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The map label for this gene is bcd [H]

Identifier: 78065944

GI number: 78065944

Start: 1436301

End: 1438130

Strand: Direct

Name: bcd [H]

Synonym: Bcep18194_A4473

Alternate gene names: 78065944

Gene position: 1436301-1438130 (Clockwise)

Preceding gene: 78065943

Following gene: 78065945

Centisome position: 38.88

GC content: 67.76

Gene sequence:

>1830_bases
ATGAGCTTGTTGATGTCGCGACGCGATCTCGCGTTCCTGCTGTATGACTGGCTCGACGCGGAAGCGCTTGCCGCGCTGCC
GCGTTACACCGAGCACAGTCGCGAGACGTTCGACGCGGTGCTCGATACCAGCGAGCGGATTGCCGAAGACCTGTTCGCGC
CGCATGCGGCGCGTGGCGATCGCGAAGAGCCGCAGTTCGACGGCGAGCGCGTGACGCTGATCCCGGACGTCGAGCCGGCT
GTGCGCGCCTTTGCGGACGCCGGGCTGATCGCCGCGGGCCATGACGAAGCGCTCGGCGGCATGCGCTTGCCGAAGCTGGT
CGAAGCCGCGTCGTTCCTGTTCTTCCAGGCTGCGAACATCGCAACGGCCGCCTATCCGTTCCTGACCGTCGCCAATGCGA
ACCTGCTGGTCGCGCACGGCAGCCCGGCGCAGATTGACGCGTTCGCACGTCCGGAACTGGAGGGGCGCTACCTCGGCACC
ATGTGCCTGTCCGAGCCGCAAGCCGGGTCGTCGCTGTCCGACATCGCGACACGTGCGGATTTCGAAGGCGACTCGCCGCT
CGGCCCGCGCTACCGGCTGACGGGCAACAAGATGTGGATTTCGGGCGGTGAGCACGAGCTGACGGAGAACATCATCCACC
TCGTGCTCGCGAAGATTCCCGACGAACACGGCCGGCTGCTGCCCGGCACGCGCGGCATTTCGCTGTTCATCGTGCCCAAG
TACCTGCCGGGCGCCGACGGCGCGGCGCAGGGCGAGCACAACGACGTGGTGCTCGCCGGGCTGAACCACAAGATGGGTTA
CCGCGGCACCACCAACTGCCTGCTGAACTTCGGCGAAGGCACGCGCTACCGCCCGGAAGGGCGCGCAGGCGCGATCGGCT
ATCTCGTCGGCCAGGCGAACCACGGCCTCGCATACATGTTCCACATGATGAACGAAGCGCGTATCGGTGTCGGCGCGGGC
GCGGTGGCGCTCGGCTACACGGGTTATCTGCACGCGCTCGACTACGCGCGCAACCGGCCGCAAGGGCGCCCGCTGGGCCC
GGCGGGCAAGGATGCCGCCGCGCCGCAGGCGCCGATCGTCGAACATCCGGACGTGCGGCGCATGCTGCTCGCGCAGAAGT
CGTATGTCGAAGGCGGTCTCGCGCTGATCTTGTACTGCGCGAAGCTGGTCGATGAAGCACGCGCGCACGACGACGCGGAC
GTGCGTGCCCATGCCACGCGACTGCTCGACATCCTGACACCGATCACGAAAAGCTGGCCGTCGCAGTGGTGCCTCGCTGC
GAACGACCTCGCGATCCAGGTGCACGGCGGCTATGGCTACACGCGCGACTACGCGGTCGAGCGGCTCTATCGCGACAATC
GTCTCAATCCGATTCACGAAGGCACGCACGGGATTCAGGCGCTCGACCTGCTGGGCCGCAAGGTCGCCCAGGACGATGGC
GCGTTGCTGCACGCGCTCGATGCGCGGATCGGCGCGACCGTCGAACGTGCACGCGCGCTCGATGCCGGCCTGCGCGAACA
GGCCGATGCGCTGGCGCCGCGCTGGGCGCGGCTGGTCGAGGTCACACGGCAACTCGGCACGATCGGCGATCCGCAGGCGC
GGCTCGCGAACGCGAGCGTCTACCTGGAAGCGTTCGGCCATCTCGTCGTCGCGTGGCTGTGGCTCGACGTCACGCTCGCC
GCGCACGGGCAAGCCGACGATTTCCACGACGGCAAGCGTGCGGCGGCCCGCTATTTCTTCAACTGGGAATTGCCGAAAGT
GGATGCGCAGCTCGATCTGCTCGCGCGCGTCGACACGACGACGCTCGACATGCGCGACGCGTGGTTCTGA

Upstream 100 bases:

>100_bases
GTCGTTGTCGTTTTAGAACGACCGTGCTAAATTCCCGCCAGCACTAGCGGTCACGGAACCCTTCATTCGGCTGACGAAGC
CGGCCCCGGGAGGCAGCACG

Downstream 100 bases:

>100_bases
TCATTGCTTCACCGACATTCCGGAATGCAGACGATGTCGCGGTTGCCGATTCCGTCGGCTGTTGCGTCATCGTCGCGAAC
CGGCCGTGCGGGCGTGCCCC

Product: Acyl-CoA dehydrogenase

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 609; Mature: 608

Protein sequence:

>609_residues
MSLLMSRRDLAFLLYDWLDAEALAALPRYTEHSRETFDAVLDTSERIAEDLFAPHAARGDREEPQFDGERVTLIPDVEPA
VRAFADAGLIAAGHDEALGGMRLPKLVEAASFLFFQAANIATAAYPFLTVANANLLVAHGSPAQIDAFARPELEGRYLGT
MCLSEPQAGSSLSDIATRADFEGDSPLGPRYRLTGNKMWISGGEHELTENIIHLVLAKIPDEHGRLLPGTRGISLFIVPK
YLPGADGAAQGEHNDVVLAGLNHKMGYRGTTNCLLNFGEGTRYRPEGRAGAIGYLVGQANHGLAYMFHMMNEARIGVGAG
AVALGYTGYLHALDYARNRPQGRPLGPAGKDAAAPQAPIVEHPDVRRMLLAQKSYVEGGLALILYCAKLVDEARAHDDAD
VRAHATRLLDILTPITKSWPSQWCLAANDLAIQVHGGYGYTRDYAVERLYRDNRLNPIHEGTHGIQALDLLGRKVAQDDG
ALLHALDARIGATVERARALDAGLREQADALAPRWARLVEVTRQLGTIGDPQARLANASVYLEAFGHLVVAWLWLDVTLA
AHGQADDFHDGKRAAARYFFNWELPKVDAQLDLLARVDTTTLDMRDAWF

Sequences:

>Translated_609_residues
MSLLMSRRDLAFLLYDWLDAEALAALPRYTEHSRETFDAVLDTSERIAEDLFAPHAARGDREEPQFDGERVTLIPDVEPA
VRAFADAGLIAAGHDEALGGMRLPKLVEAASFLFFQAANIATAAYPFLTVANANLLVAHGSPAQIDAFARPELEGRYLGT
MCLSEPQAGSSLSDIATRADFEGDSPLGPRYRLTGNKMWISGGEHELTENIIHLVLAKIPDEHGRLLPGTRGISLFIVPK
YLPGADGAAQGEHNDVVLAGLNHKMGYRGTTNCLLNFGEGTRYRPEGRAGAIGYLVGQANHGLAYMFHMMNEARIGVGAG
AVALGYTGYLHALDYARNRPQGRPLGPAGKDAAAPQAPIVEHPDVRRMLLAQKSYVEGGLALILYCAKLVDEARAHDDAD
VRAHATRLLDILTPITKSWPSQWCLAANDLAIQVHGGYGYTRDYAVERLYRDNRLNPIHEGTHGIQALDLLGRKVAQDDG
ALLHALDARIGATVERARALDAGLREQADALAPRWARLVEVTRQLGTIGDPQARLANASVYLEAFGHLVVAWLWLDVTLA
AHGQADDFHDGKRAAARYFFNWELPKVDAQLDLLARVDTTTLDMRDAWF
>Mature_608_residues
SLLMSRRDLAFLLYDWLDAEALAALPRYTEHSRETFDAVLDTSERIAEDLFAPHAARGDREEPQFDGERVTLIPDVEPAV
RAFADAGLIAAGHDEALGGMRLPKLVEAASFLFFQAANIATAAYPFLTVANANLLVAHGSPAQIDAFARPELEGRYLGTM
CLSEPQAGSSLSDIATRADFEGDSPLGPRYRLTGNKMWISGGEHELTENIIHLVLAKIPDEHGRLLPGTRGISLFIVPKY
LPGADGAAQGEHNDVVLAGLNHKMGYRGTTNCLLNFGEGTRYRPEGRAGAIGYLVGQANHGLAYMFHMMNEARIGVGAGA
VALGYTGYLHALDYARNRPQGRPLGPAGKDAAAPQAPIVEHPDVRRMLLAQKSYVEGGLALILYCAKLVDEARAHDDADV
RAHATRLLDILTPITKSWPSQWCLAANDLAIQVHGGYGYTRDYAVERLYRDNRLNPIHEGTHGIQALDLLGRKVAQDDGA
LLHALDARIGATVERARALDAGLREQADALAPRWARLVEVTRQLGTIGDPQARLANASVYLEAFGHLVVAWLWLDVTLAA
HGQADDFHDGKRAAARYFFNWELPKVDAQLDLLARVDTTTLDMRDAWF

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=403, Percent_Identity=27.0471464019851, Blast_Score=104, Evalue=3e-22,
Organism=Homo sapiens, GI4557233, Length=448, Percent_Identity=27.6785714285714, Blast_Score=97, Evalue=7e-20,
Organism=Homo sapiens, GI7656849, Length=382, Percent_Identity=24.3455497382199, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI4501857, Length=394, Percent_Identity=25.6345177664975, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI226958412, Length=362, Percent_Identity=25.1381215469613, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI226958414, Length=362, Percent_Identity=25.1381215469613, Blast_Score=80, Evalue=6e-15,
Organism=Escherichia coli, GI87082384, Length=450, Percent_Identity=25.1111111111111, Blast_Score=89, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17538396, Length=447, Percent_Identity=25.503355704698, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI71990804, Length=207, Percent_Identity=28.0193236714976, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI21356377, Length=475, Percent_Identity=25.0526315789474, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24666513, Length=437, Percent_Identity=24.4851258581236, Blast_Score=94, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24646207, Length=441, Percent_Identity=25.8503401360544, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI21355753, Length=370, Percent_Identity=27.027027027027, Blast_Score=77, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 66448; Mature: 66317

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS00073 ACYL_COA_DH_2 ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLMSRRDLAFLLYDWLDAEALAALPRYTEHSRETFDAVLDTSERIAEDLFAPHAARGD
CCCCCCCCCHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCC
REEPQFDGERVTLIPDVEPAVRAFADAGLIAAGHDEALGGMRLPKLVEAASFLFFQAANI
CCCCCCCCCEEEEECCCCHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHH
ATAAYPFLTVANANLLVAHGSPAQIDAFARPELEGRYLGTMCLSEPQAGSSLSDIATRAD
HHHHCCEEEEECCCEEEECCCCCCCCCCCCCCCCCCEEEHHCCCCCCCCCCHHHHHHHCC
FEGDSPLGPRYRLTGNKMWISGGEHELTENIIHLVLAKIPDEHGRLLPGTRGISLFIVPK
CCCCCCCCCCEEEECCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEC
YLPGADGAAQGEHNDVVLAGLNHKMGYRGTTNCLLNFGEGTRYRPEGRAGAIGYLVGQAN
CCCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHEEECCCCCCCCCCCCCCEEEEEEECCC
HGLAYMFHMMNEARIGVGAGAVALGYTGYLHALDYARNRPQGRPLGPAGKDAAAPQAPIV
CCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
EHPDVRRMLLAQKSYVEGGLALILYCAKLVDEARAHDDADVRAHATRLLDILTPITKSWP
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCC
SQWCLAANDLAIQVHGGYGYTRDYAVERLYRDNRLNPIHEGTHGIQALDLLGRKVAQDDG
CCCEEEECCEEEEEECCCCCHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHHHHHCCCCC
ALLHALDARIGATVERARALDAGLREQADALAPRWARLVEVTRQLGTIGDPQARLANASV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
YLEAFGHLVVAWLWLDVTLAAHGQADDFHDGKRAAARYFFNWELPKVDAQLDLLARVDTT
HHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHEEEEECCCCCCCCHHHHHHHCCCC
TLDMRDAWF
EECCCCCCC
>Mature Secondary Structure 
SLLMSRRDLAFLLYDWLDAEALAALPRYTEHSRETFDAVLDTSERIAEDLFAPHAARGD
CCCCCCCCHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCC
REEPQFDGERVTLIPDVEPAVRAFADAGLIAAGHDEALGGMRLPKLVEAASFLFFQAANI
CCCCCCCCCEEEEECCCCHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHH
ATAAYPFLTVANANLLVAHGSPAQIDAFARPELEGRYLGTMCLSEPQAGSSLSDIATRAD
HHHHCCEEEEECCCEEEECCCCCCCCCCCCCCCCCCEEEHHCCCCCCCCCCHHHHHHHCC
FEGDSPLGPRYRLTGNKMWISGGEHELTENIIHLVLAKIPDEHGRLLPGTRGISLFIVPK
CCCCCCCCCCEEEECCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEC
YLPGADGAAQGEHNDVVLAGLNHKMGYRGTTNCLLNFGEGTRYRPEGRAGAIGYLVGQAN
CCCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHEEECCCCCCCCCCCCCCEEEEEEECCC
HGLAYMFHMMNEARIGVGAGAVALGYTGYLHALDYARNRPQGRPLGPAGKDAAAPQAPIV
CCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
EHPDVRRMLLAQKSYVEGGLALILYCAKLVDEARAHDDADVRAHATRLLDILTPITKSWP
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCC
SQWCLAANDLAIQVHGGYGYTRDYAVERLYRDNRLNPIHEGTHGIQALDLLGRKVAQDDG
CCCEEEECCEEEEEECCCCCHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHHHHHCCCCC
ALLHALDARIGATVERARALDAGLREQADALAPRWARLVEVTRQLGTIGDPQARLANASV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
YLEAFGHLVVAWLWLDVTLAAHGQADDFHDGKRAAARYFFNWELPKVDAQLDLLARVDTT
HHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHEEEEECCCCCCCCHHHHHHHCCCC
TLDMRDAWF
EECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]