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The map label for this gene is xdhA [C]

Identifier: 78065942

GI number: 78065942

Start: 1433022

End: 1435346

Strand: Direct

Name: xdhA [C]

Synonym: Bcep18194_A4471

Alternate gene names: 78065942

Gene position: 1433022-1435346 (Clockwise)

Preceding gene: 78065941

Following gene: 78065943

Centisome position: 38.79

GC content: 70.37

Gene sequence:

>2325_bases
ATGAGCGCGCCCGAACTCTCCGTCCATAACGAAAGCCGCCGCGCGCTGCTGCTCGGCTTCGCATCCGGCGGGCTGCTGCT
CGCGTTCGGCGTGCCGTCGCTCGTGTGCGCAGCCGTGCCGGTGCAGCCGCCCGTCAGCGCGAATCCGCAGTATGGCGGCG
CAGGGATGCCGCACGGGTTGCGCGACGATCCGCACCTGTTCGTCGCGATCGCGCCGGACGGCACGGTCACCGTGACCTGC
ATCCGCTCCGAGATGGGGCAGGGCGTGCGCACGAGCGTCGCGCTCGTGGTGGCGGACGAGCTGGGTGCCGACTGGGCACG
CGTGAAGGTCGCGCAGGCCGTCGGCGACGAGCCGCGCTACGGCAACCAGAACACCGACGGATCGCGCAGCCTGCGCCAGA
GTTTCGCCGCGCTGCGCCGCGCGGGCGCAGCCGCGCGCACGATGCTCGAACAGGCGGCTGCCGCGGCGTGGGGCGTCGAT
ACGCGTCAGGTCAAGGCGACGGTGCATGAGGTCGTCGACACGAAGAGCGGGCGCAAGCTCGGCTTCGGCGAACTGGCGGC
GAAAGCGGCCGCGCTGCCGGCACCGGATCCGGCAACGGTGGCGCTGAAAGCGCCGGCCGAATTCCGCTATATCGGCAAGG
GCGAAACCGCGCTGATCGACGGGCGCGATATCGTCGGCGGCCGCGCGCACTACGGGATCGACACGCGGCTCGACGGGATG
CTGTATGCGGTCGTCGCACGCCCGCCGGCGTACGGTGACACGGTGGCGTCGTTCGACGCATCGGCGGCGGAGAAGCTGCC
GGGTGTCGTCAAGGTCGTGCCGCTCGCGCCGACGCCGCTGCCGTCGGGATTCCAGCCGCTCGGCGGCGTGGCCGTCGTCG
CGCACGATACGTGGACGGCGATCCAGGCGCGTGCGCAGCTGAAGATCGACTGGAAGCGCGGGCCCCATGCGAACTACGAT
TCGGCCGCCTATCGCAAGACGCTCGAAGCGGCTGCCGCGCAACCGGGCGACGTGATCCGCAATGATGGCGACGCGGCCAC
GGCGCTCGCCGGCGCCGCGAAGCGCGTGCGTGCGACTTACTACATCCCGCATCTCGCGCACGCGACGATGGAGCCGCCGG
CGGCCGTCGCGCGCGTGGCGGACGGCCGCTGCGAAGTGTGGACCTGCACGCAGGCGCCGCAGACCACGCGCGACGAGGTC
GCGAAAGCGCTCGGGTTGCCGACGGAGCGCGTGACGGTCAACGTGACGCTGCTCGGCGGCGGTTTCGGCCGCAAGTCGAA
ACCCGATTACGTGGTGGAGGCGGCGCTGCTGTCGAAGGCGGTCGGCGCGCCCGTCAAGCTGACGTTCACGCGCGAGGACG
ACATCGCGCACGACTATTTCCACGCGGTGTCGCTCGAGGCGTTCGAGGGCGGGATCGATGCATCGGGGAAAGTGGTCGCG
TGGCAGCATCGCACGGTCGCGCCGTCGATCCAGTCGACGTTCCGGGCCGGCGTCGTGCATGAGCAGCCGGGCGAGCTCGC
GCAGGGGATTGCGGACCTGCCGTTCGCGATTCCGAACGTGCGAATCGAAAATCCGGCTGCGGAAGCGCATACGCGGATCG
GCTGGTTCCGCTCGGTCTACAACATCCCGCATGCGTTCGGGATCCAGAGCTTCGTGTCGGAGCTGGCGCATGCGGCCGGT
CGCGACCCGAAGGATTTCCTGCTCGAACTGATCGGGCCTGCGCGGCGATTCGAGCCGCACATCACGGTGAAGAACGTGAA
CTACGGCGAGGATCCGGCGCTGTATCCGGTCGATACCGGCCGGCTGCGGCGCGTGGTCGAGACGGTCGCGCGCGAGGCCG
GCTGGGGGCGCAAGCTGCCGAAGGGGTACGGGCTCGGGATCGCCGCGCATCGCAGCTTCGTGTCGTACACGGCGGCGGTG
TGCGAGGTGCAGGTCGATGCCGACGGCAAGATCACGGTGCCGCGGGTCGACATCGCGATCGACTGCGGGCCGCAGGTCAA
TCCGGAGCGGGTACGCTCGCAGCTCGAGGGCGCGGTGGTGATGGGGCTCGGCATCGCGCTGCACGGCGAGATCACATTCA
AGGACGGCCATCCGGAGCAGAGCAACTTCAACGGCTTCCAGGTGCTGCGCATGAACGAGGCGCCGCGCGAAATCCGTGTG
CATCTCGTCGCACCGGACGATTTTGCGACCCCGCTCGGCGGCGTGGGCGAGCCGGGCCTGCCGCCCGTTGCGCCGGCGCT
GACCAATGCGATCTTCGCGGCGACCGGCACGCGCATCCGCAGCCTGCCGGTTGCCGACCAGCTCGCGAAGCCCCGCGCGG
GGTGA

Upstream 100 bases:

>100_bases
CCGACATCGACGATGCGATGTCCGGCAACATCTGCCGCTGCGGCACCTATACGCGCATTCGCGCGGCGATTCGCCTAGCC
GTGCGCCGCGGAGGTGCCGC

Downstream 100 bases:

>100_bases
CACAATCCCCAGGCCGGGCCGCATCGTGCGGCCCGGTACGCATCCATCCTTGAACAAGGAGTGTCGACGTGGCCTCATCC
GATGTCAGCGTGAAGCAGGC

Product: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding

Products: NA

Alternate protein names: ALDH [H]

Number of amino acids: Translated: 774; Mature: 773

Protein sequence:

>774_residues
MSAPELSVHNESRRALLLGFASGGLLLAFGVPSLVCAAVPVQPPVSANPQYGGAGMPHGLRDDPHLFVAIAPDGTVTVTC
IRSEMGQGVRTSVALVVADELGADWARVKVAQAVGDEPRYGNQNTDGSRSLRQSFAALRRAGAAARTMLEQAAAAAWGVD
TRQVKATVHEVVDTKSGRKLGFGELAAKAAALPAPDPATVALKAPAEFRYIGKGETALIDGRDIVGGRAHYGIDTRLDGM
LYAVVARPPAYGDTVASFDASAAEKLPGVVKVVPLAPTPLPSGFQPLGGVAVVAHDTWTAIQARAQLKIDWKRGPHANYD
SAAYRKTLEAAAAQPGDVIRNDGDAATALAGAAKRVRATYYIPHLAHATMEPPAAVARVADGRCEVWTCTQAPQTTRDEV
AKALGLPTERVTVNVTLLGGGFGRKSKPDYVVEAALLSKAVGAPVKLTFTREDDIAHDYFHAVSLEAFEGGIDASGKVVA
WQHRTVAPSIQSTFRAGVVHEQPGELAQGIADLPFAIPNVRIENPAAEAHTRIGWFRSVYNIPHAFGIQSFVSELAHAAG
RDPKDFLLELIGPARRFEPHITVKNVNYGEDPALYPVDTGRLRRVVETVAREAGWGRKLPKGYGLGIAAHRSFVSYTAAV
CEVQVDADGKITVPRVDIAIDCGPQVNPERVRSQLEGAVVMGLGIALHGEITFKDGHPEQSNFNGFQVLRMNEAPREIRV
HLVAPDDFATPLGGVGEPGLPPVAPALTNAIFAATGTRIRSLPVADQLAKPRAG

Sequences:

>Translated_774_residues
MSAPELSVHNESRRALLLGFASGGLLLAFGVPSLVCAAVPVQPPVSANPQYGGAGMPHGLRDDPHLFVAIAPDGTVTVTC
IRSEMGQGVRTSVALVVADELGADWARVKVAQAVGDEPRYGNQNTDGSRSLRQSFAALRRAGAAARTMLEQAAAAAWGVD
TRQVKATVHEVVDTKSGRKLGFGELAAKAAALPAPDPATVALKAPAEFRYIGKGETALIDGRDIVGGRAHYGIDTRLDGM
LYAVVARPPAYGDTVASFDASAAEKLPGVVKVVPLAPTPLPSGFQPLGGVAVVAHDTWTAIQARAQLKIDWKRGPHANYD
SAAYRKTLEAAAAQPGDVIRNDGDAATALAGAAKRVRATYYIPHLAHATMEPPAAVARVADGRCEVWTCTQAPQTTRDEV
AKALGLPTERVTVNVTLLGGGFGRKSKPDYVVEAALLSKAVGAPVKLTFTREDDIAHDYFHAVSLEAFEGGIDASGKVVA
WQHRTVAPSIQSTFRAGVVHEQPGELAQGIADLPFAIPNVRIENPAAEAHTRIGWFRSVYNIPHAFGIQSFVSELAHAAG
RDPKDFLLELIGPARRFEPHITVKNVNYGEDPALYPVDTGRLRRVVETVAREAGWGRKLPKGYGLGIAAHRSFVSYTAAV
CEVQVDADGKITVPRVDIAIDCGPQVNPERVRSQLEGAVVMGLGIALHGEITFKDGHPEQSNFNGFQVLRMNEAPREIRV
HLVAPDDFATPLGGVGEPGLPPVAPALTNAIFAATGTRIRSLPVADQLAKPRAG
>Mature_773_residues
SAPELSVHNESRRALLLGFASGGLLLAFGVPSLVCAAVPVQPPVSANPQYGGAGMPHGLRDDPHLFVAIAPDGTVTVTCI
RSEMGQGVRTSVALVVADELGADWARVKVAQAVGDEPRYGNQNTDGSRSLRQSFAALRRAGAAARTMLEQAAAAAWGVDT
RQVKATVHEVVDTKSGRKLGFGELAAKAAALPAPDPATVALKAPAEFRYIGKGETALIDGRDIVGGRAHYGIDTRLDGML
YAVVARPPAYGDTVASFDASAAEKLPGVVKVVPLAPTPLPSGFQPLGGVAVVAHDTWTAIQARAQLKIDWKRGPHANYDS
AAYRKTLEAAAAQPGDVIRNDGDAATALAGAAKRVRATYYIPHLAHATMEPPAAVARVADGRCEVWTCTQAPQTTRDEVA
KALGLPTERVTVNVTLLGGGFGRKSKPDYVVEAALLSKAVGAPVKLTFTREDDIAHDYFHAVSLEAFEGGIDASGKVVAW
QHRTVAPSIQSTFRAGVVHEQPGELAQGIADLPFAIPNVRIENPAAEAHTRIGWFRSVYNIPHAFGIQSFVSELAHAAGR
DPKDFLLELIGPARRFEPHITVKNVNYGEDPALYPVDTGRLRRVVETVAREAGWGRKLPKGYGLGIAAHRSFVSYTAAVC
EVQVDADGKITVPRVDIAIDCGPQVNPERVRSQLEGAVVMGLGIALHGEITFKDGHPEQSNFNGFQVLRMNEAPREIRVH
LVAPDDFATPLGGVGEPGLPPVAPALTNAIFAATGTRIRSLPVADQLAKPRAG

Specific function: Presumed To Be A Dehydrogenase, But Possibly An Oxidase. Participates In Limited Purine Salvage (Requires Aspartate) But Does Not Support Aerobic Growth On Purines As The Sole Carbon Source (Purine Catabolism). Deletion Results In Increased Adenine Sensit

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789230, Length=391, Percent_Identity=25.0639386189258, Blast_Score=74, Evalue=5e-14,
Organism=Escherichia coli, GI1786478, Length=135, Percent_Identity=33.3333333333333, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1789246, Length=129, Percent_Identity=32.5581395348837, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012368
- InterPro:   IPR006311 [H]

Pfam domain/function: PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.3 [H]

Molecular weight: Translated: 81800; Mature: 81669

Theoretical pI: Translated: 7.75; Mature: 7.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPELSVHNESRRALLLGFASGGLLLAFGVPSLVCAAVPVQPPVSANPQYGGAGMPHGL
CCCCCCCCCCCCCEEEEEEECCCCEEEEECCHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
RDDPHLFVAIAPDGTVTVTCIRSEMGQGVRTSVALVVADELGADWARVKVAQAVGDEPRY
CCCCEEEEEECCCCCEEEEEEEHHHCCCCCCEEEEEEEHHHCCCHHHHHHHHHHCCCCCC
GNQNTDGSRSLRQSFAALRRAGAAARTMLEQAAAAAWGVDTRQVKATVHEVVDTKSGRKL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCC
GFGELAAKAAALPAPDPATVALKAPAEFRYIGKGETALIDGRDIVGGRAHYGIDTRLDGM
CHHHHHHHHHCCCCCCCCEEEEECCCCEEEECCCCEEEECCCCCCCCCEECCCCCCCCCE
LYAVVARPPAYGDTVASFDASAAEKLPGVVKVVPLAPTPLPSGFQPLGGVAVVAHDTWTA
EEEEEECCCCCCCCHHHCCCHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEEEEECCHHE
IQARAQLKIDWKRGPHANYDSAAYRKTLEAAAAQPGDVIRNDGDAATALAGAAKRVRATY
EEEEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHHHEEEE
YIPHLAHATMEPPAAVARVADGRCEVWTCTQAPQTTRDEVAKALGLPTERVTVNVTLLGG
ECHHHHHCCCCCHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHCCCCCEEEEEEEEEEC
GFGRKSKPDYVVEAALLSKAVGAPVKLTFTREDDIAHDYFHAVSLEAFEGGIDASGKVVA
CCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHEEHHHHCCCCCCCCCEEE
WQHRTVAPSIQSTFRAGVVHEQPGELAQGIADLPFAIPNVRIENPAAEAHTRIGWFRSVY
EECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCEECCCHHHHHHHHHHHHHHH
NIPHAFGIQSFVSELAHAAGRDPKDFLLELIGPARRFEPHITVKNVNYGEDPALYPVDTG
CCCHHCCHHHHHHHHHHHHCCCHHHHHHHHHCHHHHCCCCEEEEECCCCCCCCEECCCHH
RLRRVVETVAREAGWGRKLPKGYGLGIAAHRSFVSYTAAVCEVQVDADGKITVPRVDIAI
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHEEEEEEEEECCCCEEEEEEEEEEE
DCGPQVNPERVRSQLEGAVVMGLGIALHGEITFKDGHPEQSNFNGFQVLRMNEAPREIRV
ECCCCCCHHHHHHHHCCEEEEEEEEEEEEEEEECCCCCCCCCCCCEEEEEECCCCCEEEE
HLVAPDDFATPLGGVGEPGLPPVAPALTNAIFAATGTRIRSLPVADQLAKPRAG
EEECCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEECCCCHHHHCCCCCC
>Mature Secondary Structure 
SAPELSVHNESRRALLLGFASGGLLLAFGVPSLVCAAVPVQPPVSANPQYGGAGMPHGL
CCCCCCCCCCCCEEEEEEECCCCEEEEECCHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
RDDPHLFVAIAPDGTVTVTCIRSEMGQGVRTSVALVVADELGADWARVKVAQAVGDEPRY
CCCCEEEEEECCCCCEEEEEEEHHHCCCCCCEEEEEEEHHHCCCHHHHHHHHHHCCCCCC
GNQNTDGSRSLRQSFAALRRAGAAARTMLEQAAAAAWGVDTRQVKATVHEVVDTKSGRKL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCC
GFGELAAKAAALPAPDPATVALKAPAEFRYIGKGETALIDGRDIVGGRAHYGIDTRLDGM
CHHHHHHHHHCCCCCCCCEEEEECCCCEEEECCCCEEEECCCCCCCCCEECCCCCCCCCE
LYAVVARPPAYGDTVASFDASAAEKLPGVVKVVPLAPTPLPSGFQPLGGVAVVAHDTWTA
EEEEEECCCCCCCCHHHCCCHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEEEEECCHHE
IQARAQLKIDWKRGPHANYDSAAYRKTLEAAAAQPGDVIRNDGDAATALAGAAKRVRATY
EEEEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHHHEEEE
YIPHLAHATMEPPAAVARVADGRCEVWTCTQAPQTTRDEVAKALGLPTERVTVNVTLLGG
ECHHHHHCCCCCHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHCCCCCEEEEEEEEEEC
GFGRKSKPDYVVEAALLSKAVGAPVKLTFTREDDIAHDYFHAVSLEAFEGGIDASGKVVA
CCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHEEHHHHCCCCCCCCCEEE
WQHRTVAPSIQSTFRAGVVHEQPGELAQGIADLPFAIPNVRIENPAAEAHTRIGWFRSVY
EECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCEECCCHHHHHHHHHHHHHHH
NIPHAFGIQSFVSELAHAAGRDPKDFLLELIGPARRFEPHITVKNVNYGEDPALYPVDTG
CCCHHCCHHHHHHHHHHHHCCCHHHHHHHHHCHHHHCCCCEEEEECCCCCCCCEECCCHH
RLRRVVETVAREAGWGRKLPKGYGLGIAAHRSFVSYTAAVCEVQVDADGKITVPRVDIAI
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHEEEEEEEEECCCCEEEEEEEEEEE
DCGPQVNPERVRSQLEGAVVMGLGIALHGEITFKDGHPEQSNFNGFQVLRMNEAPREIRV
ECCCCCCHHHHHHHHCCEEEEEEEEEEEEEEEECCCCCCCCCCCCEEEEEECCCCCEEEE
HLVAPDDFATPLGGVGEPGLPPVAPALTNAIFAATGTRIRSLPVADQLAKPRAG
EEECCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEECCCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2606906 [H]