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The map label for this gene is fadH [H]

Identifier: 78065948

GI number: 78065948

Start: 1440677

End: 1442701

Strand: Direct

Name: fadH [H]

Synonym: Bcep18194_A4477

Alternate gene names: 78065948

Gene position: 1440677-1442701 (Clockwise)

Preceding gene: 78065945

Following gene: 78065949

Centisome position: 39.0

GC content: 67.16

Gene sequence:

>2025_bases
ATGACATCGCGTTATCCGCATCTGACGACCCCGCTCGAGCTCGGCTTCACGTCGCTCAGGAATCGAGTGCTGATGGGGTC
GATGCACGTCGGTCTCGAGGAAGCGCCGAACGGCTTCGAGCGGATGGCGGCGTTCTATGCCGAGCGCGCGCGCGGCGAAG
CCGGCCTGATCGTGACGGGCGGATTCGCGCCGAACGAGCGCGGCCGTCCGGCGCCGGGCGGTGCGATGCTGACGACCGAA
GCGGAAGCCGAGCGTCATCGTGTCGTGACGCGCGCGGTGCACGCGGAGGGCGGCAAGATCGCGCTGCAGATCCTGCATTT
CGGGCGCTACGCGTATCACCCGGCGCTCGCCGCGCCGAGCGCGCTGAAGGCGCCGATCAACCCGTTCACGCCGCATGCGC
TGAGCAGCGATGAAGTCGACGAGACGATCGCCGATTTCGTGCGATGCGCGGCGCTCGCGCAGCATGCGGGTTACGACGGT
GTCGAGATCATGGGGTCGGAGGGCTACCTGATCAACGAATTCATCGCCGCGCGGACGAACCATCGCGACGACGCATGGGG
CGGTGCCTACGAGAACCGTATCCGCTTTCCGGTCGAGATCGTGCGGCGCGTGCGCGAGCGGGTCGGCACGAACTTCATCC
TGATCTACCGCCTGTCGATGCTCGATCTCGTCGAAGGCGGCTCGACGCTCGACGAAGTGATCCGGCTCGCACAGGCGATC
GAAGCGGCCGGTGCAACGATCATCAATACGGGTATCGGCTGGCACGAGGCGCGCATTCCGACCATCGCGACGAAGGTGCC
GCGCGCCGCGTACGCGTGGGTCACGCGGCAGTTGATGGGCCAGGTCGGCATCCCGCTCGTCGCGACCAACCGGATCAACA
CGCCGGAAGTCGCCGAGCAACTGCTCGCCGACGGCTATTGCGACATGGTGTCGATGGCGCGGCCGTTCCTCGCCGATGCC
GAGTTCGTCCGCAAGGCGCGGGAAGGGCGCGCGGACGAAATCAACACGTGCATCGGCTGTAACCAGGCCTGCCTCGACCA
TACGTTCAGCGGCAGGATCACGTCGTGTCTCGTGAATCCGCGCGCGTGCCATGAAACCGAGCTCGTGATTCGCCCGGCGC
AGCAGCGCAAGCGGATCGCCGTGGTCGGCGCCGGGCCGGCGGGCCTCGGCTTCGCGGTCACCGCGGCCGAGCGCGGCCAT
GCGGTGACGCTGTACGAAGCCGGCGCGGAGATCGGCGGCCAGTTCAACATCGCGAAGAAGGTGCCCGGCAAGGAAGAATT
CAACGAGACGCTGCGCTATTTCCGCCGGCAGATCGAACTGCGCGGCGTGACGCTTCACCTCAATACGCGCGCGACCGCCG
AGATGCTGGTGCAAGGCGAATTCGATGAAGTGGTGATCGCGACGGGCATCGTGCCGCGTACGCCGCCGATCGATGGTGTC
GGGCACGCGAAGACGCTCGGCTACCTCGACGTGTTGCGCGACGACCAGGCCGTGGGCAGCCGCGTTGCGATCGTCGGCGC
TGGCGGGATCGGCTTCGACGTCGCGGAATATCTCGTCCATCGCGCGGGTGCCGAGCACGTCGACGCGGAACGGTTCTTCA
CCGAGTGGGGTGTCGATCCGTCATATGCGAACGCAGGCGGTTTGCGCCACGCGCAGCCCGAGCCGGCCGCACGGCAAATC
CATCTGCTGCAGCGCAAAGCGTCGAAGGTCGGCGACGGGCTCGGCAAGACCACCGGCTGGATTCACCGCACGGGGCTGAA
GGCGCGCGGCGTCGGGATGTCGTCGGCGGTGACCTATCGGCGCATCGACGACGACGGATTCCACGTGACGATCGACGGCG
TCGAACAGACGCTGCCGGTGGACAACGTCGTGATCTGCGCGGGACAGGAGCCGTTGCGCGAACTGGCGGAGCAACTGGAA
GCCGCCGGGCGCAAGGTGCACGTGATCGGTGGCGCGTACGAAGCGGCCGAGCTCGATGCGAAACGCGCGATTCACCAGGG
CACGTCGCTTGCCGCCACCCTTTGA

Upstream 100 bases:

>100_bases
CACAGTACAAGGTGATGGATGTGTTTATGCAACGGGTTGCATAAACGAGAGTGGTGGACTACCATCTGTGCAACTTGTTG
CATAAAAATGGAGACACCCC

Downstream 100 bases:

>100_bases
GAGTTGAGACCGATTCGTTTCTTTTCCGCCCGACGATACAGGAGTCTTCGATGACGAACGCAGCGCTGCATCTTCAACCC
GCTGTCGCGCAATCGCTCGA

Product: 2,4-dienoyl-CoA reductase

Products: NA

Alternate protein names: 2,4-dienoyl coenzyme A reductase [H]

Number of amino acids: Translated: 674; Mature: 673

Protein sequence:

>674_residues
MTSRYPHLTTPLELGFTSLRNRVLMGSMHVGLEEAPNGFERMAAFYAERARGEAGLIVTGGFAPNERGRPAPGGAMLTTE
AEAERHRVVTRAVHAEGGKIALQILHFGRYAYHPALAAPSALKAPINPFTPHALSSDEVDETIADFVRCAALAQHAGYDG
VEIMGSEGYLINEFIAARTNHRDDAWGGAYENRIRFPVEIVRRVRERVGTNFILIYRLSMLDLVEGGSTLDEVIRLAQAI
EAAGATIINTGIGWHEARIPTIATKVPRAAYAWVTRQLMGQVGIPLVATNRINTPEVAEQLLADGYCDMVSMARPFLADA
EFVRKAREGRADEINTCIGCNQACLDHTFSGRITSCLVNPRACHETELVIRPAQQRKRIAVVGAGPAGLGFAVTAAERGH
AVTLYEAGAEIGGQFNIAKKVPGKEEFNETLRYFRRQIELRGVTLHLNTRATAEMLVQGEFDEVVIATGIVPRTPPIDGV
GHAKTLGYLDVLRDDQAVGSRVAIVGAGGIGFDVAEYLVHRAGAEHVDAERFFTEWGVDPSYANAGGLRHAQPEPAARQI
HLLQRKASKVGDGLGKTTGWIHRTGLKARGVGMSSAVTYRRIDDDGFHVTIDGVEQTLPVDNVVICAGQEPLRELAEQLE
AAGRKVHVIGGAYEAAELDAKRAIHQGTSLAATL

Sequences:

>Translated_674_residues
MTSRYPHLTTPLELGFTSLRNRVLMGSMHVGLEEAPNGFERMAAFYAERARGEAGLIVTGGFAPNERGRPAPGGAMLTTE
AEAERHRVVTRAVHAEGGKIALQILHFGRYAYHPALAAPSALKAPINPFTPHALSSDEVDETIADFVRCAALAQHAGYDG
VEIMGSEGYLINEFIAARTNHRDDAWGGAYENRIRFPVEIVRRVRERVGTNFILIYRLSMLDLVEGGSTLDEVIRLAQAI
EAAGATIINTGIGWHEARIPTIATKVPRAAYAWVTRQLMGQVGIPLVATNRINTPEVAEQLLADGYCDMVSMARPFLADA
EFVRKAREGRADEINTCIGCNQACLDHTFSGRITSCLVNPRACHETELVIRPAQQRKRIAVVGAGPAGLGFAVTAAERGH
AVTLYEAGAEIGGQFNIAKKVPGKEEFNETLRYFRRQIELRGVTLHLNTRATAEMLVQGEFDEVVIATGIVPRTPPIDGV
GHAKTLGYLDVLRDDQAVGSRVAIVGAGGIGFDVAEYLVHRAGAEHVDAERFFTEWGVDPSYANAGGLRHAQPEPAARQI
HLLQRKASKVGDGLGKTTGWIHRTGLKARGVGMSSAVTYRRIDDDGFHVTIDGVEQTLPVDNVVICAGQEPLRELAEQLE
AAGRKVHVIGGAYEAAELDAKRAIHQGTSLAATL
>Mature_673_residues
TSRYPHLTTPLELGFTSLRNRVLMGSMHVGLEEAPNGFERMAAFYAERARGEAGLIVTGGFAPNERGRPAPGGAMLTTEA
EAERHRVVTRAVHAEGGKIALQILHFGRYAYHPALAAPSALKAPINPFTPHALSSDEVDETIADFVRCAALAQHAGYDGV
EIMGSEGYLINEFIAARTNHRDDAWGGAYENRIRFPVEIVRRVRERVGTNFILIYRLSMLDLVEGGSTLDEVIRLAQAIE
AAGATIINTGIGWHEARIPTIATKVPRAAYAWVTRQLMGQVGIPLVATNRINTPEVAEQLLADGYCDMVSMARPFLADAE
FVRKAREGRADEINTCIGCNQACLDHTFSGRITSCLVNPRACHETELVIRPAQQRKRIAVVGAGPAGLGFAVTAAERGHA
VTLYEAGAEIGGQFNIAKKVPGKEEFNETLRYFRRQIELRGVTLHLNTRATAEMLVQGEFDEVVIATGIVPRTPPIDGVG
HAKTLGYLDVLRDDQAVGSRVAIVGAGGIGFDVAEYLVHRAGAEHVDAERFFTEWGVDPSYANAGGLRHAQPEPAARQIH
LLQRKASKVGDGLGKTTGWIHRTGLKARGVGMSSAVTYRRIDDDGFHVTIDGVEQTLPVDNVVICAGQEPLRELAEQLEA
AGRKVHVIGGAYEAAELDAKRAIHQGTSLAATL

Specific function: Catalyzes the NADP-dependent reduction of 2,4-dienoyl- CoA to yield trans-2- enoyl-CoA [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789463, Length=669, Percent_Identity=65.7698056801196, Blast_Score=892, Evalue=0.0,
Organism=Escherichia coli, GI1787939, Length=352, Percent_Identity=28.4090909090909, Blast_Score=99, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17540738, Length=224, Percent_Identity=25.8928571428571, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17559802, Length=317, Percent_Identity=24.2902208201893, Blast_Score=92, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17564188, Length=308, Percent_Identity=23.7012987012987, Blast_Score=90, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17559804, Length=368, Percent_Identity=23.9130434782609, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17565138, Length=230, Percent_Identity=27.3913043478261, Blast_Score=89, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17566914, Length=315, Percent_Identity=26.031746031746, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI72001454, Length=228, Percent_Identity=25.8771929824561, Blast_Score=79, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6321973, Length=225, Percent_Identity=27.1111111111111, Blast_Score=84, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6325086, Length=235, Percent_Identity=28.5106382978723, Blast_Score=81, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013027
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN; PF07992 Pyr_redox_2 [H]

EC number: =1.3.1.34 [H]

Molecular weight: Translated: 72878; Mature: 72747

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSRYPHLTTPLELGFTSLRNRVLMGSMHVGLEEAPNGFERMAAFYAERARGEAGLIVTG
CCCCCCCCCCHHHHHHHHHHCCEEECHHHCCHHHCCCHHHHHHHHHHHHHCCCCCEEEEC
GFAPNERGRPAPGGAMLTTEAEAERHRVVTRAVHAEGGKIALQILHFGRYAYHPALAAPS
CCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHCHHHCCCH
ALKAPINPFTPHALSSDEVDETIADFVRCAALAQHAGYDGVEIMGSEGYLINEFIAARTN
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHCC
HRDDAWGGAYENRIRFPVEIVRRVRERVGTNFILIYRLSMLDLVEGGSTLDEVIRLAQAI
CCCCCCCCCHHCCCCCHHHHHHHHHHHHCCCEEEEEHHHHHHHHCCCCHHHHHHHHHHHH
EAAGATIINTGIGWHEARIPTIATKVPRAAYAWVTRQLMGQVGIPLVATNRINTPEVAEQ
HHCCCEEEECCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHH
LLADGYCDMVSMARPFLADAEFVRKAREGRADEINTCIGCNQACLDHTFSGRITSCLVNP
HHHCCHHHHHHHHCHHHCCHHHHHHHHCCCCHHHHHHHCCCHHHHCCCCCCCHHHEEECC
RACHETELVIRPAQQRKRIAVVGAGPAGLGFAVTAAERGHAVTLYEAGAEIGGQFNIAKK
CCCCCCCEEECCCCCCCEEEEEECCCCCCCEEEEECCCCCEEEEEECCHHCCCCEEECCC
VPGKEEFNETLRYFRRQIELRGVTLHLNTRATAEMLVQGEFDEVVIATGIVPRTPPIDGV
CCCHHHHHHHHHHHHHHHEEEEEEEEECCCCHHHHHCCCCCCCEEEEECCCCCCCCCCCC
GHAKTLGYLDVLRDDQAVGSRVAIVGAGGIGFDVAEYLVHRAGAEHVDAERFFTEWGVDP
CCHHHHHHHHHHCCCHHCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHCCCCC
SYANAGGLRHAQPEPAARQIHLLQRKASKVGDGLGKTTGWIHRTGLKARGVGMSSAVTYR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCCCEEEE
RIDDDGFHVTIDGVEQTLPVDNVVICAGQEPLRELAEQLEAAGRKVHVIGGAYEAAELDA
EECCCCCEEEECCCHHHCCCCCEEEECCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHH
KRAIHQGTSLAATL
HHHHHCCCCCEECC
>Mature Secondary Structure 
TSRYPHLTTPLELGFTSLRNRVLMGSMHVGLEEAPNGFERMAAFYAERARGEAGLIVTG
CCCCCCCCCHHHHHHHHHHCCEEECHHHCCHHHCCCHHHHHHHHHHHHHCCCCCEEEEC
GFAPNERGRPAPGGAMLTTEAEAERHRVVTRAVHAEGGKIALQILHFGRYAYHPALAAPS
CCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHCHHHCCCH
ALKAPINPFTPHALSSDEVDETIADFVRCAALAQHAGYDGVEIMGSEGYLINEFIAARTN
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHCC
HRDDAWGGAYENRIRFPVEIVRRVRERVGTNFILIYRLSMLDLVEGGSTLDEVIRLAQAI
CCCCCCCCCHHCCCCCHHHHHHHHHHHHCCCEEEEEHHHHHHHHCCCCHHHHHHHHHHHH
EAAGATIINTGIGWHEARIPTIATKVPRAAYAWVTRQLMGQVGIPLVATNRINTPEVAEQ
HHCCCEEEECCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHH
LLADGYCDMVSMARPFLADAEFVRKAREGRADEINTCIGCNQACLDHTFSGRITSCLVNP
HHHCCHHHHHHHHCHHHCCHHHHHHHHCCCCHHHHHHHCCCHHHHCCCCCCCHHHEEECC
RACHETELVIRPAQQRKRIAVVGAGPAGLGFAVTAAERGHAVTLYEAGAEIGGQFNIAKK
CCCCCCCEEECCCCCCCEEEEEECCCCCCCEEEEECCCCCEEEEEECCHHCCCCEEECCC
VPGKEEFNETLRYFRRQIELRGVTLHLNTRATAEMLVQGEFDEVVIATGIVPRTPPIDGV
CCCHHHHHHHHHHHHHHHEEEEEEEEECCCCHHHHHCCCCCCCEEEEECCCCCCCCCCCC
GHAKTLGYLDVLRDDQAVGSRVAIVGAGGIGFDVAEYLVHRAGAEHVDAERFFTEWGVDP
CCHHHHHHHHHHCCCHHCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHCCCCC
SYANAGGLRHAQPEPAARQIHLLQRKASKVGDGLGKTTGWIHRTGLKARGVGMSSAVTYR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCCCEEEE
RIDDDGFHVTIDGVEQTLPVDNVVICAGQEPLRELAEQLEAAGRKVHVIGGAYEAAELDA
EECCCCCEEEECCCHHHCCCCCEEEECCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHH
KRAIHQGTSLAATL
HHHHHCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9346310; 9278503 [H]