMHGISHELKTPLARLEFGLALLAEPDETG
RMRERRDALRRDVRELDELVTELLTIGRLEQGASQLAPMEVVVDALIDSVAGSVANDIADRGITLDVSALGAPATHVCDP
KLVARALLNLIRNGARYASRTVLLAAERTASGALVLSVDDDGPGIPAAERARVFEPFQRLDSSRDRQTGGFGLGLAIVRR
VALVHGGDVRLEDSPLGGARFVITLPALALLDNLFDLPDTVTNLDTFGGSAGMAIPRQ

Sequences:

>Translated_458_residues
MLRPLIRLYLVVILFVAASIIFIQLSFDRIFYDRSAQAERDSLTTYAFVLNDYLERHPGEQRKLALRELAKHGNERFDFM
PMATARAQLSGEPLRDLDAGRISISYDGKDYYMPLADGSVLHARPIEAFSLDIKIYAYMLLALSTLLAVVLWVHYHWRDL
RRLQEAARAFGAGTLSTRVKLSGKSNIYELSQQFNDMAERIEASIKQQREMMHGISHELKTPLARLEFGLALLAEPDETG
RMRERRDALRRDVRELDELVTELLTIGRLEQGASQLAPMEVVVDALIDSVAGSVANDIADRGITLDVSALGAPATHVCDP
KLVARALLNLIRNGARYASRTVLLAAERTASGALVLSVDDDGPGIPAAERARVFEPFQRLDSSRDRQTGGFGLGLAIVRR
VALVHGGDVRLEDSPLGGARFVITLPALALLDNLFDLPDTVTNLDTFGGSAGMAIPRQ
>Mature_458_residues
MLRPLIRLYLVVILFVAASIIFIQLSFDRIFYDRSAQAERDSLTTYAFVLNDYLERHPGEQRKLALRELAKHGNERFDFM
PMATARAQLSGEPLRDLDAGRISISYDGKDYYMPLADGSVLHARPIEAFSLDIKIYAYMLLALSTLLAVVLWVHYHWRDL
RRLQEAARAFGAGTLSTRVKLSGKSNIYELSQQFNDMAERIEASIKQQREMMHGISHELKTPLARLEFGLALLAEPDETG
RMRERRDALRRDVRELDELVTELLTIGRLEQGASQLAPMEVVVDALIDSVAGSVANDIADRGITLDVSALGAPATHVCDP
KLVARALLNLIRNGARYASRTVLLAAERTASGALVLSVDDDGPGIPAAERARVFEPFQRLDSSRDRQTGGFGLGLAIVRR
VALVHGGDVRLEDSPLGGARFVITLPALALLDNLFDLPDTVTNLDTFGGSAGMAIPRQ

Specific function: Member of the two-component regulatory system rstB/rstA. RstB functions as a membrane-associated protein kinase that phosphorylates rstA (Potential) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787894, Length=300, Percent_Identity=37.6666666666667, Blast_Score=186, Evalue=4e-48,
Organism=Escherichia coli, GI1790346, Length=267, Percent_Identity=34.4569288389513, Blast_Score=148, Evalue=6e-37,
Organism=Escherichia coli, GI1789808, Length=292, Percent_Identity=29.7945205479452, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788393, Length=271, Percent_Identity=30.6273062730627, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1786783, Length=339, Percent_Identity=29.2035398230088, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI1786600, Length=229, Percent_Identity=29.2576419213974, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1786912, Length=237, Percent_Identity=30.8016877637131, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI87082128, Length=297, Percent_Identity=28.2828282828283, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1789149, Length=230, Percent_Identity=26.0869565217391, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788713, Length=285, Percent_Identity=25.6140350877193, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI145693157, Length=253, Percent_Identity=22.9249011857708, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790551, Length=260, Percent_Identity=27.3076923076923, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI87081816, Length=337, Percent_Identity=23.7388724035608, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1790861, Length=320, Percent_Identity=28.75, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1787374, Length=329, Percent_Identity=24.9240121580547, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1790436, Length=215, Percent_Identity=26.9767441860465, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788549, Length=221, Percent_Identity=23.9819004524887, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI48994928, Length=257, Percent_Identity=24.5136186770428, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50648; Mature: 50648

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRPLIRLYLVVILFVAASIIFIQLSFDRIFYDRSAQAERDSLTTYAFVLNDYLERHPGE
CCHHHHHHHHHHHHHHHHHHHHHEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCH
QRKLALRELAKHGNERFDFMPMATARAQLSGEPLRDLDAGRISISYDGKDYYMPLADGSV
HHHHHHHHHHHCCCCCEEEEEHHHHHHHCCCCCCCCCCCCEEEEEECCCEEEEECCCCCE
LHARPIEAFSLDIKIYAYMLLALSTLLAVVLWVHYHWRDLRRLQEAARAFGAGTLSTRVK
EECCCCHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
LSGKSNIYELSQQFNDMAERIEASIKQQREMMHGISHELKTPLARLEFGLALLAEPDETG
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEECCCCCH
RMRERRDALRRDVRELDELVTELLTIGRLEQGASQLAPMEVVVDALIDSVAGSVANDIAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
RGITLDVSALGAPATHVCDPKLVARALLNLIRNGARYASRTVLLAAERTASGALVLSVDD
CCCEEEEHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHCEEEEEEECCCCCEEEEEECC
DGPGIPAAERARVFEPFQRLDSSRDRQTGGFGLGLAIVRRVALVHGGDVRLEDSPLGGAR
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCC
FVITLPALALLDNLFDLPDTVTNLDTFGGSAGMAIPRQ
HHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MLRPLIRLYLVVILFVAASIIFIQLSFDRIFYDRSAQAERDSLTTYAFVLNDYLERHPGE
CCHHHHHHHHHHHHHHHHHHHHHEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCH
QRKLALRELAKHGNERFDFMPMATARAQLSGEPLRDLDAGRISISYDGKDYYMPLADGSV
HHHHHHHHHHHCCCCCEEEEEHHHHHHHCCCCCCCCCCCCEEEEEECCCEEEEECCCCCE
LHARPIEAFSLDIKIYAYMLLALSTLLAVVLWVHYHWRDLRRLQEAARAFGAGTLSTRVK
EECCCCHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
LSGKSNIYELSQQFNDMAERIEASIKQQREMMHGISHELKTPLARLEFGLALLAEPDETG
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEECCCCCH
RMRERRDALRRDVRELDELVTELLTIGRLEQGASQLAPMEVVVDALIDSVAGSVANDIAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
RGITLDVSALGAPATHVCDPKLVARALLNLIRNGARYASRTVLLAAERTASGALVLSVDD
CCCEEEEHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHCEEEEEEECCCCCEEEEEECC
DGPGIPAAERARVFEPFQRLDSSRDRQTGGFGLGLAIVRRVALVHGGDVRLEDSPLGGAR
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCC
FVITLPALALLDNLFDLPDTVTNLDTFGGSAGMAIPRQ
HHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 2646639; 1925016; 1495392 [H]